[Hub]/) : Traits : Impedance of leg (right) :

chr8:37,329,315-38,989,813

Best TWAS P=5.81e-11 · Best GWAS P=4.9e-11 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DDHD2 0.04 0.04 bslmm 286 0.04 2.0e-05 6.3 6.2 5.6e-10 0.94 0.03 0.97 FALSE
2 GTEx Adrenal Gland DDHD2 0.25 0.21 lasso 2 0.19 1.7e-07 6.5 6.5 7.1e-11 0.99 0.02 0.97 FALSE
3 GTEx Artery Aorta RP11-90P5.2 0.17 0.02 enet 22 0.06 4.6e-04 6.3 -5.2 2.5e-07 -0.56 0.04 0.59 FALSE
4 GTEx Artery Tibial DDHD2 0.07 0.07 lasso 2 0.05 7.3e-05 6.4 6.4 1.2e-10 1.00 0.02 0.98 FALSE
5 GTEx Breast Mammary Tissue RP11-350N15.5 0.08 0.03 enet 12 0.02 1.9e-02 4.3 -6.1 1.4e-09 -0.90 0.02 0.93 FALSE
6 GTEx Breast Mammary Tissue (Female) RP11-350N15.5 0.12 0.10 lasso 2 0.07 3.9e-03 6.5 -6.5 5.8e-11 -0.99 0.02 0.89 TRUE
7 GTEx Colon Sigmoid DDHD2 0.15 0.15 lasso 3 0.12 7.5e-05 6.3 6.3 3.2e-10 0.97 0.04 0.91 FALSE
8 GTEx Esophagus Muscularis DDHD2 0.12 0.13 lasso 2 0.12 5.7e-08 5.7 5.7 1.2e-08 0.95 0.04 0.96 FALSE
9 GTEx Liver DDHD2 0.29 0.01 lasso 5 -0.01 5.4e-01 6.4 6.3 3.4e-10 0.90 0.03 0.69 FALSE
10 GTEx Nerve Tibial DDHD2 0.15 0.16 enet 26 0.16 2.3e-11 6.3 5.5 4.5e-08 0.92 0.04 0.96 FALSE
11 GTEx Pituitary DDHD2 0.25 0.22 lasso 3 0.17 3.9e-05 6.4 5.7 1.2e-08 0.94 0.03 0.92 FALSE
12 GTEx Prostate DDHD2 0.38 0.18 lasso 7 0.17 5.4e-05 5.7 5.8 8.4e-09 0.95 0.10 0.88 FALSE
13 GTEx Spleen DDHD2 0.17 0.17 lasso 2 0.11 7.8e-04 6.5 6.5 7.1e-11 1.00 0.03 0.90 FALSE
14 GTEx Stomach DDHD2 0.13 0.06 lasso 2 0.06 1.1e-03 5.8 5.8 6.7e-09 0.97 0.04 0.88 FALSE
15 GTEx Testis PPAPDC1B 0.11 0.02 lasso 2 0.07 6.6e-04 5.1 5.1 2.8e-07 0.66 0.04 0.43 FALSE
16 GTEx Thyroid DDHD2 0.11 0.10 lasso 4 0.09 3.8e-07 5.7 5.8 5.3e-09 0.95 0.04 0.96 FALSE
17 GTEx Thyroid RP11-90P5.2 0.09 0.00 enet 12 0.01 1.1e-01 6.1 -6.4 1.6e-10 -0.83 0.07 0.72 FALSE
18 NTR Blood BAG4 0.01 0.01 blup 253 0.01 3.9e-03 5.7 -6.1 1.1e-09 -0.95 0.05 0.93 FALSE
19 ROSMAP Brain Pre-frontal Cortex DDHD2 0.05 0.01 lasso 5 0.02 1.6e-03 5.6 5.4 8.4e-08 0.80 0.15 0.73 FALSE
20 ROSMAP Brain Pre-frontal Cortex PPAPDC1B 0.06 0.08 enet 14 0.09 4.0e-11 6.5 6.2 4.3e-10 0.99 0.03 0.97 FALSE
21 ROSMAP Brain Pre-frontal Cortex LSM1 0.09 0.16 lasso 6 0.16 7.3e-20 5.7 -5.8 6.8e-09 -0.96 0.30 0.70 FALSE
22 ROSMAP Brain Pre-frontal Cortex RPS20P22 0.04 0.00 blup 267 0.02 2.9e-03 6.4 6.4 1.7e-10 0.76 0.03 0.86 FALSE
23 YFS Blood BAG4 0.01 0.01 bslmm 234 0.00 2.6e-02 5.3 6.1 1.2e-09 0.84 0.06 0.73 FALSE
24 YFS Blood LSM1 0.02 0.00 bslmm 218 0.01 4.1e-04 4.3 -6.1 1.1e-09 -0.84 0.04 0.94 FALSE
25 The Cancer Genome Atlas Breast Invasive Carcinoma DDHD2 0.01 0.01 blup 21 0.01 2.3e-03 6.4 6.2 4.4e-10 0.98 0.02 0.75 FALSE
26 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BAG4 0.04 0.03 lasso 1 0.02 1.6e-03 5.3 -5.3 1.1e-07 -0.88 0.06 0.39 FALSE
27 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DDHD2 0.03 0.03 blup 21 0.03 3.5e-04 5.6 6.3 3.0e-10 0.99 0.02 0.98 FALSE
28 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PPAPDC1B 0.02 0.00 blup 18 0.01 4.2e-02 6.4 6.3 4.1e-10 0.97 0.01 0.54 FALSE
29 The Cancer Genome Atlas Pancreatic Adenocarcinoma DDHD2 0.07 0.05 blup 21 0.05 2.7e-03 6.3 6.1 1.0e-09 0.98 0.02 0.67 FALSE
30 The Cancer Genome Atlas Prostate Adenocarcinoma DDHD2 0.11 0.08 lasso 3 0.08 1.9e-08 6.3 6.3 3.0e-10 0.97 0.03 0.97 FALSE
31 The Cancer Genome Atlas Thyroid Carcinoma DDHD2 0.02 0.01 blup 21 0.01 2.4e-02 6.5 6.3 3.0e-10 0.99 0.01 0.79 FALSE