[Hub]/) : Traits : Impedance of leg (left) : ← →

chr11:15,288,270-18,106,069

Best TWAS P=1.63e-12 · Best GWAS P=3.92e-11 conditioned to 0.141

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	KCNJ11	0.04	0.03	lasso	3	0.03	2.6e-04	6.0	6.1	1.4e-09	0.94	0.01	0.98	FALSE
2	GTEx	Adipose Subcutaneous	RP1-239B22.5	0.11	0.06	enet	21	0.07	1.5e-06	6.4	-5.7	1.5e-08	-0.80	0.00	1.00	FALSE
3	GTEx	Adrenal Gland	SOX6	0.32	0.17	lasso	5	0.16	1.6e-06	4.9	-5.2	1.6e-07	-0.01	0.05	0.94	TRUE
4	GTEx	Esophagus Mucosa	KCNJ11	0.27	0.16	lasso	8	0.22	1.6e-14	-4.0	-5.7	9.4e-09	-0.77	0.27	0.73	FALSE
5	GTEx	Esophagus Mucosa	NCR3LG1	0.38	0.38	enet	39	0.42	3.7e-30	-4.0	-5.2	1.6e-07	-0.71	1.00	0.00	FALSE
6	GTEx	Esophagus Mucosa	RP1-239B22.5	0.28	0.28	enet	47	0.32	2.9e-22	-4.0	-5.3	1.2e-07	-0.73	0.96	0.04	FALSE
7	GTEx	Nerve Tibial	RP1-239B22.5	0.11	0.08	lasso	2	0.08	2.9e-06	-3.4	-5.5	3.7e-08	-0.74	0.02	0.96	FALSE
8	GTEx	Skin Not Sun Exposed Suprapubic	KCNJ11	0.18	0.07	lasso	6	0.12	7.0e-07	6.0	-6.4	1.2e-10	-0.86	0.01	0.99	FALSE
9	GTEx	Skin Sun Exposed Lower leg	KCNJ11	0.23	0.09	lasso	10	0.12	1.7e-10	6.6	-6.7	1.9e-11	-0.89	0.01	0.99	FALSE
10	GTEx	Skin Sun Exposed Lower leg	NCR3LG1	0.12	0.12	lasso	5	0.13	5.0e-11	-4.2	-5.2	2.2e-07	-0.51	0.98	0.02	FALSE
11	GTEx	Skin Sun Exposed Lower leg	RP1-239B22.5	0.06	0.06	lasso	2	0.07	8.6e-07	-4.2	-5.8	6.3e-09	-0.81	0.02	0.98	FALSE
12	ROSMAP	Brain Pre-frontal Cortex	KCNJ11	0.05	0.06	enet	6	0.05	3.0e-07	4.8	5.4	8.5e-08	0.74	0.18	0.81	FALSE
13	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DKFZp686O24166	0.05	0.03	blup	71	0.04	1.2e-05	-5.3	-7.1	1.6e-12	-0.80	0.02	0.98	TRUE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DKFZp686O24166	0.03	0.01	blup	72	0.03	2.4e-04	6.5	-5.9	4.2e-09	-0.83	0.01	0.96	FALSE
15	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	DKFZp686O24166	0.08	0.07	lasso	4	0.05	1.2e-03	-4.1	-5.3	1.4e-07	-0.71	0.04	0.92	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	DKFZp686O24166	0.04	0.01	blup	71	0.02	1.5e-03	6.0	-5.2	2.0e-07	-0.81	0.01	0.88	FALSE