Best TWAS P=1.26e-10 · Best GWAS P=3.84e-09 conditioned to 0.0032
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | WDR75 | 0.05 | 0.04 | lasso | 2 | 0.03 | 0.0012 | -5.5 | 5.6 | 2.0e-08 | -0.59 | 0.04 | 0.86 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | WDR75 | 0.16 | 0.00 | lasso | 9 | 0.00 | 0.2640 | -5.3 | 5.3 | 8.8e-08 | -0.70 | 0.04 | 0.24 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | WDR75 | 0.05 | 0.04 | lasso | 4 | 0.03 | 0.0012 | -5.2 | 5.2 | 1.8e-07 | -0.56 | 0.10 | 0.87 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | COL5A2 | 0.04 | 0.00 | blup | 79 | 0.02 | 0.0059 | -5.5 | 6.4 | 1.3e-10 | -0.53 | 0.02 | 0.59 | TRUE |