Best TWAS P=7.64e-19 · Best GWAS P=4.41e-24 conditioned to 7.83e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KRT8P33 | 0.10 | 0.04 | lasso | 6 | 0.05 | 9.1e-04 | 5.8 | -7.5 | 8.4e-14 | -0.62 | 0.03 | 0.87 | FALSE |
| 2 | GTEx | Esophagus Mucosa | CSNK1G3 | 0.14 | 0.05 | lasso | 3 | 0.07 | 2.0e-05 | -6.0 | -5.8 | 5.1e-09 | -0.44 | 0.78 | 0.11 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CSNK1G3 | 0.04 | 0.02 | enet | 8 | 0.02 | 1.2e-04 | -6.0 | -6.7 | 2.4e-11 | -0.56 | 0.01 | 0.62 | FALSE |
| 4 | The Cancer Genome Atlas | Colon Adenocarcinoma | CEP120 | 0.06 | 0.02 | blup | 70 | 0.04 | 3.6e-03 | -3.8 | -6.4 | 1.2e-10 | -0.64 | 0.12 | 0.17 | FALSE |
| 5 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CEP120 | 0.03 | 0.02 | enet | 5 | 0.04 | 7.3e-05 | 5.8 | -6.8 | 1.1e-11 | -0.66 | 0.03 | 0.83 | FALSE |
| 6 | The Cancer Genome Atlas | Lung Adenocarcinoma | CSNK1G3 | 0.06 | 0.05 | lasso | 2 | 0.04 | 2.0e-05 | -6.0 | -5.9 | 3.1e-09 | -0.44 | 0.02 | 0.97 | FALSE |
| 7 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP120 | 0.10 | 0.14 | blup | 70 | 0.14 | 2.6e-14 | 9.4 | -8.9 | 7.6e-19 | -0.83 | 0.15 | 0.85 | TRUE |
| 8 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CSNK1G3 | 0.06 | 0.04 | enet | 10 | 0.05 | 2.3e-06 | -6.2 | -7.5 | 8.6e-14 | -0.57 | 0.01 | 0.99 | FALSE |