Best TWAS P=2.59e-11 · Best GWAS P=1.67e-10 conditioned to 0.000581
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | RNF130 | 0.16 | 0.00 | enet | 21 | 0.01 | 1.5e-01 | -6.1 | 5.5 | 4.2e-08 | -0.64 | 0.03 | 0.71 | FALSE |
| 2 | GTEx | Esophagus Mucosa | RNF130 | 0.11 | 0.00 | lasso | 8 | 0.00 | 7.3e-01 | -2.2 | 6.7 | 2.6e-11 | -0.52 | 0.04 | 0.82 | TRUE |
| 3 | GTEx | Muscle Skeletal | RNF130 | 0.12 | 0.03 | lasso | 5 | 0.07 | 3.3e-07 | -2.1 | 5.1 | 3.0e-07 | -0.45 | 0.48 | 0.51 | FALSE |
| 4 | METSIM | Adipose | LTC4S | 0.05 | 0.04 | lasso | 4 | 0.02 | 1.5e-04 | -6.1 | -6.1 | 9.2e-10 | 0.91 | 0.02 | 0.98 | FALSE |