Best TWAS P=2.96e-08 · Best GWAS P=1.18e-08 conditioned to 0.0857
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | GNAO1 | 0.13 | 0.12 | lasso | 4 | 0.11 | 6.0e-09 | -5.2 | 5.5 | 3.3e-08 | -0.94 | 0.02 | 0.98 | FALSE |
| 2 | GTEx | Muscle Skeletal | GNAO1 | 0.06 | 0.00 | lasso | 3 | 0.00 | 1.1e-01 | -5.5 | -5.5 | 3.0e-08 | 0.88 | 0.03 | 0.79 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GNAO1 | 0.06 | 0.00 | blup | 103 | 0.01 | 2.0e-02 | 4.2 | 5.3 | 1.3e-07 | -0.76 | 0.04 | 0.68 | FALSE |