TWAS
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About
Usage
Models
Genes
Traits
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Traits
:
Impedance of leg (left)
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chr5:178,525,779-180,195,862
Best TWAS P=9.36e-08 · Best GWAS P=2.06e-08 conditioned to 0.000873
178.6M
178.8M
179M
179.2M
179.4M
179.6M
179.8M
180M
180.2M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Esophagus Mucosa
RNF130
0.11
0.00
lasso
8
0.00
0.73100
-1.6
5.3
9.4e-08
-0.52
0.04
0.83
TRUE
2
METSIM
Adipose
LTC4S
0.05
0.04
lasso
4
0.02
0.00015
-5.3
-5.3
1.2e-07
0.91
0.02
0.98
FALSE