TWAS
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Traits
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Traits
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Impedance of leg (left)
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chr5:77,052,232-77,837,260
Best TWAS P=1.77e-08 · Best GWAS P=1.96e-07 conditioned to 0.486
77.1M
77.2M
77.3M
77.4M
77.5M
77.6M
77.7M
77.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
AP3B1
0.02
0.00
blup
126
0.01
0.0182
5.2
5.6
1.8e-08
0.86
0.02
0.86
TRUE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
AP3B1
0.05
0.02
blup
126
0.03
0.0005
-5.0
5.5
4.0e-08
0.80
0.02
0.91
FALSE