[Hub]/) : Traits : Impedance of leg (left) : ← →

chr3:13,327,947-14,916,048

Best TWAS P=5.18e-10 · Best GWAS P=5.27e-16 conditioned to 1.87e-09

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Heart Left Ventricle	CHCHD4	0.14	0.11	enet	16	0.11	1.5e-06	5.3	6.2	5.2e-10	0.03	0.03	0.96	TRUE
8	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	FBLN2	0.05	0.01	enet	12	0.02	7.3e-04	8.0	5.6	2.0e-08	0.85	0.01	0.97	TRUE
9	The Cancer Genome Atlas	Thyroid Carcinoma	CHCHD4	0.04	0.00	blup	43	0.01	1.6e-02	-2.9	5.6	1.8e-08	0.01	0.02	0.59	FALSE
2	GTEx	Esophagus Muscularis	CHCHD4	0.10	0.08	lasso	3	0.07	4.1e-05	5.3	5.6	2.4e-08	0.02	0.06	0.92	FALSE
6	ROSMAP	Brain Pre-frontal Cortex	CHCHD4	0.12	0.11	lasso	8	0.10	2.2e-12	5.3	5.4	6.9e-08	-0.02	0.08	0.92	FALSE
4	GTEx	Muscle Skeletal	CHCHD4	0.10	0.11	lasso	2	0.10	6.6e-10	5.3	5.3	1.2e-07	-0.01	0.10	0.90	FALSE
5	NTR	Blood	XPC	0.03	0.02	bslmm	575	0.01	3.0e-05	-4.2	-5.2	1.5e-07	0.00	0.19	0.80	FALSE
7	YFS	Blood	XPC	0.04	0.01	lasso	5	0.02	3.2e-07	-5.6	5.2	1.5e-07	-0.03	0.03	0.97	FALSE
1	GTEx	Cells Transformed fibroblasts	XPC	0.11	0.04	lasso	6	0.04	3.2e-04	5.3	-5.1	3.0e-07	0.00	0.02	0.94	FALSE