[Hub]/) : Traits : Impedance of leg (left) :

chr2:26,223,547-28,414,302

Best TWAS P=5.42e-23 · Best GWAS P=1.19e-20 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Breast Mammary Tissue (Female) AC074117.10 0.06 0.01 lasso 2 0.04 2.7e-02 -6.7 -7.4 1.1e-13 -0.23 0.04 0.05 TRUE
2 GTEx Stomach AC074117.10 0.06 0.01 lasso 7 0.01 7.8e-02 -2.5 -9.1 9.1e-20 -0.36 0.19 0.08 FALSE
3 GTEx Thyroid FNDC4 0.24 0.10 enet 23 0.16 2.2e-12 -7.9 -9.2 5.7e-20 -0.69 0.67 0.33 FALSE
4 ROSMAP Brain Pre-frontal Cortex KCNK3 0.24 0.15 lasso 3 0.15 6.5e-19 -5.5 5.8 7.5e-09 0.09 0.01 0.99 TRUE
5 The Cancer Genome Atlas Breast Invasive Carcinoma GPN1 0.06 0.02 lasso 6 0.02 7.2e-05 7.6 6.0 1.7e-09 0.54 0.23 0.03 FALSE
6 The Cancer Genome Atlas Breast Invasive Carcinoma SNX17 0.08 0.01 blup 25 0.02 6.6e-05 -4.0 -5.1 3.1e-07 -0.55 0.02 0.34 FALSE
7 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma SUPT7L 0.06 0.03 blup 29 0.05 2.0e-03 -8.3 -6.7 1.6e-11 -0.04 0.01 0.84 TRUE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SUPT7L 0.05 0.02 blup 28 0.04 5.2e-05 -8.4 -9.7 3.7e-22 -0.40 0.00 0.98 TRUE
9 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FNDC4 0.13 0.06 lasso 2 0.05 1.1e-03 9.3 -9.9 5.4e-23 -0.99 0.00 0.96 TRUE
10 The Cancer Genome Atlas Thyroid Carcinoma FNDC4 0.24 0.09 enet 9 0.17 1.9e-16 -8.0 -9.1 1.1e-19 -0.70 0.41 0.59 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma GCKR 0.18 0.08 enet 5 0.13 1.7e-12 -7.9 -8.5 2.1e-17 -0.64 0.90 0.10 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma IFT172 0.08 0.01 blup 43 0.02 6.1e-03 -7.6 -8.5 2.8e-17 -0.54 0.02 0.27 FALSE