Best TWAS P=1.08e-10 · Best GWAS P=4.8e-11 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | GNAO1 | 0.13 | 0.12 | lasso | 4 | 0.11 | 6.0e-09 | -6.0 | 6.3 | 3.1e-10 | -0.88 | 0.05 | 0.95 | FALSE |
| 2 | GTEx | Esophagus Muscularis | GNAO1 | 0.09 | 0.03 | lasso | 3 | 0.06 | 1.1e-04 | 4.6 | 5.2 | 1.5e-07 | -0.44 | 0.20 | 0.59 | FALSE |
| 3 | GTEx | Muscle Skeletal | GNAO1 | 0.06 | 0.00 | lasso | 3 | 0.00 | 1.1e-01 | -6.4 | -6.5 | 1.1e-10 | 0.96 | 0.02 | 0.81 | TRUE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GNAO1 | 0.06 | 0.00 | blup | 103 | 0.01 | 2.0e-02 | 4.4 | 6.0 | 1.7e-09 | -0.68 | 0.05 | 0.63 | FALSE |