[Hub]/) : Traits : Impedance of leg (left) : ← →

chr5:42,076,094-44,403,631

Best TWAS P=1.08e-10 · Best GWAS P=3.39e-08 conditioned to 0.148

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	NNT	0.15	0.03	enet	21	0.07	3.3e-06	-3.4	-5.8	9.0e-09	0.39	0.38	0.54	FALSE
2	GTEx	Adipose Subcutaneous	CCDC152	0.09	0.04	lasso	4	0.02	6.4e-03	-5.1	-5.1	3.1e-07	0.11	0.03	0.97	TRUE
3	GTEx	Adrenal Gland	NNT	0.17	0.15	lasso	4	0.07	1.3e-03	4.9	-5.7	1.2e-08	0.56	0.06	0.91	FALSE
4	GTEx	Brain Caudate basal ganglia	C5orf34	0.14	-0.01	enet	14	0.00	3.3e-01	-5.0	-6.5	1.1e-10	0.59	0.05	0.63	TRUE
5	GTEx	Cells Transformed fibroblasts	NNT-AS1	0.08	0.04	lasso	5	0.05	7.8e-05	-4.9	5.1	2.8e-07	-0.52	0.07	0.91	FALSE
6	GTEx	Esophagus Mucosa	NNT	0.31	0.24	lasso	8	0.26	1.4e-17	-4.7	-6.0	1.9e-09	0.54	0.16	0.83	FALSE
7	GTEx	Skin Sun Exposed Lower leg	NNT	0.05	0.04	enet	11	0.04	4.3e-04	-4.9	-5.8	6.1e-09	0.65	0.05	0.91	FALSE
8	GTEx	Small Intestine Terminal Ileum	NNT	0.19	0.05	enet	31	0.10	3.8e-03	-4.9	-5.6	2.5e-08	0.53	0.06	0.64	FALSE
9	GTEx	Thyroid	C5orf34	0.08	0.08	lasso	3	0.06	1.4e-05	-4.6	-5.5	4.3e-08	0.63	0.11	0.84	FALSE
10	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	C5orf34	0.04	0.01	enet	4	0.03	1.5e-03	-4.9	-5.9	3.3e-09	0.49	0.01	0.76	FALSE
11	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	C5orf34	0.11	0.12	enet	13	0.11	2.9e-12	-4.9	-5.7	1.3e-08	0.54	0.01	0.98	FALSE
12	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	NNT	0.04	0.01	enet	9	0.02	3.4e-03	-3.9	-5.6	2.7e-08	0.52	0.01	0.72	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C5orf34	0.05	0.06	blup	39	0.05	3.2e-06	-4.9	-6.1	1.4e-09	0.58	0.01	0.98	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	NNT	0.07	0.01	blup	49	0.05	2.1e-06	-4.7	-5.3	9.6e-08	0.39	0.01	0.96	FALSE
15	The Cancer Genome Atlas	Lung Adenocarcinoma	C5orf34	0.04	0.03	blup	39	0.03	1.5e-04	-4.9	-5.3	1.2e-07	0.54	0.01	0.98	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	NNT	0.06	0.01	enet	7	0.02	9.0e-04	-4.9	-5.5	4.2e-08	0.45	0.01	0.90	FALSE
17	The Cancer Genome Atlas	Prostate Adenocarcinoma	HMGCS1	0.04	0.03	blup	37	0.03	1.5e-04	-4.8	5.4	5.5e-08	-0.88	0.02	0.96	FALSE
18	The Cancer Genome Atlas	Stomach Adenocarcinoma	C5orf34	0.09	0.02	enet	9	0.04	3.7e-04	-4.9	-5.7	1.2e-08	0.58	0.01	0.84	FALSE
19	The Cancer Genome Atlas	Stomach Adenocarcinoma	NNT	0.04	0.01	blup	48	0.02	1.2e-02	4.9	-5.6	1.7e-08	0.51	0.01	0.73	FALSE
20	The Cancer Genome Atlas	Thyroid Carcinoma	MGC42105	0.04	0.01	blup	63	0.01	4.3e-02	1.9	5.7	1.2e-08	-0.48	0.01	0.15	FALSE