[Hub]/) : Traits : Impedance of arm (right) :

chr1:8,655,495-12,013,869

Best TWAS P=5.49e-19 · Best GWAS P=7.24e-17 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia KIF1B 0.25 0.00 lasso 5 0.02 1.1e-01 -5.2 -7.2 5.6e-13 -0.08 0.03 0.48 FALSE
2 GTEx Brain Cerebellar Hemisphere EXOSC10 0.23 0.10 lasso 3 0.12 6.4e-04 -4.8 -5.2 1.6e-07 -0.02 0.19 0.05 FALSE
3 GTEx Brain Cerebellum EXOSC10 0.33 0.16 lasso 6 0.18 3.8e-06 -5.0 -5.2 1.9e-07 -0.01 0.78 0.01 FALSE
4 GTEx Brain Cerebellum RP4-635E18.7 0.17 0.17 lasso 5 0.09 1.3e-03 -5.0 -5.2 2.3e-07 -0.02 0.38 0.03 FALSE
5 GTEx Cells Transformed fibroblasts UBE4B 0.09 0.00 enet 21 0.00 1.4e-01 -5.3 -5.9 4.4e-09 -0.10 0.04 0.34 FALSE
6 GTEx Esophagus Mucosa KIF1B 0.10 0.00 enet 17 0.01 1.2e-01 -5.7 -8.9 5.5e-19 -0.13 0.08 0.64 TRUE
7 GTEx Muscle Skeletal KIF1B 0.04 0.08 lasso 1 0.07 3.1e-07 -7.0 -7.0 2.6e-12 -0.13 0.89 0.09 FALSE
8 GTEx Nerve Tibial KIF1B 0.10 0.07 lasso 6 0.04 8.5e-04 -5.7 -6.1 8.8e-10 -0.12 0.83 0.12 FALSE
9 GTEx Thyroid KIF1B 0.13 0.14 lasso 5 0.16 5.3e-12 -7.0 -6.6 3.2e-11 -0.12 0.99 0.01 FALSE
10 METSIM Adipose MTOR 0.04 0.02 bslmm 434 0.02 1.5e-04 -4.6 -5.3 8.6e-08 -0.01 0.90 0.00 TRUE
11 NTR Blood KIF1B 0.11 0.08 enet 11 0.09 3.7e-28 7.9 7.3 3.1e-13 0.02 0.00 1.00 FALSE
12 ROSMAP Brain Pre-frontal Cortex KIF1B 0.06 0.08 bslmm 401 0.07 2.1e-09 -5.7 -5.2 2.2e-07 -0.13 1.00 0.00 FALSE
13 ROSMAP Brain Pre-frontal Cortex MTOR 0.07 0.05 bslmm 423 0.04 2.0e-06 -4.6 -5.2 2.2e-07 -0.02 1.00 0.00 FALSE
14 YFS Blood KIF1B 0.30 0.26 enet 49 0.29 7.8e-97 7.9 6.8 1.4e-11 0.03 0.01 0.99 FALSE
15 YFS Blood SPSB1 0.03 0.03 bslmm 425 0.03 1.5e-09 8.3 8.0 8.7e-16 0.96 0.00 1.00 TRUE
16 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MTOR 0.02 0.02 blup 54 0.02 5.4e-03 -5.0 -5.2 2.2e-07 0.00 0.03 0.85 FALSE
17 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma H6PD 0.31 0.06 blup 64 0.14 3.8e-06 3.3 -6.0 1.4e-09 -0.49 0.04 0.52 FALSE