[Hub]/) : Traits : Impedance of leg (left) :

chr5:122,045,488-123,649,166

Best TWAS P=7.64e-19 · Best GWAS P=4.41e-24 conditioned to 7.83e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta KRT8P33 0.10 0.04 lasso 6 0.05 9.1e-04 5.8 -7.5 8.4e-14 -0.62 0.03 0.87 FALSE
2 GTEx Esophagus Mucosa CSNK1G3 0.14 0.05 lasso 3 0.07 2.0e-05 -6.0 -5.8 5.1e-09 -0.44 0.78 0.11 FALSE
3 The Cancer Genome Atlas Breast Invasive Carcinoma CSNK1G3 0.04 0.02 enet 8 0.02 1.2e-04 -6.0 -6.7 2.4e-11 -0.56 0.01 0.62 FALSE
4 The Cancer Genome Atlas Colon Adenocarcinoma CEP120 0.06 0.02 blup 70 0.04 3.6e-03 -3.8 -6.4 1.2e-10 -0.64 0.12 0.17 FALSE
5 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CEP120 0.03 0.02 enet 5 0.04 7.3e-05 5.8 -6.8 1.1e-11 -0.66 0.03 0.83 FALSE
6 The Cancer Genome Atlas Lung Adenocarcinoma CSNK1G3 0.06 0.05 lasso 2 0.04 2.0e-05 -6.0 -5.9 3.1e-09 -0.44 0.02 0.97 FALSE
7 The Cancer Genome Atlas Prostate Adenocarcinoma CEP120 0.10 0.14 blup 70 0.14 2.6e-14 9.4 -8.9 7.6e-19 -0.83 0.15 0.85 TRUE
8 The Cancer Genome Atlas Prostate Adenocarcinoma CSNK1G3 0.06 0.04 enet 10 0.05 2.3e-06 -6.2 -7.5 8.6e-14 -0.57 0.01 0.99 FALSE