Best TWAS P=3.13e-10 · Best GWAS P=8.53e-11 conditioned to 0.0874
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Prostate | ASCC3 | 0.32 | 0.03 | lasso | 6 | 0.06 | 0.0112 | -2.4 | -5.9 | 3.4e-09 | 0.52 | 0.08 | 0.20 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | RP3-467N11.1 | 0.02 | 0.00 | blup | 287 | 0.01 | 0.0230 | 4.9 | -5.5 | 4.3e-08 | 0.83 | 0.07 | 0.44 | FALSE |
| 3 | The Cancer Genome Atlas | Esophageal Carcinoma | ASCC3 | 0.11 | 0.07 | blup | 131 | 0.07 | 0.0024 | 4.6 | 5.8 | 5.9e-09 | -0.90 | 0.08 | 0.71 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | ASCC3 | 0.06 | 0.05 | lasso | 1 | 0.04 | 0.0002 | -6.3 | 6.3 | 3.1e-10 | -0.94 | 0.04 | 0.94 | TRUE |