TWAS
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Traits
:
Impedance of leg (right)
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chr2:189,611,749-191,029,604
Best TWAS P=1.26e-10 · Best GWAS P=3.84e-09 conditioned to 0.0032
189.6M
189.8M
190M
190.2M
190.4M
190.6M
190.8M
191M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
COL5A2
0.04
0.00
blup
79
0.02
0.0059
-5.5
6.4
1.3e-10
-0.53
0.02
0.59
TRUE
1
GTEx
Adipose Subcutaneous
WDR75
0.05
0.04
lasso
2
0.03
0.0012
-5.5
5.6
2.0e-08
-0.59
0.04
0.86
FALSE
2
GTEx
Breast Mammary Tissue (Male)
WDR75
0.16
0.00
lasso
9
0.00
0.2640
-5.3
5.3
8.8e-08
-0.70
0.04
0.24
FALSE
3
GTEx
Skin Sun Exposed Lower leg
WDR75
0.05
0.04
lasso
4
0.03
0.0012
-5.2
5.2
1.8e-07
-0.56
0.10
0.87
FALSE