TWAS
hub
About
Usage
Models
Genes
Traits
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Traits
:
Impedance of leg (right)
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chr16:55,526,487-57,089,130
Best TWAS P=2.96e-08 · Best GWAS P=1.18e-08 conditioned to 0.0857
55.6M
55.8M
56M
56.2M
56.4M
56.6M
56.8M
57M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Muscle Skeletal
GNAO1
0.06
0.00
lasso
3
0.00
1.1e-01
-5.5
-5.5
3.0e-08
0.88
0.03
0.79
TRUE
1
GTEx
Artery Tibial
GNAO1
0.13
0.12
lasso
4
0.11
6.0e-09
-5.2
5.5
3.3e-08
-0.94
0.02
0.98
FALSE
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
GNAO1
0.06
0.00
blup
103
0.01
2.0e-02
4.2
5.3
1.3e-07
-0.76
0.04
0.68
FALSE