TWAS
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Traits
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Traits
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Impedance of leg (left)
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chr11:29,713,564-31,288,160
Best TWAS P=6.9e-08 · Best GWAS P=6.25e-10 conditioned to 1
29.8M
30M
30.2M
30.4M
30.6M
30.8M
31M
31.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
ROSMAP
Brain Pre-frontal Cortex
MPPED2
0.25
0.29
lasso
7
0.29
4.4e-37
-5.4
5.4
6.9e-08
-0.97
0.01
0.99
TRUE