TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (right)
:
←
→
chr8:56,282,834-57,683,880
Best TWAS P=2.61e-10 · Best GWAS P=9.99e-14 conditioned to 7.41e-05
56.2M
56.4M
56.6M
56.8M
57M
57.2M
57.4M
57.6M
0
5
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Muscularis
RPS20
0.12
0.04
lasso
6
0.05
7.2e-04
6.2
6.3
2.6e-10
0.81
0.18
0.70
TRUE
2
GTEx
Skin Not Sun Exposed Suprapubic
RPS20
0.18
0.03
enet
12
0.07
1.5e-04
5.9
5.8
7.3e-09
0.80
0.18
0.36
FALSE
4
The Cancer Genome Atlas
Prostate Adenocarcinoma
RPS20
0.04
0.03
lasso
3
0.04
1.3e-04
5.2
5.4
5.1e-08
0.60
0.00
0.96
FALSE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
RPS20
0.33
0.07
enet
8
0.07
1.7e-08
5.2
5.2
2.6e-07
0.52
0.00
0.99
FALSE