TWAS hub - HACE1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1360	0.0350	6.4e-10	0.104	0.101	0.114	0.111	0.104	1.4e-12	2.4e-12	8.8e-14	2.1e-13	1.3e-12
2	GTEx	Brain Caudate basal ganglia	0.2050	0.0820	3.9e-03	0.131	NA	0.052	NA	0.144	1.3e-04	NA	1.3e-02	NA	6.2e-05
3	GTEx	Brain Cerebellar Hemisphere	0.3580	0.0830	2.5e-06	0.428	NA	0.387	NA	0.373	2.8e-12	NA	5.8e-11	NA	1.6e-10
4	GTEx	Brain Cerebellum	0.2780	0.0770	1.1e-04	0.284	NA	0.255	NA	0.245	4.7e-09	NA	3.6e-08	NA	7.6e-08
5	GTEx	Brain Cortex	0.2930	0.1000	2.1e-04	0.044	NA	0.015	NA	-0.009	2.3e-02	NA	1.2e-01	NA	7.0e-01
6	GTEx	Brain Frontal Cortex BA9	0.2482	0.0875	4.0e-04	0.207	NA	0.180	NA	0.092	3.4e-06	NA	1.7e-05	NA	2.0e-03
7	GTEx	Cells EBV-transformed lymphocytes	0.4050	0.0900	6.7e-07	0.154	NA	0.123	NA	0.218	1.0e-05	NA	8.1e-05	NA	1.1e-07
8	GTEx	Cells Transformed fibroblasts	0.0700	0.0330	8.5e-03	0.017	NA	0.011	NA	0.014	1.8e-02	NA	4.3e-02	NA	3.0e-02
9	GTEx	Esophagus Mucosa	0.1650	0.0460	1.5e-05	0.034	NA	0.024	NA	0.041	2.5e-03	NA	9.3e-03	NA	9.6e-04
10	GTEx	Lung	0.0921	0.0457	7.3e-03	0.000	NA	-0.004	NA	-0.003	3.2e-01	NA	9.7e-01	NA	6.2e-01
11	GTEx	Nerve Tibial	0.1566	0.0613	1.4e-04	0.060	NA	0.055	NA	0.055	4.6e-05	NA	9.1e-05	NA	9.2e-05
12	GTEx	Thyroid	0.0760	0.0360	9.6e-03	0.056	NA	0.009	NA	0.036	3.8e-05	NA	6.7e-02	NA	8.9e-04
13	METSIM	Adipose	0.0443	0.0174	3.0e-04	0.032	0.024	0.027	0.024	0.021	1.3e-05	1.4e-04	6.2e-05	1.2e-04	3.9e-04
14	ROSMAP	Brain Pre-frontal Cortex	0.1645	0.0340	2.9e-14	0.157	0.135	0.157	0.152	0.164	1.1e-19	4.9e-17	1.0e-19	5.2e-19	1.4e-20
15	TCGA	Kidney Renal Clear Cell Carcinoma	0.0472	0.0296	8.1e-05	0.015	0.022	0.021	NA	0.011	7.9e-03	1.6e-03	1.9e-03	NA	1.7e-02
16	TCGA	Brain Lower Grade Glioma	0.0773	0.0452	7.9e-06	0.036	0.053	0.048	NA	0.035	5.5e-05	1.1e-06	3.5e-06	NA	6.6e-05
17	TCGA	Pancreatic Adenocarcinoma	0.1740	0.1100	9.3e-04	0.035	0.102	0.107	NA	0.048	1.4e-02	4.8e-05	3.2e-05	NA	4.2e-03
18	TCGA	Prostate Adenocarcinoma	0.0424	0.0307	7.4e-04	0.026	0.029	0.028	NA	0.030	7.9e-04	4.2e-04	5.5e-04	NA	3.8e-04
19	TCGA	Thyroid Carcinoma	0.0880	0.0590	3.8e-05	0.025	0.055	0.059	NA	0.045	1.5e-03	4.9e-06	1.9e-06	NA	3.3e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19
Age when periods started (menarche)	18.1	43.6	179.6	-8.6	3.1	-6.3	-6.4	-5.0	-6.5	-8.6	-7.3	-5.4	-13.4	-4.6	-6.8	-3.3	-7.1	-5.4	-4.8	-4.7	-5.3	-5.6
Relative age voice broke	14.2	21.6	46.9	-6.3	2.8	-4.6	-5.0	-1.8	-4.2	-6.4	-5.2	-3.6	-6.8	-3.5	-5.5	-3.0	-5.5	-4.3	-4.2	-3.1	-4.4	-4.7
Relative age of first facial hair	7.3	15.0	31.8	-5.3	1.8	-3.8	-4.0	-2.8	-3.2	-5.6	-4.4	-3.8	-4.9	-3.4	-4.6	-1.6	-4.5	-3.5	-3.5	-2.6	-3.4	-4.3
Guilty feelings	6.2	9.3	13.5	3.6	-3.5	3.4	3.4	0.8	3.4	3.1	3.5	-0.1	2.5	3.2	2.5	3.0	2.9	3.7	2.9	3.4	3.5	2.8
Comparative body size at age 10	5.6	15.4	21.8	4.7	-3.6	4.6	4.5	2.6	4.4	4.6	4.2	1.5	2.6	4.3	3.9	3.6	4.3	4.4	3.9	3.0	4.3	3.9
Past tobacco smoking	5.1	9.4	19.1	-2.2	4.4	-2.6	-2.7	-1.4	-3.2	-2.3	-4.1	2.9	-2.3	-3.7	-0.9	-3.5	-1.4	-3.9	-3.7	-3.7	-3.6	-2.8
Hearing difficulty/problems with background noise	4.9	7.8	11.8	2.9	-3.3	3.2	3.1	1.6	3.4	2.6	2.9	0.3	2.6	2.6	2.3	2.9	2.5	3.4	2.7	3.3	3.1	2.7
Smoking Status	4.8	11.4	24.9	2.3	-5.0	2.8	2.5	1.9	3.4	2.1	4.4	-3.5	2.0	4.3	0.4	4.1	0.9	4.5	4.4	4.2	3.7	3.3
Depressed Affect (Nagel 2018)	4.6	9.7	17.0	3.0	-3.2	3.4	3.3	0.2	3.2	3.4	4.1	0.1	3.7	3.0	2.7	3.1	2.9	3.4	3.5	2.9	3.5	3.4
Lung FVC	4.5	23.0	47.5	4.5	-6.5	4.2	3.8	3.5	4.9	2.8	6.2	-3.6	4.5	4.7	1.4	4.3	1.9	6.5	5.7	6.9	5.1	5.4
Miserableness	4.5	7.7	14.4	2.5	-3.8	2.8	2.6	1.7	3.3	2.3	3.6	-2.0	1.6	3.4	1.2	3.0	1.6	3.4	3.1	3.3	3.2	2.3
Forced expiratory volume in 1-second (FEV1), predicted	4.4	9.1	26.8	-3.9	2.0	-2.8	-2.9	-1.3	-2.1	-4.0	-3.6	-1.3	-5.2	-2.4	-3.4	-2.4	-2.8	-3.0	-2.6	-3.2	-2.7	-3.0
Standing height	4.3	43.0	127.7	-8.4	3.2	-6.4	-6.5	-3.3	-5.9	-8.9	-7.2	-5.4	-11.3	-4.4	-8.2	-4.4	-7.2	-5.8	-5.3	-5.4	-5.5	-6.3
Irritability	4.0	6.8	10.8	2.0	-3.2	2.8	2.5	0.4	2.9	2.3	3.3	-0.9	2.7	2.7	2.4	2.8	1.8	3.2	3.1	3.0	3.0	2.5
Neck or shoulder pain in last month	3.8	5.4	9.2	2.5	-2.5	2.4	2.6	0.8	2.0	3.0	3.0	0.4	1.4	2.8	2.1	2.9	2.2	2.5	2.8	1.1	2.7	2.2
Smoking status: Previous	3.8	5.7	10.6	2.3	-2.8	2.1	2.2	1.1	2.7	2.2	3.3	-1.3	3.0	2.6	1.2	2.1	1.6	2.8	2.9	2.4	2.6	2.7
Average weekly beer plus cider intake	3.8	5.5	10.1	2.5	-2.8	2.5	2.7	1.4	2.5	2.5	2.7	-0.2	-0.7	3.2	1.8	2.4	2.2	2.7	2.6	2.0	2.9	2.0
Neuroticism	3.6	8.6	17.1	2.6	-3.5	3.0	2.7	0.1	3.4	2.4	3.6	-1.6	3.1	2.9	1.6	2.7	1.8	3.7	3.5	4.1	3.1	3.6
Impedance of arm (right)	3.6	16.9	37.3	-6.1	2.8	-4.1	-4.3	-2.2	-4.7	-5.0	-4.2	-3.0	-5.3	-3.4	-3.8	-3.7	-4.4	-4.1	-3.6	-3.4	-3.8	-4.3
Ever had prostate specific antigen (PSA) test	3.6	4.2	7.1	2.2	-1.6	2.3	2.6	2.4	2.4	2.4	1.9	1.4	1.5	1.7	2.2	1.8	2.7	2.0	1.5	1.5	2.2	1.7
Height	3.4	65.8	234.1	-11.0	3.3	-7.6	-7.8	-4.0	-7.0	-10.9	-8.5	-7.4	-15.3	-4.4	-10.0	-4.0	-9.0	-6.9	-5.9	-7.3	-6.3	-7.9
Pain type(s) experienced in last month: Hip pain	3.3	4.1	7.4	2.7	-2.2	2.3	2.2	0.9	2.7	2.2	2.3	-0.1	0.6	2.3	1.4	2.1	1.8	2.3	2.5	1.2	2.4	2.0
Neuroticism (Nagel 2018)	3.2	7.5	13.9	2.6	-3.7	2.8	2.8	0.4	2.7	2.4	3.5	-0.8	3.4	2.8	1.7	2.4	2.1	3.4	2.9	3.1	3.0	2.8
Frequency of depressed mood in last 2 weeks	3.2	4.5	8.9	1.8	-2.2	2.1	1.9	0.8	2.5	2.3	2.8	-0.3	1.8	2.7	1.8	3.0	1.5	2.3	2.6	1.6	2.3	2.0
Heel bone mineral density (BMD) T-score, automated (left)	3.2	7.2	13.2	3.1	-2.2	3.4	3.1	0.9	2.3	3.3	2.8	1.7	3.6	2.8	3.1	2.1	3.1	2.6	2.3	1.8	2.8	2.4
Back pain experienced in last month	3.2	4.7	7.2	2.1	-2.4	2.6	2.5	2.0	2.6	2.7	2.3	0.2	1.1	2.2	2.1	2.2	2.3	2.5	1.8	2.3	2.6	1.1
Alzheimer’s Disease (in father)	3.1	3.4	7.6	-1.9	2.0	-2.0	-2.1	-1.1	-2.1	-2.1	-2.1	-0.5	0.4	-2.8	-1.9	-1.2	-1.8	-1.8	-2.0	-1.5	-2.2	-1.6
Heel bone mineral density (BMD) T-score, automated (right)	3.1	7.0	10.7	2.6	-2.8	3.3	3.1	0.8	2.8	3.2	3.0	0.6	2.5	2.8	2.7	2.4	2.8	3.0	2.6	2.2	3.1	2.2
Hearing difficulty/problems: Yes	3.0	4.5	7.0	2.3	-2.2	2.5	2.3	0.8	2.2	2.1	2.4	0.7	2.3	2.6	1.8	2.1	2.0	2.3	2.1	2.0	2.3	2.3
Mood swings	3.0	5.4	9.7	2.1	-2.7	2.5	2.4	1.2	3.0	2.3	3.0	-0.1	1.8	2.3	1.9	1.6	2.0	2.6	2.5	3.1	2.7	2.4
Illnesses of father: High blood pressure	3.0	3.8	6.4	-1.6	2.2	-2.5	-2.3	-1.4	-2.1	-1.6	-1.7	-0.4	0.4	-1.9	-1.5	-2.0	-2.0	-2.2	-2.1	-2.1	-2.4	-2.5
Impedance of arm (left)	2.9	13.5	29.9	-5.5	2.4	-3.5	-3.7	-2.0	-4.2	-4.4	-3.8	-2.6	-5.5	-3.0	-2.9	-3.8	-3.8	-3.7	-3.1	-3.0	-3.2	-3.7
Medication for pain relief, constipation, heartburn	2.9	4.9	11.0	-2.8	0.5	-2.0	-2.3	-0.5	-1.8	-3.3	-2.2	-3.0	-2.9	-1.6	-3.2	-2.5	-2.9	-1.4	-1.8	-0.1	-1.8	-1.9
Type 2 Diabetes (T2D) (2012)	2.8	3.2	6.1	-1.6	2.4	-2.0	-1.9	-1.5	-2.1	-1.3	-1.9	1.2	0.2	-1.9	-1.2	-1.9	-1.3	-2.3	-2.0	-2.5	-2.2	-1.3
Ever used hormone-replacement therapy (HRT)	2.8	3.5	7.0	2.2	-2.3	1.8	1.6	1.9	2.1	1.5	2.4	-1.1	1.1	2.2	1.1	1.2	1.0	2.4	2.1	2.7	2.0	1.9
Neuroticism score	2.8	5.9	14.3	1.8	-3.3	2.3	2.0	0.1	2.5	1.7	3.0	-2.0	2.4	2.7	1.2	2.4	1.1	3.2	2.6	3.8	2.6	2.4
Mother’s age at death	2.8	3.5	6.3	-2.0	2.5	-2.1	-2.3	-1.6	-2.5	-1.8	-2.0	0.5	-0.3	-1.8	-1.4	-1.3	-1.9	-2.3	-1.9	-2.0	-2.4	-1.5
Ovarian Cancer	2.7	3.5	8.0	1.8	-2.1	1.5	1.3	1.6	2.0	1.2	2.3	-1.0	2.8	1.7	0.7	2.7	0.6	2.1	2.5	1.7	1.8	2.4
Ever smoked	2.6	4.5	13.9	0.5	-3.7	1.8	1.4	1.5	1.8	0.4	2.3	-3.5	-0.2	3.0	-0.5	3.0	0.1	2.9	2.0	2.6	2.3	0.8
Cholesterol lowering medication	2.6	3.9	6.8	2.2	-2.5	1.9	1.8	2.1	1.8	1.8	2.3	-1.2	1.9	1.5	0.7	2.2	1.1	2.6	2.1	2.6	2.2	1.9
Heel T-Score	2.5	19.7	34.9	5.6	-3.6	4.8	4.7	3.0	4.6	5.1	4.7	1.6	5.9	3.2	4.6	3.0	4.5	5.0	4.0	5.0	4.4	4.8
Medication: Ibuprofen (e.g. Nurofen)	2.5	3.1	6.3	2.1	-0.9	1.9	2.1	0.6	1.9	2.5	1.7	2.1	1.1	1.8	2.2	1.6	2.4	1.4	1.7	0.3	1.7	1.7
Illnesses of father: Heart disease	2.5	3.5	6.0	2.1	-2.0	2.5	2.2	0.2	2.2	2.0	1.9	0.8	1.0	1.8	1.9	2.2	2.1	2.1	2.0	0.5	2.2	1.5
Long-standing illness, disability or infirmity	2.5	3.9	8.5	2.7	-1.9	1.9	2.1	0.2	2.9	2.6	2.4	0.1	1.3	1.9	1.6	1.6	1.8	2.0	2.0	2.2	2.1	1.8
Medication for cholesterol	2.5	3.8	7.3	-2.1	2.4	-2.0	-1.9	-1.6	-1.9	-1.9	-2.3	0.7	-2.0	-1.2	-1.1	-2.0	-1.4	-2.5	-2.2	-2.7	-2.2	-2.0
Pain experienced in last month	2.5	4.2	7.5	-2.6	1.5	-2.2	-2.2	-0.8	-1.9	-2.7	-2.5	-1.3	-2.5	-1.8	-2.1	-2.0	-2.2	-1.9	-2.0	-1.5	-2.1	-1.9
Medication for hormone replacement therapy	2.4	2.7	5.1	1.6	-2.3	1.8	1.9	1.1	1.8	1.5	1.8	-0.8	1.1	1.5	1.0	0.9	1.5	2.2	1.7	2.1	2.0	1.4
Average weekly fortified wine intake	2.4	2.8	5.5	-1.4	1.0	-1.5	-1.7	-1.3	-1.8	-2.4	-1.9	-1.3	0.2	-2.0	-1.9	-2.1	-1.7	-1.4	-2.3	-0.1	-1.8	-1.9
Medication: Aspirin	2.4	3.2	5.0	2.0	-2.0	1.7	1.7	1.1	1.9	1.9	2.1	0.0	1.9	1.9	1.3	2.2	1.3	2.0	2.0	1.9	1.9	2.0
Happiness	2.3	2.8	6.7	1.6	-1.7	1.3	1.4	-0.6	1.2	1.8	2.6	-0.9	1.7	1.3	1.2	1.4	1.1	1.9	2.3	2.1	1.9	2.4
Number of children fathered	2.3	2.6	5.7	1.9	-0.9	1.4	1.6	2.4	1.5	2.2	1.6	1.4	0.7	1.0	2.3	1.5	1.9	1.4	1.6	0.8	1.4	1.9
Coronary Artery Disease (CAD)	2.2	2.6	4.7	2.1	-0.8	1.4	1.4	1.7	1.1	1.9	2.2	-0.3	1.0	1.9	1.3	1.6	1.2	1.8	2.1	1.7	1.6	2.1
Number of treatments/medications taken	2.2	3.9	9.9	2.2	-1.1	1.6	1.9	0.4	2.3	2.8	2.4	1.0	3.1	1.6	2.3	2.5	2.0	1.6	2.1	0.9	1.8	2.0
Supplements: Glucosamine	2.2	2.9	8.5	1.9	-0.7	1.9	2.1	0.5	1.5	2.2	1.3	1.9	0.1	1.1	2.9	1.8	2.5	1.2	1.6	-0.0	1.8	1.7
Mineral and other dietary supplements	2.2	3.0	5.4	-2.1	1.3	-1.7	-2.1	-0.7	-2.0	-2.2	-1.6	-1.3	-0.0	-1.8	-2.3	-1.8	-2.3	-1.6	-1.9	-0.2	-2.0	-1.4
Medication: Cholesterol lowering	2.1	3.3	7.1	2.0	-1.9	2.2	2.2	-0.0	2.3	1.8	1.5	0.4	1.3	1.5	1.9	2.7	2.0	2.0	1.9	0.8	2.0	2.0
Depression (self-reported)	2.1	2.5	4.9	2.1	-1.2	1.6	1.5	0.9	2.2	1.8	2.1	0.4	1.3	1.9	1.4	1.3	1.3	1.5	1.6	1.8	1.5	1.6
Time employed in main current job	2.0	2.3	6.2	2.3	-0.1	1.6	2.0	0.6	1.1	1.9	0.8	2.4	1.1	0.9	2.5	1.1	2.5	0.6	0.8	-0.7	1.1	1.3
Medication: Lansoprazole	2.0	2.2	8.1	1.1	-1.0	1.2	1.4	-0.3	1.8	2.0	1.9	0.8	2.8	1.1	1.3	1.3	1.3	1.1	1.4	1.8	1.4	1.6
Angina (self-reported)	2.0	2.6	4.8	1.8	-1.9	1.9	1.9	1.4	2.2	1.7	1.5	-0.0	0.7	1.8	1.1	1.6	1.6	2.0	1.4	1.9	1.8	1.2
Had major operations	2.0	2.4	4.8	2.2	-1.6	1.6	2.0	0.9	1.5	1.8	1.6	0.8	1.9	1.6	0.8	0.8	1.8	1.9	0.8	1.9	1.7	0.8
Impedance of whole body	2.0	10.4	26.4	-4.9	2.2	-3.1	-3.3	-0.9	-3.7	-3.6	-3.1	-2.3	-5.1	-2.5	-2.4	-3.4	-3.3	-3.2	-2.5	-3.0	-2.8	-3.2
Crohns Disease (2017)	1.9	4.1	7.0	2.2	-1.9	2.0	2.2	0.7	2.3	2.5	2.4	0.7	-0.4	2.6	2.1	2.3	1.9	2.1	2.7	1.2	2.3	2.3
Crohns Disease (2012)	1.9	3.1	5.2	1.7	-1.6	1.7	1.8	0.3	2.2	2.2	2.3	0.6	0.4	2.0	1.9	1.8	1.6	1.7	2.3	1.3	2.0	2.2
Angina	1.9	2.5	4.8	1.8	-1.8	1.8	1.9	1.4	2.2	1.7	1.5	-0.1	0.8	1.7	1.1	1.5	1.5	2.0	1.3	1.9	1.8	1.1
Fed-up feelings	1.9	3.4	8.1	1.2	-2.3	1.5	1.5	-0.7	1.8	1.5	2.7	-1.0	2.9	1.5	1.2	2.0	0.9	2.2	2.2	2.5	1.9	1.9
Tinnitus: Yes, but not now, but have in the past	1.9	2.0	5.4	1.1	-2.0	1.2	1.1	0.8	1.2	0.9	2.1	-1.1	0.6	1.7	0.6	2.3	0.4	1.8	1.8	1.6	1.6	1.1
Smoking status: Current	1.9	3.0	8.1	0.5	-2.9	1.3	1.0	1.4	1.3	0.4	1.9	-2.4	-0.5	2.3	-0.3	2.7	-0.1	2.4	2.1	2.1	1.9	1.4
High cholesterol (Self-reported)	1.9	3.3	7.8	1.9	-2.4	2.0	1.9	1.6	2.1	1.4	1.7	-1.0	1.5	1.7	1.0	2.8	1.3	2.3	2.0	1.2	2.0	1.8
Depression (Nagel 2018)	1.8	2.7	5.3	1.6	-1.4	1.7	1.5	0.0	1.5	1.7	2.0	0.6	2.3	2.0	1.4	2.2	1.3	1.6	2.0	1.1	1.4	2.2
Seen doctor (GP) for nerves, anxiety, tension or depression	1.8	2.7	5.5	1.8	-2.2	1.4	1.5	-0.3	1.5	1.7	2.3	-0.6	2.3	2.0	0.9	2.3	0.9	1.9	1.5	1.7	1.8	0.9
Ever had bowel cancer screening	1.8	2.1	3.5	1.6	-1.4	1.6	1.6	1.2	1.0	1.7	1.6	1.0	1.6	1.9	0.9	1.6	1.5	1.6	1.1	1.4	1.6	1.1
Diverticular disease/diverticulitis (self-reported)	1.7	2.0	11.8	1.3	-1.0	1.4	1.2	0.7	1.0	1.3	1.5	1.1	3.4	1.0	1.2	1.4	1.2	1.2	1.1	0.8	1.2	1.4
High blood pressure (mother)	1.7	2.4	4.8	-1.5	1.5	-1.4	-1.4	-1.2	-1.6	-1.6	-2.1	0.0	-1.6	-0.8	-1.3	-2.2	-1.1	-1.7	-1.8	-1.8	-1.6	-1.8
Body mass index (BMI)	1.7	7.1	14.4	3.2	-2.2	2.6	2.8	1.3	2.7	3.4	3.3	1.1	2.3	2.3	2.4	3.8	2.7	2.8	2.8	1.9	2.8	2.8
Reason for reducing amount of alcohol drunk: Health precaution	1.7	1.9	5.0	1.6	-1.7	1.4	1.4	1.7	1.1	0.7	0.9	-0.5	1.5	1.1	0.6	1.2	1.1	1.9	1.3	2.2	1.5	1.6
Knee pain experienced in last month	1.7	2.6	5.1	1.8	-1.5	1.6	1.5	0.3	1.3	1.9	2.2	0.4	0.5	2.0	1.5	2.2	1.2	1.5	2.3	0.9	1.9	2.0
Systolic Blood Pressure	1.6	8.3	15.3	-3.6	2.9	-3.3	-3.5	-2.1	-3.9	-2.6	-2.5	-1.2	-3.1	-2.8	-2.1	-1.9	-3.3	-3.2	-2.5	-2.6	-3.2	-3.0
Hand grip strength (left)	1.6	4.3	11.8	-2.2	1.3	-2.0	-2.2	0.4	-2.0	-2.7	-2.2	-1.5	-3.4	-1.4	-2.9	-1.4	-2.3	-1.9	-1.6	-1.9	-2.0	-2.1
Vitamin and mineral supplements	1.6	2.2	5.1	1.7	-1.5	1.4	1.4	0.8	1.1	1.4	1.8	-0.0	1.7	1.5	0.5	0.9	1.1	1.8	1.6	2.1	1.5	2.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	6.0	1.1	-1.7	1.6	1.6	-0.1	1.7	1.7	1.6	-0.4	1.6	1.5	1.4	2.4	1.4	1.3	1.4	0.3	1.7	0.8
Mouth/teeth dental problems: Loose teeth	1.6	1.9	4.3	1.6	-2.1	1.6	1.7	0.3	2.0	1.0	1.4	-1.3	-0.5	1.7	0.8	1.0	1.4	1.6	1.1	1.2	1.9	0.6
Medication: Ibuprofen	1.6	1.9	4.2	1.7	-0.5	1.5	1.7	1.0	1.5	2.1	1.2	1.9	1.2	1.4	1.7	1.1	2.0	0.9	1.0	0.1	1.3	1.0
Irritable Bowel Disease (IBD)	1.5	3.6	7.7	2.1	-1.7	2.0	2.1	1.1	1.7	2.1	2.0	1.1	-1.0	2.4	1.9	2.8	1.9	1.8	2.4	0.3	2.2	2.0
Fasting Glucose	1.5	1.8	4.3	1.0	-1.0	1.4	1.5	1.7	2.1	1.3	1.2	0.5	-0.4	1.4	1.2	1.6	1.5	1.3	1.6	0.7	1.7	1.3
Alcohol usually taken with meals	1.5	2.5	7.3	-1.2	2.0	-1.1	-1.1	-2.6	-0.9	-0.8	-1.8	1.7	1.3	-2.1	0.1	-2.7	-0.3	-1.8	-2.2	0.0	-1.6	-0.9
Hair/balding pattern: Pattern 2	1.5	2.0	4.5	-1.9	0.6	-1.5	-1.6	-0.2	-1.5	-2.1	-1.4	-1.4	-0.8	-1.2	-2.1	-0.7	-1.9	-1.1	-1.6	0.4	-1.5	-1.3
Deep venous thrombosis (DVT) (self-reported)	1.5	1.9	4.5	-1.5	1.4	-1.1	-1.3	-1.3	-1.5	-1.2	-1.6	-0.0	-0.4	-1.8	-1.0	-1.6	-0.9	-1.5	-2.1	-0.6	-1.5	-2.0
Stomach or abdominal pain in last month	1.4	1.7	4.1	1.3	-0.3	1.1	1.1	-0.5	0.7	2.0	1.8	1.0	2.0	-0.0	1.5	1.8	1.3	1.0	1.6	0.4	1.1	1.8
Leg pain on walking	1.4	1.8	7.0	1.3	-1.4	1.0	1.3	0.5	1.7	1.3	1.6	0.2	-0.2	1.4	1.3	2.6	1.1	1.4	1.7	0.6	1.5	1.2
Supplements: Vitamin C	1.4	1.7	4.6	-1.5	1.9	-1.0	-1.0	-0.3	-1.6	-0.5	-1.4	1.3	-1.0	-0.8	0.7	-1.1	-0.3	-2.0	-1.4	-2.1	-1.2	-1.5
Sensitivity / hurt feelings	1.3	2.2	7.6	1.5	-2.0	1.6	1.5	0.2	1.1	0.9	1.6	-1.5	1.6	1.5	0.8	0.7	0.9	2.2	1.0	2.8	1.5	1.4
Current tobacco smoking	1.3	2.2	6.3	0.4	-2.5	1.1	0.8	1.6	1.1	0.0	1.2	-2.0	-1.1	2.0	-0.4	2.5	-0.2	2.0	1.6	1.7	1.5	0.9
Qualifications: None of the above	1.3	2.8	5.8	1.9	-1.0	1.4	1.7	0.1	2.3	2.2	1.8	1.3	1.2	1.7	2.4	2.1	1.7	1.3	1.8	0.9	1.6	1.5
Mouth/teeth dental problems: Dentures	1.3	2.1	4.9	1.5	-2.0	1.0	1.1	0.9	1.2	1.1	1.8	-1.8	-1.7	1.9	0.1	2.2	0.4	1.8	1.7	1.1	1.6	0.9
Qualifications: College or University degree	1.3	4.0	6.9	-2.1	1.6	-1.9	-2.1	-0.8	-2.5	-2.3	-2.5	-0.8	-1.3	-2.4	-2.6	-2.4	-1.9	-1.7	-2.4	-1.1	-2.0	-2.2
Ever had hysterectomy (womb removed)	1.2	1.3	12.0	1.2	-0.7	0.8	0.8	-0.2	0.3	1.1	1.4	0.3	3.5	0.2	0.5	0.3	0.7	0.9	1.1	0.5	0.9	1.4
Medication: Co-codamol	1.2	1.4	3.8	1.5	-1.4	1.4	1.1	1.7	1.2	1.0	1.0	-0.4	-0.3	1.9	1.0	1.1	0.8	1.4	1.1	1.0	1.2	0.7
Diabetes (mother)	1.2	1.5	5.7	-2.4	1.1	-1.6	-1.7	0.2	-2.0	-0.6	-0.2	-1.2	1.0	-0.8	-0.7	-0.8	-1.7	-1.3	-0.9	-0.3	-1.2	-1.1
Maternal smoking around birth	1.2	1.8	4.7	0.7	-1.5	1.1	0.9	1.1	2.0	1.2	1.4	-0.5	-2.2	1.5	0.9	1.9	0.6	1.3	1.8	0.3	1.3	0.8
Medication: Simvastatin	1.2	1.8	4.2	1.7	-1.7	1.3	1.2	1.1	1.5	1.1	1.4	-0.7	2.0	0.8	0.5	1.7	0.8	1.7	1.3	1.4	1.4	1.2
Fluid intelligence score	1.2	2.4	6.5	0.9	-2.5	1.6	1.5	2.3	1.0	1.1	2.0	-1.2	0.2	2.3	-0.5	1.1	0.7	2.1	1.6	1.4	2.1	0.8
Blood clot in the leg (DVT)	1.2	1.5	3.7	-1.3	1.1	-1.0	-1.2	-1.4	-1.3	-1.2	-1.4	-0.3	-0.1	-1.5	-1.0	-1.4	-0.9	-1.3	-1.9	-0.4	-1.3	-1.9
Emphysema/chronic bronchitis	1.2	1.3	2.6	1.2	-1.6	1.3	1.4	0.7	1.5	0.9	1.1	-0.8	0.0	0.8	0.7	1.1	1.1	1.5	1.2	1.3	1.4	1.2
Age started oral contraceptive pill	1.2	1.5	3.2	-1.0	0.4	-1.4	-1.2	-1.7	-1.5	-1.7	-0.9	-1.7	0.1	-1.2	-1.8	-1.4	-1.4	-0.6	-1.0	0.7	-0.9	-0.4
Major Depression (MDD)	1.1	1.3	5.8	1.1	-0.5	0.8	0.9	1.8	0.7	1.3	0.9	1.1	2.4	0.5	1.4	1.5	0.9	0.9	0.3	1.5	0.8	0.4
Neuroticism (2016)	1.1	1.5	8.0	0.8	-1.3	0.7	0.3	0.5	1.3	0.2	1.4	-1.7	2.8	0.6	-0.2	0.9	-0.2	1.4	1.5	1.7	0.7	1.5
Financial difficulties in last 2 years	1.1	1.4	4.3	0.8	-1.6	1.1	1.3	-0.8	1.5	0.7	1.1	-0.3	-0.5	1.2	0.9	2.1	0.9	1.3	1.7	-0.6	1.5	1.2
Diabetes (self-reported)	1.1	1.6	4.9	1.3	-0.8	0.8	0.9	0.6	1.3	1.8	1.6	0.2	2.2	0.7	1.3	1.6	0.9	1.1	1.7	1.2	1.1	1.6
Frequency of tiredness / lethargy in last 2 weeks	1.1	1.8	6.1	0.8	-1.8	1.1	1.1	-0.6	1.5	1.2	1.9	-0.7	0.7	1.5	0.8	2.5	0.6	1.6	1.8	1.2	1.5	1.2
Noisy workplace	1.1	1.4	4.4	-1.3	1.1	-1.4	-2.0	-0.1	-1.7	-1.6	-0.6	-0.9	0.2	-1.0	-0.8	-0.2	-2.1	-1.1	-0.7	-0.5	-1.5	-0.9
Illnesses of mother	1.1	1.4	3.1	1.7	-1.1	1.4	1.5	0.2	1.7	1.0	1.0	0.8	1.7	0.0	1.1	1.1	1.4	1.0	0.9	1.0	1.2	1.1
Pulse wave reflection index	1.1	1.4	3.1	1.8	-0.9	1.3	1.3	0.7	1.1	1.5	1.5	0.4	1.8	0.9	1.1	-0.5	1.4	1.1	1.1	0.5	1.3	1.2
Mouth/teeth dental problems: Mouth ulcers	1.1	1.7	4.8	-0.6	1.0	-1.0	-1.6	-0.6	-2.2	-1.6	-1.5	-0.1	1.0	-0.9	-1.8	-1.2	-1.5	-1.2	-1.6	-0.8	-1.5	-1.5
Medication: Atorvastatin	1.1	1.3	3.5	0.9	-0.8	1.7	1.4	1.5	0.9	1.3	0.8	0.9	0.2	1.1	1.7	1.9	1.4	0.9	0.8	0.1	1.1	0.8
Pack years of smoking	1.1	1.6	3.1	1.3	-1.7	1.5	1.5	1.0	1.8	1.0	0.7	0.1	-1.4	1.1	0.9	1.0	1.2	1.6	1.1	1.4	1.6	0.9
Bipolar Disorder or Schizophrenia	1.0	2.4	12.9	-2.2	1.2	-1.5	-1.3	-1.3	-0.2	-1.3	-2.0	-0.4	-3.6	-1.4	-1.2	-0.9	-1.1	-1.4	-1.5	-1.3	-1.2	-1.4
Mean Putamen Volume	1.0	1.2	2.3	1.5	-1.2	1.3	1.3	0.9	1.2	1.1	1.0	0.6	0.3	0.7	0.7	0.9	1.2	1.4	1.2	1.0	1.4	0.7
Hand grip strength (right)	1.0	2.8	12.2	-2.0	-0.2	-1.2	-1.4	-0.4	-1.7	-2.3	-1.3	-2.4	-3.5	-0.5	-2.6	-0.6	-2.0	-0.7	-0.9	-0.8	-0.9	-1.5
Ever highly irritable/argumentative for 2 days	1.0	1.2	8.0	1.0	-0.7	0.2	0.1	-0.2	0.2	1.1	2.0	-0.8	2.8	1.6	0.4	0.8	-0.0	0.6	0.9	1.6	0.7	0.7
Number of full brothers	1.0	1.3	6.1	0.9	-0.4	1.4	1.4	2.5	1.1	1.3	0.4	1.0	-1.3	1.1	1.2	0.8	1.7	0.4	-0.1	-0.2	1.0	-0.2
Medication: Seretide 50 evohaler	1.0	1.1	3.9	0.9	-1.1	0.6	0.5	1.0	1.0	0.6	1.3	-1.0	0.2	0.3	0.4	0.8	0.2	1.4	1.7	1.7	0.9	2.0
Medication: Aspirin	1.0	1.4	3.3	1.3	-1.3	1.1	1.1	0.7	1.3	1.2	1.2	0.1	1.2	1.1	0.9	1.8	0.9	1.3	1.2	1.1	1.2	1.3
Hearing aid user	1.0	1.2	4.1	-0.5	0.1	-1.0	-1.1	-1.2	-0.8	-1.5	-0.5	-1.9	1.4	-0.4	-2.0	-0.4	-1.6	-0.6	-0.7	0.4	-0.9	-0.7
Supplements: Fish oil (including cod liver oil)	1.0	1.4	2.7	1.7	-0.8	0.9	1.4	0.2	1.3	1.5	1.2	0.8	0.2	1.3	1.4	1.2	1.5	1.2	1.5	-0.2	1.3	1.0
Medication: Omeprazole (e.g. Zanprol)	1.0	1.3	4.1	1.1	0.1	0.9	1.0	-0.4	0.2	1.9	1.2	1.9	2.0	0.5	1.6	1.3	1.4	0.5	0.8	0.0	0.7	0.8
HbA1C	0.9	1.0	4.6	0.7	0.8	0.9	1.2	-0.6	0.5	1.3	0.3	2.2	0.5	0.1	1.9	0.8	1.6	0.3	0.2	0.1	0.8	0.4
BMI	0.9	5.0	13.0	2.5	-2.3	2.3	2.2	2.4	2.4	2.4	2.7	0.0	1.2	2.6	1.3	3.6	1.8	2.5	2.2	1.9	2.4	1.3
Taking other prescription medications	0.9	1.4	3.2	1.6	-0.5	1.0	1.1	-0.0	1.4	1.8	1.4	0.8	1.7	1.0	1.1	0.8	1.2	0.9	1.2	0.9	1.0	1.3
Hair/balding pattern: Pattern 3	0.9	1.4	3.0	1.3	-0.9	1.4	1.5	1.7	1.5	1.2	0.8	0.6	-0.3	1.1	1.2	1.2	1.5	1.1	0.9	0.7	1.2	0.9
Medication: Amlodipine	0.9	1.2	4.3	1.3	-0.1	0.6	1.0	-0.1	0.5	2.0	1.4	1.4	2.1	0.8	1.4	0.5	1.3	0.4	0.8	0.6	0.9	1.2
Medication: Ventolin 100micrograms inhaler	0.9	1.2	3.0	1.1	-0.9	1.0	1.0	0.5	1.0	1.3	1.3	0.5	0.7	1.3	1.2	1.0	1.0	1.1	1.7	-0.0	1.1	1.6
Leg fat percentage (left)	0.9	3.3	7.8	1.8	-1.6	1.6	1.8	1.5	1.7	2.4	2.5	0.1	0.4	1.5	1.7	2.8	1.7	1.9	2.3	1.0	2.1	2.0
Number of operations (self-reported)	0.9	1.3	9.5	1.7	-1.0	0.7	0.8	0.6	1.2	1.1	1.4	-0.4	3.1	0.7	-0.1	-0.3	0.7	1.1	0.5	1.4	0.8	0.3
Alzheimer’s Disease (including proxy)	0.8	1.2	2.6	-1.5	1.5	-1.2	-1.3	-0.5	-1.0	-1.3	-1.3	-0.3	-0.2	-1.6	-1.1	-0.6	-0.9	-1.0	-1.1	-1.1	-1.3	-0.9
Body Mass Index (BMI) (2010)	0.8	1.1	2.8	1.3	-1.0	1.1	1.0	-0.1	1.0	1.2	1.2	0.4	1.2	1.7	0.8	1.1	0.9	1.0	1.3	0.2	1.1	1.1
Supplements: Zinc	0.8	0.9	2.8	1.1	1.1	0.2	0.4	-0.2	-0.3	1.0	0.3	1.6	-0.5	0.1	1.5	-1.2	1.3	-0.4	0.9	-1.2	0.3	1.7
Pack years adult smoking proportion	0.8	1.3	3.4	1.0	-1.5	1.4	1.3	1.2	1.5	0.9	0.4	0.3	-1.8	1.0	0.8	0.8	1.0	1.4	0.8	1.2	1.4	0.6
Impedance of leg (right)	0.8	3.8	17.0	-3.1	1.0	-1.7	-1.9	0.6	-2.1	-2.0	-1.5	-1.8	-4.1	-0.8	-1.4	-2.2	-2.0	-1.7	-1.2	-1.6	-1.5	-1.9
Forced vital capacity (FVC)	0.8	3.0	18.5	-0.9	-2.5	-0.3	-0.5	0.6	0.7	-2.0	1.0	-4.3	-1.9	1.2	-2.7	0.7	-2.0	1.3	1.7	1.5	0.7	0.9
Gout (self-reported)	0.8	1.1	7.9	0.3	1.4	0.1	0.2	-0.7	-0.4	0.8	-0.4	2.8	0.5	0.1	1.5	0.5	1.1	-1.0	-0.2	-2.2	-0.3	0.2
Chronic bronchitis/emphysema (mother)	0.8	1.0	2.5	0.5	-1.0	1.0	0.9	1.4	0.7	1.0	1.0	-0.1	-0.8	0.8	1.3	1.6	0.7	1.0	1.1	0.6	1.0	1.0
Leg fat percentage (right)	0.8	3.0	8.0	1.6	-1.7	1.5	1.7	1.4	1.5	2.3	2.4	0.0	0.2	1.6	1.5	2.8	1.6	1.9	2.2	1.0	2.0	1.8
Loneliness, isolation	0.8	1.1	7.2	-0.1	-0.8	0.4	0.4	-2.7	1.1	0.7	1.1	-0.5	1.6	0.0	0.9	1.4	0.1	0.7	1.3	0.6	0.7	0.8
Bipolar Disorder (2018)	0.7	1.1	2.8	-1.5	0.7	-1.4	-1.3	-0.7	-0.4	-1.0	-0.8	-0.7	-1.7	-0.9	-1.3	-0.8	-1.3	-1.1	-0.5	-0.9	-1.0	-0.5
Schizophrenia (2018)	0.7	1.5	10.0	-1.6	0.9	-0.8	-0.6	-1.1	0.0	-0.9	-1.9	-0.0	-3.2	-1.1	-0.6	-0.1	-0.4	-0.8	-1.5	-1.0	-0.8	-1.4
Age at First Birth	0.7	1.0	3.5	-1.2	0.5	-0.8	-0.9	-0.7	-0.9	-1.5	-1.2	-0.6	-0.4	-1.9	-1.1	-1.3	-1.1	-0.6	-0.9	0.1	-1.0	-0.9
Schizophrenia (2014)	0.7	1.5	9.7	-2.0	1.0	-0.7	-0.6	-0.9	-0.1	-0.5	-1.7	0.6	-3.1	-1.0	0.2	0.1	-0.2	-1.1	-1.4	-1.2	-0.8	-1.2
Chronotype (morning person)	0.7	1.7	7.9	0.3	1.4	0.6	0.5	2.2	0.3	0.3	-1.6	2.8	-1.2	-0.7	1.4	-1.0	1.4	-0.9	-1.5	-1.7	-0.5	-1.2
Chronic bronchitis/emphysema (father)	0.7	0.8	2.6	0.5	-0.6	0.9	0.8	0.3	1.3	1.1	0.8	0.5	-1.6	1.6	0.9	0.3	0.8	0.4	0.9	-0.0	1.0	0.6
Impedance of leg (left)	0.7	3.2	15.4	-2.7	1.0	-1.5	-1.6	0.9	-1.8	-1.7	-1.5	-1.5	-3.9	-0.8	-1.0	-2.2	-1.6	-1.7	-1.1	-1.7	-1.3	-1.7
Had menopause	0.7	0.9	3.3	1.5	-1.4	0.6	0.9	-0.6	1.1	0.4	0.7	-1.2	0.3	0.9	0.3	0.5	0.6	1.2	0.7	1.8	1.1	0.8
Forced expiratory volume in 1-second (FEV1)	0.7	2.5	17.6	-0.9	-2.1	-0.5	-0.7	0.2	0.2	-1.9	0.8	-4.2	-1.4	1.1	-2.6	0.4	-2.0	1.1	1.3	1.2	0.5	0.5
Exposure to tobacco smoke at home	0.7	0.8	2.0	0.7	-0.5	1.1	1.0	0.1	1.0	1.2	0.6	1.0	0.8	1.1	1.1	0.1	1.2	0.8	0.2	1.4	0.9	0.6
Birth weight	0.7	1.4	4.6	-1.4	-0.7	-0.2	-0.3	0.2	-0.5	-2.1	-1.7	-2.1	-1.2	-0.9	-1.6	-0.3	-0.8	0.3	-1.8	0.8	-0.4	-1.7
Forced vital capacity (FVC), Best measure	0.7	2.5	13.7	-1.8	-1.3	-1.1	-1.2	-0.3	0.1	-2.4	-0.1	-3.7	-2.2	0.2	-2.9	-0.1	-2.4	0.1	0.4	0.7	-0.3	-0.5
Worry too long after embarrassment	0.7	1.1	5.8	0.2	-1.6	0.2	0.1	-0.4	0.5	-0.4	0.9	-2.4	1.0	1.1	-0.8	0.3	-0.7	1.4	0.6	2.4	0.6	0.4
Friendships satisfaction	0.7	0.9	2.0	1.1	-1.0	1.4	1.2	0.2	0.4	1.0	1.1	-0.2	0.7	1.0	1.0	0.7	1.1	1.0	0.8	0.6	1.2	0.9
Eye problems/disorders: Cataract	0.7	0.8	1.7	1.0	-0.9	0.8	0.9	-0.8	0.5	1.0	1.3	-0.3	1.1	0.9	0.7	1.0	0.8	1.0	1.1	0.3	1.0	1.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.4	7.3	1.2	-1.3	0.8	0.5	-0.2	1.1	0.1	1.5	-1.2	2.7	1.1	-0.3	0.6	-0.0	1.4	1.4	1.6	0.9	1.3
Financial situation satisfaction	0.7	0.9	2.4	0.7	-1.0	1.0	1.2	-1.0	0.8	0.6	0.6	0.0	-1.0	0.5	0.9	1.6	1.2	0.9	1.0	-0.4	1.1	1.0
Alcohol drinker status: Never	0.7	0.8	3.0	-0.0	1.6	-0.9	-0.5	-1.3	-0.0	0.1	-0.7	1.3	0.4	-1.3	0.1	-1.7	0.1	-1.2	-0.5	-0.7	-0.9	0.1
Reaction Time	0.6	1.2	4.5	0.4	-1.5	1.2	1.0	0.8	2.1	0.3	0.7	-0.7	0.1	1.7	0.9	1.5	0.5	1.2	1.4	0.7	1.1	1.1
Primary Biliary Cirrhosis	0.6	0.9	3.0	0.6	0.2	0.6	0.7	-1.5	0.7	1.3	0.7	1.7	-0.1	0.5	1.4	0.9	1.1	0.2	1.0	-0.9	0.6	1.0
Average weekly spirits intake	0.6	0.7	2.3	0.2	-1.5	1.2	0.9	0.9	1.2	0.2	0.8	-1.0	1.0	0.5	-0.0	0.7	0.4	1.0	0.7	0.2	1.0	0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	13.0	-1.2	-1.3	-0.8	-0.9	-0.6	0.1	-2.0	0.2	-3.6	-1.3	0.6	-2.5	-0.1	-2.0	0.4	0.5	0.8	-0.1	-0.4
Length of working week for main job	0.6	0.7	3.1	0.9	0.1	0.9	1.1	0.8	0.5	0.8	-0.1	1.8	-0.7	0.5	1.2	-0.1	1.4	0.1	-0.0	-0.3	0.5	0.3
Breastfed as a baby	0.6	0.7	4.1	0.4	-0.9	1.2	1.1	2.0	0.3	0.4	0.0	0.7	-0.3	1.1	0.5	0.7	1.0	0.7	-0.5	0.4	0.7	-0.9
Tense / ‘highly strung’	0.6	0.9	2.8	0.1	-0.7	0.2	0.1	-1.2	1.0	0.5	1.5	-1.2	1.2	1.2	0.4	1.0	-0.3	0.6	1.7	0.7	0.6	1.5
Medication: Paracetamol	0.6	1.0	9.3	0.8	0.1	0.4	0.7	-0.9	0.4	0.7	0.4	1.2	3.0	-0.1	1.1	1.3	0.9	0.1	0.1	-1.4	0.3	-0.2
High blood pressure (siblings)	0.6	0.8	5.4	0.1	1.5	-0.4	-0.2	0.3	-0.4	0.3	-0.6	2.3	-0.7	-0.5	0.5	-0.9	0.4	-1.1	-0.7	-1.7	-0.6	-0.5
Medication: Omeprazole	0.6	0.7	5.1	0.4	1.1	-0.2	-0.1	-1.1	-0.8	0.9	0.2	1.6	2.2	-0.6	0.6	0.2	0.4	-0.4	-0.2	-0.7	-0.4	0.0
Mean time to correctly identify matches	0.6	1.1	3.2	0.8	-1.3	1.1	0.9	0.5	1.8	0.2	0.6	-0.9	0.1	1.6	0.7	1.5	0.4	1.1	1.2	0.9	1.0	1.1
Leg fat mass (right)	0.6	2.4	8.6	1.5	-1.8	1.3	1.6	1.0	1.3	1.6	1.9	-0.3	-0.7	1.4	0.8	2.9	1.2	1.8	1.9	1.0	1.9	1.6
Number of full sisters	0.6	0.7	2.8	0.6	-1.0	1.1	0.8	1.5	1.2	0.5	0.3	0.1	-0.6	0.9	0.2	1.7	0.7	0.5	0.0	-0.3	0.8	-0.7
Age at last live birth	0.6	0.8	1.8	0.6	-0.6	0.9	1.2	-0.5	1.3	1.2	0.9	1.0	-0.3	0.8	0.9	0.6	1.3	0.6	1.1	-0.2	1.1	1.0
Family relationship satisfaction	0.6	0.7	1.4	1.1	-1.1	0.9	0.9	-0.4	0.4	0.8	1.2	-0.3	0.1	1.1	0.5	0.8	0.7	1.1	1.0	0.6	1.2	0.9
Commuting to job workplace: Walk	0.6	0.6	2.4	-0.1	0.1	-0.5	-0.5	0.1	-0.7	-1.2	-1.0	-0.3	0.6	-0.5	-1.1	-1.1	-0.6	-0.4	-1.5	0.6	-0.6	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.6	0.7	1.9	0.7	-0.6	0.5	0.5	1.4	0.8	1.0	1.1	0.2	0.2	1.1	0.7	0.7	0.4	0.9	1.1	0.8	0.7	1.0
Osteoporosis (self-reported)	0.6	0.8	2.2	-0.9	1.0	-0.9	-0.6	-0.7	-0.6	-0.6	-1.0	0.4	0.4	-1.0	-0.4	-1.5	-0.2	-1.3	-1.4	-0.3	-0.8	-1.1
Ever depressed for a whole week	0.6	0.7	5.5	-0.2	0.4	-0.9	-0.5	-2.3	-0.2	0.0	0.2	-0.1	2.2	-1.0	-0.0	-0.7	-0.4	-0.1	0.1	0.3	-0.4	0.5
Leg fat mass (left)	0.6	2.4	8.6	1.5	-1.7	1.3	1.6	0.9	1.3	1.7	2.0	-0.4	-0.6	1.4	0.8	2.9	1.2	1.8	1.9	0.9	1.9	1.7
Intelligence (Savage-Jansen 2018)	0.5	1.4	3.5	0.7	-1.9	1.2	1.4	0.6	1.2	1.2	1.5	-0.7	0.5	1.6	-0.1	1.5	0.9	1.7	1.4	0.3	1.8	0.3
Bipolar Disorder (2011)	0.5	0.5	2.4	0.6	-0.7	0.8	0.7	0.0	1.5	0.5	0.5	-0.1	0.6	0.7	0.2	0.1	0.7	0.7	0.6	0.7	0.7	1.1
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	2.0	0.2	-1.0	0.2	0.3	-0.7	0.5	0.6	1.2	-1.1	1.2	0.3	-0.4	0.4	-0.1	0.7	0.9	1.4	0.7	0.5
Severe depression (siblings)	0.5	0.5	1.9	-0.8	1.0	-0.8	-0.9	0.1	-1.2	-0.3	-0.3	0.4	0.7	-0.2	-0.2	-0.3	-0.7	-1.1	-0.4	-1.4	-0.8	-0.6
Heart attack	0.5	0.7	2.1	1.3	-0.0	0.7	1.0	0.6	0.6	1.0	0.2	1.4	0.8	0.4	0.9	0.9	1.3	0.2	0.3	-0.1	0.6	0.9
Illnesses of siblings	0.5	0.8	7.3	0.5	-0.8	0.6	0.3	-1.0	0.6	-0.4	0.4	-0.9	2.7	0.1	-0.0	0.3	-0.0	0.9	0.7	1.0	0.3	1.0
Trunk fat-free mass	0.5	3.0	13.5	-1.6	-0.2	-1.4	-1.4	-1.1	-0.7	-2.6	-1.7	-1.9	-3.7	-0.5	-3.3	0.3	-2.0	-0.9	-1.0	-0.9	-1.0	-1.4
Alcohol intake versus 10 years previously	0.5	0.8	4.7	-0.8	0.5	-1.2	-1.0	0.7	-0.7	-0.8	-0.4	-0.4	-2.2	-0.1	-0.7	-0.4	-1.0	-0.8	-0.0	-1.2	-0.6	-0.3
Father’s age at death	0.5	0.7	3.3	-0.6	-0.4	-0.5	-0.3	-0.5	-0.2	-1.1	-0.5	-1.8	1.0	-0.7	-1.6	-0.3	-0.7	-0.0	-1.0	0.6	-0.2	-1.4
Lung cancer (father)	0.5	0.5	3.4	-1.2	0.2	-0.9	-0.6	-1.9	0.0	-0.4	-0.2	-1.0	-0.8	-0.5	-0.9	0.1	-0.8	-0.6	0.0	-0.4	-0.4	-0.1
Trunk predicted mass	0.5	3.1	14.0	-1.7	-0.1	-1.5	-1.4	-1.1	-0.7	-2.7	-1.8	-1.9	-3.7	-0.6	-3.3	0.2	-2.0	-0.9	-1.1	-1.0	-1.0	-1.5
Headache pain in last month	0.5	0.8	3.3	1.4	-0.1	0.9	0.9	-0.6	0.7	0.6	0.4	1.6	1.8	0.1	1.2	-0.2	1.2	0.5	0.1	0.8	0.5	0.8
Medication: Allopurinol	0.5	0.7	4.2	0.9	0.7	0.4	0.5	-0.6	0.0	0.9	0.1	2.0	0.6	0.5	1.3	1.0	1.0	-0.3	0.3	-1.3	0.1	0.6
Pulse rate, automated reading	0.5	1.6	5.6	-1.5	1.4	-1.3	-1.1	-1.9	-1.3	-0.7	-1.3	0.9	-2.4	-0.7	-0.3	-0.6	-0.9	-1.3	-1.1	-1.4	-1.3	-1.1
Chest pain or discomfort	0.5	0.7	3.0	0.4	-0.9	1.2	0.8	1.4	1.3	0.3	0.6	-0.2	0.6	0.9	1.1	1.7	0.6	0.3	0.4	0.1	0.8	0.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	3.4	0.2	-0.7	-0.0	-0.0	1.5	-0.0	0.2	0.7	-0.6	1.8	0.2	-0.0	0.9	-0.4	0.9	0.4	1.4	0.3	0.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	3.5	0.9	-0.1	0.2	0.5	0.2	0.1	0.8	0.7	0.4	1.6	0.1	0.5	0.1	0.7	0.7	0.1	1.9	0.4	0.8
Illnesses of siblings: Diabetes	0.5	0.6	2.3	-1.1	0.3	-0.7	-0.6	1.1	-0.3	-0.6	-0.8	-0.7	-1.5	-0.6	-0.4	-0.6	-0.7	-0.5	-0.9	-0.2	-0.6	-1.2
Osteoarthritis (self-reported)	0.5	0.7	2.8	0.1	-0.7	0.9	1.1	0.5	0.3	1.2	0.4	0.7	-0.5	0.5	1.7	1.2	1.1	0.8	0.4	0.8	0.9	0.3
Unable to work because of sickness or disability	0.5	0.6	1.1	-0.9	0.5	-1.0	-0.8	-0.9	-0.1	-0.6	-0.8	-0.5	0.6	-0.8	-0.8	-1.0	-0.9	-0.8	-1.0	0.1	-0.8	-1.0
Commuting to job workplace: Cycle	0.5	0.6	3.1	0.9	-0.1	0.9	0.7	0.3	0.6	0.8	0.4	1.0	1.8	0.3	0.8	-0.6	0.9	0.5	0.3	0.9	0.4	0.8
Myopia	0.5	0.8	5.1	0.1	0.8	0.4	0.3	1.6	-0.2	0.6	-0.6	2.2	-1.7	0.2	1.3	0.3	0.8	-0.3	-0.4	-0.8	-0.1	-0.2
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.8	1.4	-0.2	0.9	1.1	0.7	0.6	0.9	0.1	1.2	0.7	0.5	0.8	0.8	1.3	0.4	0.2	0.1	0.6	0.8
Schizophrenia vs Biploar Disorder	0.4	0.5	4.9	-0.3	0.3	0.4	0.3	1.0	0.6	0.4	-0.5	0.9	-2.2	0.1	1.1	0.8	0.5	-0.2	-0.1	-0.4	0.1	-0.1
Triglycerides	0.4	0.6	1.8	-0.4	1.3	-0.9	-0.6	-1.2	-0.7	-0.2	-0.6	0.7	-1.0	-1.0	0.1	-1.1	-0.2	-1.3	-0.5	-0.5	-0.7	0.2
Blood White Count	0.4	3.3	8.9	-3.0	1.5	-2.3	-2.3	-1.5	-1.8	-1.4	-1.7	-1.0	-1.4	-1.6	-1.6	-0.5	-2.3	-1.9	-1.3	-1.7	-1.9	-2.5
Waist Hip Ratio (WHR)	0.4	1.7	11.2	-0.8	-1.1	-1.0	-1.2	-0.6	-0.6	-2.2	-0.4	-3.3	0.1	-0.1	-1.8	-0.0	-2.2	0.0	-0.2	1.4	-0.6	-0.3
Tanning	0.4	4.7	10.7	2.0	-2.7	3.0	2.6	3.3	2.5	1.5	1.8	0.1	-0.3	3.0	1.4	1.7	2.0	2.6	1.8	1.9	2.5	1.5
Townsend deprivation index at recruitment	0.4	0.6	1.5	1.0	-1.2	0.8	0.9	-0.4	1.1	0.8	0.9	-0.2	0.2	0.4	0.3	0.4	0.6	0.9	0.9	1.1	1.1	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	1.8	-0.1	-0.7	0.7	0.4	-0.0	0.7	0.5	1.0	-0.3	1.3	1.4	0.5	1.3	0.1	0.6	0.7	0.1	0.5	0.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.6	0.2	-0.6	1.0	0.8	1.0	0.5	0.7	0.4	0.4	1.3	0.2	0.9	0.3	0.8	0.6	-0.3	0.8	0.7	-0.4
Serious illness, injury or assault to yourself	0.4	0.5	1.8	0.0	0.9	-0.1	0.3	-0.1	-0.6	0.2	-0.9	1.3	-1.0	-0.7	0.5	-1.0	0.8	-0.7	-1.3	-0.5	-0.3	-0.7
Medication: Atenolol	0.4	0.5	1.4	-0.3	1.2	-0.4	-0.3	0.7	-0.0	0.0	-0.8	1.1	0.9	-1.0	-0.2	-0.7	0.2	-0.8	-1.0	-0.3	-0.7	-0.6
Medication: Levothyroxine sodium	0.4	0.6	4.9	0.2	-0.6	-0.3	-0.2	-0.4	0.2	0.2	0.9	-1.2	-0.2	0.6	-0.7	0.7	-0.7	0.7	0.8	2.2	0.3	0.9
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.0	-0.1	0.8	-0.3	0.0	-1.4	-0.4	-0.2	-0.8	1.0	1.1	-0.9	0.7	-0.2	0.4	-0.6	-1.0	-0.7	-0.5	-0.6
Number of live births	0.4	0.6	1.4	-0.8	0.9	-0.6	-0.5	-1.1	0.4	-0.7	-1.2	0.8	0.2	-1.2	0.2	0.2	-0.2	-1.0	-1.0	-0.4	-0.9	-0.8
Arm fat mass (right)	0.4	1.6	6.7	1.0	-1.5	1.1	1.3	0.6	1.0	1.3	1.6	-0.4	-0.9	1.2	0.4	2.6	0.9	1.4	1.6	0.6	1.6	1.2
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	2.1	-1.4	0.6	-0.8	-0.9	-0.4	-0.9	-1.0	-0.4	-0.4	0.3	-0.6	-1.2	-1.0	-1.0	-0.9	-0.7	-0.2	-0.8	-0.5
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	2.3	-0.9	0.5	-0.6	-0.6	0.5	-0.8	-1.3	-1.1	-0.3	-1.5	-0.6	-0.9	-0.7	-0.7	-0.6	-0.9	-0.4	-0.7	-1.0
Alcohol intake frequency.	0.4	0.9	1.8	-0.9	1.3	-1.3	-1.1	-0.4	-0.7	-0.3	-0.6	0.0	-1.2	-1.2	-0.4	-0.9	-0.8	-1.4	-1.0	-0.9	-1.0	-1.1
Comparative height size at age 10	0.4	2.0	8.4	-1.4	0.8	-1.4	-1.5	0.2	-0.6	-1.8	-1.4	-0.7	-2.9	-0.5	-1.9	-0.9	-1.5	-1.3	-0.8	-1.9	-1.2	-1.2
Whole body fat-free mass	0.4	2.1	8.6	-1.4	-0.3	-1.2	-1.1	-1.1	-0.5	-2.3	-1.4	-1.7	-2.9	-0.5	-2.9	0.6	-1.7	-0.6	-0.8	-0.6	-0.7	-1.0
Arm fat percentage (left)	0.4	1.5	5.4	0.7	-1.2	1.1	1.3	0.3	0.9	1.6	1.7	-0.1	-0.4	0.9	1.1	2.3	1.1	1.3	1.5	0.7	1.6	1.2
Diabetes diagnosed by doctor	0.4	0.7	4.1	1.0	-0.3	0.5	0.5	0.6	0.8	1.3	0.9	0.4	2.0	0.2	0.9	0.9	0.6	0.6	0.9	0.3	0.6	0.7
Arm fat mass (left)	0.4	1.8	7.0	1.1	-1.5	1.2	1.4	0.6	1.2	1.5	1.6	-0.2	-1.1	1.2	0.7	2.6	1.2	1.4	1.6	0.6	1.8	1.4
Number of self-reported non-cancer illnesses	0.4	0.8	4.6	1.2	0.1	0.6	0.6	-0.3	0.6	1.2	0.8	1.0	2.2	0.2	1.2	0.3	0.9	0.3	0.3	1.0	0.4	0.9
Wears glasses or contact lenses	0.4	0.4	1.1	0.9	-0.5	0.5	0.7	0.6	0.3	1.1	0.8	-0.0	0.3	0.9	0.6	0.9	0.7	0.6	0.3	0.7	0.7	0.3
Medication: Paracetamol	0.4	0.7	5.6	0.1	0.2	-0.3	0.1	-1.5	0.0	-0.1	-0.3	0.4	2.4	-0.9	0.3	0.8	0.3	-0.3	-0.5	-1.5	-0.2	-0.8
Diastolic blood pressure, automated reading	0.4	1.4	3.8	-1.1	2.0	-1.5	-1.4	-0.9	-1.7	-0.2	-0.7	1.0	-0.8	-1.0	-0.0	-1.0	-0.8	-1.6	-0.8	-1.7	-1.3	-0.8
Worry (Nagel 2018)	0.3	0.6	3.1	0.4	-1.0	0.8	0.7	-0.1	0.3	0.3	0.7	-0.6	1.8	0.8	0.1	0.2	0.3	1.0	0.6	1.1	0.7	0.8
Ulcerative Colitis (UC)	0.3	0.5	2.7	0.7	-0.5	0.6	0.7	0.4	0.0	0.5	0.3	0.9	-1.0	0.7	0.6	1.6	0.8	0.4	0.4	-0.5	0.8	0.2
LDL Cholesterol	0.3	0.6	3.0	-0.3	-0.4	-0.7	-0.3	-1.6	-0.1	-0.4	0.4	-1.3	1.7	-1.1	-0.1	0.4	-0.6	0.0	0.1	0.5	-0.0	0.3
Blood Eosinophil Count	0.3	2.2	4.8	1.5	-0.4	1.3	1.7	1.1	1.0	2.2	1.4	1.9	2.1	0.9	2.2	1.2	2.1	1.0	1.1	-0.4	1.4	1.2
Blood Platelet Count	0.3	3.4	9.7	-1.7	2.1	-2.1	-2.2	-2.9	-3.1	-1.4	-1.5	-0.1	-0.9	-2.3	-0.8	-1.9	-1.8	-1.9	-1.2	-1.4	-2.0	-1.1
Blood Red Count	0.3	2.7	7.2	-1.7	2.4	-2.4	-2.1	-1.3	-2.7	-1.2	-1.1	0.4	0.3	-1.9	-0.8	-0.6	-1.6	-1.9	-1.5	-1.2	-2.1	-1.0
Cardiovascular Disease	0.3	1.1	2.5	1.6	-0.9	1.1	0.9	1.0	1.2	1.3	1.3	0.0	1.4	1.2	0.6	1.1	0.8	1.0	1.3	0.7	1.0	1.1
Systolic blood pressure, automated reading	0.3	0.8	2.2	-1.2	0.3	-1.2	-1.1	-0.9	-1.3	-0.4	-0.1	-1.4	-1.5	-0.1	-0.7	0.4	-1.3	-0.6	-0.2	-0.8	-0.6	-1.0
Medication: Metformin	0.3	0.5	3.6	0.9	-0.2	0.3	0.4	-0.1	0.8	1.0	0.6	-0.2	1.9	-0.4	0.5	0.3	0.6	0.5	0.5	0.2	0.4	0.3
Leg fat-free mass (left)	0.3	1.5	6.0	-1.2	-0.2	-1.1	-1.0	-1.6	-0.6	-1.9	-1.0	-1.5	-2.2	-0.6	-2.5	0.7	-1.5	-0.5	-0.5	-0.4	-0.5	-0.6
Qualifications: CSEs or equivalent	0.3	0.4	2.4	0.0	0.7	0.5	0.3	0.7	0.4	0.8	0.3	1.5	0.5	0.2	1.0	0.8	0.7	-0.4	0.2	-1.1	-0.0	-0.1
Multivitamins +/- minerals	0.3	0.4	1.5	-0.4	0.1	-0.5	-0.4	-0.6	-0.1	-0.7	-0.8	-0.4	-1.2	-0.6	-0.3	-0.1	-0.5	-0.4	-0.4	-0.9	-0.4	-1.1
Sitting height	0.3	1.8	10.1	-0.4	-1.9	0.0	-0.0	-0.4	0.5	-1.2	0.6	-3.2	-2.7	1.1	-2.4	0.3	-1.0	1.0	1.2	0.1	0.8	0.3
Leg predicted mass (left)	0.3	1.6	6.3	-1.2	-0.2	-1.1	-1.0	-1.6	-0.7	-2.0	-1.0	-1.5	-2.2	-0.6	-2.5	0.7	-1.5	-0.5	-0.5	-0.4	-0.6	-0.6
Trunk fat mass	0.3	1.1	10.8	-1.2	-0.4	-0.7	-0.5	-0.4	-0.7	-0.7	-0.1	-1.7	-3.3	-0.3	-1.3	1.0	-0.9	-0.2	0.3	-0.6	0.1	-0.2
Nervous feelings	0.3	0.6	1.7	-0.7	-0.0	-0.7	-0.7	-0.9	-0.9	-1.2	-0.8	-1.3	-0.1	-0.6	-1.1	-1.1	-1.0	-0.2	-0.6	0.4	-0.5	-0.5
Had other major operations	0.3	0.4	1.6	-0.0	0.3	-0.3	-0.4	0.8	0.2	-0.7	-0.7	0.2	0.8	-1.3	-0.2	-0.6	-0.3	-0.5	-0.9	-0.2	-0.6	-0.8
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	4.8	0.2	0.4	-0.5	-0.4	-0.4	0.0	0.0	0.2	-0.5	2.2	-0.7	0.0	-0.2	-0.3	-0.4	-0.3	0.1	-0.4	-0.1
Mouth/teeth dental problems	0.3	0.5	1.9	-0.8	0.5	0.1	0.5	-0.3	0.3	0.4	-0.3	1.4	1.0	-1.3	1.0	-0.7	0.8	-0.1	-0.2	-0.0	-0.1	0.4
Medication: Ramipril	0.3	0.3	1.1	-0.6	0.9	-0.7	-1.0	-0.1	-0.7	0.1	-0.1	0.5	0.2	-0.2	-0.4	-0.3	-0.8	-1.0	-0.1	-0.7	-0.7	0.1
Falls in the last year	0.3	0.4	1.5	1.0	-0.5	0.3	0.3	0.9	0.8	0.6	0.7	0.1	1.2	0.5	0.1	0.3	0.2	0.6	0.9	0.6	0.5	0.7
Pulse rate	0.3	0.5	2.4	-1.0	0.7	-0.2	-0.2	-1.1	-0.9	-0.1	-0.7	1.6	-0.1	-0.2	0.6	0.1	0.0	-0.6	-0.8	-1.0	-0.5	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.4	2.6	-0.0	0.5	0.1	0.3	-1.6	0.7	0.3	-0.1	0.7	-0.9	-0.2	1.0	-0.1	0.6	-0.4	0.4	-0.4	0.1	0.9
Prospective memory result	0.3	0.4	2.1	0.8	0.3	0.6	0.5	0.7	0.4	0.4	-0.2	1.4	0.0	0.5	1.0	-0.2	0.9	0.2	-0.0	-0.2	0.2	0.4
Loud music exposure frequency	0.3	0.3	0.9	-0.6	-0.1	-0.5	-0.6	-0.7	-0.3	0.3	0.9	-0.9	0.9	0.2	-0.3	0.0	-0.8	-0.3	0.6	0.3	0.0	0.3
Hypothyroidism/myxoedema (self-reported)	0.3	0.5	3.5	-0.0	-0.8	-0.2	-0.1	-0.3	0.4	-0.1	0.6	-1.2	0.6	0.6	-0.5	0.7	-0.7	0.7	0.5	1.9	0.3	0.6
Medication: Blood pressure	0.3	0.5	4.3	0.3	0.4	-0.5	-0.4	-0.8	-0.2	1.1	1.0	0.3	2.1	0.1	0.3	0.1	-0.3	-0.1	0.6	0.7	-0.1	1.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.3	0.3	1.4	0.2	0.7	0.0	-0.1	1.2	-0.4	0.3	-0.5	1.1	-0.5	-0.2	0.3	-0.4	0.3	-0.5	-0.9	-0.3	-0.3	-0.8
Suffer from ‘nerves’	0.3	0.5	1.7	0.7	-1.1	0.7	0.5	0.1	-0.0	0.3	0.8	-1.1	0.7	1.1	0.0	0.5	-0.0	1.1	0.5	1.3	0.7	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	0.9	-0.4	0.8	-0.5	-0.4	0.6	-0.6	-0.6	-0.8	0.0	-0.1	-0.5	0.2	-0.3	-0.1	-0.5	-0.8	-0.9	-0.7	-0.7
Leg fat-free mass (right)	0.3	1.6	6.2	-1.3	0.0	-1.2	-1.1	-1.6	-0.7	-2.1	-1.3	-1.3	-2.0	-0.9	-2.5	0.4	-1.5	-0.7	-0.7	-0.6	-0.7	-0.7
Average weekly red wine intake	0.3	0.5	4.8	0.5	0.3	0.0	-0.1	-0.5	0.2	-0.6	-0.7	0.6	2.2	-0.5	-0.4	-1.1	0.1	-0.2	-0.6	0.2	-0.4	-0.0
Handedness (chirality/laterality): Left-handed	0.3	0.3	2.2	0.2	0.3	-0.2	-0.2	1.5	0.5	-0.0	0.2	0.3	-1.2	1.2	-0.6	0.1	-0.2	-0.4	0.2	-0.5	-0.2	-0.1
Asthma (self-reported)	0.3	0.6	3.2	-0.2	1.2	-0.1	-0.0	-0.4	-0.3	0.5	-0.6	1.8	-0.7	-0.6	1.3	-0.4	0.5	-0.9	-0.4	-1.5	-0.5	0.0
Whole body water mass	0.3	1.9	8.4	-1.2	-0.3	-1.1	-1.0	-1.0	-0.5	-2.1	-1.3	-1.7	-2.9	-0.4	-2.9	0.6	-1.6	-0.5	-0.7	-0.5	-0.6	-0.9
Leg predicted mass (right)	0.3	1.4	5.7	-1.2	-0.1	-1.1	-1.0	-1.5	-0.6	-1.9	-1.2	-1.2	-2.0	-0.8	-2.4	0.5	-1.4	-0.6	-0.7	-0.5	-0.6	-0.7
Tinnitus: Yes, now most or all of the time	0.3	0.4	4.3	0.1	0.4	-0.1	-0.4	1.2	0.2	-0.3	0.0	0.2	2.1	-0.6	0.5	0.3	-0.4	-0.4	-0.5	0.1	-0.5	-0.2
Medication: Lisinopril	0.3	0.4	2.8	-0.6	-0.7	-0.5	-0.4	0.3	0.6	-0.2	0.7	-1.7	0.0	0.4	-0.8	0.8	-0.9	0.5	0.6	0.6	0.1	-0.1
Basal metabolic rate	0.3	1.6	8.2	-1.1	-0.5	-0.9	-0.8	-0.9	-0.4	-1.8	-0.9	-1.6	-2.9	-0.2	-2.6	0.8	-1.4	-0.3	-0.4	-0.4	-0.3	-0.7
Vascular/heart problems diagnosed by doctor	0.3	0.8	1.8	-1.2	0.4	-0.6	-0.5	-0.3	-0.7	-1.3	-1.3	-0.5	-1.2	-0.8	-0.5	-1.1	-0.5	-0.7	-1.0	-1.1	-0.7	-1.2
Heart disease (siblings)	0.3	0.4	1.8	0.3	-0.8	0.1	0.1	0.6	0.4	0.6	0.8	-0.8	-0.8	0.8	-0.1	1.3	-0.2	0.4	0.3	0.5	0.6	-0.6
Alcohol drinker status: Previous	0.3	0.3	1.3	0.2	-0.2	0.4	0.3	0.8	0.4	1.1	0.8	-0.0	0.2	0.1	0.7	0.6	0.4	0.5	0.5	0.9	0.5	0.5
Alzheimer’s Disease (in mother)	0.2	0.3	3.0	-0.3	-0.1	0.1	0.1	0.5	0.4	-0.2	-0.2	0.3	-1.7	0.2	0.0	0.6	0.1	0.0	0.3	-0.7	0.1	0.4
Verbal and Numeric Reasoning (VNR)	0.2	0.6	2.0	-0.0	-1.4	0.8	0.8	1.3	0.6	0.3	0.8	-0.9	-0.6	1.0	-0.8	0.4	0.3	0.9	0.6	-0.1	1.1	-0.3
Breast Cancer	0.2	0.6	1.6	1.2	-1.0	0.6	0.3	1.0	0.9	0.2	0.7	-0.5	0.7	0.9	-0.3	0.4	-0.3	0.9	1.0	1.2	0.5	0.9
HDL Cholesterol	0.2	0.3	1.7	-0.4	0.3	0.0	-0.2	0.6	-0.2	-0.3	-0.7	0.4	0.9	-0.2	0.1	-0.3	-0.1	-0.4	-1.0	-0.6	-0.5	-1.3
Rheumatoid Arthritis	0.2	0.2	1.3	-0.4	0.4	-0.4	-0.4	-1.2	-0.5	-0.0	0.2	-0.0	0.8	-0.4	0.2	-0.0	-0.4	-0.5	0.1	-0.3	-0.3	0.5
Ulcerative Colitis	0.2	0.3	1.9	0.2	-0.6	0.4	0.3	0.5	0.9	0.3	0.4	0.3	-0.3	0.6	0.4	1.4	0.2	0.4	0.7	-0.3	0.5	0.2
Hypothyroidism (self reported)	0.2	0.5	2.7	-0.3	-0.7	-0.4	-0.4	-0.6	0.4	-0.2	0.7	-1.6	0.5	0.3	-0.6	0.5	-1.0	0.4	0.6	1.6	0.1	0.6
Type 2 Diabetes (T2D) (2018)	0.2	0.4	3.0	0.5	-0.1	0.2	0.3	0.1	0.8	0.8	0.5	-0.0	1.7	-0.4	0.6	0.4	0.4	0.2	0.8	-0.1	0.3	0.6
Lung FEV1/FVC ratio	0.2	1.0	8.4	0.5	-1.6	0.1	0.0	-0.9	-0.5	-0.7	0.7	-2.9	-0.6	0.8	-1.4	0.7	-0.7	1.0	0.6	0.7	0.7	0.3
Other serious medical condition/disability diagnosed by doctor	0.2	0.2	2.5	-0.0	0.3	-0.1	0.2	0.5	0.6	0.6	0.1	0.5	1.6	-0.3	0.5	-0.0	0.4	-0.2	-0.0	0.2	-0.1	0.1
Diabetes (father)	0.2	0.3	3.4	0.2	0.1	0.1	-0.0	1.8	0.9	-0.0	-0.1	-0.2	-0.5	0.4	0.2	-0.1	0.1	-0.1	0.1	0.2	-0.0	0.2
Trunk fat percentage	0.2	0.7	6.6	-1.0	-0.4	-0.4	-0.2	-0.1	-0.6	-0.1	0.4	-1.4	-2.6	-0.1	-0.6	1.1	-0.5	0.0	0.5	-0.2	0.4	0.1
High blood pressure	0.2	0.7	1.9	1.1	-0.5	0.6	0.4	-0.1	0.6	1.2	1.3	0.2	1.4	0.7	0.3	0.9	0.4	0.7	1.0	1.0	0.7	1.1
Hayfever, allergic rhinitis or eczema	0.2	0.4	3.8	-0.6	-0.8	0.4	0.3	-2.0	0.4	-0.4	0.0	-0.6	-0.1	-0.5	0.3	0.5	-0.0	0.7	0.1	1.0	0.4	0.4
Waist circumference	0.2	0.7	5.0	0.6	-0.9	0.7	0.9	0.4	0.8	0.5	0.6	-0.2	-0.7	0.4	0.5	2.2	0.7	0.7	0.6	0.5	1.0	0.5
Number of incorrect matches in round	0.2	0.3	1.0	0.4	0.5	-0.2	0.0	0.7	0.4	1.0	1.0	0.5	0.1	0.2	0.9	0.5	0.1	0.0	0.7	0.6	0.0	0.8
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.9	0.4	-0.7	0.4	0.3	0.5	0.7	0.2	0.6	-0.4	0.6	0.5	0.7	1.0	0.0	0.6	0.4	0.5	0.5	0.2
Allergy	0.2	0.5	2.4	-0.0	0.9	-0.4	-0.3	1.5	-0.4	0.2	-0.3	0.9	0.1	0.4	-0.3	-0.3	0.0	-0.8	-0.4	-1.4	-0.5	-0.9
Pain all over the body in last month	0.2	0.2	0.9	-0.2	0.6	-0.4	-0.0	0.5	-0.6	1.0	0.2	0.8	0.6	-0.1	0.5	-0.4	0.2	-0.5	-0.2	-0.6	-0.1	-0.5
Weight	0.2	0.9	7.3	-0.8	-0.5	-0.5	-0.4	-0.4	-0.2	-0.9	-0.2	-1.4	-2.7	0.0	-1.6	1.5	-0.8	-0.0	0.2	-0.7	0.1	-0.3
Arm fat percentage (right)	0.2	1.0	5.1	0.5	-1.0	0.8	1.0	0.3	0.6	1.3	1.4	-0.2	-0.4	0.7	0.8	2.2	0.8	1.0	1.1	0.4	1.3	0.8
Hip circumference	0.2	1.0	7.7	-0.1	0.4	0.4	0.9	0.4	0.1	0.8	-0.2	1.6	-2.8	0.1	0.8	1.4	1.3	-0.3	-0.1	-1.5	0.6	-0.3
Asthma	0.2	0.4	2.6	0.1	0.7	0.1	0.3	-0.0	-0.0	0.7	-0.2	1.6	-0.4	-0.4	1.4	-0.1	0.7	-0.5	-0.1	-0.9	-0.1	0.3
Pulse wave Arterial Stiffness index	0.2	0.2	0.8	0.0	-0.6	-0.4	-0.2	-0.2	-0.2	-0.5	-0.1	-0.7	-0.4	-0.0	-0.8	-0.9	-0.6	0.3	-0.1	0.3	-0.0	-0.3
Hair/balding pattern: Pattern 4	0.2	0.4	1.8	1.3	-0.4	0.5	0.4	-0.2	0.6	1.0	1.1	-0.1	0.1	0.5	0.6	-0.1	0.3	0.7	1.1	0.4	0.5	0.9
Birth weight of first child	0.2	0.3	2.6	-0.2	0.2	-0.4	-0.2	-1.6	-0.6	0.5	0.8	0.3	0.6	-0.2	-0.1	-0.2	-0.2	0.0	0.2	0.6	0.1	0.3
Peak expiratory flow (PEF)	0.2	0.5	2.1	0.6	-0.8	0.5	0.5	-0.1	0.0	0.8	1.5	-0.4	1.0	1.2	0.2	0.6	0.3	0.6	1.0	0.3	0.8	0.7
Body fat percentage	0.2	1.0	3.8	0.1	-1.1	0.6	0.8	0.5	0.4	1.0	1.3	-0.9	-1.5	0.7	0.5	2.0	0.5	1.0	1.3	0.4	1.2	0.9
Arm fat-free mass (right)	0.2	0.8	6.4	0.2	-1.1	-0.1	0.1	-0.0	0.6	-0.8	-0.1	-1.3	-2.5	0.5	-1.6	1.3	-0.5	0.6	0.4	0.2	0.5	0.2
Exposure to tobacco smoke outside home	0.2	0.3	2.1	0.1	-0.2	0.4	0.5	0.1	-0.1	0.6	0.4	1.4	-0.1	0.2	0.8	0.8	0.6	0.3	0.4	-0.1	0.4	0.3
Wheeze or whistling in the chest in last year	0.2	0.3	2.8	0.3	-0.7	0.3	-0.0	0.7	0.3	-0.4	-0.0	-0.7	0.0	0.3	0.1	1.7	-0.4	0.5	0.5	0.3	0.2	0.4
Migraine (self-reported)	0.2	0.2	1.3	-0.3	0.3	0.2	-0.1	0.0	0.0	-0.7	-0.8	0.6	0.4	-1.1	0.3	-0.0	0.1	-0.2	-0.6	-0.5	-0.4	-0.3
Whole body fat mass	0.2	0.9	4.9	0.0	-1.1	0.4	0.6	0.4	0.3	0.5	0.9	-1.0	-2.2	0.7	-0.2	2.0	0.2	0.8	1.0	0.2	1.1	0.7
Arm predicted mass (right)	0.2	0.8	6.1	-0.1	-1.0	-0.3	-0.1	-0.2	0.4	-0.9	-0.2	-1.4	-2.5	0.4	-1.8	1.2	-0.7	0.4	0.2	0.3	0.3	0.0
Commuting to job workplace: Car/motor vehicle	0.2	0.3	1.7	-0.5	-0.1	-0.3	-0.4	-0.4	0.2	-0.5	-0.0	-0.6	-0.6	0.2	-0.3	0.9	-0.5	-0.1	0.4	-1.3	-0.3	0.1
Hypertension (Self-reported)	0.2	0.5	1.3	1.1	-0.1	0.5	0.4	-0.2	0.5	1.1	0.9	0.5	1.1	0.5	0.5	0.8	0.5	0.4	0.7	0.7	0.4	0.9
Qualifications: nursing, teaching	0.2	0.3	1.4	-1.2	0.3	-0.3	-0.7	-0.2	-0.7	-0.9	-0.5	-0.4	-0.6	0.1	-0.2	-0.2	-0.7	-0.6	-0.5	-0.6	-0.5	-0.5
Medication: Gliclazide	0.2	0.2	1.3	0.1	-0.2	0.0	0.3	-0.2	0.5	1.1	0.8	0.0	0.5	0.2	0.4	0.4	0.4	0.3	0.8	0.3	0.5	0.6
Illnesses of father: None of the above (group 1)	0.2	0.2	0.9	-0.2	0.2	-0.5	-0.5	-0.1	-0.4	-0.4	-0.0	-0.2	-0.6	-0.1	-0.5	-0.9	-0.5	-0.2	-0.1	0.9	-0.3	0.4
Average weekly champagne plus white wine intake	0.2	0.3	1.1	-0.7	0.5	-0.5	-0.4	-0.3	-0.4	0.0	0.1	0.5	0.9	-0.1	-0.2	-0.8	-0.3	-0.5	-0.7	1.1	-0.4	-0.2
Ever taken oral contraceptive pill	0.2	0.2	1.0	0.1	-0.1	0.2	0.3	0.4	1.0	0.4	0.6	0.2	0.4	0.5	0.4	-0.3	0.3	-0.0	0.5	-0.0	0.4	0.5
Commuting to job workplace: Public transport	0.2	0.3	2.3	0.4	-0.2	0.0	0.1	1.5	0.6	-0.0	-0.1	-0.0	-0.8	-0.4	0.1	-0.4	0.1	0.3	0.0	0.9	0.2	0.3
Medication: Bendroflumethiazide	0.2	0.4	1.2	-0.6	0.7	-0.6	-0.9	-0.2	-1.1	-0.1	-0.1	-0.2	-0.3	-0.9	-0.3	-0.3	-0.8	-0.7	-0.6	-0.0	-0.6	-0.7
Arm fat-free mass (left)	0.2	0.9	4.9	-0.2	-1.1	-0.3	-0.1	-0.1	0.5	-1.1	-0.2	-1.5	-2.2	0.3	-2.0	1.4	-0.7	0.4	0.1	0.2	0.3	-0.2
Fractured/broken bones in last 5 years	0.2	0.3	1.9	0.5	0.4	-0.5	-0.2	-1.4	-0.0	0.0	0.3	0.1	-0.3	-0.0	-0.3	-0.7	-0.2	-0.5	0.5	-0.6	-0.1	0.6
Supplements: Calcium	0.2	0.3	1.1	0.4	0.2	0.4	0.6	0.1	0.4	0.4	-0.4	0.8	0.6	-0.2	0.6	-0.6	1.1	-0.1	-0.4	-0.7	0.3	-0.5
Basal cell carcinoma (self-reported)	0.2	0.2	0.8	0.9	-0.5	0.5	0.1	0.5	0.2	0.0	0.4	-0.5	0.5	0.2	-0.2	0.1	-0.1	0.7	0.5	0.9	0.3	0.7
Arm predicted mass (left)	0.2	0.9	3.6	0.2	-1.4	-0.0	0.2	0.1	0.7	-0.7	0.1	-1.5	-1.8	0.6	-1.9	1.6	-0.5	0.8	0.5	0.4	0.6	0.1
Lupus	0.1	0.1	0.3	-0.3	0.4	0.1	-0.1	0.4	-0.6	-0.0	0.1	-0.4	0.2	-0.5	0.0	-0.4	0.1	-0.1	-0.3	0.5	-0.1	0.1
Allergy or Eczema	0.1	0.4	4.6	-0.5	-0.2	0.2	0.3	-2.1	0.2	-0.1	-0.2	0.2	1.1	-0.6	0.4	-0.0	0.2	0.2	-0.3	0.3	0.1	0.5
Respiratory disease	0.1	0.3	1.2	0.0	1.1	-0.6	-0.4	-0.8	-0.4	0.4	-0.1	0.8	0.5	-0.2	0.4	-0.6	-0.0	-0.8	-0.0	-0.8	-0.6	0.3
Worrier / anxious feelings	0.1	0.2	0.9	-0.5	-0.4	-0.2	-0.2	-0.2	-0.5	-0.3	-0.1	-0.9	0.5	-0.1	-0.5	-0.7	-0.4	0.2	-0.3	0.9	-0.1	-0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.2	1.4	-0.6	0.1	-0.2	-0.0	-0.3	0.0	0.2	0.3	0.4	1.2	-0.4	-0.0	-1.2	0.1	-0.2	-0.1	0.3	0.1	-0.0
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.7	-0.1	0.4	-0.4	-0.7	0.2	-0.8	-0.0	0.0	-0.0	0.0	0.2	-0.3	0.7	-0.6	-0.5	-0.3	-0.2	-0.3	-0.6
Glaucoma (self-reported)	0.1	0.1	1.1	-0.1	0.2	-0.1	0.0	-1.0	-0.3	0.3	-0.1	0.5	0.3	0.1	0.1	-0.3	0.1	-0.2	-0.4	-0.2	-0.0	-0.6
Age at first live birth	0.1	0.2	0.8	0.7	-0.6	0.1	0.4	-0.4	0.5	0.2	0.6	0.0	0.5	0.3	-0.5	-0.1	0.3	0.4	0.8	0.0	0.6	0.9
Pulse wave peak to peak time	0.1	0.2	0.6	-0.7	0.7	-0.1	-0.3	-0.1	-0.3	-0.3	-0.5	0.0	-0.3	-0.4	0.0	0.5	-0.1	-0.7	-0.4	-0.6	-0.4	-0.3
Health satisfaction	0.1	0.2	0.6	-0.2	0.2	-0.3	-0.6	0.1	-0.1	-0.3	-0.1	-0.7	-0.8	-0.6	-0.3	-0.1	-0.6	-0.3	-0.1	0.4	-0.3	-0.1
Shortness of breath walking on level ground	0.1	0.1	0.7	0.3	-0.3	0.2	0.2	-0.4	-0.0	0.1	0.2	-0.3	0.2	-0.3	0.3	0.9	0.1	0.3	0.4	-0.1	0.3	0.3
Eye problems/disorders: None of the above	0.1	0.1	0.9	0.3	0.2	0.3	0.2	0.9	0.3	-0.1	-0.1	0.9	0.2	-0.0	0.4	0.2	0.3	-0.1	0.2	0.0	0.0	0.6
Heart disease (mother)	0.1	0.2	0.6	-0.8	0.7	-0.3	-0.6	0.4	-0.5	0.4	0.1	0.2	-0.2	0.0	0.4	-0.3	-0.5	-0.5	-0.3	0.1	-0.5	-0.3
Overall health rating	0.1	0.2	1.3	0.2	-0.2	-0.2	-0.1	-1.1	0.6	-0.1	-0.1	-0.6	-0.5	-0.4	-0.2	0.3	-0.2	0.1	0.3	0.2	0.0	0.3
Ever had stillbirth, spontaneous miscarriage or termination	0.1	0.1	0.7	-0.8	-0.1	0.1	-0.0	-0.1	0.5	0.0	-0.2	-0.2	-0.8	-0.5	0.5	0.4	0.0	-0.2	-0.2	-0.2	0.1	-0.5
Breast cancer (self-reported)	0.1	0.1	1.1	-0.3	-0.0	-0.6	-0.2	-1.1	0.3	0.2	0.0	0.1	-0.6	-0.3	-0.4	-0.5	-0.2	-0.2	-0.0	0.4	-0.1	0.0
Eye problems/disorders: Glaucoma	0.1	0.1	0.5	-0.1	-0.3	0.3	0.3	-0.5	0.1	0.7	0.4	0.3	-0.2	0.7	0.2	-0.2	0.3	0.3	-0.0	0.6	0.4	-0.2
Medication: Blood pressure	0.1	0.2	0.6	0.7	0.4	0.1	0.1	0.5	0.1	0.5	0.1	0.8	0.7	-0.4	0.3	0.3	0.4	-0.2	-0.1	0.1	-0.0	0.2
Risk taking	0.1	0.2	1.6	0.6	0.3	-0.1	-0.4	0.4	-0.3	-0.4	-0.1	0.3	-0.4	0.0	-0.7	-0.0	-0.2	-0.5	0.3	-1.3	-0.2	0.5
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Hair Pigment	0.0	0.5	3.8	-0.2	1.3	-0.6	-0.1	-0.1	-0.0	0.2	-0.4	2.0	0.1	-0.5	0.7	-0.4	0.4	-1.0	-0.2	-1.1	-0.6	-0.2

Hub : Genes

HACE1

Models

Trait associations