[Hub]/) : Traits : Impedance of leg (right) : ← →

chr2:241,239,377-242,767,801

Best TWAS P=1.87e-10 · Best GWAS P=1.24e-09 conditioned to 0.722

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Heart Left Ventricle PASK 0.10 0.03 lasso 6 0.03 9.4e-03 -4.0 -5.6 2.6e-08 -0.47 0.07 0.56 FALSE
2 GTEx Lung PASK 0.09 0.02 lasso 2 0.03 3.7e-03 -4.1 -5.4 8.3e-08 -0.32 0.44 0.05 FALSE
3 GTEx Muscle Skeletal PASK 0.06 0.00 enet 13 0.01 8.6e-02 4.3 -5.5 2.9e-08 -0.31 0.06 0.25 FALSE
4 GTEx Nerve Tibial PASK 0.26 0.18 enet 12 0.22 1.0e-15 4.3 -5.3 1.0e-07 -0.62 0.98 0.02 FALSE
5 GTEx Skin Not Sun Exposed Suprapubic PASK 0.28 0.16 enet 17 0.19 1.9e-10 4.3 -5.3 9.9e-08 -0.43 0.97 0.02 FALSE
6 GTEx Small Intestine Terminal Ileum MTERFD2 0.37 0.24 lasso 3 0.18 7.3e-05 5.8 -6.0 1.5e-09 -0.67 0.04 0.78 FALSE
7 GTEx Testis MTERFD2 0.43 0.17 enet 32 0.25 1.4e-11 5.9 5.8 7.4e-09 0.74 0.02 0.98 FALSE
8 GTEx Whole Blood PASK 0.25 0.15 enet 10 0.21 4.4e-19 5.7 -6.4 1.9e-10 -0.93 0.03 0.97 TRUE
9 NTR Blood PASK 0.08 0.09 bslmm 437 0.09 1.0e-26 5.8 -6.0 1.9e-09 -0.71 0.03 0.97 FALSE
10 ROSMAP Brain Pre-frontal Cortex SNED1 0.17 0.12 lasso 4 0.14 5.2e-18 4.3 5.6 2.1e-08 0.55 0.98 0.02 FALSE
11 YFS Blood PASK 0.31 0.46 lasso 11 0.48 1.8e-181 5.6 -6.1 9.1e-10 -0.82 0.10 0.90 FALSE
12 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PASK 0.04 0.00 blup 92 0.01 3.2e-02 5.9 -5.4 7.8e-08 -0.78 0.02 0.61 FALSE