TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of leg (left)
:
←
→
chr8:66,679,221-68,096,452
Best TWAS P=2.42e-08 · Best GWAS P=1.26e-06 conditioned to 0.0675
66.6M
66.8M
67M
67.2M
67.4M
67.6M
67.8M
68M
0
1
2
3
4
5
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Muscularis
C8orf46
0.39
0.22
enet
30
0.18
8.5e-11
-4
-5.6
2.4e-08
-0.61
0.13
0.63
TRUE