[Hub]/) : Traits : Impedance of leg (left) :

chr2:241,239,377-242,991,746

Best TWAS P=1.16e-11 · Best GWAS P=3.4e-12 conditioned to 0.947

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PASK 0.17 0.09 enet 13 0.09 8.3e-08 5.1 -5.7 1.4e-08 -0.66 0.93 0.07 FALSE
2 GTEx Esophagus Mucosa PASK 0.19 0.13 lasso 6 0.14 1.1e-09 5.1 -5.4 6.3e-08 -0.59 0.99 0.01 FALSE
3 GTEx Heart Left Ventricle PASK 0.10 0.03 lasso 6 0.03 9.4e-03 -5.3 -6.8 1.3e-11 -0.62 0.03 0.79 FALSE
4 GTEx Lung PASK 0.09 0.02 lasso 2 0.03 3.7e-03 -4.3 -6.0 2.0e-09 -0.47 0.43 0.05 FALSE
5 GTEx Muscle Skeletal PASK 0.06 0.00 enet 13 0.01 8.6e-02 5.1 -6.4 2.0e-10 -0.58 0.03 0.64 TRUE
6 GTEx Nerve Tibial PASK 0.26 0.18 enet 12 0.22 1.0e-15 5.1 -6.2 7.2e-10 -0.59 0.98 0.02 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic PASK 0.28 0.16 enet 17 0.19 1.9e-10 4.9 -6.1 8.2e-10 -0.69 0.93 0.07 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic AC005104.3 0.27 0.06 enet 24 0.20 5.6e-11 -2.1 -5.6 1.8e-08 -0.24 0.60 0.04 TRUE
9 GTEx Skin Sun Exposed Lower leg PASK 0.27 0.18 enet 10 0.18 4.5e-15 4.9 -5.3 1.5e-07 -0.58 1.00 0.00 FALSE
10 GTEx Small Intestine Terminal Ileum MTERFD2 0.37 0.24 lasso 3 0.18 7.3e-05 6.2 -6.4 1.3e-10 -0.57 0.12 0.38 FALSE
11 GTEx Testis MTERFD2 0.43 0.17 enet 32 0.25 1.4e-11 6.2 6.2 7.4e-10 0.58 0.20 0.80 FALSE
12 GTEx Thyroid PASK 0.22 0.04 enet 41 0.09 1.2e-07 5.4 -5.3 1.4e-07 -0.49 0.60 0.32 FALSE
13 GTEx Thyroid MTERFD2 0.12 0.09 lasso 2 0.08 1.8e-06 6.1 -5.2 2.2e-07 -0.47 0.28 0.71 FALSE
14 GTEx Whole Blood PASK 0.25 0.15 enet 10 0.21 4.4e-19 6.1 -6.8 1.2e-11 -0.57 0.27 0.73 TRUE
15 METSIM Adipose PASK 0.09 0.03 bslmm 441 0.08 9.4e-12 7.0 -5.8 5.7e-09 -0.71 0.00 1.00 FALSE
16 NTR Blood PASK 0.08 0.09 bslmm 437 0.09 1.0e-26 6.2 -6.4 1.2e-10 -0.60 0.22 0.78 FALSE
17 ROSMAP Brain Pre-frontal Cortex SNED1 0.17 0.12 lasso 4 0.14 5.2e-18 4.6 6.3 2.9e-10 0.54 0.96 0.04 FALSE
18 YFS Blood PASK 0.31 0.46 lasso 11 0.48 1.8e-181 6.1 -6.6 3.7e-11 -0.62 0.40 0.60 FALSE
19 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PASK 0.04 0.00 blup 92 0.01 3.2e-02 6.2 -6.0 1.9e-09 -0.50 0.04 0.16 FALSE