Best TWAS P=2.01e-09 · Best GWAS P=2.13e-18 conditioned to 1.49e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | NDUFS4 | 0.07 | 0.05 | lasso | 2 | 0.04 | 1.2e-04 | 5.2 | -5.1 | 3.0e-07 | 0.41 | 0.34 | 0.24 | FALSE |
| 2 | YFS | Blood | NDUFS4 | 0.12 | 0.09 | enet | 30 | 0.13 | 1.3e-40 | -5.2 | -6.0 | 2.0e-09 | 0.51 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | NDUFS4 | 0.05 | 0.02 | enet | 8 | 0.03 | 1.4e-04 | 6.8 | 5.5 | 3.2e-08 | -0.25 | 0.01 | 0.95 | TRUE |