[Hub]/) : Traits : Impedance of arm (right) :

chr1:752,566-3,212,946

Best TWAS P=6.7e-12 · Best GWAS P=2.45e-12 conditioned to 0.377

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 1.9 5.3 9.9e-08 0.21 0.15 0.07 TRUE
2 GTEx Brain Cerebellar Hemisphere NADK 0.18 0.11 lasso 7 0.09 3.1e-03 6.1 6.2 4.0e-10 0.85 0.02 0.70 FALSE
3 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 6.9 -6.9 6.7e-12 -0.91 0.01 0.75 TRUE
4 GTEx Cells Transformed fibroblasts CDK11B 0.10 0.06 lasso 4 0.05 2.1e-04 -1.7 5.1 2.8e-07 0.85 0.02 0.90 FALSE
5 GTEx Esophagus Mucosa TMEM52 0.17 0.18 lasso 2 0.20 2.9e-13 5.7 -5.8 7.6e-09 -0.83 0.93 0.07 FALSE
6 GTEx Lung NADK 0.07 0.03 lasso 3 0.02 8.5e-03 -5.4 6.2 4.2e-10 0.94 0.02 0.93 FALSE
7 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 6.1 6.1 1.1e-09 0.79 0.04 0.85 FALSE
8 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 6.4 -6.3 3.2e-10 -0.84 0.34 0.66 FALSE
9 GTEx Pituitary NADK 0.21 0.09 enet 15 0.07 9.5e-03 6.4 5.2 2.6e-07 0.67 0.03 0.56 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic TMEM52 0.19 0.18 lasso 4 0.14 2.6e-08 -5.4 -5.9 4.3e-09 -0.92 0.03 0.97 FALSE
11 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 -6.1 -6.2 6.5e-10 -0.92 0.05 0.95 FALSE
12 GTEx Spleen RP3-395M20.9 0.42 0.14 lasso 3 0.15 1.1e-04 4.7 5.1 2.8e-07 0.00 0.03 0.66 TRUE
13 ROSMAP Brain Pre-frontal Cortex C1orf222 0.11 0.14 enet 18 0.14 1.8e-17 4.3 -5.8 9.0e-09 -0.70 0.99 0.01 FALSE
14 ROSMAP Brain Pre-frontal Cortex MMP23B 0.05 0.04 lasso 2 0.03 1.9e-04 5.3 5.3 1.2e-07 0.80 0.06 0.92 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC35E2 0.03 0.03 blup 35 0.01 7.0e-02 6.9 5.8 7.3e-09 0.95 0.00 0.99 FALSE
16 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM52 0.02 0.01 blup 37 0.02 6.6e-03 5.8 -6.2 7.3e-10 -0.91 0.01 0.81 FALSE
17 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC35E2 0.03 0.00 blup 34 0.01 5.3e-02 5.8 -5.4 8.3e-08 -0.82 0.02 0.47 FALSE