[Hub]/) : Traits : Impedance of leg (left) : ← →

chr5:176,040,488-177,591,495

Best TWAS P=2.87e-26 · Best GWAS P=9.72e-36 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
28	The Cancer Genome Atlas	Prostate Adenocarcinoma	FGFR4	0.11	0.04	enet	19	0.06	8.7e-07	-12.5	10.6	2.9e-26	-0.87	0.00	1.00	TRUE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FGFR4	0.08	0.06	blup	46	0.07	2.5e-08	-12.5	6.9	4.0e-12	-0.75	0.00	1.00	TRUE
9	GTEx	Esophagus Gastroesophageal Junction	MXD3	0.17	0.12	lasso	3	0.08	9.5e-04	-5.7	-6.9	6.0e-12	0.34	0.08	0.06	TRUE
13	GTEx	Skin Sun Exposed Lower leg	PRELID1	0.06	0.02	enet	5	0.03	3.4e-03	-5.7	6.0	1.6e-09	-0.43	0.63	0.02	TRUE
4	GTEx	Artery Tibial	MXD3	0.12	0.13	enet	5	0.12	7.0e-10	-5.7	-5.2	2.0e-07	0.29	1.00	0.00	TRUE
27	The Cancer Genome Atlas	Lung Adenocarcinoma	MXD3	0.04	0.02	blup	41	0.02	5.6e-04	-6.3	-7.5	5.1e-14	0.52	0.02	0.91	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RAB24	0.14	0.06	enet	14	0.09	4.2e-11	6.9	7.5	8.4e-14	-0.31	1.00	0.00	FALSE
29	The Cancer Genome Atlas	Prostate Adenocarcinoma	MXD3	0.04	0.02	blup	40	0.03	2.8e-04	-5.7	-7.3	3.7e-13	0.48	0.02	0.96	FALSE
6	GTEx	Cells EBV-transformed lymphocytes	RAB24	0.37	0.26	lasso	6	0.24	1.7e-08	-6.7	7.1	9.8e-13	-0.52	0.97	0.00	FALSE
18	YFS	Blood	PRELID1	0.18	0.14	enet	18	0.18	4.0e-58	-5.5	6.9	4.1e-12	-0.39	1.00	0.00	FALSE
25	The Cancer Genome Atlas	Brain Lower Grade Glioma	MXD3	0.04	0.02	lasso	3	0.02	2.9e-03	-6.3	-6.9	6.3e-12	0.53	0.02	0.59	FALSE
22	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MXD3	0.05	0.00	lasso	6	0.00	6.9e-01	-7.3	-6.8	7.8e-12	0.22	0.02	0.10	FALSE
16	METSIM	Adipose	RAB24	0.05	0.02	lasso	4	0.02	1.2e-03	6.9	6.8	1.2e-11	-0.32	0.39	0.29	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	PRELID1	0.05	0.05	enet	10	0.05	1.8e-07	-6.5	6.7	2.2e-11	-0.52	1.00	0.00	FALSE
19	The Cancer Genome Atlas	Breast Invasive Carcinoma	MXD3	0.02	0.02	enet	4	0.02	1.8e-04	-6.6	-6.6	3.4e-11	0.52	0.21	0.75	FALSE
30	The Cancer Genome Atlas	Thyroid Carcinoma	MXD3	0.05	0.04	lasso	5	0.04	1.8e-04	-6.7	-6.6	5.2e-11	0.53	0.19	0.69	FALSE
14	GTEx	Stomach	MXD3	0.21	0.03	lasso	7	0.08	1.4e-04	-6.6	-6.5	9.8e-11	0.51	0.52	0.08	FALSE
2	GTEx	Adipose Visceral Omentum	MXD3	0.33	0.06	lasso	6	0.05	9.1e-04	-5.7	-6.1	8.7e-10	0.32	0.29	0.04	FALSE
15	GTEx	Testis	DBN1	0.10	0.00	lasso	6	0.00	4.6e-01	-5.1	6.0	2.0e-09	-0.45	0.06	0.04	FALSE
7	GTEx	Colon Sigmoid	MXD3	0.35	0.27	lasso	9	0.29	6.3e-11	-5.7	-5.9	3.8e-09	0.39	0.98	0.00	FALSE
12	GTEx	Pituitary	MXD3	0.25	0.20	lasso	6	0.16	7.5e-05	-5.1	-5.8	7.3e-09	0.46	0.37	0.06	FALSE
24	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PRELID1	0.33	0.08	enet	4	0.08	2.7e-05	-5.7	5.7	1.0e-08	-0.33	0.50	0.05	FALSE
26	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PRELID1	0.08	0.10	lasso	4	0.07	2.9e-04	-5.5	5.7	1.0e-08	-0.27	0.12	0.47	FALSE
5	GTEx	Brain Cerebellum	MXD3	0.28	0.31	lasso	2	0.30	1.6e-09	-5.7	-5.7	1.6e-08	0.32	0.90	0.00	FALSE
8	GTEx	Colon Transverse	PRELID1	0.31	0.28	lasso	4	0.26	1.1e-12	-5.7	5.6	1.7e-08	-0.34	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PRELID1	0.24	0.11	lasso	5	0.10	1.2e-11	-5.5	5.6	2.1e-08	-0.32	1.00	0.00	FALSE
11	GTEx	Heart Left Ventricle	MXD3	0.17	0.03	lasso	3	0.03	1.5e-02	-5.7	-5.5	3.5e-08	0.31	0.15	0.04	FALSE
10	GTEx	Esophagus Muscularis	MXD3	0.27	0.20	enet	10	0.24	1.6e-14	-5.7	-5.3	1.1e-07	0.33	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Colon Adenocarcinoma	PRELID1	0.09	0.01	blup	38	0.05	1.1e-03	-5.5	5.2	1.5e-07	-0.16	0.05	0.37	FALSE
3	GTEx	Artery Tibial	RAB24	0.18	0.09	lasso	3	0.07	2.3e-06	7.0	5.2	1.8e-07	-0.17	0.99	0.00	FALSE