Best TWAS P=2.92e-11 · Best GWAS P=1.05e-11 conditioned to 9.32e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | WDR70 | 0.06 | 0.03 | lasso | 8 | 0.03 | 0.00346 | 6.1 | -6.7 | 2.9e-11 | 0.52 | 0.18 | 0.73 | TRUE |
| 2 | GTEx | Nerve Tibial | WDR70 | 0.17 | 0.07 | lasso | 3 | 0.05 | 0.00014 | -6.1 | -6.0 | 2.2e-09 | 0.92 | 0.16 | 0.61 | FALSE |
| 3 | GTEx | Whole Blood | NUP155 | 0.05 | 0.01 | enet | 14 | 0.04 | 0.00011 | 6.6 | -5.4 | 7.3e-08 | 0.40 | 0.04 | 0.60 | FALSE |
| 4 | GTEx | Whole Blood | C5orf42 | 0.07 | 0.00 | enet | 16 | 0.01 | 0.01830 | 6.6 | -6.1 | 1.1e-09 | 0.49 | 0.04 | 0.59 | FALSE |
| 5 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | C5orf42 | 0.04 | 0.05 | lasso | 3 | 0.04 | 0.00108 | 6.6 | -6.4 | 1.2e-10 | 0.45 | 0.01 | 0.73 | FALSE |