Best TWAS P=1.65e-09 · Best GWAS P=2.74e-11 conditioned to 0.00387
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | LOXL1-AS1 | 0.28 | 0.09 | lasso | 6 | 0.17 | 1.7e-12 | 3.2 | 5.3 | 9.0e-08 | -0.64 | 0.84 | 0.15 | FALSE |
| 2 | GTEx | Testis | LOXL1-AS1 | 0.36 | 0.15 | lasso | 10 | 0.13 | 2.4e-06 | -5.9 | -6.0 | 1.7e-09 | 0.60 | 0.12 | 0.79 | TRUE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | ISLR | 0.02 | 0.02 | lasso | 2 | 0.01 | 6.2e-04 | -5.1 | 5.2 | 2.1e-07 | -0.15 | 0.01 | 0.95 | TRUE |