Hub : Genes

CPXM1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Thyroid 0.2950 0.0720 5.4e-05 0.048 NA 0.064 NA 0.077 1.5e-04 NA 1.2e-05 NA 1.7e-06
2 ROSMAP Brain Pre-frontal Cortex 0.0711 0.0272 7.4e-03 0.037 0.005 0.018 0.03 0.037 1.5e-05 6.0e-02 2.1e-03 8.5e-05 1.5e-05
3 TCGA Breast Invasive Carcinoma 0.0558 0.0189 3.6e-08 0.018 0.033 0.022 NA 0.019 1.1e-04 1.7e-07 1.9e-05 NA 6.6e-05
4 TCGA Brain Lower Grade Glioma 0.0374 0.0196 4.4e-03 0.015 0.009 0.006 NA 0.016 7.5e-03 2.6e-02 5.9e-02 NA 5.6e-03
5 TCGA Lung Squamous Cell Carcinoma 0.0695 0.0222 2.0e-07 0.065 0.072 0.063 NA 0.066 7.1e-08 1.4e-08 1.2e-07 NA 6.0e-08
6 TCGA Ovarian Serous Cystadenocarcinoma 0.1090 0.0460 6.0e-04 0.013 0.060 0.062 NA 0.051 4.0e-02 6.7e-05 4.9e-05 NA 2.4e-04
7 TCGA Prostate Adenocarcinoma 0.0316 0.0174 5.5e-03 0.013 0.021 0.008 NA 0.022 1.6e-02 2.5e-03 3.9e-02 NA 2.2e-03
8 TCGA Thyroid Carcinoma 0.0650 0.0260 5.5e-05 0.044 0.043 0.047 NA 0.050 3.8e-05 4.4e-05 2.3e-05 NA 1.2e-05

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8
Bipolar Disorder (2018) 0.7 1.2 4.3 -0.7 -1.1 -2.1 -0.7 -1.4 -0.4 -0.4 -0.9
Bipolar Disorder or Schizophrenia 0.5 1.2 3.1 -0.7 -1.2 -1.8 -1.0 -1.6 -0.7 0.1 -0.8
Depressed Affect (Nagel 2018) 0.4 0.8 4.4 -0.5 0.5 0.0 0.7 0.2 2.1 0.4 1.1
Depression (Nagel 2018) 0.3 0.5 1.2 -0.2 0.7 1.0 1.0 1.1 0.1 -0.4 -0.2
Intelligence (Savage-Jansen 2018) 0.4 1.3 5.4 0.3 1.0 2.3 0.9 1.2 1.2 -0.0 0.0
Neuroticism (Nagel 2018) 0.6 1.3 4.8 -0.2 1.5 0.8 1.0 1.0 2.2 0.6 0.7
Schizophrenia (2018) 0.2 0.4 0.9 -0.3 -0.7 -0.7 -0.7 -1.0 -0.6 0.5 -0.3
Schizophrenia vs Biploar Disorder 0.6 0.8 2.0 0.6 -0.9 -1.0 -1.4 -0.7 -0.5 1.2 0.3
Worry (Nagel 2018) 0.5 1.0 2.1 0.6 1.4 0.3 0.3 1.0 1.4 1.4 0.8
Alzheimer’s Disease (in mother) 0.5 0.6 1.4 -0.4 1.2 -1.1 1.0 0.5 0.2 -0.8 -0.5
Alzheimer’s Disease (in father) 0.8 0.8 2.5 0.4 0.1 0.1 -0.4 -0.1 1.2 1.6 1.5
Alzheimer’s Disease (including proxy) 0.3 0.5 1.7 0.0 0.9 -1.3 0.1 0.2 0.8 0.2 0.6
Crohns Disease (2017) 0.2 0.5 1.7 -0.1 0.9 0.8 1.3 0.1 0.5 0.1 -0.6
Irritable Bowel Disease (IBD) 0.2 0.5 1.3 0.0 0.5 1.1 1.1 0.3 0.5 0.1 -0.9
Ulcerative Colitis (UC) 0.2 0.4 1.6 0.4 0.3 1.2 0.7 0.5 0.2 0.2 -0.8
Major Depression (MDD) 1.0 1.3 3.4 -0.8 1.8 1.6 1.6 0.4 -0.5 -0.1 -0.6
Reaction Time 0.2 0.4 1.2 -1.0 0.6 0.4 0.6 -0.0 0.2 -1.1 0.1
Verbal and Numeric Reasoning (VNR) 0.1 0.2 0.8 0.2 0.7 0.9 0.6 0.2 -0.1 0.1 -0.3
Breast Cancer 0.8 1.9 5.5 0.3 -1.7 -2.3 -1.8 -1.4 1.0 0.5 0.5
Ovarian Cancer 0.3 0.4 1.2 -0.2 -0.9 -0.6 -1.1 -0.2 0.1 0.2 0.9
Prostate Cancer 1.2 1.7 3.1 -0.2 1.6 1.7 1.8 1.7 1.5 0.1 0.0
Age at First Birth 2.0 2.9 6.7 2.6 0.0 -0.5 -2.1 0.5 0.8 2.6 2.1
Bipolar Disorder (2011) 0.0 0.0 0.2 0.0 -0.5 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.3 0.5 1.8 1.3 -0.1 -0.5 -0.6 0.4 0.5 0.6 0.7
Coronary Artery Disease (CAD) 0.2 0.3 1.9 -0.1 -0.1 -0.0 0.2 -0.5 1.4 -0.1 0.0
Crohns Disease (2012) 0.4 0.7 1.6 0.8 0.9 0.8 1.3 0.3 1.2 0.5 0.5
Mean Putamen Volume 0.2 0.2 0.6 0.6 0.2 -0.4 -0.1 -0.1 -0.7 -0.7 0.5
Fasting Glucose 1.3 1.6 3.8 1.5 -0.9 -0.7 -1.9 -1.5 -1.0 1.1 0.9
HbA1C 0.6 0.7 3.1 1.8 0.3 -0.3 -0.8 1.2 -0.2 0.1 0.6
HDL Cholesterol 0.5 0.8 1.9 -0.8 -1.3 -0.7 -0.7 -1.4 0.4 0.9 0.4
LDL Cholesterol 0.2 0.4 0.7 0.6 0.9 0.8 0.5 0.8 0.1 0.2 0.6
Lupus 0.9 1.3 2.9 -0.0 -1.7 -1.3 -1.4 -1.1 -0.3 1.3 0.8
Neuroticism (2016) 0.8 1.2 3.4 0.4 1.5 0.5 0.7 1.4 1.8 0.8 0.5
Primary Biliary Cirrhosis 0.2 0.3 0.7 0.7 0.5 -0.3 -0.5 0.6 0.6 0.1 0.9
Rheumatoid Arthritis 0.7 1.0 2.4 -0.7 -1.5 -0.9 -1.2 -1.5 -0.4 0.4 -0.3
Schizophrenia (2014) 0.3 0.6 1.6 0.1 -0.6 -1.2 -1.0 -1.0 -0.2 0.9 -0.1
Triglycerides 0.2 0.3 0.8 0.8 0.9 0.7 -0.1 -0.0 -0.1 -0.2 0.6
Type 2 Diabetes (T2D) (2012) 0.2 0.2 0.5 -0.4 0.7 0.3 0.6 -0.1 -0.4 -0.3 -0.1
Ulcerative Colitis 0.4 0.6 1.1 0.3 0.9 0.9 0.9 1.0 0.6 -0.5 -0.8
Blood Eosinophil Count 0.5 4.2 14.9 1.1 2.0 0.5 -0.3 0.9 2.4 3.9 2.6
Blood Platelet Count 0.3 3.1 5.2 0.9 2.3 2.1 1.2 1.1 1.6 2.2 2.1
Blood Red Count 0.0 0.3 0.9 0.4 0.8 0.2 0.0 0.4 1.0 -0.0 0.5
Blood White Count 0.7 5.4 19.1 2.1 1.0 0.7 -1.7 1.2 2.0 4.4 3.2
Heel T-Score 0.3 2.1 3.9 -1.3 1.6 1.6 2.0 0.7 1.7 -1.5 -0.5
BMI 1.9 11.2 31.4 -3.5 -1.8 -2.1 1.4 -2.1 -3.8 -5.6 -4.1
Height 0.1 1.5 5.9 0.5 -0.6 2.4 -0.4 2.1 0.7 0.4 0.6
Waist Hip Ratio (WHR) 0.5 2.1 6.2 1.3 1.3 0.7 -0.4 2.5 1.8 1.4 1.2
Systolic Blood Pressure 2.0 10.2 20.4 1.8 -1.8 -2.0 -4.2 -0.8 3.6 4.5 4.4
Smoking Status 0.8 2.0 5.9 0.7 0.1 -2.0 -1.3 -1.6 -2.4 -0.8 0.4
Allergy or Eczema 0.4 1.1 2.7 -0.6 0.9 0.4 1.5 0.5 -1.0 -1.1 -1.6
Cardiovascular Disease 0.1 0.4 1.9 0.7 0.7 -0.1 -0.2 1.4 0.2 -0.4 0.6
Hypothyroidism (self reported) 0.1 0.2 0.5 0.1 -0.2 0.7 -0.0 -0.0 -0.7 0.7 0.4
Respiratory disease 1.4 3.1 13.8 -0.6 0.9 -1.0 0.7 -1.3 -3.7 -2.0 -1.7
Type 2 Diabetes (T2D) (2018) 1.2 2.3 5.1 -0.9 0.9 2.0 2.3 1.6 -0.0 -1.9 -1.1
Lung FEV1/FVC ratio 0.4 1.9 4.8 0.9 1.3 2.1 1.6 2.2 -0.2 -0.9 -0.5
Lung FVC 0.3 1.5 4.1 0.1 2.0 1.1 1.5 1.7 0.5 -1.0 -0.1
Neuroticism 0.8 1.9 8.2 0.1 1.4 0.7 0.7 0.4 2.9 1.6 1.3
Chronotype (morning person) 0.7 1.6 4.9 0.4 -0.0 -0.9 -1.1 -0.7 1.6 2.2 1.7
Hair Pigment 0.0 0.2 0.6 -0.5 0.2 -0.3 0.4 0.6 0.1 -0.4 -0.8
Tanning 0.1 1.0 2.2 -0.9 1.2 0.5 1.2 0.7 -1.0 -1.5 -0.5
Hand grip strength (left) 0.6 1.7 4.9 0.6 2.2 2.0 1.3 1.0 0.7 0.3 1.1
Number of treatments/medications taken 0.3 0.6 1.1 -0.8 0.7 0.7 0.7 1.0 0.1 -1.1 0.2
Average weekly spirits intake 0.5 0.6 1.7 0.0 -0.2 1.0 0.7 1.3 0.3 -1.2 -0.5
Sensitivity / hurt feelings 0.4 0.7 1.8 -1.3 0.3 0.6 1.1 -0.4 0.9 -1.1 -0.6
Frequency of depressed mood in last 2 weeks 0.6 0.8 2.0 0.2 1.4 1.2 0.7 0.6 1.0 0.6 0.7
Hearing difficulty/problems: Yes 0.3 0.5 1.6 0.0 0.3 0.9 0.6 0.8 1.3 -0.5 0.3
Relative age of first facial hair 0.9 1.8 3.5 -0.3 1.7 0.9 0.7 1.2 1.9 1.8 1.3
Other serious medical condition/disability diagnosed by doctor 0.8 1.0 2.2 -1.4 0.3 1.2 1.5 0.8 0.4 -0.5 -1.0
Ever used hormone-replacement therapy (HRT) 1.5 1.9 7.6 -0.7 -0.4 0.3 0.7 0.5 -1.8 -2.7 -1.7
Ever had hysterectomy (womb removed) 1.3 1.5 2.8 1.2 0.9 1.7 1.5 1.5 0.2 -1.4 -0.4
Systolic blood pressure, automated reading 2.8 8.3 21.4 0.5 -3.6 -3.4 -4.6 -2.1 0.6 3.0 2.4
Eye problems/disorders: Diabetes related eye disease 0.2 0.2 0.8 -0.1 -0.1 -0.3 0.2 0.1 -0.5 -0.9 -0.4
Angina 0.9 1.1 3.7 0.3 -1.9 -1.2 -1.6 -0.7 0.1 0.4 0.7
Medication for hormone replacement therapy 1.6 1.8 4.1 1.0 2.0 1.4 1.4 1.6 0.6 -1.3 0.7
Vitamin and mineral supplements 1.3 1.8 5.8 0.5 1.0 -0.5 -0.4 0.3 2.4 1.4 2.1
Supplements: Zinc 2.5 2.7 6.3 -1.6 -0.6 0.7 0.9 -0.2 -2.5 -2.5 -2.3
Medication: Co-codamol 0.6 0.7 1.6 0.9 -1.2 -1.1 -1.3 -0.1 0.1 -0.1 0.6
Medication: Metformin 1.4 2.0 4.1 -0.1 1.6 1.6 1.3 2.0 1.9 0.1 1.0
Diabetes (father) 0.2 0.2 0.8 0.4 0.5 -0.4 0.1 0.4 -0.3 -0.9 -0.3
Diabetes (mother) 0.2 0.2 0.6 -0.1 -0.1 -0.8 0.0 -0.7 -0.1 -0.7 -0.3
Severe depression (siblings) 1.5 1.7 3.7 0.9 1.4 0.3 -0.1 0.9 1.8 1.9 1.9
Pack years adult smoking proportion 0.4 0.6 1.5 1.2 -0.4 -0.4 -0.9 1.2 -0.2 -0.6 0.3
Impedance of leg (right) 1.8 8.8 29.4 3.4 1.4 1.5 -1.0 2.1 3.0 5.4 3.3
Leg fat-free mass (left) 0.6 3.3 14.1 -1.8 -0.5 0.5 1.2 -0.0 -1.8 -3.8 -2.0
Trunk fat percentage 0.5 1.9 4.9 -1.4 -0.7 -0.2 1.0 -0.0 -2.2 -2.2 -1.4
Hand grip strength (right) 0.8 2.3 8.5 0.5 1.8 2.9 1.6 1.6 0.7 -0.1 0.7
Townsend deprivation index at recruitment 1.8 2.5 8.4 -1.3 -1.5 -1.8 -0.9 -2.9 -1.4 -1.0 -0.9
Current tobacco smoking 0.8 1.3 3.3 0.8 -0.8 -1.3 -1.6 -1.3 -1.8 -0.4 0.1
Average weekly fortified wine intake 1.2 1.4 2.9 0.5 1.5 1.2 1.2 1.7 -0.5 -1.5 -0.3
Maternal smoking around birth 1.1 1.5 4.5 -1.6 0.0 -0.6 1.0 -0.6 -0.7 -2.1 -1.7
Fed-up feelings 0.1 0.3 1.0 0.3 0.3 0.1 0.5 -0.3 0.8 0.2 1.0
Frequency of unenthusiasm / disinterest in last 2 weeks 0.2 0.3 0.6 0.2 0.7 0.8 0.8 0.2 0.1 -0.7 0.2
Relative age voice broke 0.3 0.5 1.7 0.7 0.9 0.1 -0.1 1.3 0.4 0.7 0.6
Taking other prescription medications 0.1 0.2 0.7 -0.5 0.6 -0.6 -0.1 0.2 0.1 0.1 0.8
Age when periods started (menarche) 0.1 0.3 0.9 1.0 0.2 0.7 -0.3 0.7 -0.6 0.4 -0.2
Bilateral oophorectomy (both ovaries removed) 1.0 1.1 4.7 0.2 -0.0 1.2 0.9 1.1 0.1 -2.2 -0.9
Heel bone mineral density (BMD) T-score, automated (left) 1.1 2.6 8.6 -2.2 -0.3 0.5 1.4 -0.6 -0.6 -2.9 -2.1
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 0.9 0.4 -0.9 -0.6 -0.8 -0.9 -0.4 0.4 -0.2
Qualifications: CSEs or equivalent 0.8 1.1 3.1 -0.5 -1.6 -1.8 -0.8 -1.5 -0.1 0.1 0.1
Serious illness, injury or assault to yourself 0.2 0.2 0.5 0.5 -0.6 -0.7 -0.4 0.2 -0.2 -0.6 0.1
High blood pressure 0.2 0.7 2.1 0.3 -0.8 -0.1 -1.4 1.0 0.0 0.4 1.1
Hayfever, allergic rhinitis or eczema 1.1 2.3 5.9 -0.7 1.7 1.5 2.4 1.1 -0.7 -1.2 -2.0
Multivitamins +/- minerals 1.2 1.6 7.0 0.1 -0.5 -0.1 0.4 -0.5 -2.6 -1.3 -1.8
Stomach or abdominal pain in last month 1.9 2.4 4.5 -2.0 0.6 0.3 1.7 -0.7 -1.7 -2.1 -2.0
Supplements: Glucosamine 1.1 1.4 4.3 0.1 -2.1 -0.2 -0.5 -0.8 -1.6 -1.3 -1.4
Diverticular disease/diverticulitis (self-reported) 1.0 1.2 2.6 -1.6 -0.3 -0.1 0.7 -1.0 -1.5 -0.8 -1.6
Medication: Atenolol 0.7 0.8 2.6 0.1 1.1 1.1 0.9 1.6 0.7 -0.2 0.6
Medication: Levothyroxine sodium 0.6 1.0 3.0 -0.5 0.9 1.7 1.3 0.9 0.8 0.9 0.0
Sitting height 0.1 0.9 2.9 1.4 0.0 0.6 -0.8 0.2 0.6 1.7 0.9
Chronic bronchitis/emphysema (father) 0.4 0.5 1.0 0.9 -1.0 -0.9 -0.7 -0.1 -0.6 -0.5 -0.5
High blood pressure (mother) 0.2 0.3 0.8 0.4 0.1 -0.6 -0.5 -0.1 0.7 0.1 0.9
Body mass index (BMI) 1.1 4.5 12.9 -2.7 -0.5 -0.9 1.7 -0.8 -2.4 -3.6 -2.4
Impedance of leg (left) 1.7 8.3 27.8 3.3 1.0 1.3 -1.0 1.8 3.2 5.3 3.2
Leg predicted mass (left) 0.6 3.4 14.4 -1.8 -0.6 0.4 1.1 -0.1 -1.9 -3.8 -2.1
Trunk fat mass 0.5 2.2 6.7 -1.6 -0.6 0.2 1.2 0.2 -2.0 -2.6 -1.6
Waist circumference 0.7 2.6 7.7 -2.2 -0.6 -0.5 1.0 -0.4 -1.9 -2.8 -1.9
Number of incorrect matches in round 1.3 2.2 5.3 -1.9 -1.5 -1.4 -0.0 -1.1 -1.1 -1.5 -2.3
Past tobacco smoking 0.3 0.5 1.2 -0.9 -1.1 0.5 0.3 0.5 0.8 -0.4 -1.0
Alcohol usually taken with meals 0.4 0.6 1.4 0.8 -0.9 0.8 -0.0 0.7 -0.7 -0.9 -1.2
Nervous feelings 0.9 1.8 5.5 0.5 1.8 0.6 0.6 1.4 2.3 1.4 0.7
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 0.7 0.5 0.8 0.3 0.2 -0.2 -0.2 0.3 -0.0
Hearing difficulty/problems with background noise 0.5 0.8 1.7 0.8 1.2 1.0 0.3 1.3 0.7 0.2 1.1
Hair/balding pattern: Pattern 2 1.0 1.3 3.3 -1.8 -0.7 -0.3 0.3 -1.8 -1.2 -0.7 -1.1
Had menopause 1.1 1.4 4.1 -0.2 -1.8 -2.0 -1.4 -1.1 -0.7 -0.4 -0.2
Had other major operations 2.1 2.5 5.6 -2.4 -1.0 -0.6 1.3 -1.5 -1.3 -1.5 -2.4
Forced vital capacity (FVC) 0.5 1.8 4.8 0.7 1.8 2.2 1.1 1.2 1.4 0.7 0.9
Heel bone mineral density (BMD) T-score, automated (right) 0.9 2.0 4.9 -1.9 -1.0 -0.4 0.6 -1.5 -0.7 -2.2 -1.7
Ever unenthusiastic/disinterested for a whole week 0.7 0.8 2.6 -0.8 1.0 1.0 0.7 -0.1 -1.6 -0.8 -0.4
Qualifications: None of the above 1.1 2.3 9.1 0.5 -1.1 -3.0 -2.1 -1.5 -0.7 0.3 0.8
Financial difficulties in last 2 years 0.1 0.1 0.2 -0.5 0.2 0.3 0.3 -0.3 -0.2 0.2 0.3
Mouth/teeth dental problems 0.9 1.4 5.3 0.3 0.5 1.5 0.6 1.1 2.3 1.0 0.8
Heart attack 0.4 0.5 1.7 1.3 -0.9 -0.2 -0.8 0.5 0.3 0.4 0.4
Allergy 1.1 2.6 7.7 1.1 -0.4 -0.3 -1.3 0.0 2.8 2.2 2.3
Pain all over the body in last month 1.2 1.3 4.8 1.1 -1.0 -2.2 -1.6 -0.3 -0.3 0.5 0.7
Diabetes (self-reported) 0.3 0.4 1.5 0.1 0.2 0.9 0.6 1.2 0.4 -0.4 0.4
Hayfever/allergic rhinitis (self-reported) 1.0 1.3 3.1 -0.1 -1.0 -1.4 -1.2 -1.6 0.2 1.8 0.8
Medication: Ramipril 1.6 2.1 4.0 2.0 -0.5 -0.4 -1.9 1.6 1.5 0.8 1.8
Medication: Simvastatin 1.4 2.1 3.9 0.0 2.0 1.9 1.7 2.0 1.4 -0.6 0.4
Fluid intelligence score 0.2 0.3 1.1 0.6 0.3 0.1 -0.5 -0.7 0.2 1.1 0.6
Illnesses of siblings 0.3 0.4 1.3 -0.2 -0.5 -0.8 -0.5 -0.9 0.1 1.1 -0.4
Neuroticism score 1.3 2.8 9.1 -0.0 2.1 1.7 1.7 0.9 3.0 1.0 1.0
Weight 0.5 2.7 8.2 -2.0 -0.3 0.4 1.5 0.0 -1.7 -2.9 -1.9
Impedance of arm (right) 0.5 2.1 7.9 1.9 -0.2 0.5 -1.1 0.9 1.3 2.8 1.2
Arm fat percentage (right) 0.9 3.6 9.4 -2.0 -0.4 -0.4 1.6 -0.3 -2.6 -3.1 -2.3
Trunk fat-free mass 0.3 1.9 4.5 -1.3 0.7 1.7 1.6 1.1 -0.3 -2.1 -1.2
Hip circumference 1.1 4.7 10.2 -2.5 -1.4 -0.7 1.0 -1.5 -2.8 -3.2 -2.7
Time employed in main current job 0.7 0.8 2.1 0.1 0.5 1.0 0.3 1.4 1.4 1.1 0.4
Alcohol intake versus 10 years previously 0.3 0.4 1.7 -0.6 -0.3 -0.4 0.1 -0.1 -0.9 -1.3 -0.4
Father’s age at death 1.0 1.4 4.1 0.2 1.0 2.0 1.5 1.1 1.5 0.2 0.2
Worrier / anxious feelings 0.2 0.4 1.0 -0.1 0.9 0.5 0.5 0.4 1.0 0.7 0.4
Frequency of tiredness / lethargy in last 2 weeks 0.5 0.7 2.3 -0.5 1.2 0.7 1.5 0.3 0.9 -0.8 -0.0
Falls in the last year 0.3 0.4 1.1 -0.4 -0.2 0.5 0.7 0.8 1.1 -0.6 -0.3
Hair/balding pattern: Pattern 3 0.5 0.8 1.9 1.3 0.4 0.6 -0.4 1.4 0.7 0.6 1.0
Number of live births 1.0 1.4 3.9 -1.2 -1.0 -1.5 -0.3 -2.0 -1.5 -0.6 -0.6
Forced expiratory volume in 1-second (FEV1) 1.2 4.1 10.6 0.9 2.6 3.3 2.0 2.4 2.0 0.5 0.6
Pulse rate 1.1 1.9 4.9 0.9 -1.8 -2.2 -1.5 -0.6 -1.7 -0.9 -0.3
Happiness 0.5 0.6 1.9 -1.4 -1.0 0.0 0.0 -1.1 -0.1 0.4 -0.5
Noisy workplace 0.6 0.7 2.0 0.2 -1.1 -1.4 -1.4 -0.5 0.1 -0.0 -0.4
Qualifications: A levels/AS levels or equivalent 0.2 0.5 1.2 -0.9 0.4 0.7 1.1 0.1 -0.4 0.1 -0.9
Serious illness, injury or assault of a close relative in last 2 years 0.3 0.3 1.3 -0.0 -0.4 0.5 0.7 0.2 1.1 0.3 -0.7
Mouth/teeth dental problems: Dentures 0.7 1.1 3.5 0.1 -1.1 -1.9 -1.5 -0.9 -0.9 0.2 0.4
Asthma 1.7 3.4 17.0 -0.5 -0.4 -1.1 -0.2 -1.5 -4.1 -1.8 -1.8
Medication: Ibuprofen (e.g. Nurofen) 0.6 0.8 1.7 -0.9 -0.6 -0.2 0.5 -1.2 -1.0 -0.9 -1.3
Medication: Cholesterol lowering 0.6 1.0 3.6 0.6 0.7 0.9 0.3 1.9 1.1 -0.6 0.9
Depression (self-reported) 1.8 2.1 6.1 -1.0 1.5 2.5 2.0 1.2 0.9 -1.1 0.1
Medication: Lansoprazole 0.8 1.0 1.6 1.3 -0.6 0.4 -0.8 1.2 1.2 0.7 1.2
Prospective memory result 1.3 1.6 6.0 0.8 0.9 2.1 0.7 2.5 0.9 -0.5 -0.0
Lung cancer (father) 2.3 2.7 5.3 1.1 -1.3 -2.0 -2.3 -1.0 0.9 1.9 1.9
Illnesses of mother 0.3 0.4 1.3 0.0 -0.6 0.7 0.3 -0.4 -1.2 0.3 -0.7
Forced expiratory volume in 1-second (FEV1), Best measure 1.3 4.0 10.1 0.6 2.5 3.2 2.0 2.2 2.5 0.3 0.6
Pulse wave Arterial Stiffness index 2.2 2.5 8.4 1.9 -0.0 -0.2 -1.2 0.1 1.5 2.9 2.1
Impedance of arm (left) 0.4 1.7 5.7 1.8 -0.9 -0.4 -1.6 -0.1 0.3 2.4 1.0
Arm fat mass (right) 1.0 4.2 12.9 -2.3 -0.2 -0.1 1.8 -0.0 -2.5 -3.6 -2.4
Trunk predicted mass 0.3 1.7 4.2 -1.2 0.7 1.7 1.6 1.1 -0.2 -2.0 -1.1
Standing height 0.2 2.3 9.0 1.3 0.4 3.0 0.0 2.1 1.3 1.2 0.8
Length of working week for main job 1.3 1.5 3.2 -0.5 1.2 1.5 1.8 1.1 -0.8 -1.3 -1.0
Exposure to tobacco smoke at home 0.9 1.1 2.5 -1.4 1.1 0.4 1.6 -0.1 -0.4 -0.8 -1.3
Breastfed as a baby 0.8 0.9 2.6 -0.7 0.5 0.4 1.2 0.9 -0.6 -1.6 -1.2
Tense / ‘highly strung’ 2.0 3.3 6.1 2.4 1.9 0.5 -0.3 1.2 2.5 2.2 2.0
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.0 -0.9 1.0 0.5 0.3 -0.3 -0.8 0.6 0.3
Hair/balding pattern: Pattern 4 0.4 0.9 2.4 -0.5 0.1 -0.3 0.9 -0.4 -1.4 -1.5 -1.3
Birth weight of first child 2.5 4.5 14.4 -1.5 1.7 3.8 3.2 1.4 0.7 -1.4 -1.3
Peak expiratory flow (PEF) 1.9 4.4 10.3 1.5 2.2 2.3 0.8 2.0 3.2 2.3 1.7
Pulse wave reflection index 4.8 5.9 12.2 2.3 2.4 1.5 -0.1 1.7 2.9 3.5 3.3
Ever highly irritable/argumentative for 2 days 0.3 0.4 2.3 -0.3 0.2 -0.1 -0.2 -0.5 -1.5 -0.4 -0.6
Loud music exposure frequency 1.3 1.4 3.5 0.9 1.4 0.8 0.2 1.2 1.6 0.8 1.9
Qualifications: O levels/GCSEs or equivalent 0.3 0.4 1.3 0.4 0.8 1.2 1.0 0.2 -0.1 -0.2 -0.3
Mouth/teeth dental problems: Bleeding gums 2.1 2.7 5.6 -1.9 0.8 0.5 1.8 0.0 -1.9 -2.4 -2.1
Blood clot in the leg (DVT) 1.2 1.6 3.8 -1.1 -1.5 -0.1 -0.2 -0.3 -1.9 -1.9 -1.2
Medication: Paracetamol 0.4 0.6 1.5 -0.5 0.6 -1.2 0.2 -0.5 -0.9 -1.2 -0.2
Headache pain in last month 1.9 3.3 7.0 0.7 2.6 2.6 2.5 2.2 0.6 -0.5 -0.5
Medication for cholesterol, blood pressure or diabetes 0.6 0.9 2.7 -0.3 -0.2 -0.2 0.4 -1.6 -1.4 -0.2 -1.6
Glaucoma (self-reported) 1.5 1.8 5.7 -1.3 -2.4 -0.9 -0.9 -1.9 -1.1 -0.1 -0.6
Gout (self-reported) 0.2 0.3 1.0 0.9 0.3 -1.0 -0.4 -0.5 -0.1 0.0 0.6
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 2.0 -0.6 0.5 1.4 0.9 0.5 -0.3 0.7 -0.1
Medication: Amlodipine 0.3 0.4 1.0 -0.0 0.9 0.3 0.1 0.2 0.7 0.8 1.0
Medication: Ventolin 100micrograms inhaler 0.4 0.5 2.3 -0.0 0.1 -0.7 -0.4 -0.8 -1.5 -0.1 -0.3
Birth weight 1.2 2.7 6.3 0.0 1.4 2.0 2.5 0.6 -1.5 -1.7 -1.9
Chronic bronchitis/emphysema (mother) 2.1 2.5 5.9 -1.3 0.1 0.4 1.7 -0.8 -1.8 -2.3 -2.4
High blood pressure (siblings) 0.2 0.3 1.1 -0.0 -0.3 1.1 0.1 0.8 0.0 -0.8 -0.1
Forced vital capacity (FVC), Best measure 0.6 2.3 5.7 0.7 1.6 2.3 1.0 1.2 2.4 0.9 1.1
Body fat percentage 0.4 1.6 4.2 -1.3 -0.4 -0.1 1.2 0.1 -1.9 -2.1 -1.3
Leg fat percentage (right) 0.2 0.6 1.7 -0.9 -0.1 -0.2 0.8 0.3 -1.3 -1.1 -0.7
Arm fat-free mass (right) 0.3 1.4 6.1 -1.0 0.3 0.9 1.2 0.5 -0.9 -2.5 -1.0
Exposure to tobacco smoke outside home 0.3 0.5 1.2 -0.5 -0.9 -0.5 -0.6 -0.5 1.1 0.4 0.5
Comparative body size at age 10 0.2 0.6 1.7 -0.7 -0.8 -0.3 -0.0 -1.3 -1.0 -0.8 -0.4
Number of full brothers 1.0 1.3 5.6 0.7 0.5 1.5 0.6 2.4 0.8 -0.7 0.3
Worry too long after embarrassment 1.9 3.2 9.2 1.0 2.3 3.0 1.8 2.2 1.4 -0.3 0.3
Seen a psychiatrist for nerves, anxiety, tension or depression 0.3 0.4 1.0 -1.0 0.9 0.5 0.6 -0.5 0.2 0.1 -0.2
Wheeze or whistling in the chest in last year 0.9 1.7 3.6 -0.8 0.0 -1.6 0.0 -1.4 -1.9 -1.5 -1.4
Number of children fathered 1.4 1.6 3.5 -1.6 -0.6 0.3 0.9 -0.5 -1.6 -1.7 -1.9
Reason for reducing amount of alcohol drunk: Health precaution 1.7 2.0 5.0 -1.5 -1.0 -1.7 -0.5 -2.2 -1.4 -0.7 -1.4
Age at first live birth 1.8 3.2 7.1 2.1 0.7 0.7 -0.7 2.0 2.7 2.3 1.9
Pulse wave peak to peak time 2.2 2.6 8.6 -1.8 0.1 0.5 1.3 0.2 -1.5 -2.9 -2.2
Health satisfaction 1.2 1.6 3.8 -1.1 -0.9 -0.1 0.5 -1.5 -1.9 -1.7 -1.3
Shortness of breath walking on level ground 0.4 0.4 2.6 0.5 -0.2 -0.4 -0.6 -0.2 -1.6 -0.0 0.1
Qualifications: College or University degree 0.8 2.4 7.9 0.8 1.8 2.8 1.6 1.9 -0.7 0.7 -0.7
Eye problems/disorders: None of the above 1.4 1.6 5.0 0.5 2.2 1.5 1.6 1.4 0.4 -0.7 0.6
Mouth/teeth dental problems: Loose teeth 1.8 2.1 5.5 1.9 -0.8 -2.1 -2.4 -0.6 -0.1 0.3 1.5
Emphysema/chronic bronchitis 1.5 1.7 5.0 -2.2 -0.6 -0.0 0.6 -1.0 -1.6 -1.6 -1.4
Medication for pain relief, constipation, heartburn 0.6 1.0 3.2 1.3 0.3 0.2 -0.8 0.1 0.7 1.8 1.3
Neck or shoulder pain in last month 0.6 0.9 3.0 1.7 0.3 -0.6 -0.8 -0.1 1.0 1.1 1.1
Medication: Blood pressure 0.6 1.1 4.4 0.1 0.3 -0.7 -0.8 0.8 1.3 0.9 2.1
Angina (self-reported) 0.6 0.8 2.4 0.3 -1.6 -1.0 -1.4 -0.6 0.1 0.4 0.8
Migraine (self-reported) 1.1 1.4 5.7 0.7 0.8 2.4 0.5 2.0 0.1 -0.5 0.1
Medication: Ibuprofen 0.4 0.5 2.0 -0.7 -0.7 -0.3 0.0 -1.4 -0.8 -0.2 -0.6
Medication: Allopurinol 0.2 0.2 0.5 0.2 0.4 -0.6 -0.1 -0.6 0.1 0.4 0.7
Medication: Omeprazole 1.4 1.7 4.3 -2.1 -1.2 -0.5 0.2 -1.3 -1.1 -1.3 -1.7
Medication: Seretide 50 evohaler 0.6 0.6 1.7 -0.7 -0.9 -0.5 -0.6 -0.8 -1.3 -0.5 -0.9
Mean time to correctly identify matches 0.4 0.9 2.1 -1.1 0.7 1.4 1.0 0.6 -0.1 -1.3 -0.0
Heart disease (mother) 0.2 0.3 1.1 -0.2 0.2 1.0 -0.1 0.9 0.5 -0.2 0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria 1.8 2.2 5.5 2.3 0.3 0.4 -1.3 0.7 1.3 1.9 2.1
Whole body fat mass 0.6 2.4 7.8 -1.5 -0.4 0.2 1.3 0.4 -2.0 -2.8 -1.7
Leg fat mass (right) 0.5 1.9 6.4 -1.4 -0.6 -0.1 1.1 0.2 -1.7 -2.5 -1.5
Arm predicted mass (right) 0.3 1.6 6.1 -1.2 0.4 1.1 1.3 0.5 -0.9 -2.5 -1.1
Pulse rate, automated reading 0.2 0.5 2.4 1.1 -0.1 -0.5 -0.1 -0.1 -1.5 -0.6 -0.3
Alcohol intake frequency. 0.3 0.7 2.8 -0.7 -0.3 0.1 0.3 -0.4 -1.2 -1.7 -0.6
Comparative height size at age 10 0.1 0.3 0.8 0.6 -0.4 0.8 -0.4 0.3 0.9 -0.5 -0.1
Number of full sisters 0.5 0.6 2.0 -0.6 -0.1 -1.2 -0.5 -1.4 -0.2 -0.6 -0.4
Suffer from ‘nerves’ 0.4 0.6 1.6 -0.1 1.1 0.9 0.4 0.4 1.2 0.9 0.4
Overall health rating 0.4 0.9 2.0 -1.0 -0.5 -1.2 0.2 -1.4 -0.6 -1.1 -0.7
Chest pain or discomfort 0.6 0.8 2.7 0.5 -0.9 -1.6 -1.0 -0.6 -0.9 -0.6 0.3
Had major operations 0.2 0.2 0.5 -0.3 -0.5 0.7 0.4 -0.4 -0.2 -0.2 -0.4
Age at last live birth 1.5 2.2 4.1 1.9 0.7 -0.1 -0.9 1.2 2.0 2.0 1.8
Family relationship satisfaction 1.0 1.2 4.5 -0.2 -0.3 -0.8 -1.3 -1.2 0.6 2.1 1.1
Leg pain on walking 0.0 0.1 0.2 -0.0 0.4 -0.5 0.2 -0.2 -0.0 -0.0 0.0
Qualifications: NVQ or HND or HNC or equivalent 0.3 0.4 1.5 -0.6 0.4 -0.3 0.8 -0.5 0.2 -1.2 -0.4
Commuting to job workplace: Car/motor vehicle 0.6 0.7 1.7 -1.3 -0.1 -0.6 1.2 0.2 0.5 -1.0 -0.8
Illness, injury, bereavement, stress in last 2 years 0.5 0.6 2.4 -0.8 -0.6 -0.9 -0.6 -1.5 -0.2 0.6 0.0
Medication: Aspirin 0.5 0.6 3.1 0.1 -0.1 0.3 -0.1 1.3 1.8 0.1 0.3
Supplements: Vitamin C 1.8 2.1 6.2 -1.2 -0.7 0.1 0.8 -0.8 -2.1 -1.8 -2.5
Knee pain experienced in last month 0.3 0.5 2.5 0.4 -0.5 -1.6 -0.4 -0.4 0.4 -0.7 -0.3
Hypertension (Self-reported) 0.2 0.6 1.7 0.2 -0.4 0.1 -1.2 1.3 0.3 0.1 1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.2 0.2 0.4 -0.6 -0.6 -0.3 0.2 -0.2 -0.3 -0.7 -0.7
Illnesses of father: Heart disease 0.2 0.3 0.7 -0.4 -0.6 -0.8 -0.4 -0.7 0.2 0.6 0.3
Illnesses of siblings: Diabetes 0.1 0.2 0.5 0.2 0.1 -0.7 -0.2 0.5 0.0 -0.5 0.4
Smoking status: Previous 0.2 0.3 0.6 0.4 0.7 -0.8 -0.1 -0.6 -0.5 0.4 0.6
Forced expiratory volume in 1-second (FEV1), predicted 0.6 1.3 4.2 0.9 0.6 1.8 0.7 0.7 2.1 0.8 0.6
Whole body fat-free mass 0.4 2.3 8.6 -1.5 0.3 1.2 1.5 0.7 -1.0 -2.9 -1.5
Leg fat-free mass (right) 0.7 3.8 15.8 -2.0 -0.7 0.4 1.2 -0.3 -1.9 -4.0 -2.2
Arm fat percentage (left) 1.1 4.2 10.8 -2.2 -0.7 -1.0 1.4 -0.8 -2.9 -3.3 -2.4
Average weekly red wine intake 0.4 0.6 1.9 -0.4 -1.4 -0.1 -0.2 -0.5 -0.2 -0.6 -1.4
Handedness (chirality/laterality): Left-handed 0.7 0.9 2.1 -1.5 -0.3 -1.4 0.0 -1.3 0.9 0.5 0.1
Mood swings 0.6 1.1 4.0 0.2 1.0 0.9 1.5 0.8 2.0 -0.2 0.4
Loneliness, isolation 0.7 0.9 3.3 -1.8 0.6 -0.6 0.7 -1.3 0.3 -1.1 -0.1
Long-standing illness, disability or infirmity 0.1 0.2 0.5 -0.2 0.2 -0.0 0.4 -0.6 0.6 -0.0 0.7
Ever had bowel cancer screening 2.3 2.7 6.2 0.9 2.0 2.5 2.0 2.1 1.5 0.0 0.5
Diabetes diagnosed by doctor 0.8 1.4 3.3 -0.8 0.8 1.6 1.8 1.4 -0.0 -1.4 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 1.6 1.7 3.4 -1.9 1.3 -0.5 1.4 -0.9 -1.6 -1.1 -1.5
Friendships satisfaction 1.0 1.2 3.8 -0.1 1.7 1.9 1.3 1.1 -0.0 0.1 -0.3
Qualifications: nursing, teaching 2.5 3.9 7.6 -2.7 0.5 1.4 2.3 1.1 -1.2 -2.4 -2.8
Commuting to job workplace: Walk 0.1 0.1 0.3 0.5 0.5 0.2 -0.0 0.4 -0.0 -0.3 0.0
Eye problems/disorders: Cataract 2.3 2.7 7.1 1.3 -1.6 -1.9 -2.7 -1.2 -0.7 1.9 1.1
Mouth/teeth dental problems: Mouth ulcers 1.0 1.7 4.8 -0.9 -0.2 -0.6 0.4 -0.7 -1.9 -2.2 -1.8
Medication for cholesterol 1.7 2.6 6.0 -1.9 -1.4 -1.5 -0.1 -2.4 -2.0 -0.5 -1.6
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 1.0 2.3 -1.1 0.8 1.2 1.5 1.2 0.6 -0.7 -0.4
Back pain experienced in last month 0.7 1.0 3.5 0.7 -1.1 -1.9 -1.0 -1.2 0.3 -0.6 0.4
Mineral and other dietary supplements 0.9 1.2 3.5 0.7 1.9 0.8 0.2 0.9 1.1 0.9 1.5
Breast cancer (self-reported) 0.4 0.5 1.7 0.3 1.0 0.3 1.3 0.2 0.3 -0.7 -0.2
Asthma (self-reported) 1.8 3.6 19.2 -0.6 -0.1 -0.9 -0.1 -1.4 -4.4 -1.8 -1.9
Osteoporosis (self-reported) 0.9 1.1 2.9 -0.8 1.0 1.7 1.2 1.5 0.4 -0.3 -0.5
Osteoarthritis (self-reported) 0.8 1.0 2.4 1.1 -0.7 -0.4 -1.0 0.1 0.8 1.6 1.3
Medication: Aspirin 0.7 0.9 4.5 -0.0 0.1 0.5 -0.0 1.4 2.1 0.5 0.7
Medication: Gliclazide 0.3 0.3 0.7 0.4 -0.1 0.5 -0.2 0.8 0.6 -0.6 0.8
Illnesses of father: None of the above (group 1) 0.6 0.8 3.0 -0.6 0.3 -0.2 0.5 -0.6 -1.7 -1.1 -1.1
Smoking status: Current 0.8 1.3 3.4 0.7 -0.8 -1.2 -1.6 -1.4 -1.9 -0.3 0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.7 1.4 3.0 1.2 1.1 1.2 0.7 1.6 1.7 0.6 0.8
Whole body water mass 0.4 2.5 9.3 -1.6 0.4 1.2 1.5 0.6 -1.1 -3.0 -1.6
Leg predicted mass (right) 0.7 3.9 15.9 -2.0 -0.6 0.4 1.3 -0.3 -1.9 -4.0 -2.3
Arm fat mass (left) 1.0 4.2 12.7 -2.2 -0.4 -0.5 1.6 -0.4 -2.7 -3.6 -2.4
Number of self-reported non-cancer illnesses 0.2 0.4 0.9 -0.1 -0.7 -1.0 -0.8 -0.5 -0.4 0.7 0.5
Average weekly champagne plus white wine intake 1.7 2.3 6.0 -0.7 1.2 2.2 2.5 1.6 0.5 -1.1 -1.3
Miserableness 1.9 3.2 5.8 0.6 2.3 1.9 1.6 1.6 2.4 1.6 1.7
Guilty feelings 1.4 2.2 5.2 -1.3 2.0 1.8 2.3 0.5 1.5 -0.6 -0.5
Wears glasses or contact lenses 0.7 0.8 3.2 -0.1 0.3 1.1 -0.0 1.0 0.9 1.8 0.5
Ever taken oral contraceptive pill 0.9 1.0 1.8 -0.9 0.6 1.2 1.3 -0.1 -1.2 -0.9 -1.2
Hearing aid user 2.0 2.3 7.5 0.5 -0.1 0.1 -1.1 0.2 2.3 2.1 2.7
Mother’s age at death 0.4 0.5 1.1 0.3 0.5 0.8 -0.0 0.7 0.5 1.0 1.1
Financial situation satisfaction 0.9 1.1 3.6 -0.3 -0.9 -1.2 -0.8 -0.9 -1.9 -0.8 -0.9
Tinnitus: Yes, now most or all of the time 0.4 0.5 1.3 0.1 -0.5 -0.5 0.6 -1.1 -0.8 -0.8 -0.6
Commuting to job workplace: Public transport 0.7 0.8 1.6 1.1 -0.0 -0.3 -1.0 -0.8 -0.9 1.3 0.9
Eye problems/disorders: Glaucoma 2.3 2.7 8.4 -0.9 -2.9 -1.4 -1.6 -2.4 -0.8 1.0 -0.0
Medication: Blood pressure 0.4 0.8 2.3 1.0 -0.5 0.4 -1.0 1.5 0.9 0.3 1.0
Pain type(s) experienced in last month: Hip pain 1.1 1.3 4.9 0.4 0.3 -2.2 -0.6 -1.8 -1.4 -0.2 -0.3
Supplements: Fish oil (including cod liver oil) 1.7 2.2 6.2 -0.4 -2.5 -2.1 -1.4 -1.8 -0.9 0.3 -0.8
High cholesterol (Self-reported) 0.6 1.0 2.5 1.2 1.3 0.5 0.7 1.6 1.1 0.4 0.5
Medication: Bendroflumethiazide 0.3 0.5 2.0 -0.7 0.9 0.2 0.2 1.4 0.6 -0.0 0.6
Medication: Paracetamol 0.4 0.6 2.1 -0.9 -0.1 -1.5 -0.1 -0.8 -0.8 -0.8 -0.6
Medication: Lisinopril 0.3 0.4 2.1 -0.5 -0.2 -0.5 0.0 -0.1 1.4 0.8 0.4
Medication: Atorvastatin 0.8 1.0 1.7 0.6 -1.3 0.4 -1.0 1.1 0.9 1.3 1.0
Illnesses of father: High blood pressure 1.2 1.5 3.9 2.0 0.6 -0.2 -1.0 0.8 0.7 1.5 1.9
Alcohol drinker status: Never 1.2 1.5 3.1 -1.2 -1.8 -0.2 0.0 -0.8 -1.6 -0.9 -1.8
Ever smoked 0.5 0.9 2.7 1.6 1.6 0.5 -0.0 0.6 -0.3 0.1 1.1
Basal metabolic rate 0.5 2.8 9.8 -1.8 0.2 1.1 1.7 0.5 -1.3 -3.1 -1.8
Leg fat percentage (left) 0.2 0.6 1.4 -0.9 -0.4 -0.5 0.7 0.1 -1.2 -1.2 -0.7
Arm fat-free mass (left) 0.3 1.6 5.8 -1.1 0.4 1.0 1.3 0.6 -1.1 -2.4 -1.1
Number of operations (self-reported) 0.8 1.2 3.3 -1.8 -0.9 -0.2 1.1 -0.2 0.3 -1.3 -1.6
Average weekly beer plus cider intake 0.7 1.1 2.9 -0.4 -1.1 -1.7 -1.2 -1.5 -0.4 0.5 0.0
Irritability 1.9 3.2 11.9 -0.1 1.6 2.1 1.3 2.2 3.4 0.5 0.6
Risk taking 0.6 0.9 2.1 -1.2 -1.0 -0.2 0.2 -0.7 -0.7 -1.4 -1.4
Ever had prostate specific antigen (PSA) test 2.3 2.6 5.8 1.3 0.9 2.4 0.0 2.2 1.4 1.8 1.7
Fractured/broken bones in last 5 years 1.0 1.2 2.4 1.1 -1.4 0.0 -1.3 0.4 0.8 1.6 1.3
Age started oral contraceptive pill 2.9 3.6 8.3 0.8 -2.7 -2.7 -2.9 -1.8 -1.3 0.5 0.6
Diastolic blood pressure, automated reading 0.3 1.1 3.9 1.0 0.4 0.6 -0.7 0.9 0.8 1.1 2.0
Ever depressed for a whole week 1.4 1.7 6.1 -2.5 0.1 0.3 1.0 -1.4 -1.4 -1.1 -1.3
Unable to work because of sickness or disability 0.4 0.5 2.2 -0.6 -0.7 -0.4 -0.6 -1.5 -0.5 -0.2 -0.2
Commuting to job workplace: Cycle 2.0 2.4 6.0 -1.7 1.9 1.6 2.5 0.6 -0.3 -1.1 -1.6
Myopia 0.6 0.9 1.9 0.4 0.6 0.8 1.2 0.6 -1.3 -1.4 -0.5
Vascular/heart problems diagnosed by doctor 0.5 1.3 4.3 -0.9 1.5 0.3 2.1 -1.1 -0.3 -0.6 -1.2
Cholesterol lowering medication 1.7 2.4 4.8 -0.4 1.5 1.9 2.0 2.2 2.1 -0.3 -0.2
Medication: Omeprazole (e.g. Zanprol) 2.2 2.7 6.0 -2.4 -1.1 -0.5 0.6 -1.2 -1.5 -2.3 -2.2
Pain experienced in last month 0.8 1.4 6.1 -0.4 0.6 2.5 0.2 1.9 0.4 0.6 0.6
Supplements: Calcium 1.2 1.3 3.5 -0.9 -0.6 0.8 0.7 0.5 -1.1 -1.8 -1.9
Basal cell carcinoma (self-reported) 0.5 0.5 1.7 -0.0 -1.3 -0.3 -0.3 -0.6 -0.8 -0.6 -1.1
Heart attack/myocardial infarction (self-reported) 0.3 0.4 1.6 1.3 -0.8 -0.1 -0.7 0.5 0.3 0.4 0.4
Deep venous thrombosis (DVT) (self-reported) 1.2 1.5 3.6 -0.8 -1.9 -0.5 -0.8 -0.4 -1.9 -1.6 -0.9
Heart disease (siblings) 0.4 0.4 1.6 -0.7 0.5 0.5 0.9 0.5 0.1 -1.3 -0.1
Alcohol drinker status: Previous 0.7 0.8 1.6 0.1 1.2 -0.9 0.4 -1.2 -1.3 -0.9 0.0
Pack years of smoking 0.5 0.7 2.1 1.3 -0.4 -0.2 -1.0 1.4 -0.4 -0.5 0.5
Impedance of whole body 1.1 5.4 19.0 3.0 0.2 0.5 -1.6 1.0 2.0 4.4 2.7
Leg fat mass (left) 0.5 1.8 6.2 -1.3 -0.8 -0.3 0.9 0.1 -1.8 -2.5 -1.4
Arm predicted mass (left) 0.4 1.9 6.6 -1.3 0.5 1.1 1.6 0.6 -0.8 -2.6 -1.2