TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of whole body
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chr6:104,478,130-106,230,491
Best TWAS P=4.98e-14 · Best GWAS P=2.53e-22 conditioned to 6.88e-10
104.4M
104.6M
104.8M
105M
105.2M
105.4M
105.6M
105.8M
106M
106.2M
0
5
10
15
20
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
LIN28B
0.04
0.04
lasso
9
0.03
3.9e-05
7.69
7.5
5.0e-14
0.74
0.20
0.79
TRUE
2
GTEx
Lung
HACE1
0.09
0.00
lasso
4
0.00
6.2e-01
0.32
-5.1
2.7e-07
-0.57
0.05
0.31
FALSE