[Hub]/) : Traits : Impedance of leg (right) : ← →

chr2:241,239,377-242,767,801

Best TWAS P=1.87e-10 · Best GWAS P=1.24e-09 conditioned to 0.722

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Whole Blood	PASK	0.25	0.15	enet	10	0.21	4.4e-19	5.7	-6.4	1.9e-10	-0.93	0.03	0.97	TRUE
11	YFS	Blood	PASK	0.31	0.46	lasso	11	0.48	1.8e-181	5.6	-6.1	9.1e-10	-0.82	0.10	0.90	FALSE
6	GTEx	Small Intestine Terminal Ileum	MTERFD2	0.37	0.24	lasso	3	0.18	7.3e-05	5.8	-6.0	1.5e-09	-0.67	0.04	0.78	FALSE
9	NTR	Blood	PASK	0.08	0.09	bslmm	437	0.09	1.0e-26	5.8	-6.0	1.9e-09	-0.71	0.03	0.97	FALSE
7	GTEx	Testis	MTERFD2	0.43	0.17	enet	32	0.25	1.4e-11	5.9	5.8	7.4e-09	0.74	0.02	0.98	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	SNED1	0.17	0.12	lasso	4	0.14	5.2e-18	4.3	5.6	2.1e-08	0.55	0.98	0.02	FALSE
1	GTEx	Heart Left Ventricle	PASK	0.10	0.03	lasso	6	0.03	9.4e-03	-4.0	-5.6	2.6e-08	-0.47	0.07	0.56	FALSE
3	GTEx	Muscle Skeletal	PASK	0.06	0.00	enet	13	0.01	8.6e-02	4.3	-5.5	2.9e-08	-0.31	0.06	0.25	FALSE
12	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PASK	0.04	0.00	blup	92	0.01	3.2e-02	5.9	-5.4	7.8e-08	-0.78	0.02	0.61	FALSE
2	GTEx	Lung	PASK	0.09	0.02	lasso	2	0.03	3.7e-03	-4.1	-5.4	8.3e-08	-0.32	0.44	0.05	FALSE
5	GTEx	Skin Not Sun Exposed Suprapubic	PASK	0.28	0.16	enet	17	0.19	1.9e-10	4.3	-5.3	9.9e-08	-0.43	0.97	0.02	FALSE
4	GTEx	Nerve Tibial	PASK	0.26	0.18	enet	12	0.22	1.0e-15	4.3	-5.3	1.0e-07	-0.62	0.98	0.02	FALSE