[Hub]/) : Traits : Impedance of leg (right) : ← →

chr9:126,844,856-129,961,152

Best TWAS P=4.3e-11 · Best GWAS P=1.52e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	GAPVD1	0.11	0.16	enet	19	0.16	6.4e-13	6.1	6.6	4.3e-11	0.96	0.02	0.98	TRUE
20	GTEx	Whole Blood	MVB12B	0.09	0.04	lasso	4	0.03	7.2e-04	5.2	-5.5	4.7e-08	0.00	0.03	0.87	TRUE
17	GTEx	Thyroid	GAPVD1	0.05	0.05	enet	13	0.01	6.6e-02	6.2	6.5	7.3e-11	0.98	0.02	0.98	FALSE
14	GTEx	Muscle Skeletal	GAPVD1	0.13	0.10	lasso	3	0.09	4.7e-09	6.4	-6.4	1.5e-10	-1.00	0.02	0.98	FALSE
15	GTEx	Nerve Tibial	GAPVD1	0.17	0.08	lasso	10	0.10	9.3e-08	-4.8	6.2	6.3e-10	0.82	0.13	0.87	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	GAPVD1	0.02	0.04	enet	4	0.01	9.8e-03	6.1	-6.2	6.5e-10	-0.94	0.02	0.88	FALSE
12	GTEx	Esophagus Muscularis	OLFML2A	0.08	0.00	enet	27	0.00	4.9e-01	-5.1	-6.0	2.1e-09	-0.46	0.08	0.26	FALSE
7	GTEx	Breast Mammary Tissue (Female)	PPP6C	0.14	0.04	lasso	4	0.04	3.1e-02	-5.3	5.5	3.1e-08	0.69	0.08	0.79	FALSE
11	GTEx	Esophagus Mucosa	PRPS1P2	0.07	0.08	lasso	3	0.07	1.5e-05	-5.3	-5.5	3.5e-08	-0.60	0.48	0.45	FALSE
9	GTEx	Colon Transverse	PRPS1P2	0.11	0.10	lasso	1	0.08	1.8e-04	-5.5	-5.5	3.6e-08	-0.62	0.56	0.16	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPP6C	0.02	0.02	lasso	2	0.01	1.5e-02	-5.5	5.5	4.0e-08	0.62	0.02	0.72	FALSE
5	GTEx	Brain Cerebellum	PRPS1P2	0.09	0.08	enet	16	0.04	2.8e-02	6.4	-5.4	5.7e-08	-0.83	0.05	0.79	FALSE
25	The Cancer Genome Atlas	Stomach Adenocarcinoma	PPP6C	0.05	0.04	blup	46	0.03	3.8e-03	-5.3	5.4	6.3e-08	0.62	0.03	0.95	FALSE
16	GTEx	Pancreas	PRPS1P2	0.16	0.13	lasso	6	0.12	8.7e-06	-5.2	-5.4	6.8e-08	-0.61	0.76	0.20	FALSE
8	GTEx	Cells Transformed fibroblasts	PRPS1P2	0.09	0.11	enet	8	0.13	9.6e-10	-5.5	-5.4	7.5e-08	-0.59	0.80	0.20	FALSE
1	GTEx	Adipose Subcutaneous	PPP6C	0.06	0.10	lasso	3	0.07	3.2e-06	-5.4	5.3	9.0e-08	0.69	0.80	0.19	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP6C	0.02	0.02	lasso	4	0.02	7.6e-04	-5.2	5.3	1.0e-07	0.61	0.02	0.96	FALSE
4	GTEx	Artery Tibial	PRPS1P2	0.06	0.06	enet	6	0.05	9.2e-05	-5.2	-5.3	1.3e-07	-0.60	0.78	0.19	FALSE
19	GTEx	Whole Blood	PPP6C	0.03	0.00	enet	20	0.00	1.0e-01	6.0	5.3	1.4e-07	0.67	0.04	0.86	FALSE
18	GTEx	Thyroid	PRPS1P2	0.08	0.09	enet	18	0.07	4.0e-06	-5.2	-5.2	1.5e-07	-0.67	0.82	0.18	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP6C	0.07	0.08	lasso	3	0.09	5.4e-10	-5.2	5.2	2.0e-07	0.62	0.04	0.96	FALSE
2	GTEx	Artery Aorta	PRPS1P2	0.08	0.10	lasso	4	0.08	2.1e-05	4.3	-5.2	2.2e-07	-0.82	0.06	0.88	FALSE
26	The Cancer Genome Atlas	Thyroid Carcinoma	PPP6C	0.08	0.13	enet	9	0.13	5.5e-13	-5.4	5.2	2.2e-07	0.63	0.02	0.98	FALSE
6	GTEx	Breast Mammary Tissue (Male)	PPP6C	0.12	0.03	enet	12	0.03	6.5e-02	-5.2	5.2	2.4e-07	0.59	0.07	0.11	FALSE
10	GTEx	Esophagus Mucosa	PPP6C	0.07	0.07	enet	21	0.08	7.1e-06	-4.8	5.2	2.5e-07	0.62	0.84	0.15	FALSE
13	GTEx	Esophagus Muscularis	MVB12B	0.24	0.06	enet	15	0.08	1.9e-05	-4.8	-5.1	3.1e-07	0.03	0.08	0.75	FALSE