[Hub]/) : Traits : Impedance of whole body :

chr5:176,040,488-177,260,129

Best TWAS P=1.67e-16 · Best GWAS P=1.63e-24 conditioned to 0.0476

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RAB24 0.14 0.06 enet 14 0.09 4.2e-11 4.8 5.5 3.6e-08 -0.31 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum MXD3 0.33 0.06 lasso 6 0.05 9.1e-04 -6.0 -6.3 4.0e-10 0.32 0.27 0.12 FALSE
3 GTEx Artery Tibial MXD3 0.12 0.13 enet 5 0.12 7.0e-10 -5.9 -5.5 3.6e-08 0.29 0.94 0.06 FALSE
4 GTEx Brain Cerebellum MXD3 0.28 0.31 lasso 2 0.30 1.6e-09 -6.0 -5.9 3.1e-09 0.32 0.48 0.47 FALSE
5 GTEx Cells EBV-transformed lymphocytes RAB24 0.37 0.26 lasso 6 0.24 1.7e-08 -6.1 6.6 5.5e-11 -0.52 0.21 0.79 FALSE
6 GTEx Colon Sigmoid MXD3 0.35 0.27 lasso 9 0.29 6.3e-11 -6.0 -5.9 2.9e-09 0.39 0.44 0.55 FALSE
7 GTEx Colon Transverse PRELID1 0.31 0.28 lasso 4 0.26 1.1e-12 -5.9 5.9 3.0e-09 -0.34 0.97 0.03 FALSE
8 GTEx Esophagus Gastroesophageal Junction MXD3 0.17 0.12 lasso 3 0.08 9.5e-04 -5.9 -6.9 4.4e-12 0.34 0.06 0.29 TRUE
9 GTEx Esophagus Muscularis MXD3 0.27 0.20 enet 10 0.24 1.6e-14 -5.9 -5.6 2.3e-08 0.33 0.97 0.03 FALSE
10 GTEx Heart Left Ventricle MXD3 0.17 0.03 lasso 3 0.03 1.5e-02 -6.0 -6.0 2.2e-09 0.31 0.08 0.51 FALSE
11 GTEx Lung MXD3 0.20 0.12 lasso 10 0.12 1.8e-09 -5.9 -5.2 1.7e-07 0.31 0.89 0.10 FALSE
12 GTEx Pituitary MXD3 0.25 0.20 lasso 6 0.16 7.5e-05 -4.7 -5.5 3.7e-08 0.46 0.06 0.84 FALSE
13 GTEx Skin Not Sun Exposed Suprapubic MXD3 0.22 0.18 lasso 3 0.17 1.8e-09 -6.0 -5.4 6.6e-08 0.32 0.97 0.03 FALSE
14 GTEx Skin Sun Exposed Lower leg PRELID1 0.06 0.02 enet 5 0.03 3.4e-03 -5.9 6.1 1.4e-09 -0.43 0.06 0.91 FALSE
15 GTEx Stomach MXD3 0.21 0.03 lasso 7 0.08 1.4e-04 -6.1 -6.0 1.9e-09 0.51 0.06 0.89 FALSE
16 ROSMAP Brain Pre-frontal Cortex PRELID1 0.05 0.05 enet 10 0.05 1.8e-07 -5.9 6.1 1.0e-09 -0.52 1.00 0.00 FALSE
17 YFS Blood PRELID1 0.18 0.14 enet 18 0.18 4.0e-58 -6.0 6.9 6.9e-12 -0.39 1.00 0.00 FALSE
18 The Cancer Genome Atlas Breast Invasive Carcinoma MXD3 0.02 0.02 enet 4 0.02 1.8e-04 -6.0 -6.0 1.7e-09 0.52 0.22 0.74 FALSE
19 The Cancer Genome Atlas Colon Adenocarcinoma PRELID1 0.09 0.01 blup 38 0.05 1.1e-03 -5.8 5.5 3.2e-08 -0.16 0.05 0.37 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FGFR4 0.08 0.06 blup 46 0.07 2.5e-08 -10.2 5.8 7.5e-09 -0.75 0.00 1.00 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MXD3 0.05 0.00 lasso 6 0.00 6.9e-01 -6.4 -5.8 4.9e-09 0.22 0.02 0.09 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PRELID1 0.24 0.11 lasso 5 0.10 1.2e-11 -5.8 6.0 2.6e-09 -0.32 0.97 0.03 FALSE
23 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PRELID1 0.33 0.08 enet 4 0.08 2.7e-05 -5.9 6.1 1.4e-09 -0.33 0.48 0.07 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma MXD3 0.04 0.02 lasso 3 0.02 2.9e-03 -5.4 -6.0 2.1e-09 0.53 0.02 0.58 FALSE
25 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PRELID1 0.08 0.10 lasso 4 0.07 2.9e-04 -6.0 6.1 7.9e-10 -0.27 0.11 0.48 FALSE
26 The Cancer Genome Atlas Lung Adenocarcinoma MXD3 0.04 0.02 blup 41 0.02 5.6e-04 -5.4 -6.8 7.5e-12 0.52 0.02 0.91 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma FGFR4 0.11 0.04 enet 19 0.06 8.7e-07 -10.2 8.2 1.7e-16 -0.87 0.00 1.00 TRUE
28 The Cancer Genome Atlas Prostate Adenocarcinoma MXD3 0.04 0.02 blup 40 0.03 2.8e-04 -5.9 -7.0 2.1e-12 0.48 0.02 0.96 FALSE
29 The Cancer Genome Atlas Thyroid Carcinoma MXD3 0.05 0.04 lasso 5 0.04 1.8e-04 -6.0 -5.9 3.5e-09 0.53 0.20 0.68 FALSE