[Hub]/) : Traits : Impedance of leg (left) : ← →

chr2:241,239,377-242,991,746

Best TWAS P=1.16e-11 · Best GWAS P=3.4e-12 conditioned to 0.947

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	GTEx	Whole Blood	PASK	0.25	0.15	enet	10	0.21	4.4e-19	6.1	-6.8	1.2e-11	-0.57	0.27	0.73	TRUE
5	GTEx	Muscle Skeletal	PASK	0.06	0.00	enet	13	0.01	8.6e-02	5.1	-6.4	2.0e-10	-0.58	0.03	0.64	TRUE
8	GTEx	Skin Not Sun Exposed Suprapubic	AC005104.3	0.27	0.06	enet	24	0.20	5.6e-11	-2.1	-5.6	1.8e-08	-0.24	0.60	0.04	TRUE
3	GTEx	Heart Left Ventricle	PASK	0.10	0.03	lasso	6	0.03	9.4e-03	-5.3	-6.8	1.3e-11	-0.62	0.03	0.79	FALSE
18	YFS	Blood	PASK	0.31	0.46	lasso	11	0.48	1.8e-181	6.1	-6.6	3.7e-11	-0.62	0.40	0.60	FALSE
16	NTR	Blood	PASK	0.08	0.09	bslmm	437	0.09	1.0e-26	6.2	-6.4	1.2e-10	-0.60	0.22	0.78	FALSE
10	GTEx	Small Intestine Terminal Ileum	MTERFD2	0.37	0.24	lasso	3	0.18	7.3e-05	6.2	-6.4	1.3e-10	-0.57	0.12	0.38	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	SNED1	0.17	0.12	lasso	4	0.14	5.2e-18	4.6	6.3	2.9e-10	0.54	0.96	0.04	FALSE
6	GTEx	Nerve Tibial	PASK	0.26	0.18	enet	12	0.22	1.0e-15	5.1	-6.2	7.2e-10	-0.59	0.98	0.02	FALSE
11	GTEx	Testis	MTERFD2	0.43	0.17	enet	32	0.25	1.4e-11	6.2	6.2	7.4e-10	0.58	0.20	0.80	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	PASK	0.28	0.16	enet	17	0.19	1.9e-10	4.9	-6.1	8.2e-10	-0.69	0.93	0.07	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PASK	0.04	0.00	blup	92	0.01	3.2e-02	6.2	-6.0	1.9e-09	-0.50	0.04	0.16	FALSE
4	GTEx	Lung	PASK	0.09	0.02	lasso	2	0.03	3.7e-03	-4.3	-6.0	2.0e-09	-0.47	0.43	0.05	FALSE
15	METSIM	Adipose	PASK	0.09	0.03	bslmm	441	0.08	9.4e-12	7.0	-5.8	5.7e-09	-0.71	0.00	1.00	FALSE
1	GTEx	Adipose Subcutaneous	PASK	0.17	0.09	enet	13	0.09	8.3e-08	5.1	-5.7	1.4e-08	-0.66	0.93	0.07	FALSE
2	GTEx	Esophagus Mucosa	PASK	0.19	0.13	lasso	6	0.14	1.1e-09	5.1	-5.4	6.3e-08	-0.59	0.99	0.01	FALSE
12	GTEx	Thyroid	PASK	0.22	0.04	enet	41	0.09	1.2e-07	5.4	-5.3	1.4e-07	-0.49	0.60	0.32	FALSE
9	GTEx	Skin Sun Exposed Lower leg	PASK	0.27	0.18	enet	10	0.18	4.5e-15	4.9	-5.3	1.5e-07	-0.58	1.00	0.00	FALSE
13	GTEx	Thyroid	MTERFD2	0.12	0.09	lasso	2	0.08	1.8e-06	6.1	-5.2	2.2e-07	-0.47	0.28	0.71	FALSE