TWAS hub - MTERFD2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.42400	0.0460	0.0e+00	0.170	0.330	0.340	0.331	0.341	3.2e-20	3.3e-41	1.1e-42	2.1e-41	5.8e-43
2	GTEx	Brain Cerebellum	0.51300	0.1200	1.5e-03	0.110	NA	0.110	NA	0.201	3.9e-04	NA	4.0e-04	NA	1.4e-06
3	GTEx	Breast Mammary Tissue	0.19800	0.0740	4.3e-03	0.044	NA	0.123	NA	0.145	2.5e-03	NA	7.5e-07	NA	6.5e-08
4	GTEx	Breast Mammary Tissue (Male)	0.11354	0.1308	2.3e-01	-0.004	NA	0.051	NA	-0.001	4.0e-01	NA	2.5e-02	NA	3.5e-01
5	GTEx	Breast Mammary Tissue (Female)	0.00818	0.0590	4.6e-01	-0.004	NA	0.012	NA	-0.003	4.3e-01	NA	1.4e-01	NA	4.1e-01
6	GTEx	Esophagus Gastroesophageal Junction	0.22800	0.0820	4.5e-03	-0.008	NA	0.001	NA	0.005	8.7e-01	NA	2.9e-01	NA	2.1e-01
7	GTEx	Lung	0.13690	0.0512	3.3e-03	0.011	NA	0.023	NA	0.003	4.5e-02	NA	6.4e-03	NA	1.7e-01
8	GTEx	Nerve Tibial	0.18440	0.0553	1.6e-04	0.075	NA	0.120	NA	0.115	5.3e-06	NA	8.1e-09	NA	1.7e-08
9	GTEx	Small Intestine Terminal Ileum	0.37100	0.1080	1.6e-03	0.244	NA	0.081	NA	0.182	3.5e-06	NA	7.4e-03	NA	7.4e-05
10	GTEx	Testis	0.42600	0.0870	2.3e-07	0.166	NA	0.253	NA	0.241	7.4e-08	NA	1.4e-11	NA	4.8e-11
11	GTEx	Thyroid	0.11500	0.0450	2.4e-03	0.093	NA	0.072	NA	0.077	1.3e-07	NA	3.4e-06	NA	1.8e-06
12	GTEx	Whole Blood	0.10200	0.0320	4.7e-05	0.055	NA	0.060	NA	0.058	8.0e-06	NA	3.0e-06	NA	4.8e-06
13	NTR	Blood	0.07910	0.0173	1.7e-11	0.037	0.042	0.059	0.063	0.062	4.7e-12	1.7e-13	2.0e-18	2.0e-19	2.6e-19
14	ROSMAP	Brain Pre-frontal Cortex	0.11660	0.0278	7.2e-07	0.048	0.064	0.070	0.063	0.067	7.8e-07	1.3e-08	2.2e-09	1.7e-08	5.5e-09
15	TCGA	Breast Invasive Carcinoma	0.03200	0.0139	6.8e-05	0.005	0.020	0.014	NA	0.017	2.5e-02	4.6e-05	5.8e-04	NA	1.8e-04
16	TCGA	Kidney Renal Papillary Cell Carcinoma	0.07900	0.0400	5.9e-03	0.075	0.028	0.027	NA	0.040	4.4e-05	9.7e-03	1.1e-02	NA	2.4e-03
17	TCGA	Prostate Adenocarcinoma	0.04910	0.0260	6.1e-03	0.004	0.004	0.004	NA	0.005	1.0e-01	9.9e-02	1.1e-01	NA	8.7e-02
18	TCGA	Testicular Germ Cell Tumors	0.29000	0.1100	1.7e-04	0.147	0.119	0.047	NA	0.107	7.4e-06	5.4e-05	8.9e-03	NA	1.3e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Migraine (self-reported)	5.1	6.3	16.8	3.0	1.7	1.3	2.6	0.4	0.4	-0.3	3.9	2.4	-1.9	2.6	-0.7	3.5	3.6	-2.8	1.1	-3.4	-4.1
Qualifications: O levels/GCSEs or equivalent	3.8	6.0	12.0	-3.2	-2.6	-2.7	-2.2	-2.0	1.6	-3.4	-2.6	-1.6	1.3	-1.9	-0.2	-3.3	-3.0	2.5	1.5	3.5	2.4
Prostate Cancer	3.3	4.6	11.2	-1.8	-0.9	-2.4	-1.5	-1.5	-1.4	-0.3	-3.3	-3.3	2.4	-2.2	-0.7	-2.2	-2.6	1.4	-2.9	1.8	2.9
Illnesses of siblings: Diabetes	3.3	4.0	9.8	2.9	2.6	1.6	0.8	0.8	0.6	1.2	2.3	2.0	-1.2	2.7	0.1	3.1	2.9	-2.5	-0.3	-2.4	-1.8
Peak expiratory flow (PEF)	3.0	7.0	15.4	-2.7	-3.1	-2.3	0.0	0.8	-1.8	-3.2	-2.6	-3.9	2.9	-3.7	-3.0	-2.7	-2.9	3.6	0.3	2.4	1.5
High cholesterol (Self-reported)	2.9	5.2	10.8	-2.5	-2.2	-1.4	-1.4	0.4	-1.0	-1.9	-3.2	-3.0	2.1	-2.9	-1.3	-2.8	-2.8	2.6	-0.9	2.5	3.3
Forced vital capacity (FVC), Best measure	2.8	10.1	36.2	-1.9	-2.3	-1.3	-1.5	4.5	-1.2	-5.0	-1.6	-4.5	3.7	-4.6	-6.0	-1.8	-2.1	4.0	1.2	1.8	0.2
Impedance of arm (right)	2.7	12.4	44.2	-0.7	-0.6	1.9	-1.2	3.6	-2.9	-2.4	-1.5	-6.7	5.5	-6.2	-6.2	-1.7	-2.6	4.0	-1.9	2.0	1.8
Impedance of arm (left)	2.7	12.4	44.0	-0.4	-0.2	2.2	-0.6	3.5	-3.0	-2.5	-1.4	-6.6	5.6	-6.2	-6.5	-1.4	-2.5	3.9	-2.0	1.9	1.5
Supplements: Vitamin C	2.6	3.1	6.4	-1.6	-1.5	-1.5	-2.1	-0.0	-1.7	-0.3	-1.9	-2.0	1.5	-2.5	-1.0	-2.0	-2.4	2.3	0.1	2.5	1.7
Impedance of whole body	2.6	13.1	50.0	0.4	0.3	2.8	-0.7	3.2	-4.0	-1.8	-0.6	-7.1	6.5	-6.1	-6.5	-0.7	-2.0	3.7	-2.1	1.4	1.0
Ulcerative Colitis	2.5	3.6	11.1	2.1	1.7	1.2	3.3	1.7	1.5	1.7	2.3	1.6	-1.6	1.8	0.4	2.3	1.9	-2.5	-1.3	-1.9	-1.5
Forced vital capacity (FVC)	2.5	9.7	44.1	-0.9	-1.4	-0.7	-0.6	4.8	-2.1	-4.8	-1.1	-4.7	4.1	-4.6	-6.6	-1.0	-1.4	3.2	0.3	0.8	-0.3
Medication: Simvastatin	2.5	3.7	7.0	-2.5	-2.6	-1.7	-1.4	-0.5	-1.4	-1.8	-2.0	-2.4	1.7	-2.6	-1.5	-2.2	-1.6	2.2	1.4	1.9	1.9
Number of live births	2.5	3.6	7.7	2.3	2.0	0.8	1.3	-1.6	1.4	2.0	1.8	2.4	-1.7	2.6	1.3	2.3	2.2	-2.8	-0.6	-1.9	-1.5
Forced expiratory volume in 1-second (FEV1), Best measure	2.5	8.0	19.4	-2.8	-3.0	-2.7	-1.5	1.5	-1.2	-4.4	-2.3	-3.9	2.8	-3.9	-3.8	-2.5	-2.7	3.9	1.6	2.2	0.7
Qualifications: A levels/AS levels or equivalent	2.4	5.4	10.8	-2.8	-2.6	-2.5	-0.9	-0.6	0.1	-2.3	-1.9	-2.1	2.4	-2.7	-1.8	-2.8	-2.9	3.3	2.1	3.1	1.7
Myopia	2.3	3.4	11.6	-1.3	-1.9	-1.9	-0.4	-1.7	-3.4	-1.4	-0.9	-1.9	2.4	-2.7	-2.6	-0.8	-1.1	1.8	2.0	0.6	-1.1
Lung FEV1/FVC ratio	2.2	11.2	37.9	-4.2	-3.6	-5.3	-1.9	-6.2	-0.5	2.1	-3.0	1.0	-1.7	0.6	5.8	-3.4	-3.2	1.7	3.2	3.0	2.4
Medication: Cholesterol lowering	2.2	3.5	6.1	-2.2	-2.5	-1.5	-0.3	0.2	-1.3	-2.2	-2.0	-2.3	0.9	-2.3	-1.5	-2.3	-1.8	2.4	1.0	2.4	2.1
Comparative body size at age 10	2.2	6.0	11.4	2.7	2.3	1.3	1.9	0.1	2.1	1.6	3.3	3.2	-1.6	3.2	1.5	3.2	3.4	-2.6	1.1	-2.6	-3.3
Medication: Levothyroxine sodium	2.1	3.5	7.9	-2.5	-2.5	-1.6	-1.6	-1.3	-1.8	-2.3	-1.3	-1.6	0.3	-2.0	0.9	-2.5	-1.7	2.5	2.8	1.7	0.2
Impedance of leg (left)	2.1	10.2	41.3	0.6	0.3	2.6	-0.6	2.2	-4.5	-0.7	-0.2	-6.4	6.2	-5.2	-5.0	-0.4	-1.7	3.0	-2.5	0.8	0.6
Number of operations (self-reported)	2.1	3.1	10.1	-2.5	-1.8	-2.2	-1.4	-0.5	1.3	-1.4	-3.2	-1.0	0.3	-1.4	-0.5	-2.5	-2.3	1.5	-0.3	1.9	2.2
Hypothyroidism/myxoedema (self-reported)	2.0	3.9	10.0	-2.5	-2.5	-1.8	-1.1	-1.1	-2.6	-1.3	-1.2	-1.8	0.7	-2.7	0.1	-2.6	-1.7	2.9	3.2	1.5	-0.3
Cardiovascular Disease	1.9	6.3	13.8	-2.7	-1.9	-0.8	-1.3	1.3	-0.3	-1.1	-3.7	-3.4	2.4	-3.7	-1.0	-2.8	-3.0	3.4	-0.9	3.1	3.6
Sitting height	1.9	13.5	35.6	-2.6	-2.5	-1.1	-0.7	3.5	-2.2	-3.9	-2.4	-5.6	5.1	-5.9	-6.0	-2.7	-3.1	5.4	2.1	3.1	0.7
Forced expiratory volume in 1-second (FEV1)	1.9	6.4	18.0	-1.7	-2.0	-1.7	-0.6	2.4	-2.2	-3.9	-1.6	-4.0	3.1	-3.9	-4.2	-1.5	-1.8	3.3	0.9	1.3	0.2
Qualifications: NVQ or HND or HNC or equivalent	1.9	2.3	9.3	-0.9	-1.5	-0.3	-0.7	1.7	-1.6	-3.0	-0.5	-2.2	1.6	-1.7	-2.5	-0.9	-0.9	1.4	0.8	1.3	0.3
Forced expiratory volume in 1-second (FEV1), predicted	1.9	4.0	11.5	-1.4	-1.0	-1.1	-0.4	1.8	-0.5	-1.0	-2.1	-3.3	3.2	-3.4	-3.4	-1.4	-2.0	2.4	0.0	1.7	0.9
Smoking status: Current	1.9	3.1	8.3	1.9	1.8	1.5	2.4	0.4	1.1	2.9	1.3	1.0	-1.1	1.2	0.4	1.7	1.7	-2.6	-2.8	-2.0	-0.9
Major Depression (MDD)	1.8	2.2	8.2	1.9	1.9	1.9	0.0	2.9	0.2	-0.1	2.3	0.0	-0.6	1.1	-0.4	2.0	2.0	-0.7	1.4	-0.5	-1.7
Impedance of leg (right)	1.8	8.7	36.5	0.4	0.2	1.9	-0.8	1.9	-4.0	-1.0	-0.1	-6.0	5.8	-4.8	-4.8	-0.5	-1.6	2.8	-1.8	1.0	0.5
Trunk fat percentage	1.8	7.3	21.5	-1.6	-0.9	-1.8	-1.2	1.3	-1.2	-2.7	-3.0	-4.6	3.4	-4.5	-4.1	-2.0	-3.0	3.2	-0.2	2.7	2.0
Current tobacco smoking	1.8	2.9	8.3	1.8	1.6	1.5	2.1	0.0	1.3	2.8	1.1	1.1	-1.4	1.3	0.7	1.5	1.6	-2.7	-2.9	-1.7	-0.7
Bilateral oophorectomy (both ovaries removed)	1.8	2.1	5.5	-1.7	-1.7	-2.4	-0.4	-1.7	0.8	-0.9	-1.7	-2.2	1.3	-1.8	-1.1	-1.5	-1.5	1.1	0.5	1.3	0.9
Illnesses of mother	1.8	2.2	5.2	1.6	1.5	1.0	2.1	-0.2	0.3	1.6	1.4	1.5	-1.6	1.4	0.7	1.7	1.5	-2.0	-1.6	-2.3	-1.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.8	2.1	5.9	1.4	1.6	1.1	1.3	-0.0	1.1	1.4	0.6	1.4	-2.4	2.2	1.9	1.3	1.3	-2.0	-1.8	-0.5	0.0
Cholesterol lowering medication	1.8	2.6	5.5	-2.0	-2.1	-1.3	-1.4	-0.7	-1.0	-1.5	-2.0	-2.1	1.7	-2.4	-1.4	-1.7	-1.7	1.4	-0.2	1.0	1.8
Family relationship satisfaction	1.7	2.1	8.2	1.8	1.9	1.5	1.3	2.9	1.5	-0.2	1.3	0.9	-0.5	1.6	-1.0	1.9	1.6	-1.7	-0.8	-0.9	-0.6
Supplements: Fish oil (including cod liver oil)	1.7	2.2	4.0	-1.8	-1.8	-1.9	-0.1	0.1	-1.9	-0.7	-1.5	-1.4	1.1	-1.2	-1.1	-1.9	-1.7	2.0	0.8	1.8	1.8
Heart attack/myocardial infarction (self-reported)	1.7	2.2	6.9	-1.2	-1.6	-1.1	0.2	-0.0	-1.9	-1.9	-1.2	-2.2	1.1	-2.6	-2.4	-1.1	-1.1	1.6	0.6	0.9	0.5
Rheumatoid Arthritis	1.6	2.2	5.0	-2.2	-2.2	-1.4	-0.9	-1.3	-0.2	-1.7	-2.2	-0.5	-0.9	-0.9	1.7	-2.2	-1.5	1.1	-0.5	0.8	1.8
Trunk fat mass	1.6	6.8	15.6	-2.1	-1.4	-2.6	-1.3	1.3	-0.5	-2.9	-3.0	-3.8	2.6	-4.0	-3.6	-2.3	-3.0	3.1	0.7	2.9	2.0
Body fat percentage	1.6	6.5	18.2	-1.6	-0.9	-1.9	-1.4	0.9	-1.0	-2.4	-3.0	-4.3	3.2	-4.1	-3.6	-2.0	-2.9	3.0	0.2	2.8	2.1
Pack years of smoking	1.6	2.4	5.1	2.3	1.9	1.6	0.9	1.2	0.2	-1.0	1.8	0.5	-0.9	1.3	-0.8	2.0	1.8	-2.1	-1.9	-1.6	-1.8
Age at First Birth	1.5	2.2	7.2	-2.2	-2.6	-2.7	-1.4	-0.1	-0.5	-1.9	-0.5	-1.1	0.7	-1.1	-1.1	-1.6	-1.4	1.1	1.9	0.8	-0.8
Coronary Artery Disease (CAD)	1.5	1.8	7.8	1.1	0.9	2.8	-0.0	2.1	1.8	0.4	0.6	1.5	-1.8	1.8	1.3	0.9	0.9	-1.1	-0.5	-0.3	0.4
Chronotype (morning person)	1.5	3.6	10.9	-1.1	-0.6	0.0	-1.8	0.4	-2.8	-1.2	-0.9	-3.3	2.9	-2.7	-2.7	-1.4	-1.9	2.9	0.0	1.6	0.3
Diabetes (father)	1.5	1.9	5.8	1.6	1.4	1.3	2.3	0.6	-0.5	2.4	0.8	0.4	-0.2	0.6	-0.5	1.7	1.7	-1.4	-1.7	-1.8	-0.7
High blood pressure (mother)	1.5	2.1	5.2	-1.7	-1.8	-1.0	-2.3	-0.1	1.2	-1.9	-1.5	-1.3	1.3	-0.7	0.1	-1.5	-1.5	1.8	1.3	2.0	1.0
Heart attack	1.5	2.0	6.3	-1.2	-1.6	-1.2	0.2	-0.1	-1.9	-1.8	-1.1	-2.0	1.0	-2.5	-2.2	-1.1	-1.0	1.5	0.7	0.8	0.5
Smoking status: Previous	1.5	2.3	6.3	-1.9	-1.3	-1.9	-1.6	-0.4	1.0	-0.8	-1.8	0.2	-0.4	-0.2	0.5	-1.8	-1.4	1.5	2.1	2.4	2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.2	7.3	-2.3	-2.3	-2.2	-1.2	0.3	-1.5	-2.6	-1.4	-1.8	1.0	-2.0	-0.4	-2.2	-1.9	2.7	1.5	1.5	0.7
Supplements: Calcium	1.5	1.6	6.0	-1.0	-1.0	-0.6	0.1	-0.6	0.2	-0.8	-0.8	-2.3	1.9	-2.5	-2.0	-1.1	-1.3	1.4	0.3	0.9	0.4
Breast Cancer	1.4	3.3	6.3	2.1	2.4	2.3	1.1	2.5	0.1	2.3	1.8	1.3	-0.8	0.8	-1.1	2.2	1.9	-1.6	-1.8	-2.5	-1.6
Number of incorrect matches in round	1.4	2.3	8.8	1.4	1.8	1.6	1.2	2.5	3.0	2.0	0.7	1.2	-1.1	1.4	0.2	1.4	1.6	-0.6	-1.2	-1.0	0.9
Had menopause	1.4	1.8	4.7	-1.9	-2.0	-2.2	-1.1	-1.7	0.5	0.0	-1.4	0.7	-1.1	0.1	1.8	-1.6	-1.3	0.5	1.8	0.8	0.3
Hip circumference	1.4	6.1	15.4	-2.2	-1.6	-2.5	-1.2	1.6	0.0	-2.8	-2.9	-3.1	2.4	-3.6	-3.9	-2.2	-2.8	3.0	0.8	2.5	1.6
Number of children fathered	1.4	1.6	5.8	0.2	0.2	-0.6	0.3	-1.4	1.9	-0.5	0.4	2.0	-2.4	2.4	1.7	0.4	0.7	-1.6	0.6	-0.2	-0.4
Medication for cholesterol	1.4	2.2	6.1	0.5	0.1	-0.9	0.0	-2.3	1.1	-0.0	1.5	2.5	-2.2	2.3	1.3	0.7	1.3	-0.9	2.4	-0.5	-1.5
Ulcerative Colitis (UC)	1.3	2.4	11.8	1.0	0.7	-0.0	3.4	0.0	2.5	0.2	1.4	1.6	-2.6	1.6	0.9	1.0	0.9	-2.1	-1.1	-1.3	-0.5
Pack years adult smoking proportion	1.3	2.0	4.8	2.2	2.0	1.3	0.6	0.8	-0.0	-1.0	1.6	0.3	-0.8	1.0	-0.6	1.9	1.6	-2.0	-1.9	-1.3	-1.8
Medication: Blood pressure	1.3	2.3	4.6	-1.8	-1.6	-0.4	-0.2	1.2	-1.6	-1.8	-1.6	-2.2	0.1	-1.9	-0.5	-1.8	-1.5	1.9	0.1	1.7	2.0
Mineral and other dietary supplements	1.3	1.7	3.6	1.5	1.4	1.2	-0.3	-1.0	0.8	1.1	1.0	1.2	-1.1	1.5	1.5	1.6	1.5	-1.9	-1.1	-1.7	-1.4
Tinnitus: Yes, now most or all of the time	1.3	1.5	5.2	-0.5	-0.5	-0.3	-1.0	1.6	-2.3	-1.5	-0.2	-2.2	1.8	-1.2	-1.3	-0.7	-1.2	1.4	-0.6	0.6	0.3
Medication: Paracetamol	1.3	2.0	7.5	1.5	1.4	0.5	0.8	2.1	0.8	-0.4	2.2	0.0	0.1	0.1	-2.1	1.8	1.6	-0.3	1.6	-1.0	-2.7
Schizophrenia vs Biploar Disorder	1.2	1.6	6.7	0.1	-0.3	-1.1	0.1	-2.6	0.6	0.5	1.3	1.7	-2.0	1.3	1.6	-0.1	0.3	-1.4	0.2	-1.4	-1.8
Fasting Glucose	1.2	1.4	3.6	-1.4	-1.6	-1.1	-1.2	-1.0	0.7	-1.9	-1.4	-0.0	-1.1	-0.1	1.1	-1.6	-1.3	0.3	-0.8	1.1	1.3
Height	1.2	23.1	86.5	-3.7	-4.3	-2.5	-2.2	3.8	-0.7	-7.7	-3.0	-6.4	4.8	-6.9	-9.3	-3.9	-3.8	6.1	2.9	3.5	1.8
Taking other prescription medications	1.2	1.9	6.5	-1.4	-1.3	0.1	-0.1	1.0	-2.0	-1.9	-1.4	-1.9	0.8	-2.6	-1.4	-1.4	-1.4	1.3	-0.6	0.4	0.3
Arm fat percentage (right)	1.2	4.7	10.7	-1.9	-0.9	-2.1	-1.7	0.5	-0.1	-1.8	-3.3	-2.9	1.8	-2.9	-1.8	-2.2	-2.8	2.5	0.1	3.0	2.6
Breastfed as a baby	1.2	1.5	3.1	-1.7	-1.3	-1.6	-0.8	0.6	-0.6	-1.2	-1.8	-0.6	0.3	-1.0	-0.7	-1.4	-1.1	1.5	0.9	1.5	1.7
Medication for cholesterol, blood pressure or diabetes	1.2	1.9	4.7	1.6	1.5	1.0	0.3	-0.8	1.1	1.4	1.8	2.2	-0.3	1.7	0.6	1.7	1.1	-1.7	-0.0	-1.7	-2.0
Wheeze or whistling in the chest in last year	1.2	2.1	5.1	2.3	1.9	1.3	1.6	0.9	1.8	0.9	1.6	1.3	-1.7	1.4	0.0	1.8	1.6	-1.8	-1.0	-0.6	-0.9
Whole body fat mass	1.2	4.9	9.8	-1.9	-1.2	-2.5	-1.2	1.0	-0.2	-2.5	-2.8	-3.0	2.0	-3.1	-2.9	-2.0	-2.6	2.6	0.8	2.6	1.9
Leg pain on walking	1.2	1.5	5.1	0.7	1.0	-0.3	0.2	-1.0	0.6	0.7	1.1	2.2	-1.5	2.0	2.1	0.8	1.0	-1.4	-0.0	-1.4	-1.2
Bipolar Disorder (2018)	1.1	1.8	6.6	-0.8	-0.4	0.7	0.6	2.6	0.1	-1.0	-1.7	-2.2	1.5	-1.7	-1.6	-0.7	-1.1	1.6	-0.5	1.3	1.3
Alzheimer’s Disease (in mother)	1.1	1.3	4.0	-1.3	-0.8	-1.2	-1.5	-0.5	0.5	0.0	-1.5	0.9	-0.5	0.5	2.0	-1.2	-0.8	0.5	1.4	1.3	1.9
Irritable Bowel Disease (IBD)	1.1	2.6	14.2	1.2	0.9	0.2	3.8	0.1	2.6	-0.4	1.0	1.1	-2.6	1.7	0.5	1.2	0.7	-2.2	-1.9	-1.1	-0.6
Body Mass Index (BMI) (2010)	1.1	1.6	4.1	1.2	1.6	0.9	0.1	0.4	2.0	0.3	0.3	1.8	-1.8	1.7	0.7	1.2	1.0	-1.7	-1.4	-0.9	-0.7
HDL Cholesterol	1.1	1.8	4.6	-1.5	-0.9	-0.1	-0.6	0.4	-0.8	-0.9	-1.4	-1.7	1.0	-1.8	-0.6	-1.9	-2.1	2.1	0.3	1.6	1.3
Number of treatments/medications taken	1.1	2.0	6.4	-0.9	-0.9	0.6	-0.3	1.7	-1.7	-1.6	-1.3	-2.5	1.1	-2.5	-1.6	-1.0	-1.4	1.4	-0.7	0.8	0.7
Illnesses of siblings	1.1	1.6	7.1	-1.6	-1.3	-1.9	-0.7	-2.7	0.4	0.9	-1.5	-0.1	0.7	-0.7	1.0	-1.6	-1.5	0.8	-0.2	0.3	1.4
Arm fat percentage (left)	1.1	4.3	10.0	-1.8	-0.7	-2.0	-1.4	0.6	0.1	-1.8	-3.2	-2.8	1.7	-2.8	-1.8	-2.1	-2.7	2.4	0.2	2.9	2.5
Friendships satisfaction	1.1	1.3	2.8	1.0	0.8	1.3	0.5	0.9	1.2	-0.5	1.4	1.4	-0.7	1.5	-0.6	1.3	1.0	-1.7	-0.2	-1.5	-1.7
Osteoarthritis (self-reported)	1.1	1.4	4.2	-1.2	-0.0	-0.2	-1.5	0.6	1.7	-1.4	-2.0	0.0	-0.1	-0.4	0.7	-1.2	-1.7	0.7	-1.2	0.6	2.0
Mother’s age at death	1.1	1.4	4.5	1.0	1.3	0.8	2.1	-0.4	1.4	1.7	1.5	0.7	-0.4	1.3	0.0	1.3	1.4	-1.0	0.1	-1.4	-0.9
Hypothyroidism (self reported)	1.0	2.2	10.3	-1.5	-1.4	-1.4	-0.8	-0.6	-2.1	-0.5	-0.4	-1.2	-0.1	-1.9	0.5	-1.8	-0.9	2.4	3.2	1.2	-0.8
Lung FVC	1.0	5.2	27.2	-1.1	-2.0	-1.5	-1.8	2.2	-1.0	-5.2	-0.7	-3.1	1.8	-3.1	-4.3	-0.7	-0.6	2.1	0.8	-0.3	-1.6
Father’s age at death	1.0	1.3	7.6	-1.3	-1.4	-2.0	-0.9	-2.8	0.5	-0.3	-0.5	1.0	-0.8	0.5	0.7	-1.2	-0.9	0.0	1.3	0.5	-0.1
Standing height	1.0	9.7	44.4	-1.9	-2.2	-1.2	-0.7	4.1	-0.4	-4.7	-1.5	-4.1	3.2	-4.6	-6.7	-1.9	-2.4	3.8	1.5	2.0	0.6
Mouth/teeth dental problems: Bleeding gums	1.0	1.2	2.7	-1.0	-1.1	-0.6	-1.4	-0.2	0.3	-1.5	-1.1	-1.5	0.5	-1.1	-0.8	-1.3	-1.5	1.1	0.1	1.6	1.5
Medication: Ventolin 100micrograms inhaler	1.0	1.3	6.1	-1.0	-1.1	-1.2	-2.5	0.4	-0.4	-1.0	-1.0	-1.2	0.7	-1.2	-1.3	-1.2	-0.8	1.0	0.5	1.4	1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.0	1.2	6.0	-0.5	-0.6	-0.3	-0.7	1.6	-2.5	-1.2	-0.4	-1.2	0.9	-1.2	-1.3	-0.4	-0.7	1.4	1.0	0.6	-0.5
Emphysema/chronic bronchitis	1.0	1.1	6.1	1.4	1.3	0.4	1.0	0.9	-0.7	2.5	0.5	0.5	-0.8	1.2	0.5	1.0	0.8	-1.5	-0.8	-0.4	-0.5
Medication: Ibuprofen	1.0	1.2	4.6	1.7	1.8	1.0	0.5	0.5	-0.2	-0.0	1.8	-0.1	0.4	0.4	-0.8	1.6	1.0	-0.2	0.7	-0.7	-2.1
Qualifications: nursing, teaching	1.0	1.6	9.2	-0.9	-0.5	-1.0	-1.1	0.8	-1.0	-0.5	-0.7	-0.7	1.3	-0.9	-0.5	-0.8	-0.8	2.4	3.0	1.7	0.4
Osteoporosis (self-reported)	1.0	1.2	3.5	1.4	0.7	1.1	0.9	1.0	-0.4	0.5	1.5	0.1	0.1	-0.1	-1.9	1.3	1.6	-1.1	-0.8	-1.6	-1.0
Wears glasses or contact lenses	1.0	1.2	6.0	-0.0	-0.5	0.3	-0.2	1.5	-2.4	-0.6	0.7	-1.2	1.0	-1.6	-1.7	0.1	-0.2	1.2	1.2	0.1	-1.1
Medication: Lisinopril	1.0	1.3	3.9	-1.7	-1.6	-1.4	-1.7	-0.4	0.1	-0.3	-1.6	-0.6	0.5	-0.8	-0.0	-1.4	-1.3	0.6	-0.2	1.2	2.0
Leg fat percentage (left)	1.0	3.8	10.0	-1.4	-0.7	-1.7	-1.3	0.2	-1.1	-1.2	-2.5	-3.2	2.6	-3.0	-1.9	-1.6	-2.3	2.4	0.2	2.3	2.0
Alzheimer’s Disease (in father)	0.9	0.9	4.8	0.6	1.0	1.1	2.2	1.6	-0.3	0.7	0.5	-0.3	0.2	-0.1	-0.2	0.6	0.2	-0.1	-2.2	-0.7	0.3
HbA1C	0.9	1.0	2.8	0.3	1.3	1.2	0.7	-0.4	1.7	0.5	0.2	1.3	-1.3	1.5	0.9	0.9	0.5	-1.2	-0.7	-1.0	-0.6
Diabetes (mother)	0.9	1.2	3.9	1.6	1.7	0.8	0.3	-0.4	2.0	0.8	1.3	0.6	-0.5	1.2	-0.7	1.3	1.2	-1.2	-1.0	-0.6	-0.3
Depression (self-reported)	0.9	1.0	4.4	0.2	0.5	-0.3	-0.3	-0.3	0.4	0.5	1.0	2.1	-1.6	1.6	1.6	0.6	0.9	-0.8	1.0	-0.9	-1.2
Medication: Paracetamol	0.9	1.4	5.4	1.1	1.3	0.2	0.4	2.3	0.5	-0.9	1.5	0.2	0.2	-0.2	-2.0	1.4	1.1	-0.4	0.7	-1.1	-2.2
Leg fat percentage (right)	0.9	3.3	8.2	-1.3	-0.5	-1.9	-1.4	0.1	-0.8	-1.3	-2.4	-2.9	2.2	-2.6	-1.8	-1.5	-2.1	2.1	0.5	2.3	1.9
Had major operations	0.9	1.1	3.2	-0.7	0.1	-0.4	-0.8	0.2	1.3	1.6	-1.5	0.5	-1.8	0.7	1.5	-0.8	-0.8	0.3	-0.5	0.9	1.6
Eye problems/disorders: Cataract	0.9	1.0	3.6	0.1	0.3	1.1	-0.6	0.9	-1.2	-0.1	-1.2	-1.9	1.4	-1.1	-0.6	-0.5	-1.1	0.6	-1.8	0.5	1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	4.9	-0.2	-0.1	0.1	0.8	-0.4	1.4	0.6	0.3	1.6	-2.0	1.4	2.2	-0.1	0.5	-0.5	1.3	0.1	-0.0
Medication: Aspirin	0.9	1.2	4.8	-0.9	-1.3	-0.6	-0.7	0.4	-1.6	-2.2	-0.8	-1.2	0.3	-1.6	-1.3	-0.8	-0.6	1.1	1.0	0.5	0.5
Guilty feelings	0.9	1.3	4.1	1.9	1.8	2.0	0.6	2.0	-0.5	-0.1	1.1	0.2	0.6	0.5	-0.9	1.5	1.0	-0.8	-1.0	-0.7	-0.7
Ovarian Cancer	0.8	1.0	7.9	0.5	0.3	1.5	1.1	2.8	-0.9	-0.3	0.6	-0.1	0.6	-0.3	-1.0	0.6	0.5	-0.1	-1.4	-1.3	-0.3
Vitamin and mineral supplements	0.8	1.1	2.5	1.4	1.6	1.1	0.4	0.3	-0.5	1.3	0.7	0.7	-0.6	1.3	1.2	1.3	1.3	-0.9	-1.1	-1.2	-0.5
Supplements: Zinc	0.8	0.9	3.7	-0.6	-0.1	-0.3	-0.7	0.4	1.8	-1.1	-0.8	-0.4	0.5	0.0	0.7	-0.9	-1.0	0.8	0.8	1.9	1.1
Lung cancer (father)	0.8	0.9	3.6	-0.7	-0.4	-0.3	-0.8	-0.1	0.5	-0.1	-1.9	0.5	-1.3	0.3	1.5	-0.8	-1.0	0.2	-0.0	1.5	1.9
Hair/balding pattern: Pattern 4	0.8	2.0	18.6	-0.1	-0.4	1.0	-0.0	1.3	-4.3	1.1	0.3	-1.8	2.0	-1.7	-1.0	0.0	0.2	1.2	0.2	-0.4	0.4
Blood clot in the leg (DVT)	0.8	1.0	4.3	0.6	0.9	0.9	0.1	1.6	-0.4	0.4	-0.2	-1.3	1.4	-1.5	-2.1	0.4	-0.4	0.7	-1.4	-0.1	-0.6
Birth weight	0.8	1.7	5.3	-2.3	-2.0	-2.3	-1.1	-0.5	0.3	-1.6	-1.6	0.2	-0.1	-0.4	0.8	-1.8	-1.3	0.8	1.1	0.9	1.2
Eye problems/disorders: None of the above	0.8	0.9	3.3	-1.4	-1.5	-1.8	0.2	-1.4	1.2	-0.7	-0.2	0.2	-0.5	-0.4	0.7	-1.1	-0.7	0.5	1.0	0.7	-0.3
Comparative height size at age 10	0.8	4.3	16.0	-1.4	-1.4	-0.9	-1.6	3.0	1.0	-3.9	-0.6	-1.6	0.8	-2.3	-4.0	-1.3	-1.6	2.5	2.4	2.1	0.3
Knee pain experienced in last month	0.8	1.2	4.9	-1.1	-1.2	-2.2	-1.3	-1.5	0.9	-1.0	-0.0	1.4	-1.0	0.9	1.4	-0.8	-0.3	-0.4	0.9	-0.1	0.0
Hypertension (Self-reported)	0.8	2.2	6.4	-1.2	-0.6	0.3	-0.4	2.5	-0.5	-0.5	-1.7	-2.3	1.2	-2.4	-1.1	-1.3	-1.6	1.7	-1.1	1.6	1.8
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	3.6	0.8	1.1	1.0	0.1	1.4	-0.4	0.9	-0.2	-1.2	1.3	-1.4	-1.9	0.5	-0.3	0.6	-1.5	-0.2	-0.5
Heart disease (siblings)	0.8	1.0	2.4	1.0	0.4	1.2	1.0	1.0	-1.4	-1.2	1.1	-0.7	0.1	-0.5	-1.4	0.9	0.9	-0.4	-0.6	-1.2	-1.5
Intelligence (Savage-Jansen 2018)	0.7	2.0	12.3	-1.1	-1.4	-2.0	0.3	-0.9	1.6	-3.5	0.2	-0.8	0.5	-1.2	-1.6	-1.0	-0.8	1.3	2.2	1.1	-0.3
Crohns Disease (2012)	0.7	1.1	5.3	0.8	0.2	0.8	2.3	0.2	0.5	-1.0	1.2	-0.5	-0.1	-0.3	-1.5	0.9	0.6	-0.6	-0.6	-1.2	-2.0
Lupus	0.7	1.1	5.1	-0.7	-0.3	-1.1	0.8	-2.3	-0.3	0.8	-1.2	0.4	-1.2	0.5	1.7	-0.5	-0.6	-0.7	-1.5	0.2	1.5
Hand grip strength (right)	0.7	2.0	8.4	-0.4	-0.1	-0.6	-1.0	0.6	0.3	-0.8	-1.5	-2.4	2.9	-1.7	-2.8	-0.6	-0.8	1.1	-0.4	1.2	1.4
Tinnitus: Yes, but not now, but have in the past	0.7	0.8	3.8	1.4	1.2	0.3	1.3	-0.2	0.0	2.0	0.6	0.4	-0.5	0.7	0.9	1.1	0.8	-0.5	0.2	-0.2	-0.5
Qualifications: CSEs or equivalent	0.7	0.9	2.6	-0.2	0.5	-0.0	-0.6	0.6	-0.0	1.5	-1.4	-1.2	1.2	-1.1	-1.0	-0.4	-0.6	0.8	-1.1	0.7	1.6
Stomach or abdominal pain in last month	0.7	0.9	2.6	-1.5	-1.2	-0.7	-1.6	0.2	1.6	-0.8	-0.5	-0.3	0.6	-0.6	0.5	-1.4	-1.2	0.7	-0.0	0.6	0.8
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	6.9	-1.1	-1.1	-0.2	0.1	-0.1	2.6	-0.7	-0.4	0.7	-0.2	0.5	1.2	-0.6	-0.4	-0.1	0.3	0.8	1.1
Hair/balding pattern: Pattern 2	0.7	0.9	3.8	1.1	1.4	0.5	0.0	-0.4	0.3	0.3	0.4	0.8	-0.5	1.2	0.4	1.0	0.7	-1.7	-2.0	-1.2	-0.4
Had other major operations	0.7	0.9	3.5	-0.8	-0.5	-1.5	-0.4	-0.9	0.9	-0.5	-1.9	-0.6	0.3	-0.7	-0.8	-0.7	-1.0	-0.1	-1.8	0.6	1.1
Pain all over the body in last month	0.7	0.7	3.1	1.3	1.8	1.2	0.4	1.6	0.9	0.6	0.6	0.3	0.1	0.4	0.7	0.9	0.8	-0.6	-0.5	-0.5	-0.2
Falls in the last year	0.7	0.9	3.0	1.2	1.4	1.0	-0.4	1.7	0.3	0.1	0.3	-0.4	0.7	-0.2	-1.3	1.1	0.6	-0.8	-1.6	-1.0	-0.4
Arm fat mass (right)	0.7	3.1	7.3	-1.8	-1.1	-2.7	-1.1	0.3	0.6	-2.2	-2.7	-1.5	0.6	-1.9	-1.2	-1.9	-2.3	1.8	0.8	2.4	1.9
Ever highly irritable/argumentative for 2 days	0.7	0.8	2.4	1.1	1.2	0.9	0.6	-0.2	-0.7	-0.4	1.1	0.5	-0.4	0.4	-0.2	1.2	1.0	-1.1	-0.0	-1.4	-1.5
Gout (self-reported)	0.7	1.0	2.8	-1.4	-1.1	-1.6	0.3	-1.5	0.3	-1.2	-1.7	0.3	-0.5	-0.3	0.5	-1.3	-1.4	0.1	-0.3	0.6	1.3
Mean time to correctly identify matches	0.7	1.4	4.1	0.0	0.1	-0.7	-1.2	-1.8	-0.4	1.2	0.9	1.9	-1.8	1.5	1.6	0.3	0.4	-0.8	2.0	-0.3	-1.0
Medication: Aspirin	0.7	0.9	3.3	-0.6	-0.9	-0.4	-0.2	0.3	-1.8	-1.7	-0.8	-1.4	0.4	-1.5	-1.5	-0.5	-0.5	0.9	0.6	0.3	0.4
Handedness (chirality/laterality): Left-handed	0.7	0.9	5.6	0.8	1.3	1.7	-0.7	2.4	0.9	0.3	0.2	0.1	0.0	0.2	-0.5	0.6	0.2	-0.2	-1.6	-0.4	0.3
Financial situation satisfaction	0.7	0.9	4.4	0.7	0.7	0.7	-1.1	-1.1	2.1	1.1	1.0	0.7	0.0	1.1	0.4	0.7	0.5	-1.0	0.7	-0.4	-1.2
Illnesses of father: High blood pressure	0.7	0.8	5.3	0.7	0.8	0.6	0.3	-0.1	1.7	0.3	0.4	1.2	-1.0	1.1	2.3	0.4	0.4	-0.8	-0.3	0.3	0.5
Leg fat mass (left)	0.7	2.8	5.9	-1.6	-0.9	-2.4	-1.2	0.2	-0.1	-1.6	-2.4	-2.0	1.5	-2.2	-1.6	-1.6	-2.1	1.9	0.9	2.1	1.6
Schizophrenia (2018)	0.6	1.3	4.9	0.2	0.2	-0.8	-0.1	0.1	1.6	0.2	1.3	1.6	-2.2	1.6	1.5	0.5	1.0	-0.8	1.2	-0.1	-1.4
Verbal and Numeric Reasoning (VNR)	0.6	1.5	6.0	-1.3	-1.6	-1.9	-0.4	-1.6	1.4	-2.4	-0.4	-0.1	-0.2	-0.7	-1.3	-1.0	-0.6	0.6	1.8	1.1	-0.0
Schizophrenia (2014)	0.6	1.4	6.0	-0.2	-0.3	-0.9	-0.2	-0.7	1.8	-0.5	0.9	1.6	-2.4	1.6	1.8	0.1	0.6	-0.8	1.4	0.2	-1.3
Type 2 Diabetes (T2D) (2018)	0.6	1.1	5.9	-1.0	-1.3	-1.3	-0.6	-1.3	-0.3	-0.1	-0.9	-1.1	0.8	-1.1	-2.4	-0.7	-1.0	0.3	-0.8	0.5	0.7
Hand grip strength (left)	0.6	1.5	8.0	0.4	0.8	0.1	-1.0	0.5	0.5	-0.6	-0.6	-2.1	2.7	-1.3	-2.8	0.2	-0.6	0.7	-0.3	1.0	0.4
Ever had hysterectomy (womb removed)	0.6	0.7	2.8	0.4	-0.4	0.3	1.4	-0.6	-0.7	-1.2	0.8	-0.1	0.4	-0.4	-0.7	0.6	0.9	-0.1	1.0	-0.9	-1.7
Maternal smoking around birth	0.6	0.8	2.9	1.1	1.7	1.0	-0.6	0.9	-0.7	1.5	0.5	0.3	-0.1	0.6	0.8	1.2	0.7	-0.9	-1.3	-0.6	-0.4
High blood pressure	0.6	1.7	7.3	-1.1	-0.6	0.5	-0.3	2.7	-0.2	-0.3	-1.5	-1.8	0.8	-2.0	-0.6	-1.1	-1.5	1.5	-0.9	1.5	1.6
Waist circumference	0.6	2.3	6.4	-1.8	-1.4	-2.5	-0.9	0.7	1.3	-2.1	-1.9	-0.8	0.2	-1.4	-1.5	-1.6	-1.8	1.3	1.1	1.9	1.4
Qualifications: None of the above	0.6	1.3	4.4	0.9	0.6	1.0	0.4	-0.7	-0.8	1.6	0.7	1.1	-0.9	1.0	2.1	0.8	1.1	-1.6	-1.6	-1.8	-0.4
Hayfever/allergic rhinitis (self-reported)	0.6	0.7	2.2	-1.0	-0.8	-0.2	-1.0	-1.0	-0.2	-0.7	-0.7	-0.1	-1.2	-0.1	1.3	-1.3	-0.8	0.6	0.6	1.5	0.6
Weight	0.6	3.1	8.5	-1.9	-1.3	-2.9	-1.0	1.0	1.1	-2.4	-2.4	-1.2	0.7	-1.8	-2.1	-1.7	-2.0	1.8	1.4	2.0	1.4
Happiness	0.6	0.7	3.7	0.6	1.3	0.8	-0.9	1.9	0.9	0.5	0.2	1.2	-0.5	1.3	0.1	0.6	0.3	-0.9	-0.1	0.0	0.4
Neck or shoulder pain in last month	0.6	0.8	3.0	0.4	1.1	0.3	-0.9	0.7	0.8	0.2	-0.3	1.2	-1.5	1.6	1.7	0.2	0.3	-0.7	-0.9	0.2	0.9
Leg fat mass (right)	0.6	2.5	5.7	-1.5	-0.7	-2.4	-1.2	0.3	0.1	-1.6	-2.3	-1.8	1.3	-2.0	-1.6	-1.5	-1.9	1.7	1.1	2.0	1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.6	0.6	1.5	0.7	0.9	1.2	0.5	0.6	0.6	-0.5	0.9	0.9	-0.6	0.9	0.5	1.0	0.6	-1.1	-0.3	-0.9	-1.2
Loneliness, isolation	0.6	0.8	3.9	0.6	0.4	0.2	-0.4	2.0	-1.2	-1.0	0.5	-0.6	1.1	-0.9	-1.8	0.6	0.2	0.0	-0.5	-0.6	-1.1
Illnesses of father: None of the above (group 1)	0.6	0.8	5.2	-0.8	-1.0	-1.0	-2.3	-0.3	-0.7	-1.1	-1.3	0.0	-0.5	-0.0	0.3	-0.8	-0.7	0.3	0.8	0.6	0.7
Arm fat mass (left)	0.6	2.5	5.5	-1.5	-0.7	-2.4	-0.7	0.6	0.6	-1.9	-2.3	-1.6	0.8	-1.8	-1.5	-1.6	-2.0	1.7	0.7	2.2	1.5
Ever taken oral contraceptive pill	0.6	0.6	2.5	0.7	-0.0	0.1	1.0	-0.4	-1.1	0.2	0.3	-0.9	0.8	-0.5	-1.3	0.7	0.4	-0.9	-1.6	-0.8	-0.2
Hearing aid user	0.6	0.7	3.3	0.4	1.2	1.5	0.0	1.8	-0.3	-0.7	-0.5	-0.9	0.7	-0.4	0.0	-0.1	-0.6	0.9	-0.6	1.0	0.8
Eye problems/disorders: Glaucoma	0.6	0.7	3.4	0.8	1.1	1.8	0.0	1.3	-1.8	0.5	-0.2	-0.8	0.4	-0.2	-0.1	0.5	0.5	0.2	-0.7	-0.1	1.0
Fractured/broken bones in last 5 years	0.6	0.7	3.9	-0.1	0.3	0.2	-1.0	1.2	0.7	-2.0	-1.1	-0.8	0.1	-0.8	-1.2	-0.2	-0.6	-0.0	-1.1	0.7	0.1
Diastolic blood pressure, automated reading	0.6	1.8	4.0	2.0	2.0	1.7	1.6	1.6	-0.2	0.4	1.5	0.7	-0.6	1.4	0.6	1.6	1.7	-1.6	-1.4	-0.7	-0.5
Vascular/heart problems diagnosed by doctor	0.6	1.7	7.7	1.0	0.7	-0.3	0.2	-2.8	0.4	0.7	1.7	1.9	-0.4	2.0	0.7	1.0	1.2	-1.3	1.0	-1.4	-1.7
Crohns Disease (2017)	0.5	1.1	5.0	0.8	0.9	0.2	2.2	-0.3	1.4	-0.7	-0.1	0.4	-1.5	1.0	0.1	0.6	0.0	-1.6	-2.0	-0.6	-0.3
Reaction Time	0.5	1.0	3.0	0.1	0.2	-0.1	-1.4	-1.5	-0.5	1.3	0.8	1.5	-0.6	1.2	1.5	0.3	0.4	-0.5	1.7	-0.2	-0.9
Mean Putamen Volume	0.5	0.6	1.4	-1.0	-1.2	-1.0	-0.6	-1.0	-0.9	0.7	-0.5	-0.3	0.5	-0.7	-0.7	-0.5	-0.9	0.8	1.1	0.6	0.0
Relative age of first facial hair	0.5	1.1	2.1	1.3	1.4	0.2	1.5	0.6	0.8	1.0	1.1	0.9	-0.9	0.9	-0.1	1.2	1.4	-1.2	-0.6	-1.2	-1.4
Systolic blood pressure, automated reading	0.5	1.4	3.2	1.3	0.6	1.3	1.8	1.6	-0.2	-0.3	1.5	0.8	-0.7	1.0	0.3	1.2	1.4	-1.4	-1.8	-1.3	-0.5
Angina	0.5	0.7	5.8	0.1	-0.7	-0.2	1.1	0.3	0.2	-2.4	-0.1	-0.9	-0.4	-0.7	-1.5	0.5	0.5	-0.2	0.5	-0.2	-0.7
Medication for hormone replacement therapy	0.5	0.6	1.2	0.9	0.9	0.7	1.1	1.1	-0.4	-0.6	0.6	-0.7	-0.1	-0.0	-0.8	0.9	0.9	-0.6	-0.5	-0.7	-1.1
Medication: Metformin	0.5	0.7	4.9	-0.7	-1.2	-1.1	-0.5	0.0	-0.6	-0.5	-0.5	-0.8	0.8	-0.9	-2.2	-0.3	-0.4	0.3	0.4	0.1	0.2
Average weekly fortified wine intake	0.5	0.6	2.7	0.4	0.2	-0.2	-0.3	0.1	-0.2	-0.8	1.3	-0.2	0.2	-0.2	-1.6	0.7	0.7	0.1	1.4	-0.5	-1.3
Supplements: Glucosamine	0.5	0.6	2.5	0.4	0.3	-0.0	1.6	0.3	-0.3	-0.3	0.8	1.4	-0.8	0.9	-0.4	0.8	0.7	-1.0	0.2	-1.0	-0.7
Medication: Atenolol	0.5	0.6	1.6	-0.3	0.0	1.0	1.3	1.1	1.1	0.2	-0.3	0.0	-1.2	0.1	1.1	-0.5	-0.5	-0.1	-1.2	0.5	1.1
Medication: Ramipril	0.5	0.7	1.4	-1.0	-0.7	-0.3	0.6	0.7	-0.9	-1.2	-1.0	-0.6	-0.4	-0.8	-0.2	-1.1	-0.7	0.9	0.5	0.9	1.2
Noisy workplace	0.5	0.7	1.7	0.8	0.7	-0.6	-1.0	-0.6	0.2	1.3	0.9	1.2	-0.2	1.0	0.5	0.7	0.7	-0.7	0.9	-0.8	-1.1
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.6	0.5	0.2	0.3	0.9	-0.0	0.5	-0.4	1.0	0.9	-1.6	0.9	0.7	0.6	1.0	-0.7	0.3	-0.9	-0.7
Medication: Lansoprazole	0.5	0.6	1.9	-0.2	-0.4	0.8	0.7	0.7	-1.0	-1.0	0.2	-1.1	0.6	-1.1	-0.9	-0.1	-0.5	-0.2	-1.4	-0.8	-0.5
Birth weight of first child	0.5	1.0	2.4	-1.1	-0.9	-1.1	-1.0	-0.8	-0.9	0.4	-1.0	-0.8	1.0	-1.1	-0.8	-1.2	-0.9	1.6	1.2	0.7	0.6
Pulse wave reflection index	0.5	0.7	1.9	-1.0	-1.0	-0.6	-0.7	-0.2	-0.4	-0.6	-0.7	-0.6	-0.5	-0.6	0.9	-1.0	-0.7	1.4	1.2	1.0	0.2
Chronic bronchitis/emphysema (mother)	0.5	0.5	1.7	0.8	0.6	0.6	-0.1	-0.5	-1.1	0.2	0.3	-1.3	1.2	-0.7	-1.2	0.4	-0.2	0.2	-0.0	0.7	-0.8
Worry too long after embarrassment	0.5	0.8	2.0	1.1	1.4	0.7	0.7	1.2	0.1	1.3	1.1	0.8	-0.3	0.7	0.3	1.1	1.1	-0.4	1.1	-0.1	-0.8
Health satisfaction	0.5	0.6	3.0	0.8	1.0	0.4	-0.3	0.5	1.7	1.1	1.0	0.8	-0.2	1.1	0.2	0.6	0.6	-1.1	-0.4	-0.5	-0.0
Angina (self-reported)	0.5	0.6	4.6	0.1	-0.6	-0.1	1.2	0.4	0.1	-2.1	-0.1	-0.8	-0.5	-0.6	-1.4	0.6	0.5	-0.3	0.5	-0.3	-0.7
Medication: Omeprazole	0.5	0.6	1.8	0.4	0.4	-0.7	0.9	-0.3	1.0	0.7	0.2	1.0	-1.2	1.2	0.5	0.9	0.8	-1.3	0.4	-0.2	-0.6
Medication: Seretide 50 evohaler	0.5	0.6	3.2	0.4	-0.3	0.2	1.2	-0.6	-0.2	-0.3	1.3	0.4	0.1	0.1	0.0	0.7	1.0	-0.8	0.5	-0.9	-1.8
Illnesses of father: Heart disease	0.5	0.7	2.3	-0.4	-0.6	-0.9	1.0	-0.3	-0.7	0.1	0.5	-1.3	1.4	-1.1	-1.5	-0.1	-0.5	0.7	0.5	0.2	-1.2
Average weekly red wine intake	0.5	0.7	2.7	0.3	1.0	1.5	-0.8	1.1	-0.2	-0.4	-0.7	-1.0	0.7	-0.5	-0.6	-0.0	-0.7	0.4	-1.6	0.5	0.9
Long-standing illness, disability or infirmity	0.5	0.8	4.8	0.4	0.9	1.8	0.8	2.2	-0.0	1.0	-0.7	-0.1	-0.2	-0.2	-0.8	0.4	0.3	-0.1	-1.0	-0.2	0.7
Medication: Gliclazide	0.5	0.6	3.0	0.2	0.0	-0.9	0.0	-1.4	0.2	1.2	0.5	-0.1	0.6	-0.2	-1.7	0.6	0.7	-0.6	-0.1	-1.1	-0.6
Number of self-reported non-cancer illnesses	0.5	0.8	3.4	-1.1	-1.0	0.3	0.1	1.8	-0.5	-1.8	-0.9	-0.3	-0.9	-1.2	-0.4	-0.9	-0.7	0.2	-0.8	-0.0	0.4
Medication: Blood pressure	0.5	1.0	2.9	-0.7	-0.2	0.3	-0.7	1.0	0.3	0.6	-1.4	-0.9	1.2	-1.2	-0.5	-0.8	-1.5	0.4	-1.6	0.7	1.7
Medication: Atorvastatin	0.5	0.6	4.0	-0.1	-0.5	0.2	0.5	1.4	-1.2	-1.0	-0.1	-0.7	-0.1	-0.9	-2.0	0.1	-0.2	0.1	-0.8	-0.2	-0.3
Alcohol drinker status: Never	0.5	0.6	2.2	-1.2	-0.6	-0.4	-0.6	-1.0	-0.6	0.8	-0.9	-0.1	-0.2	-0.6	0.7	-1.2	-1.5	0.7	-0.4	0.3	0.7
Irritability	0.5	0.9	5.2	-0.6	-0.4	-0.6	-0.3	1.0	0.3	-0.3	-0.9	-1.2	0.9	-1.9	-2.3	-0.4	-0.7	0.8	-0.4	0.3	0.6
Ever depressed for a whole week	0.5	0.6	3.1	0.6	1.2	1.0	0.4	1.8	0.1	1.0	0.3	0.1	0.3	-0.1	0.1	0.8	0.7	-0.2	-0.4	-1.2	-0.7
Unable to work because of sickness or disability	0.5	0.6	2.4	-0.2	0.0	0.9	0.6	1.5	-0.8	1.2	-0.8	-0.7	0.2	-0.8	-0.2	-0.4	-0.6	0.5	-0.1	1.3	0.5
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	2.4	0.1	0.1	-0.6	0.8	-0.1	1.6	1.6	0.3	0.7	-0.9	1.0	0.3	0.7	0.6	-1.2	0.4	-0.1	-0.3
Basal cell carcinoma (self-reported)	0.5	0.6	5.5	-0.6	-0.4	-0.7	0.3	-0.1	0.7	-2.4	-0.4	-0.7	0.6	-0.4	0.1	-0.8	-0.9	0.8	0.1	0.8	0.1
Triglycerides	0.4	0.7	2.4	0.1	-0.2	-0.4	-0.4	-1.5	0.7	0.2	0.3	1.4	-0.9	1.1	1.3	0.4	1.0	-1.3	-0.1	-0.6	-0.1
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.4	-0.3	0.1	0.3	-0.9	0.9	0.9	-0.8	-0.6	-0.3	0.1	-0.8	0.4	-0.3	-0.5	1.2	0.9	1.1	0.7
Heel T-Score	0.4	3.3	8.3	0.9	0.2	-0.0	0.1	-0.2	1.7	2.9	2.5	2.4	-2.2	2.2	1.0	2.0	2.7	-1.4	2.5	-1.2	-1.7
Average weekly spirits intake	0.4	0.5	2.3	-0.3	-0.5	-1.5	-0.3	-1.5	-0.3	-0.5	-0.1	0.9	-0.3	0.2	-0.1	-0.2	-0.1	0.1	1.5	0.2	-0.3
Sensitivity / hurt feelings	0.4	0.8	2.3	0.5	0.5	1.3	1.5	1.1	1.0	1.3	0.7	0.3	0.3	-0.0	-0.5	0.5	0.6	-0.5	-1.2	-1.3	-0.5
Severe depression (siblings)	0.4	0.4	3.6	0.1	0.3	0.7	0.6	1.9	-0.9	0.4	-0.3	0.4	-0.7	0.4	0.3	0.1	0.8	-0.1	0.7	-0.1	0.6
Leg fat-free mass (left)	0.4	2.0	8.0	-1.5	-1.1	-2.8	-0.3	0.6	2.7	-1.6	-1.5	1.4	-1.5	0.3	-0.3	-1.1	-0.7	0.4	2.0	1.0	0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	0.4	0.5	2.4	-0.0	0.1	-0.7	0.1	-1.3	0.9	1.6	0.3	1.3	-0.8	0.9	1.0	-0.2	-0.0	-0.5	0.2	0.2	0.1
Age when periods started (menarche)	0.4	1.0	3.6	-0.6	-0.8	0.7	-0.9	0.7	-1.9	0.2	-0.3	-1.2	0.7	-1.0	0.1	-1.2	-1.3	1.4	0.0	1.4	1.0
Chronic bronchitis/emphysema (father)	0.4	0.5	2.0	0.8	0.7	1.0	0.8	-0.1	1.4	-0.2	0.2	0.2	-0.2	0.3	0.5	0.4	0.8	-0.8	-1.1	-0.1	0.5
Leg predicted mass (left)	0.4	1.9	7.8	-1.4	-1.0	-2.7	-0.3	0.6	2.8	-1.5	-1.4	1.5	-1.6	0.4	-0.2	-1.0	-0.6	0.3	2.1	1.0	0.4
Past tobacco smoking	0.4	0.6	2.7	0.4	-0.1	0.9	0.8	-0.8	-1.6	-0.1	0.5	-0.8	0.8	-0.3	0.4	0.3	0.2	-0.3	-1.2	-1.2	-1.3
Nervous feelings	0.4	0.7	1.7	1.1	1.1	1.2	0.6	1.3	-0.4	-0.6	0.8	0.1	0.2	-0.2	-1.1	1.0	0.9	-0.5	-0.7	-1.0	-1.1
Hearing difficulty/problems with background noise	0.4	0.7	2.2	-0.6	-0.1	-0.3	-1.1	0.7	1.4	0.2	-0.3	-0.5	0.3	-0.3	0.4	-0.8	-0.7	1.4	1.1	1.5	0.9
Mouth/teeth dental problems	0.4	0.6	4.0	0.5	0.4	0.5	2.0	1.0	-1.3	0.5	0.4	-0.6	0.3	-0.2	-0.4	0.6	0.2	0.3	0.3	-0.2	-1.1
Diabetes (self-reported)	0.4	0.6	3.1	-1.0	-1.1	-1.0	0.1	-0.3	0.5	-0.2	-0.7	-0.6	0.3	-0.8	-1.7	-0.7	-0.8	0.0	-0.8	0.2	0.7
Fluid intelligence score	0.4	0.7	5.2	-1.0	-0.9	-0.0	-0.8	0.2	2.3	-0.9	-0.7	0.4	-0.5	0.1	-0.4	-0.8	-0.1	0.2	1.2	0.9	0.9
Time employed in main current job	0.4	0.5	1.8	-0.7	-0.8	0.5	-0.4	-0.2	-0.1	1.0	-0.8	-0.9	0.8	-0.4	0.4	-0.7	-0.6	0.5	-0.4	0.4	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.7	2.1	-0.6	-0.2	-0.3	-1.5	0.7	1.4	1.1	-0.2	-0.3	0.1	-0.4	-0.1	-0.7	-0.7	0.9	1.1	1.4	0.4
Hair/balding pattern: Pattern 3	0.4	0.6	3.8	0.1	-0.0	0.6	0.1	0.4	1.3	0.4	0.1	2.0	-1.1	1.2	1.4	0.2	0.3	-0.5	0.5	-0.4	-0.3
Prospective memory result	0.4	0.5	2.4	-0.5	-0.8	0.2	-0.1	-0.6	-0.7	0.2	-0.0	-0.4	1.3	-0.7	-0.6	-0.4	-0.6	1.2	1.5	0.2	-0.2
Pulse wave Arterial Stiffness index	0.4	0.4	3.7	-0.3	-0.8	-0.3	0.0	0.3	0.7	-0.7	0.5	-0.2	-0.3	-0.4	0.1	-0.2	0.2	0.8	1.9	0.7	-0.5
Exposure to tobacco smoke at home	0.4	0.5	2.0	0.3	0.5	-0.7	-0.4	-0.6	1.0	-0.1	-0.1	0.9	-1.0	1.1	1.4	-0.2	0.0	-0.5	-0.8	-0.1	0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	6.0	-0.1	0.8	1.3	-0.4	2.5	0.3	0.6	-0.6	-0.3	0.1	-0.3	-0.3	-0.1	-0.5	0.7	-0.2	0.1	0.0
Glaucoma (self-reported)	0.4	0.4	1.5	0.3	0.7	1.2	-0.8	0.1	-1.1	0.5	-0.5	-0.2	-0.6	0.4	1.1	0.0	0.1	-0.1	-0.7	0.1	1.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.4	0.5	1.5	0.4	0.2	-0.1	0.8	0.9	0.2	0.3	1.0	0.9	-1.0	0.6	-0.3	0.8	0.9	-0.4	1.0	-0.4	-1.2
Medication for pain relief, constipation, heartburn	0.4	0.7	4.0	-0.4	-0.5	0.2	-0.2	-1.1	0.5	1.5	-0.3	0.9	-0.5	1.0	2.0	-0.6	-0.3	-0.2	-1.0	0.2	1.2
Alcohol intake frequency.	0.4	1.0	2.8	-0.7	-0.6	-0.8	-1.1	0.4	0.3	-0.4	-0.3	-1.4	1.4	-1.6	-1.7	-0.6	-1.0	1.4	1.1	0.9	-0.2
Age at last live birth	0.4	0.5	3.9	0.5	0.3	0.0	2.0	0.6	-0.4	1.5	0.5	0.2	-0.0	0.4	0.1	0.6	1.0	-0.3	0.1	-0.7	-0.7
Commuting to job workplace: Car/motor vehicle	0.4	0.4	3.0	-0.2	-0.2	-0.4	-0.2	0.7	-1.4	-1.7	-0.5	-0.6	0.5	-0.5	-0.3	-0.2	-0.1	-0.1	-0.1	0.3	0.7
Ever had bowel cancer screening	0.4	0.4	2.8	-0.3	-0.1	-0.1	-0.6	0.4	0.1	-1.7	-1.3	-0.6	-0.1	-0.3	0.0	-0.5	-0.3	0.3	-0.0	0.9	1.1
Diabetes diagnosed by doctor	0.4	0.6	2.4	-0.9	-0.9	-0.9	0.1	-0.2	0.5	0.2	-0.6	-0.8	0.7	-1.0	-1.5	-0.7	-0.9	0.1	-1.0	0.4	0.8
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.3	0.9	0.8	0.2	0.2	-0.1	0.7	0.8	0.6	0.7	-0.7	1.1	0.4	0.6	0.9	-1.0	-0.0	-0.1	-0.6
Commuting to job workplace: Walk	0.4	0.5	2.5	-0.8	-0.9	-1.0	0.1	-0.6	1.6	0.6	0.1	-0.1	-0.3	-0.3	0.1	-0.8	-1.0	0.6	0.5	0.6	0.1
Average weekly champagne plus white wine intake	0.4	0.5	2.8	-1.2	-1.1	-0.2	1.0	-1.7	1.0	-0.4	-0.5	0.1	-0.2	-0.3	0.3	-0.8	-0.7	0.4	-0.3	-0.1	0.4
Medication: Bendroflumethiazide	0.4	0.6	2.3	-0.7	-0.7	-0.4	-0.6	0.3	-0.7	0.6	-0.7	-0.9	0.9	-0.9	-0.4	-1.0	-0.9	0.3	-1.5	-0.1	1.3
Ever smoked	0.4	0.7	4.8	0.5	0.7	-0.9	-0.8	0.5	2.2	0.7	0.5	1.3	-0.7	0.7	-0.6	0.5	0.9	-0.6	0.8	0.1	0.2
Average weekly beer plus cider intake	0.4	0.6	1.7	0.4	0.8	-0.6	0.0	-0.4	0.9	-0.6	-0.7	0.8	-1.3	0.6	0.1	0.6	0.4	-1.1	-1.3	-0.9	-0.0
Risk taking	0.4	0.6	2.4	0.0	0.3	-0.6	0.7	-0.6	0.7	0.5	-0.5	1.1	-1.6	0.8	1.3	0.2	0.2	-1.1	-0.9	-0.4	0.2
Commuting to job workplace: Cycle	0.4	0.5	1.7	0.5	0.4	0.1	0.5	-0.8	1.3	0.8	0.4	0.9	-0.2	1.0	-0.3	0.8	0.9	-0.4	0.7	-0.2	-0.5
Pain experienced in last month	0.4	0.7	2.0	-0.6	-0.5	0.2	-0.2	-0.7	-0.9	0.7	-1.1	-1.4	1.4	-1.2	-0.1	-0.8	-0.8	0.6	-0.8	0.5	1.1
Alcohol drinker status: Previous	0.4	0.5	2.1	0.1	-0.2	0.0	-0.3	0.6	-1.4	-0.5	0.2	-0.5	0.7	-0.7	-1.2	0.3	0.0	1.0	1.2	0.5	-0.6
Depression (Nagel 2018)	0.3	0.4	1.6	-0.4	-0.4	-1.1	0.1	-0.9	0.1	1.2	-0.1	0.5	-0.0	0.0	0.2	-0.5	-0.4	0.2	1.3	0.8	-0.4
Alzheimer’s Disease (including proxy)	0.3	0.5	1.5	-0.7	0.0	-0.8	-0.7	0.6	0.4	0.4	-0.8	0.9	-0.4	0.5	1.2	-0.7	-0.6	0.5	0.4	0.7	1.2
Primary Biliary Cirrhosis	0.3	0.4	1.8	0.3	0.6	0.5	-0.1	-1.3	1.3	-0.5	-0.1	1.0	-0.8	0.4	0.4	0.2	-0.0	-0.8	-0.7	-0.2	-0.2
Blood Eosinophil Count	0.3	2.7	7.3	-1.1	-1.4	-1.7	-2.7	-1.2	-2.7	1.8	-1.9	-1.8	0.9	-2.1	0.5	-1.5	-0.5	1.1	-0.2	1.2	2.3
Blood Platelet Count	0.3	4.0	23.1	0.9	0.8	0.0	2.8	1.8	4.8	0.8	1.1	1.6	-3.6	1.8	1.5	1.1	2.1	-1.9	-1.2	-1.3	-0.2
Waist Hip Ratio (WHR)	0.3	1.1	3.6	0.8	0.5	0.4	-0.2	0.3	1.3	-0.6	1.1	1.7	-1.9	1.6	0.8	1.0	1.3	-1.8	-0.1	-0.7	-0.2
Systolic Blood Pressure	0.3	1.6	14.2	0.8	0.5	2.4	1.5	3.8	-0.1	-0.5	1.1	-0.7	0.2	-0.7	0.4	0.5	0.6	0.0	-1.7	-0.2	0.6
Smoking Status	0.3	0.7	3.0	-0.0	0.1	-0.7	0.6	0.4	1.4	1.7	-0.5	1.0	-1.2	0.8	0.9	-0.1	0.2	-1.0	-0.5	0.3	1.1
Allergy or Eczema	0.3	0.8	4.0	1.0	0.8	1.0	0.3	1.4	0.4	-2.0	0.7	-0.2	-0.9	0.5	0.7	0.7	0.8	-0.6	-1.0	-0.5	-0.9
Respiratory disease	0.3	0.7	2.5	-0.6	-0.6	-0.3	-1.6	0.9	-0.3	-0.3	-0.8	-1.0	0.8	-1.1	-1.1	-0.9	-0.9	1.0	-0.4	0.9	0.9
Frequency of depressed mood in last 2 weeks	0.3	0.4	1.8	0.2	0.5	-0.6	0.4	-0.1	0.7	1.3	0.5	1.0	-0.7	0.7	0.9	0.1	0.0	-0.3	1.0	0.3	-0.6
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	2.6	-0.3	-0.2	0.1	-1.6	0.5	-0.3	-0.1	-0.8	-0.4	0.4	-0.3	-0.6	-0.3	-0.7	-0.0	-0.8	0.5	0.8
Medication: Co-codamol	0.3	0.4	2.5	-0.3	-0.3	-0.3	1.1	0.3	-0.4	-1.1	0.6	-0.2	0.1	-0.7	-0.5	0.2	0.2	-0.3	0.0	-0.6	-1.6
Hayfever, allergic rhinitis or eczema	0.3	0.6	3.8	0.6	0.7	0.6	0.5	-0.1	0.4	-2.0	0.2	0.0	-0.8	0.5	1.4	0.4	0.3	-0.7	-0.9	-0.2	-0.6
Multivitamins +/- minerals	0.3	0.4	2.3	-0.2	-0.4	-0.6	0.7	-1.1	1.5	0.4	0.3	1.0	-0.4	0.6	-0.0	-0.0	-0.0	-0.8	0.9	-0.1	-0.2
Body mass index (BMI)	0.3	1.1	6.1	-1.0	-0.3	-2.5	-0.5	-1.0	1.4	-0.4	-1.8	0.7	-1.0	0.4	1.0	-0.8	-0.9	-0.0	0.7	1.1	1.1
Alcohol usually taken with meals	0.3	0.5	2.6	-0.1	-0.5	0.6	0.3	0.3	-0.8	0.1	0.6	-0.7	1.6	-0.6	-1.4	-0.0	-0.0	1.0	0.5	-0.4	-0.4
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	2.3	0.1	0.4	0.1	-0.5	0.9	-0.3	1.5	0.5	0.6	0.8	0.2	-0.4	0.3	0.4	0.2	1.0	-0.4	-0.7
Trunk fat-free mass	0.3	1.9	6.7	-1.1	-1.1	-2.4	0.2	1.0	2.6	-1.3	-0.4	2.2	-2.1	1.2	0.1	-0.6	-0.1	-0.1	2.2	0.4	-0.2
Alcohol intake versus 10 years previously	0.3	0.5	1.9	-0.1	-0.1	0.2	-1.3	-0.2	0.3	1.0	-0.6	-1.0	1.1	-0.8	-1.4	-0.0	-0.1	0.2	0.2	0.5	0.8
Mouth/teeth dental problems: Dentures	0.3	0.5	5.0	0.4	0.5	-0.0	-2.2	0.0	-0.5	0.1	0.5	0.7	0.2	0.5	-0.4	0.5	0.8	-0.6	0.2	-0.9	-0.6
Asthma	0.3	0.6	2.4	-0.6	-1.2	-0.0	-1.3	1.4	-0.0	-1.6	0.5	-0.3	0.4	-0.8	-1.0	-0.8	-0.3	0.6	0.0	0.3	-0.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.9	0.9	1.1	0.3	0.3	-0.1	-0.3	-0.5	0.7	-0.4	0.7	-0.2	-0.4	0.7	0.3	-0.2	-0.5	-0.8	-1.4
Trunk predicted mass	0.3	1.8	6.2	-1.1	-1.1	-2.3	0.3	1.1	2.5	-1.2	-0.4	2.2	-2.0	1.2	0.1	-0.5	-0.0	-0.1	2.3	0.4	-0.2
Length of working week for main job	0.3	0.3	1.1	0.1	0.5	0.3	0.1	0.6	0.4	-0.3	-0.6	0.3	-0.8	0.4	1.0	-0.2	-0.1	-0.3	-1.0	0.1	0.8
Tense / ‘highly strung’	0.3	0.4	2.1	-0.6	-0.5	-0.7	-0.6	-1.0	-0.1	0.4	-0.2	0.9	-0.6	0.2	1.4	-0.6	-0.2	0.1	1.1	0.2	-0.0
Loud music exposure frequency	0.3	0.4	1.5	0.1	0.2	0.6	-0.3	0.3	-0.7	-0.2	-0.1	-1.2	1.1	-0.9	-0.5	-0.1	-0.5	0.5	-1.1	-0.2	-0.2
Headache pain in last month	0.3	0.5	1.8	0.8	1.0	0.8	0.3	1.3	0.6	-0.9	0.2	0.6	-1.3	0.8	0.3	0.6	0.4	-0.7	-0.6	-0.0	-0.4
Medication: Amlodipine	0.3	0.4	2.9	-0.4	-0.5	0.8	0.1	0.1	0.2	-0.7	-0.2	-0.4	0.1	-0.7	-0.3	-0.3	-0.7	-0.2	-1.7	-0.6	0.4
High blood pressure (siblings)	0.3	0.4	2.5	0.1	0.1	0.3	-0.8	1.2	0.3	-1.6	-0.3	-0.4	-0.9	0.4	0.4	-0.1	0.0	0.0	-0.1	0.9	0.5
Arm fat-free mass (right)	0.3	1.3	5.5	-0.7	-0.6	-2.4	0.5	0.4	2.1	-0.7	-0.3	2.0	-1.8	1.2	0.3	-0.2	0.0	-0.4	1.9	0.3	-0.5
Age at first live birth	0.3	0.6	2.6	-0.1	-0.2	-0.5	0.6	0.7	-0.9	0.6	0.3	-0.9	1.3	-0.8	-1.6	0.1	0.5	1.0	1.0	-0.3	-0.7
Pulse wave peak to peak time	0.3	0.4	3.4	0.1	0.6	0.1	-0.3	-0.1	-0.7	0.4	-0.7	-0.1	0.6	0.0	-0.4	-0.0	-0.5	-0.4	-1.8	-0.4	0.7
Shortness of breath walking on level ground	0.3	0.4	2.8	-0.1	-0.4	0.3	-1.2	-0.6	-0.8	0.3	0.3	0.8	-0.1	0.2	0.4	0.1	0.1	-0.1	1.7	0.5	-0.4
Arm predicted mass (right)	0.3	1.3	5.1	-0.8	-0.8	-2.2	0.5	0.7	1.9	-1.1	-0.3	1.9	-1.6	1.0	0.1	-0.2	-0.0	-0.3	2.0	0.2	-0.5
Chest pain or discomfort	0.3	0.4	2.2	-0.1	0.1	-0.6	0.1	-0.3	-0.9	-0.1	-0.5	-1.0	1.0	-1.5	-0.9	-0.2	-0.4	0.4	-0.1	0.3	0.2
Illness, injury, bereavement, stress in last 2 years	0.3	0.3	0.9	-0.2	-0.1	0.9	0.7	0.9	0.0	-0.6	-0.7	-0.1	0.5	-0.3	-0.6	-0.2	-0.1	0.1	-1.0	-0.0	0.8
Whole body fat-free mass	0.3	1.8	7.0	-1.1	-1.0	-2.6	0.1	0.7	2.6	-1.2	-0.8	2.0	-1.9	0.9	-0.1	-0.6	-0.2	-0.0	2.2	0.6	-0.0
Leg fat-free mass (right)	0.3	1.5	7.0	-1.1	-0.8	-2.3	0.1	0.7	2.6	-1.2	-1.1	1.6	-1.7	0.6	-0.1	-0.7	-0.4	0.1	1.8	0.6	0.2
Back pain experienced in last month	0.3	0.4	1.6	-0.4	-0.8	-0.8	0.4	-0.1	-0.9	-1.3	0.0	0.0	-0.4	-0.5	-1.1	-0.1	-0.4	0.1	0.8	-0.0	-0.7
Breast cancer (self-reported)	0.3	0.3	1.3	-0.1	0.0	-1.1	-0.3	-0.9	0.9	0.4	-0.2	0.4	-0.3	0.5	-0.3	0.1	0.1	-0.8	-1.0	-0.5	-0.4
Asthma (self-reported)	0.3	0.6	2.7	-0.3	-0.8	0.2	-1.1	1.6	-0.3	-1.6	0.7	-0.4	0.5	-0.9	-1.1	-0.6	-0.1	0.5	-0.2	0.1	-0.4
Whole body water mass	0.3	1.8	7.3	-1.1	-0.9	-2.5	0.1	0.8	2.7	-1.3	-0.7	2.0	-1.9	0.9	-0.0	-0.6	-0.2	-0.1	2.1	0.6	-0.0
Leg predicted mass (right)	0.3	1.5	6.8	-1.1	-0.8	-2.3	0.2	0.7	2.6	-1.2	-1.1	1.6	-1.7	0.6	-0.1	-0.7	-0.4	0.1	1.7	0.6	0.2
Miserableness	0.3	0.6	1.7	0.3	0.4	0.2	-0.9	0.5	0.9	-0.3	0.4	1.2	-1.3	0.8	0.6	0.4	1.1	-0.6	1.2	-0.1	-0.8
Commuting to job workplace: Public transport	0.3	0.4	1.4	-0.7	-0.6	0.1	-0.1	-0.1	-0.1	-0.8	-0.4	-0.4	-0.0	-0.2	0.7	-0.9	-0.8	0.8	0.2	1.2	0.8
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.3	0.5	0.6	0.7	0.0	0.4	0.4	0.9	1.1	0.9	-0.4	0.5	-0.0	0.6	0.3	-0.4	0.6	-0.6	-1.0
Basal metabolic rate	0.3	1.6	7.1	-1.3	-1.0	-2.7	-0.2	0.9	2.3	-1.6	-1.2	1.1	-1.2	0.2	-0.6	-0.9	-0.7	0.5	1.9	1.0	0.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.7	0.0	-0.1	-0.5	1.1	0.6	0.5	0.1	0.4	0.2	-0.6	0.3	-0.3	0.4	0.7	-0.4	0.5	-0.8	-1.3
Bipolar Disorder or Schizophrenia	0.2	0.4	3.0	-0.3	-0.1	-0.2	0.1	1.7	1.2	-0.4	-0.1	-0.2	-0.8	0.2	0.2	-0.1	0.1	0.4	0.6	0.8	-0.3
Worry (Nagel 2018)	0.2	0.4	1.6	-0.8	-0.3	-0.0	-0.8	-0.0	0.3	0.5	-1.3	-0.2	0.5	-0.7	-0.1	-0.9	-0.9	0.6	-0.4	0.4	0.9
Bipolar Disorder (2011)	0.2	0.2	1.7	-0.1	-0.3	0.3	0.1	0.7	1.3	-0.7	-0.2	0.0	0.3	-0.4	-0.4	0.2	0.1	0.3	0.6	0.1	-0.1
LDL Cholesterol	0.2	0.3	3.0	-0.6	-0.5	-0.0	-0.6	-1.7	-0.5	-0.5	-0.6	-0.2	0.2	-0.6	0.2	-0.7	-0.4	0.5	0.1	0.3	0.2
Neuroticism (2016)	0.2	0.3	3.2	0.1	0.4	0.6	-0.1	1.8	-0.3	-0.0	0.2	0.1	-0.5	0.0	-0.3	0.2	0.3	0.4	0.6	0.1	0.4
BMI	0.2	1.1	3.1	-0.2	0.4	-1.5	0.4	-0.9	1.7	0.2	-1.1	1.8	-1.5	1.6	1.4	-0.1	-0.1	-0.9	0.1	0.6	0.8
Neuroticism	0.2	0.5	1.5	-0.6	-0.3	-0.4	-0.2	-0.3	-0.1	0.6	-0.9	-0.5	1.0	-1.2	-1.2	-0.7	-0.7	0.8	0.0	0.6	0.5
Hearing difficulty/problems: Yes	0.2	0.3	1.0	0.1	0.3	-0.4	-0.8	0.6	1.0	0.2	0.6	-0.3	-0.5	0.5	0.9	-0.2	-0.1	0.5	0.1	0.4	-0.2
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	1.3	-0.3	-0.3	1.1	0.5	1.0	0.1	-0.5	-0.3	-0.6	0.3	-0.9	-0.7	-0.2	-0.3	0.2	-0.8	-0.3	-0.2
Ever used hormone-replacement therapy (HRT)	0.2	0.3	0.8	0.2	0.2	-0.7	0.9	0.1	-0.2	0.9	-0.0	-0.4	0.6	-0.4	-0.7	0.2	0.1	-0.6	-0.9	-0.9	-0.7
Townsend deprivation index at recruitment	0.2	0.3	0.9	0.6	0.5	-0.2	0.8	-0.5	-0.5	-0.1	0.5	0.5	-0.5	0.5	0.1	0.5	0.1	-0.9	-0.6	-0.8	-1.0
Fed-up feelings	0.2	0.4	1.5	0.9	0.8	0.1	-0.1	0.5	-0.7	1.2	0.6	0.4	0.5	0.2	-0.5	0.8	0.7	-0.5	-0.4	-0.7	-0.8
Relative age voice broke	0.2	0.3	1.3	0.3	-0.1	-0.9	0.2	-0.9	0.6	1.1	0.5	0.3	-0.8	0.4	-0.3	0.1	0.6	-0.3	0.6	-0.1	-1.0
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.3	1.0	0.5	0.1	0.3	0.3	1.0	-0.8	0.4	0.6	-0.5	0.8	-0.3	-0.8	0.5	0.8	0.4	0.8	0.1	-0.6
Serious illness, injury or assault to yourself	0.2	0.3	1.8	-0.4	0.1	-0.3	-0.6	-0.1	0.6	0.7	-0.8	-0.1	-0.3	0.1	0.4	-0.4	-0.6	0.1	-0.7	0.4	1.3
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	1.8	0.1	-0.4	-1.1	0.3	-0.8	-0.4	0.4	0.9	0.6	0.3	-0.1	0.1	0.1	-0.2	-0.3	0.4	-0.3	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	1.7	0.4	-0.3	-0.3	0.4	-0.5	0.1	0.8	1.1	0.1	0.3	0.3	-0.3	0.6	0.9	0.0	1.3	-0.2	-1.2
Financial difficulties in last 2 years	0.2	0.2	0.8	0.4	0.8	0.4	0.2	-0.3	0.9	0.5	0.3	0.1	-0.3	0.1	-0.2	0.2	0.2	-0.7	-0.6	-0.4	-0.6
Allergy	0.2	0.5	2.1	-0.8	-0.6	-1.0	-0.1	-0.8	-0.3	1.4	-0.7	-0.1	0.6	-0.4	-0.6	-0.4	-0.3	0.7	1.2	0.4	1.0
Worrier / anxious feelings	0.2	0.4	2.3	0.4	0.8	1.5	0.6	1.4	0.5	0.2	0.1	0.1	0.4	-0.1	-0.3	0.4	0.2	0.1	-0.8	-0.5	-0.0
Exposure to tobacco smoke outside home	0.2	0.2	1.2	0.3	0.5	0.8	-0.0	0.8	0.4	0.2	-0.7	-0.3	0.0	-0.2	0.3	0.0	0.0	-0.1	-1.1	0.2	0.8
Number of full brothers	0.2	0.2	1.5	0.7	0.4	0.0	-0.3	0.3	-1.2	0.2	0.4	-0.7	0.2	0.1	-0.1	0.3	0.2	-0.2	-0.4	-0.3	-0.2
Qualifications: College or University degree	0.2	0.7	2.0	-0.6	-0.4	-0.4	0.5	0.7	0.6	-0.2	-0.3	-0.6	1.1	-1.1	-1.3	-0.4	-0.8	1.3	1.4	1.3	0.2
Mouth/teeth dental problems: Loose teeth	0.2	0.2	0.7	-0.5	-0.7	-0.2	-0.6	-0.1	-0.0	0.0	-0.2	0.1	-0.7	0.3	0.5	-0.7	-0.5	0.1	-0.4	0.4	0.8
Medication: Allopurinol	0.2	0.3	2.4	-0.5	-0.4	-1.0	1.5	-0.3	0.1	-0.1	-0.7	0.2	-0.1	-0.5	-0.2	-0.4	-0.5	0.2	0.4	0.4	0.7
Heart disease (mother)	0.2	0.3	1.7	-0.0	-0.0	0.2	-1.3	-0.2	0.1	-1.1	-0.3	-0.4	0.7	-0.2	0.3	-0.2	-0.5	0.0	0.0	0.5	0.4
Pulse rate, automated reading	0.2	0.6	1.9	-0.7	-0.2	-1.1	-0.5	-0.8	1.2	-0.2	-1.0	-0.0	0.5	0.2	0.9	-0.7	-0.8	0.0	-0.2	1.0	1.4
Number of full sisters	0.2	0.2	0.8	0.2	-0.3	-0.9	0.4	-0.8	0.0	-0.2	0.3	0.4	-0.2	0.5	-0.2	0.3	0.4	-0.3	0.3	-0.2	-0.7
Suffer from ‘nerves’	0.2	0.3	1.6	-0.3	-0.3	0.0	0.3	0.3	0.3	1.1	0.0	-0.1	0.2	-0.5	-1.3	0.0	-0.1	0.2	-0.0	-0.7	-0.7
Overall health rating	0.2	0.4	1.0	-0.8	-1.0	-0.6	-0.8	0.7	0.4	0.1	-0.7	0.1	-0.4	-0.6	0.0	-0.7	-0.6	0.0	0.2	0.6	0.9
Mouth/teeth dental problems: Mouth ulcers	0.2	0.4	1.9	-0.1	0.2	0.5	0.9	-0.3	0.8	0.1	-1.0	-0.0	-0.2	-0.2	0.6	-0.3	-0.3	-0.2	-1.0	0.6	1.4
Arm fat-free mass (left)	0.2	1.2	5.4	-0.7	-0.6	-2.3	0.1	0.6	1.9	-1.0	-0.4	1.8	-1.6	1.0	0.1	-0.3	-0.1	-0.3	1.6	0.2	-0.3
Arm predicted mass (left)	0.2	1.2	6.1	-0.8	-0.7	-2.5	0.1	0.7	2.0	-0.7	-0.6	1.6	-1.4	0.9	0.1	-0.3	-0.1	-0.2	1.8	0.3	-0.2
Depressed Affect (Nagel 2018)	0.1	0.2	1.0	0.5	0.6	0.3	-0.3	1.0	0.1	0.7	0.3	0.7	-0.5	0.1	-0.1	0.4	0.4	-0.3	0.5	0.1	-0.6
Neuroticism (Nagel 2018)	0.1	0.3	2.4	0.1	0.2	0.6	-0.4	1.5	0.1	0.8	-0.2	-0.0	0.4	-0.6	-0.8	0.0	-0.0	0.3	0.2	0.1	-0.1
Blood Red Count	0.1	0.8	4.2	-0.0	-0.4	0.3	0.5	-0.4	-2.0	0.1	-0.0	-1.8	1.7	-1.6	0.1	-0.3	-0.3	0.9	-0.6	0.4	0.2
Blood White Count	0.1	0.6	2.6	-0.7	-0.8	0.1	-1.4	1.1	0.2	0.6	-0.7	-0.6	0.3	-0.6	0.2	-0.9	-0.3	0.3	-0.7	0.6	1.6
Hair Pigment	0.1	2.9	8.5	-1.5	-1.5	-0.2	1.1	0.6	-0.9	-1.1	-1.1	-2.5	2.9	-2.7	-2.6	-1.7	-2.3	1.7	-1.5	0.2	0.5
Tanning	0.1	0.9	4.4	0.0	0.5	-0.2	-0.8	0.4	0.9	2.1	-0.6	0.8	-0.6	1.2	1.9	0.3	0.6	0.1	1.2	1.1	0.8
Neuroticism score	0.1	0.2	0.9	0.4	0.5	0.2	0.3	0.9	-0.3	0.3	0.3	0.2	0.1	-0.3	-0.5	0.3	0.2	-0.2	-0.5	-0.5	-0.6
Pulse rate	0.1	0.2	0.9	0.4	0.5	-0.4	-0.1	-0.1	0.9	0.2	0.4	0.8	0.2	0.7	-0.0	0.4	0.2	-0.7	0.3	0.2	0.1
Mood swings	0.1	0.2	1.0	-0.2	-0.2	-0.3	-0.3	-0.4	0.3	0.7	-0.2	1.0	-0.6	0.2	0.9	-0.3	-0.1	-0.6	-0.5	-0.4	-0.0
Age started oral contraceptive pill	0.1	0.2	0.5	-0.1	-0.2	-0.7	0.1	-0.7	-0.6	0.3	-0.3	-0.4	0.3	-0.3	-0.6	-0.2	-0.5	0.4	0.7	0.2	-0.3

Hub : Genes

MTERFD2

Models

Trait associations