[Hub]/) : Traits : Impedance of leg (right) : →

chr1:752,566-2,544,640

Best TWAS P=1.74e-09 · Best GWAS P=1.35e-10 conditioned to 0.0122

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC35E2 0.35 0.15 enet 24 0.17 1.0e-20 5.7 -5.4 5.9e-08 0.71 0.17 0.83 FALSE
2 GTEx Brain Cerebellar Hemisphere NADK 0.18 0.11 lasso 7 0.09 3.1e-03 5.9 6.0 1.7e-09 -0.84 0.02 0.72 TRUE
3 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 6.3 -6.0 1.9e-09 0.86 0.01 0.74 FALSE
4 GTEx Lung NADK 0.07 0.03 lasso 3 0.02 8.5e-03 -4.1 5.3 1.2e-07 -0.91 0.02 0.93 FALSE
5 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 5.9 5.7 1.1e-08 -0.77 0.04 0.87 FALSE
6 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 5.8 -5.5 2.9e-08 0.78 0.11 0.89 FALSE
7 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 -5.1 -5.2 1.5e-07 0.86 0.05 0.95 FALSE
8 ROSMAP Brain Pre-frontal Cortex MMP23B 0.05 0.04 lasso 2 0.03 1.9e-04 5.6 5.6 2.6e-08 -0.75 0.05 0.93 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC35E2 0.03 0.03 blup 35 0.01 7.0e-02 6.0 5.3 8.6e-08 -0.93 0.01 0.98 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC35E2 0.03 0.00 blup 34 0.01 5.3e-02 5.5 -5.5 4.7e-08 0.81 0.01 0.67 FALSE