TWAS
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Usage
Models
Genes
Traits
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Traits
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Impedance of leg (right)
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chr20:2,527,510-3,066,362
Best TWAS P=5.84e-08 · Best GWAS P=6.03e-08 conditioned to 0.0513
2.5M
2.6M
2.7M
2.8M
2.9M
3M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
CPXM1
0.03
0.01
lasso
3
0.02
0.0022
3.3
5.4
5.8e-08
-0.77
0.00
0.88
TRUE
1
The Cancer Genome Atlas
Esophageal Carcinoma
FAM113A
0.13
0.05
lasso
6
0.03
0.0324
5.1
-5.3
9.3e-08
0.85
0.01
0.71
FALSE