TWAS
hub
About
Usage
Models
Genes
Traits
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Traits
:
Impedance of whole body
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chr5:52,157,374-53,672,849
Best TWAS P=2.01e-09 · Best GWAS P=2.13e-18 conditioned to 1.49e-07
52.2M
52.4M
52.6M
52.8M
53M
53.2M
53.4M
53.6M
0
5
10
15
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
YFS
Blood
NDUFS4
0.12
0.09
enet
30
0.13
1.3e-40
-5.2
-6.0
2.0e-09
0.51
1.00
0.00
TRUE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
NDUFS4
0.05
0.02
enet
8
0.03
1.4e-04
6.8
5.5
3.2e-08
-0.25
0.01
0.95
TRUE
1
GTEx
Muscle Skeletal
NDUFS4
0.07
0.05
lasso
2
0.04
1.2e-04
5.2
-5.1
3.0e-07
0.41
0.34
0.24
FALSE