[Hub]/) : Traits : Impedance of leg (left) : ← →

chr3:37,692,342-39,280,382

Best TWAS P=8.2e-11 · Best GWAS P=1.27e-10 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	EXOG	0.02	0.02	blup	56	0.01	1.0e-02	6.4	6.5	8.2e-11	0.97	0.02	0.90	TRUE
12	GTEx	Testis	EXOG	0.35	0.28	lasso	5	0.26	8.1e-12	6.4	6.5	1.1e-10	0.92	0.03	0.97	FALSE
24	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	XYLB	0.05	0.03	lasso	4	0.02	2.4e-03	6.3	-6.4	1.9e-10	-0.98	0.01	0.98	FALSE
5	GTEx	Brain Frontal Cortex BA9	EXOG	0.18	0.08	lasso	4	0.05	1.7e-02	6.4	6.3	2.1e-10	0.90	0.04	0.84	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	ACVR2B	0.02	0.00	blup	49	0.01	1.6e-02	6.2	-6.2	6.0e-10	-0.97	0.02	0.60	FALSE
11	GTEx	Stomach	EXOG	0.14	0.05	lasso	6	0.02	2.5e-02	6.0	6.2	7.0e-10	0.91	0.04	0.92	FALSE
8	GTEx	Esophagus Mucosa	EXOG	0.13	0.05	lasso	3	0.03	5.0e-03	6.0	6.1	1.0e-09	0.90	0.07	0.83	FALSE
13	GTEx	Thyroid	EXOG	0.19	0.20	lasso	3	0.19	2.9e-14	6.1	6.0	1.6e-09	0.92	0.04	0.96	FALSE
15	NTR	Blood	EXOG	0.02	0.03	lasso	6	0.03	1.0e-09	5.7	-6.0	2.4e-09	-0.98	0.05	0.95	FALSE
3	GTEx	Brain Cerebellum	EXOG	0.19	0.23	enet	4	0.21	7.7e-07	6.0	5.9	2.9e-09	0.91	0.09	0.87	FALSE
6	GTEx	Breast Mammary Tissue	EXOG	0.08	0.06	enet	10	0.05	8.6e-04	4.1	5.9	3.9e-09	0.82	0.05	0.90	FALSE
14	NTR	Blood	ACVR2B	0.02	0.02	lasso	3	0.02	5.6e-07	5.2	5.9	4.3e-09	0.87	0.05	0.95	FALSE
25	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	EXOG	0.10	0.02	blup	56	0.03	2.1e-02	2.2	5.8	4.8e-09	0.76	0.02	0.49	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ACVR2B	0.08	0.08	enet	15	0.09	9.6e-11	5.7	-5.8	5.2e-09	-0.97	0.03	0.97	FALSE
4	GTEx	Brain Cerebellum	ACVR2B-AS1	0.25	0.07	lasso	6	0.10	8.3e-04	6.1	5.8	5.7e-09	0.84	0.04	0.91	FALSE
29	The Cancer Genome Atlas	Thyroid Carcinoma	LOC100128640	0.07	0.03	blup	28	0.03	1.0e-03	6.4	-5.8	6.9e-09	-0.93	0.02	0.96	FALSE
7	GTEx	Colon Transverse	XYLB	0.08	0.03	enet	15	0.05	1.7e-03	6.4	-5.8	7.2e-09	-0.82	0.03	0.93	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	XYLB	0.05	0.06	enet	7	0.05	3.5e-06	6.3	-5.7	1.3e-08	-0.92	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	EXOG	0.10	0.00	enet	12	0.00	1.3e-01	6.0	5.7	1.4e-08	0.60	0.04	0.55	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	EXOG	0.10	0.13	lasso	2	0.12	4.8e-15	6.0	5.7	1.4e-08	0.91	0.08	0.92	FALSE
21	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	EXOG	0.14	0.09	blup	56	0.09	9.5e-06	6.1	5.7	1.5e-08	0.76	0.02	0.97	FALSE
19	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	EXOG	0.04	0.01	blup	56	0.03	2.2e-04	5.2	5.6	2.1e-08	0.68	0.03	0.74	FALSE
10	GTEx	Pancreas	EXOG	0.22	0.08	enet	15	0.03	2.6e-02	6.4	5.5	3.7e-08	0.89	0.03	0.94	FALSE
9	GTEx	Ovary	EXOG	0.33	0.25	lasso	8	0.21	8.1e-06	5.2	5.4	6.9e-08	0.82	0.09	0.72	FALSE
18	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	XYLB	0.06	0.05	blup	82	0.04	5.2e-03	6.3	-5.4	7.8e-08	-0.95	0.01	0.88	FALSE
20	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	XYLB	0.03	0.03	blup	82	0.02	5.1e-03	6.3	-5.4	8.5e-08	-0.92	0.02	0.95	FALSE
16	NTR	Blood	XYLB	0.05	0.06	lasso	3	0.06	6.2e-18	5.2	5.3	1.1e-07	0.79	0.83	0.17	FALSE
22	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	LOC100128640	0.09	0.05	lasso	2	0.03	1.7e-02	5.2	-5.2	1.7e-07	-0.78	0.02	0.50	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	LOC100128640	0.08	0.02	blup	28	0.03	2.6e-04	6.4	-5.2	1.7e-07	-0.62	0.02	0.94	FALSE