[Hub]/) : Traits : Impedance of arm (right) :

chr10:101,348,343-103,362,569

Best TWAS P=7.8e-10 · Best GWAS P=5.12e-13 conditioned to 5.09e-07

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum RP11-179B2.2 0.13 0.02 lasso 3 0.03 6.5e-03 -6.0 -5.7 1.2e-08 0.02 0.01 0.98 FALSE
2 GTEx Artery Aorta RP11-179B2.2 0.16 0.11 lasso 2 0.09 7.6e-06 -6.0 -5.7 1.0e-08 0.02 0.01 0.99 FALSE
3 GTEx Artery Tibial RP11-179B2.2 0.11 0.09 lasso 4 0.08 8.8e-07 -6.0 -6.0 1.5e-09 0.03 0.01 0.99 FALSE
4 GTEx Brain Cerebellum RP11-179B2.2 0.37 0.21 lasso 4 0.20 1.4e-06 -6.1 -5.8 5.5e-09 0.02 0.01 0.99 FALSE
5 GTEx Brain Frontal Cortex BA9 RP11-179B2.2 0.22 0.15 lasso 2 0.11 7.2e-04 -6.1 -5.7 1.2e-08 0.01 0.01 0.96 FALSE
6 GTEx Breast Mammary Tissue RP11-179B2.2 0.11 0.09 lasso 2 0.07 1.8e-04 -6.0 -5.3 9.9e-08 0.02 0.01 0.99 FALSE
7 GTEx Esophagus Muscularis RP11-179B2.2 0.15 0.16 lasso 3 0.16 8.1e-10 -6.2 -6.1 7.8e-10 0.03 0.00 1.00 TRUE
8 GTEx Heart Left Ventricle RP11-179B2.2 0.15 0.18 enet 2 0.14 4.8e-08 -6.1 -6.0 1.7e-09 0.02 0.00 1.00 FALSE
9 GTEx Lung RP11-179B2.2 0.18 0.12 lasso 3 0.12 1.7e-09 -6.1 -5.7 1.3e-08 0.02 0.01 0.99 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic RP11-179B2.2 0.27 0.15 enet 36 0.15 2.0e-08 -6.1 -5.9 3.3e-09 0.00 0.00 1.00 FALSE
11 ROSMAP Brain Pre-frontal Cortex PKD2L1 0.18 0.12 enet 16 0.16 4.5e-20 -4.4 -5.2 2.1e-07 0.54 1.00 0.00 TRUE
12 The Cancer Genome Atlas Colon Adenocarcinoma MRPL43 0.07 0.02 blup 52 0.00 1.7e-01 -5.9 5.4 6.4e-08 -0.03 0.01 0.86 FALSE