[Hub]/) : Traits : Impedance of leg (right) :

chr5:176,040,488-177,591,495

Best TWAS P=2.42e-24 · Best GWAS P=1.24e-32 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex RAB24 0.14 0.06 enet 14 0.09 4.2e-11 6.6 7.4 1.6e-13 -0.31 1.00 0.00 FALSE
2 GTEx Adipose Visceral Omentum MXD3 0.33 0.06 lasso 6 0.05 9.1e-04 -5.5 -5.7 1.0e-08 0.32 0.29 0.04 FALSE
3 GTEx Brain Cerebellum MXD3 0.28 0.31 lasso 2 0.30 1.6e-09 -5.5 -5.4 7.2e-08 0.32 0.90 0.00 FALSE
4 GTEx Cells EBV-transformed lymphocytes RAB24 0.37 0.26 lasso 6 0.24 1.7e-08 -6.7 7.1 1.6e-12 -0.52 0.97 0.00 FALSE
5 GTEx Colon Sigmoid MXD3 0.35 0.27 lasso 9 0.29 6.3e-11 -5.5 -5.7 9.6e-09 0.39 0.98 0.00 FALSE
6 GTEx Colon Transverse PRELID1 0.31 0.28 lasso 4 0.26 1.1e-12 -5.4 5.4 5.8e-08 -0.34 1.00 0.00 FALSE
7 GTEx Esophagus Gastroesophageal Junction MXD3 0.17 0.12 lasso 3 0.08 9.5e-04 -5.4 -6.6 3.9e-11 0.34 0.08 0.06 TRUE
8 GTEx Esophagus Muscularis MXD3 0.27 0.20 enet 10 0.24 1.6e-14 -5.4 -5.2 2.3e-07 0.33 1.00 0.00 TRUE
9 GTEx Heart Left Ventricle MXD3 0.17 0.03 lasso 3 0.03 1.5e-02 -5.5 -5.3 1.3e-07 0.31 0.15 0.04 FALSE
10 GTEx Pituitary MXD3 0.25 0.20 lasso 6 0.16 7.5e-05 -4.8 -5.5 4.1e-08 0.46 0.37 0.06 FALSE
11 GTEx Skin Sun Exposed Lower leg PRELID1 0.06 0.02 enet 5 0.03 3.4e-03 -5.4 5.9 3.9e-09 -0.43 0.63 0.02 FALSE
12 GTEx Stomach MXD3 0.21 0.03 lasso 7 0.08 1.4e-04 -6.6 -6.1 9.5e-10 0.51 0.52 0.08 FALSE
13 GTEx Testis DBN1 0.10 0.00 lasso 6 0.00 4.6e-01 -4.7 5.8 7.5e-09 -0.45 0.06 0.04 FALSE
14 METSIM Adipose RAB24 0.05 0.02 lasso 4 0.02 1.2e-03 6.6 6.6 5.1e-11 -0.32 0.39 0.29 FALSE
15 ROSMAP Brain Pre-frontal Cortex PRELID1 0.05 0.05 enet 10 0.05 1.8e-07 -6.5 6.6 3.9e-11 -0.52 1.00 0.00 FALSE
16 YFS Blood PRELID1 0.18 0.14 enet 18 0.18 4.0e-58 -5.3 6.8 1.0e-11 -0.39 1.00 0.00 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma MXD3 0.02 0.02 enet 4 0.02 1.8e-04 -6.5 -6.6 5.5e-11 0.52 0.22 0.74 FALSE
18 The Cancer Genome Atlas Colon Adenocarcinoma PRELID1 0.09 0.01 blup 38 0.05 1.1e-03 -5.4 5.3 1.2e-07 -0.16 0.05 0.36 TRUE
19 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FGFR4 0.08 0.06 blup 46 0.07 2.5e-08 -11.9 6.3 3.9e-10 -0.75 0.00 1.00 TRUE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MXD3 0.05 0.00 lasso 6 0.00 6.9e-01 -7.2 -6.5 7.8e-11 0.22 0.02 0.15 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PRELID1 0.24 0.11 lasso 5 0.10 1.2e-11 -5.4 5.5 4.2e-08 -0.32 1.00 0.00 FALSE
22 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma PRELID1 0.33 0.08 enet 4 0.08 2.7e-05 -5.4 5.5 3.5e-08 -0.33 0.50 0.05 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma MXD3 0.04 0.02 lasso 3 0.02 2.9e-03 -6.1 -6.7 1.6e-11 0.53 0.02 0.58 FALSE
24 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PRELID1 0.08 0.10 lasso 4 0.07 2.9e-04 -5.3 5.5 3.5e-08 -0.27 0.11 0.48 FALSE
25 The Cancer Genome Atlas Lung Adenocarcinoma MXD3 0.04 0.02 blup 41 0.02 5.6e-04 -6.1 -7.3 2.1e-13 0.52 0.02 0.90 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma FGFR4 0.11 0.04 enet 19 0.06 8.7e-07 -11.9 10.2 2.4e-24 -0.87 0.00 1.00 TRUE
27 The Cancer Genome Atlas Prostate Adenocarcinoma MXD3 0.04 0.02 blup 40 0.03 2.8e-04 -5.4 -7.1 1.6e-12 0.48 0.02 0.96 TRUE
28 The Cancer Genome Atlas Thyroid Carcinoma MXD3 0.05 0.04 lasso 5 0.04 1.8e-04 -6.6 -6.5 9.5e-11 0.53 0.20 0.68 FALSE