[Hub]/) : Traits : Impedance of leg (left) : ← →

chr5:129,797,129-131,668,698

Best TWAS P=6.83e-15 · Best GWAS P=2.99e-13 conditioned to 7.3e-05

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	HINT1	0.10	0.07	enet	16	0.06	8.8e-06	6.4	7.8	6.8e-15	0.49	0.27	0.66	TRUE
2	GTEx	Artery Aorta	HINT1	0.07	0.07	enet	8	0.06	4.7e-04	6.9	7.5	4.4e-14	0.75	0.05	0.74	FALSE
3	GTEx	Artery Tibial	HINT1	0.11	0.04	enet	18	0.06	1.0e-05	6.6	7.0	3.2e-12	0.55	0.09	0.84	FALSE
5	GTEx	Cells Transformed fibroblasts	HINT1	0.10	0.06	lasso	2	0.05	2.1e-04	6.5	6.9	4.8e-12	0.57	0.14	0.82	FALSE
6	GTEx	Testis	RAPGEF6	0.50	0.35	lasso	4	0.32	6.5e-15	5.9	6.5	8.3e-11	0.89	0.06	0.94	FALSE
9	The Cancer Genome Atlas	Lung Adenocarcinoma	LYRM7	0.03	0.01	enet	10	0.02	7.5e-04	4.8	-6.4	1.7e-10	-0.74	0.01	0.86	FALSE
10	The Cancer Genome Atlas	Thyroid Carcinoma	HINT1	0.07	0.04	lasso	2	0.01	1.8e-02	6.4	6.4	1.7e-10	0.57	0.00	0.98	FALSE
8	The Cancer Genome Atlas	Brain Lower Grade Glioma	HINT1	0.06	0.03	enet	5	0.03	5.2e-04	4.7	5.8	8.0e-09	0.74	0.06	0.51	FALSE
4	GTEx	Artery Tibial	LYRM7	0.10	0.03	lasso	3	0.04	3.1e-04	5.6	-5.2	1.7e-07	-0.75	0.40	0.29	FALSE
7	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CDC42SE2	0.10	0.07	lasso	1	0.06	2.6e-04	5.1	-5.1	3.1e-07	-0.80	0.02	0.85	FALSE