[Hub]/) : Traits : Impedance of leg (left) : ← →

chr1:177,195,050-178,753,162

Best TWAS P=1.68e-16 · Best GWAS P=7.76e-47 conditioned to 4.71e-28

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	GTEx	Skin Sun Exposed Lower leg	RP11-568K15.1	0.11	0.05	enet	20	0.04	1.3e-04	-6.2	8.2	1.7e-16	-0.38	0.57	0.11	TRUE
12	GTEx	Lung	RASAL2-AS1	0.14	0.01	lasso	7	0.05	1.1e-04	1.2	-5.3	9.5e-08	0.49	0.53	0.09	TRUE
1	CommonMind	Brain Pre-frontal Cortex	LOC730102	0.18	0.12	lasso	9	0.12	1.4e-14	-6.2	7.1	1.2e-12	-0.31	1.00	0.00	FALSE
11	GTEx	Heart Atrial Appendage	RP11-568K15.1	0.22	0.17	lasso	6	0.18	2.7e-08	-6.2	6.7	2.4e-11	-0.29	0.92	0.01	FALSE
14	GTEx	Muscle Skeletal	SEC16B	0.18	0.04	lasso	6	0.05	2.3e-05	-6.2	-6.3	2.1e-10	0.32	0.47	0.02	FALSE
5	GTEx	Artery Tibial	RP11-568K15.1	0.14	0.10	lasso	4	0.10	2.0e-08	-6.2	6.3	2.8e-10	-0.28	0.98	0.00	FALSE
15	GTEx	Muscle Skeletal	RP4-798P15.3	0.18	0.02	lasso	6	0.04	1.7e-04	-6.2	-6.3	3.1e-10	0.32	0.28	0.03	FALSE
7	GTEx	Breast Mammary Tissue (Male)	RP11-568K15.1	0.15	0.18	lasso	3	0.15	2.1e-04	-6.2	6.2	4.6e-10	-0.28	0.06	0.08	FALSE
13	GTEx	Lung	RP11-568K15.1	0.22	0.06	lasso	5	0.14	6.4e-11	-6.2	6.0	1.4e-09	-0.27	0.99	0.00	FALSE
2	GTEx	Adipose Subcutaneous	RP11-568K15.1	0.38	0.21	lasso	9	0.20	1.3e-16	-6.2	6.0	1.5e-09	-0.27	1.00	0.00	FALSE
6	GTEx	Breast Mammary Tissue	RP11-568K15.1	0.20	0.11	lasso	7	0.09	2.0e-05	-6.2	5.8	8.8e-09	-0.27	0.75	0.01	FALSE
9	GTEx	Esophagus Mucosa	RP11-568K15.1	0.22	0.11	lasso	7	0.13	5.9e-09	-6.2	5.7	1.2e-08	-0.27	0.89	0.06	FALSE
10	GTEx	Esophagus Muscularis	RP11-568K15.1	0.26	0.17	lasso	7	0.18	5.7e-11	-6.2	5.5	3.4e-08	-0.25	1.00	0.00	FALSE
4	GTEx	Artery Aorta	RP11-568K15.1	0.28	0.02	lasso	10	0.14	3.2e-08	-6.2	5.4	6.8e-08	-0.25	0.80	0.02	FALSE
16	GTEx	Nerve Tibial	RP11-568K15.1	0.44	0.15	enet	37	0.27	3.4e-19	-6.2	5.4	7.3e-08	-0.27	1.00	0.00	FALSE
8	GTEx	Cells Transformed fibroblasts	RP11-568K15.1	0.39	0.15	lasso	10	0.22	2.5e-16	-4.7	5.2	1.8e-07	-0.26	1.00	0.00	FALSE
3	GTEx	Adipose Visceral Omentum	RP11-568K15.1	0.29	0.04	lasso	4	0.14	9.4e-08	1.9	5.2	2.5e-07	-0.24	0.72	0.02	FALSE