Best TWAS P=9.78e-16 · Best GWAS P=2.31e-18 conditioned to 0.00547
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | AMPD3 | 0.20 | 0.02 | lasso | 8 | 0.01 | 5.5e-02 | 5.1 | -5.2 | 2.5e-07 | -0.22 | 0.30 | 0.04 | FALSE |
| 2 | GTEx | Prostate | SBF2 | 0.21 | 0.05 | lasso | 7 | 0.03 | 6.7e-02 | -7.2 | -7.9 | 2.6e-15 | -0.86 | 0.05 | 0.74 | FALSE |
| 3 | GTEx | Testis | SBF2 | 0.10 | 0.01 | lasso | 5 | 0.02 | 5.0e-02 | -6.7 | 7.2 | 4.9e-13 | 0.82 | 0.09 | 0.76 | FALSE |
| 4 | METSIM | Adipose | AMPD3 | 0.06 | 0.03 | enet | 14 | 0.05 | 7.8e-08 | -6.2 | -5.7 | 1.2e-08 | -0.08 | 0.96 | 0.00 | TRUE |
| 5 | NTR | Blood | ADM | 0.04 | 0.04 | enet | 13 | 0.04 | 1.6e-13 | -7.2 | 8.0 | 1.5e-15 | 0.88 | 0.14 | 0.86 | FALSE |
| 6 | ROSMAP | Brain Pre-frontal Cortex | SBF2-AS1 | 0.03 | 0.00 | bslmm | 362 | 0.01 | 4.4e-03 | 2.4 | -6.6 | 5.3e-11 | -0.59 | 0.03 | 0.71 | FALSE |
| 7 | YFS | Blood | ADM | 0.08 | 0.11 | enet | 25 | 0.12 | 9.4e-36 | -7.4 | 8.0 | 9.8e-16 | 0.85 | 0.97 | 0.03 | TRUE |