TWAS hub - ZCRB1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1010	0.0270	5.6e-11	0.126	0.106	0.125	0.119	0.126	4.0e-15	7.3e-13	5.3e-15	2.4e-14	3.8e-15
2	GTEx	Adipose Subcutaneous	0.1120	0.0360	9.9e-06	0.088	NA	0.079	NA	0.045	1.2e-07	NA	4.9e-07	NA	1.4e-04
3	GTEx	Artery Aorta	0.1510	0.0500	1.4e-05	0.092	NA	0.075	NA	0.107	8.8e-06	NA	6.4e-05	NA	1.7e-06
4	GTEx	Artery Tibial	0.0768	0.0291	1.2e-04	0.079	NA	0.074	NA	0.092	8.9e-07	NA	1.9e-06	NA	1.2e-07
5	GTEx	Brain Cerebellar Hemisphere	0.3270	0.0970	3.6e-06	0.318	NA	0.136	NA	0.306	6.5e-09	NA	2.4e-04	NA	1.3e-08
6	GTEx	Brain Cerebellum	0.1300	0.0540	3.0e-03	0.066	NA	-0.001	NA	0.019	5.3e-03	NA	3.4e-01	NA	9.0e-02
7	GTEx	Brain Hippocampus	0.2202	0.0980	8.1e-03	0.023	NA	-0.010	NA	0.012	9.3e-02	NA	6.3e-01	NA	1.6e-01
8	GTEx	Cells Transformed fibroblasts	0.0930	0.0320	1.1e-04	0.026	NA	0.076	NA	0.036	4.8e-03	NA	2.4e-06	NA	1.0e-03
9	GTEx	Colon Sigmoid	0.1310	0.0490	1.6e-03	0.146	NA	0.110	NA	0.116	7.8e-06	NA	1.1e-04	NA	7.0e-05
10	GTEx	Esophagus Muscularis	0.1290	0.0440	6.2e-05	0.098	NA	0.027	NA	0.076	1.5e-06	NA	8.7e-03	NA	2.4e-05
11	GTEx	Lung	0.0961	0.0293	1.4e-06	0.145	NA	0.128	NA	0.123	3.1e-11	NA	5.6e-10	NA	1.1e-09
12	GTEx	Muscle Skeletal	0.0525	0.0195	3.3e-04	0.087	NA	0.058	NA	0.065	7.2e-09	NA	2.5e-06	NA	6.0e-07
13	GTEx	Prostate	0.1930	0.0760	3.9e-03	0.181	NA	0.183	NA	0.173	2.6e-05	NA	2.4e-05	NA	4.0e-05
14	GTEx	Testis	0.3060	0.0790	1.9e-06	0.145	NA	0.191	NA	0.150	5.4e-07	NA	6.8e-09	NA	3.7e-07
15	TCGA	Brain Lower Grade Glioma	0.0400	0.0298	6.3e-03	0.009	0.011	0.008	NA	0.005	2.8e-02	1.8e-02	4.2e-02	NA	7.7e-02
16	TCGA	Prostate Adenocarcinoma	0.0658	0.0379	3.3e-06	0.029	0.059	0.039	NA	0.048	4.2e-04	8.0e-07	5.4e-05	NA	8.4e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16
Primary Biliary Cirrhosis	9.0	12.9	25.2	3.7	3.5	2.5	3.4	4.0	2.9	1.5	3.1	4.0	5.0	4.9	4.2	3.9	-1.8	4.9	1.3
Rheumatoid Arthritis	5.6	7.7	12.6	2.7	3.5	3.1	2.5	3.1	2.6	1.4	1.2	3.5	3.1	3.2	3.5	3.0	-2.7	2.5	0.8
Heart disease (mother)	5.0	6.1	12.5	-2.1	-3.2	-2.6	-2.7	-2.5	-2.0	-1.0	-1.1	-3.5	-2.9	-3.1	-3.4	-2.4	1.8	-2.2	-0.1
Hand grip strength (right)	4.6	12.6	17.5	3.9	3.5	3.6	4.0	4.0	3.5	2.2	3.5	4.2	4.1	4.1	4.0	3.9	-1.5	3.6	1.6
Hypothyroidism (self reported)	4.5	10.3	21.5	2.9	2.9	4.6	3.4	3.1	3.8	3.4	2.5	3.3	3.6	3.7	3.2	3.1	-2.0	3.1	1.3
Taking other prescription medications	4.2	6.5	13.2	2.7	0.1	2.7	2.9	2.4	2.7	2.3	3.6	1.6	3.3	3.2	1.6	2.5	0.5	3.6	2.0
Impedance of arm (right)	4.1	18.9	31.4	-4.2	-3.9	-4.5	-4.4	-4.6	-3.7	-2.0	-5.1	-5.3	-5.6	-5.5	-5.1	-4.3	1.0	-5.4	-1.1
Hand grip strength (left)	4.0	10.5	16.5	3.4	3.6	3.1	3.4	3.6	2.9	1.7	2.8	4.1	3.7	3.9	3.9	3.5	-2.4	3.3	0.9
Impedance of leg (right)	4.0	19.5	35.5	-4.6	-2.4	-4.0	-4.5	-4.6	-4.5	-3.2	-5.0	-4.6	-6.0	-5.9	-4.4	-4.6	0.7	-5.8	-2.3
Medication: Levothyroxine sodium	3.9	6.5	16.2	2.5	2.3	4.0	3.1	2.5	2.9	2.1	2.5	2.3	2.7	2.8	2.2	2.6	-0.7	2.7	1.5
Comparative body size at age 10	3.7	10.2	16.6	4.0	2.6	3.2	3.4	4.0	2.8	1.3	2.9	3.1	4.1	3.7	3.0	4.0	-0.5	3.8	2.5
Impedance of arm (left)	3.6	16.7	28.8	-4.0	-3.4	-4.2	-4.2	-4.4	-3.4	-1.8	-4.9	-4.8	-5.4	-5.3	-4.6	-4.1	1.0	-5.1	-1.2
Impedance of whole body	3.5	17.9	32.6	-4.3	-2.6	-4.0	-4.2	-4.4	-3.8	-2.3	-5.2	-4.7	-5.7	-5.7	-4.5	-4.3	0.8	-5.7	-1.6
Impedance of leg (left)	3.3	16.1	28.9	-4.5	-1.8	-3.7	-4.5	-4.3	-4.2	-2.8	-5.0	-3.5	-5.1	-5.1	-3.4	-4.3	-0.5	-5.4	-2.7
Medication: Allopurinol	3.3	4.4	12.5	1.2	2.7	1.2	1.4	1.6	1.2	0.6	1.3	3.4	3.0	2.9	3.5	1.5	-1.9	2.2	-0.9
Medication: Atenolol	3.1	3.9	6.1	-2.4	-2.1	-1.6	-1.8	-2.4	-2.3	-1.9	-1.4	-1.6	-2.4	-2.3	-1.7	-2.5	-0.4	-2.1	-1.4
Supplements: Glucosamine	2.7	3.5	9.2	-1.4	-3.0	-1.3	-1.7	-1.6	-2.4	-2.7	0.2	-2.5	-1.6	-1.9	-2.6	-1.6	0.7	-1.2	0.2
Had other major operations	2.6	3.2	10.6	2.1	0.6	1.6	2.1	2.0	1.8	0.8	3.2	1.2	2.4	1.8	1.1	2.0	-0.1	1.7	1.7
Hypothyroidism/myxoedema (self-reported)	2.3	4.6	7.9	2.1	1.6	2.8	2.6	2.0	2.4	1.8	2.2	2.1	2.6	2.6	2.0	2.0	-1.2	2.4	1.1
Health satisfaction	2.3	3.0	4.5	2.0	1.7	1.8	2.1	1.9	2.0	1.4	1.9	1.4	1.6	1.6	1.4	2.0	0.9	2.1	1.5
Illnesses of father: Heart disease	2.3	3.1	6.6	-1.4	-2.1	-1.5	-1.5	-1.5	-1.6	-1.0	-1.4	-2.4	-2.5	-2.6	-2.2	-1.5	1.3	-2.0	0.1
BMI	2.2	12.7	24.5	4.2	1.2	3.1	4.0	4.1	3.5	2.2	4.5	3.1	4.4	4.5	2.9	4.1	0.3	5.0	2.5
Diabetes (father)	2.2	2.7	12.3	1.3	-1.2	0.2	1.0	0.5	0.0	-0.9	1.7	-2.4	-0.5	-1.0	-2.2	0.9	3.5	0.1	3.1
Falls in the last year	2.2	3.0	9.8	-2.0	-3.1	-2.2	-1.7	-2.1	-2.1	-1.9	-0.9	-1.4	-1.1	-1.3	-1.4	-2.1	0.2	-1.1	-1.2
Hair/balding pattern: Pattern 4	2.1	5.2	10.9	2.9	2.1	3.3	2.7	2.8	2.8	2.4	1.7	0.3	1.5	1.5	0.3	2.9	1.1	2.1	3.0
Pulse wave reflection index	2.1	2.6	5.3	1.9	2.3	1.9	2.2	2.2	1.9	1.7	1.1	1.0	1.2	0.9	0.8	2.0	1.0	0.7	1.7
Reason for reducing amount of alcohol drunk: Health precaution	2.1	2.4	4.6	1.3	2.0	1.6	1.0	1.5	1.1	0.8	0.5	2.1	1.7	1.9	2.1	1.4	-2.1	1.7	-0.0
Illnesses of mother	2.0	2.5	8.7	0.5	2.2	0.6	1.0	1.0	1.1	1.0	-0.1	2.9	1.5	2.0	3.0	0.9	-1.8	0.7	-1.5
Gout (self-reported)	2.0	2.8	8.1	0.7	2.8	1.3	1.0	1.2	1.2	0.9	1.1	2.7	1.9	1.9	2.8	1.1	-1.4	1.2	-1.2
Number of full brothers	2.0	2.5	7.4	1.6	0.2	2.7	2.3	1.5	1.9	1.8	1.8	-0.1	0.9	0.8	-0.2	1.4	1.9	1.2	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.0	2.4	4.5	1.6	2.1	1.2	1.2	2.0	1.6	1.4	1.1	1.8	1.8	1.8	1.7	1.9	-0.8	1.1	0.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.0	2.3	8.1	-0.1	-2.2	0.3	0.1	-0.8	0.2	1.6	0.7	-2.4	-1.1	-1.6	-2.5	-0.5	2.9	-0.6	1.9
Age started oral contraceptive pill	2.0	2.5	6.2	-1.7	-2.5	-1.5	-2.3	-1.8	-1.5	-0.7	-0.8	-1.7	-1.5	-1.5	-1.6	-1.8	1.2	-1.0	-0.9
Birth weight of first child	1.9	3.4	5.2	1.9	1.6	2.3	2.1	2.1	2.0	1.3	2.2	2.1	1.8	2.1	2.1	2.0	-0.3	1.7	0.7
Arm fat-free mass (right)	1.9	9.9	17.5	3.3	2.3	2.6	3.0	3.5	2.5	0.9	4.0	3.7	4.2	4.1	3.6	3.4	-0.7	4.1	1.1
Migraine (self-reported)	1.9	2.4	4.8	-2.1	-1.7	-1.1	-2.2	-2.1	-1.4	-0.4	-0.8	-1.0	-1.2	-1.1	-0.9	-2.1	-1.8	-1.4	-1.9
Tinnitus: Yes, now most or all of the time	1.9	2.2	7.1	0.1	-2.5	-0.4	-0.4	-0.5	-0.5	-0.2	0.9	-2.6	-1.3	-1.2	-2.7	-0.3	2.5	-0.3	2.0
Medication: Paracetamol	1.9	3.0	8.0	1.4	0.8	1.0	1.7	1.5	0.5	-0.3	0.2	2.7	2.8	2.6	2.5	1.5	-0.2	2.8	0.1
Sitting height	1.8	12.4	19.1	4.1	4.4	3.6	3.5	4.3	4.0	3.0	2.9	3.7	3.4	3.6	3.6	4.3	-0.2	3.5	2.1
Medication: Paracetamol	1.8	3.0	8.2	1.4	1.5	1.0	1.7	1.6	0.9	0.3	0.2	2.9	2.8	2.5	2.6	1.5	-0.4	2.4	-0.0
Arm predicted mass (right)	1.8	9.2	17.1	3.2	2.0	2.5	2.9	3.3	2.4	0.9	3.9	3.6	4.1	4.0	3.4	3.2	-0.6	4.1	1.1
Leg fat-free mass (right)	1.8	9.7	17.8	3.4	1.5	2.6	3.1	3.3	3.0	1.9	3.8	3.3	4.2	4.2	3.1	3.4	-0.3	4.2	1.7
Loneliness, isolation	1.8	2.5	7.0	-0.7	-2.0	-0.9	-1.2	-1.2	-0.9	-0.6	0.2	-2.6	-1.8	-2.1	-2.6	-1.0	2.1	-1.3	1.3
Leg predicted mass (right)	1.8	9.4	17.6	3.4	1.4	2.5	3.0	3.3	2.9	1.8	3.8	3.2	4.1	4.1	3.0	3.3	-0.2	4.2	1.8
Medication: Metformin	1.7	2.4	5.0	1.9	0.8	1.6	1.7	1.9	1.4	0.6	2.1	1.0	1.6	2.0	0.8	1.9	1.1	2.2	1.2
Osteoporosis (self-reported)	1.7	2.1	5.5	-2.0	-1.5	-1.8	-1.7	-1.9	-1.7	-1.5	-0.9	-0.1	-0.2	-0.2	-0.0	-2.0	-1.4	-0.4	-2.4
Medication: Co-codamol	1.6	1.9	4.7	1.1	0.7	1.2	1.1	1.3	0.4	-0.2	0.5	1.9	2.2	2.0	2.0	1.2	-1.6	1.6	-0.1
Birth weight	1.6	3.5	6.0	2.1	1.8	2.4	2.3	2.3	2.1	1.6	2.1	1.7	1.8	1.6	1.7	2.2	0.5	1.3	1.4
Mineral and other dietary supplements	1.6	2.1	5.0	1.4	2.2	0.9	1.5	1.4	2.0	2.2	1.1	1.4	1.3	1.3	1.4	1.5	0.5	1.4	0.8
Financial situation satisfaction	1.6	2.0	6.1	0.7	2.4	0.2	1.1	1.1	1.2	1.0	-0.1	2.5	1.1	1.4	2.3	1.0	-1.8	0.9	-0.7
Arm fat-free mass (left)	1.6	8.3	15.4	2.9	1.9	2.2	2.7	3.1	2.1	0.8	3.7	3.6	3.9	3.9	3.4	2.9	-1.1	3.9	0.8
Neuroticism (2016)	1.5	2.2	3.8	-1.7	-0.7	-1.5	-1.7	-1.9	-1.6	-1.2	-1.9	0.2	-1.2	-1.1	-0.0	-1.8	-2.0	-1.3	-1.9
Type 2 Diabetes (T2D) (2018)	1.5	2.9	5.3	2.1	0.7	1.3	2.1	1.8	1.8	1.2	2.3	0.9	1.7	1.7	0.7	1.9	2.0	2.0	1.7
Leg fat-free mass (left)	1.5	8.0	15.5	3.4	1.0	2.3	3.0	3.2	2.7	1.5	3.7	2.5	3.6	3.7	2.4	3.2	0.3	3.9	2.1
Townsend deprivation index at recruitment	1.5	2.1	3.9	-1.6	-1.3	-1.7	-1.5	-1.6	-2.0	-1.8	-2.0	-0.8	-1.2	-1.2	-0.6	-1.6	-0.2	-1.5	-1.4
Body mass index (BMI)	1.5	6.3	18.6	3.0	-0.7	1.9	2.7	2.6	1.9	0.7	4.3	1.2	3.1	3.0	1.1	2.7	1.0	3.8	2.6
Leg predicted mass (left)	1.5	8.0	15.5	3.3	1.0	2.3	3.0	3.2	2.7	1.5	3.7	2.5	3.6	3.7	2.4	3.2	0.4	3.9	2.0
Diabetes (self-reported)	1.5	2.3	5.1	1.9	0.1	1.1	1.7	1.6	1.3	0.4	2.1	0.7	2.0	2.0	0.5	1.8	0.9	2.3	1.7
Worry too long after embarrassment	1.5	2.5	5.0	-2.2	-0.5	-1.9	-2.2	-2.1	-1.4	-0.8	-1.9	-0.4	-0.9	-1.0	-0.3	-2.1	-1.6	-1.4	-2.1
Whole body fat-free mass	1.5	8.4	15.5	3.0	1.8	2.3	2.8	3.1	2.4	1.1	3.7	3.5	3.9	3.9	3.3	3.0	-0.7	3.9	1.0
Whole body water mass	1.5	8.8	16.2	3.1	1.8	2.3	2.8	3.2	2.4	1.1	3.7	3.5	4.0	4.0	3.3	3.1	-0.8	3.9	1.1
Average weekly champagne plus white wine intake	1.5	2.1	6.8	1.5	1.4	2.6	1.8	1.6	1.8	2.1	0.8	0.9	0.9	1.0	1.0	1.5	0.0	0.9	1.0
Basal metabolic rate	1.5	8.2	15.3	3.1	1.4	2.2	2.8	3.1	2.4	1.0	3.8	3.2	3.8	3.9	3.0	3.1	-0.5	3.9	1.3
Alcohol drinker status: Previous	1.5	1.8	4.5	1.2	1.3	2.1	1.0	1.2	1.7	1.1	1.9	1.2	1.5	1.4	1.2	1.2	-0.5	1.3	0.3
Arm predicted mass (left)	1.5	7.5	15.7	2.9	1.6	2.1	2.6	3.0	2.1	0.7	4.0	3.2	3.7	3.7	3.0	2.9	-0.6	3.7	1.0
Hearing difficulty/problems: Yes	1.4	2.2	11.8	0.2	-1.4	0.8	0.3	0.0	0.3	0.7	0.5	-2.2	-1.5	-1.4	-2.4	0.1	3.4	-0.7	2.0
Diabetes diagnosed by doctor	1.4	2.3	5.9	1.9	-0.2	1.1	1.8	1.5	1.1	-0.0	2.4	0.5	1.8	1.8	0.4	1.7	1.0	2.3	1.6
Verbal and Numeric Reasoning (VNR)	1.3	3.1	7.8	-1.7	-0.5	-1.2	-1.5	-1.9	-1.1	-0.8	-0.5	-2.4	-2.6	-2.8	-2.3	-1.8	1.1	-2.6	-0.1
Trunk fat-free mass	1.3	7.4	14.4	2.5	2.0	2.1	2.3	2.7	2.0	0.7	3.3	3.8	3.7	3.8	3.6	2.6	-1.3	3.5	0.2
Hair/balding pattern: Pattern 3	1.3	1.9	7.3	-2.1	-0.5	-0.8	-1.5	-1.6	-1.3	-1.0	-0.9	0.5	-1.0	-0.7	0.5	-1.9	-1.7	-1.3	-2.7
Shortness of breath walking on level ground	1.3	1.6	4.5	0.9	1.0	1.9	1.0	1.1	1.6	2.1	-0.0	1.4	1.1	1.3	1.3	1.1	0.4	1.4	0.2
Medication: Seretide 50 evohaler	1.3	1.5	5.2	1.2	0.1	1.7	1.6	1.1	1.1	0.4	1.9	0.3	0.8	0.7	0.4	1.2	2.3	1.1	1.4
Chest pain or discomfort	1.3	1.9	9.2	-0.5	-1.4	-0.2	-0.5	-0.9	-0.4	-0.1	0.3	-2.2	-1.6	-1.8	-2.2	-0.7	3.0	-1.0	1.2
Ever had stillbirth, spontaneous miscarriage or termination	1.3	1.4	4.7	0.7	0.3	0.2	0.6	0.4	0.5	0.2	0.8	-1.9	-1.3	-1.4	-1.8	0.6	2.0	-1.0	2.2
Supplements: Fish oil (including cod liver oil)	1.3	1.8	5.7	-1.4	-1.8	-1.3	-1.5	-1.4	-2.0	-2.4	-1.0	-0.6	-0.7	-0.8	-0.6	-1.4	-0.6	-0.7	-1.3
Average weekly beer plus cider intake	1.3	1.8	3.8	-1.7	-1.7	-1.1	-2.0	-1.4	-1.4	-1.8	-0.7	-0.9	-1.3	-1.0	-1.0	-1.6	-1.2	-0.7	-1.5
Fractured/broken bones in last 5 years	1.3	1.7	3.4	-1.6	-1.2	-1.0	-1.4	-1.6	-0.9	0.1	-1.1	-1.4	-1.9	-1.6	-1.5	-1.6	0.1	-1.5	-0.8
Respiratory disease	1.2	2.7	5.4	2.0	0.1	1.6	1.5	1.8	1.5	0.6	2.1	1.1	2.2	2.2	1.5	1.9	1.3	2.3	1.2
Had menopause	1.2	1.5	3.6	-1.2	-1.9	-1.7	-1.4	-1.3	-1.5	-1.4	-0.9	-1.0	-0.7	-0.8	-0.9	-1.3	0.7	-0.6	-0.9
Weight	1.2	5.8	14.6	2.9	0.0	1.8	2.5	2.6	1.8	0.5	3.8	1.8	3.2	3.1	1.7	2.7	0.3	3.6	1.9
Lung cancer (father)	1.2	1.4	3.2	1.4	0.7	0.8	0.9	1.4	0.6	-0.9	1.1	1.1	1.8	1.7	1.2	1.4	-0.3	1.8	0.6
Trunk predicted mass	1.2	6.9	14.0	2.3	2.0	2.0	2.2	2.6	1.8	0.6	3.2	3.7	3.5	3.6	3.5	2.4	-1.4	3.3	0.1
Illnesses of father: None of the above (group 1)	1.2	1.5	4.2	-0.5	1.1	-0.7	-0.5	-0.2	-0.4	-1.0	-0.7	1.9	1.3	1.4	2.0	-0.3	-1.9	0.9	-2.0
Miserableness	1.2	2.2	4.7	-1.7	-2.2	-1.5	-1.9	-2.2	-1.4	-0.5	-0.4	-1.6	-0.9	-1.5	-1.5	-1.9	0.6	-1.3	-0.8
Number of operations (self-reported)	1.2	1.8	7.5	1.6	0.2	1.0	1.5	1.2	1.3	0.5	2.7	-0.1	1.2	0.9	0.1	1.4	1.4	1.6	1.6
Ovarian Cancer	1.1	1.5	3.4	-1.3	0.4	-1.5	-1.4	-1.3	-1.5	-1.4	-1.8	0.4	-0.2	-0.3	0.3	-1.3	-1.5	-0.8	-1.8
Tinnitus: Yes, but not now, but have in the past	1.1	1.1	2.4	1.3	1.2	0.2	1.0	1.2	0.8	0.5	1.2	1.1	1.5	1.2	0.9	1.3	0.3	1.4	0.9
High blood pressure (mother)	1.1	1.5	3.2	-1.0	-1.7	-0.5	-1.5	-1.3	-1.0	-0.4	-1.2	-1.6	-1.6	-1.7	-1.8	-1.2	0.7	-0.8	0.1
Pain all over the body in last month	1.1	1.2	4.7	-1.2	-0.2	-1.0	-1.0	-1.0	-1.5	-2.2	-0.1	-0.6	-1.0	-1.2	-0.4	-1.1	-0.0	-1.2	-1.3
Chronic bronchitis/emphysema (mother)	1.1	1.3	4.3	-0.4	-0.9	-1.2	-0.2	-0.6	-0.9	-1.8	0.8	-2.1	-1.3	-1.4	-1.9	-0.5	0.8	-0.7	0.9
Forced vital capacity (FVC), Best measure	1.1	4.1	11.6	1.0	2.5	1.7	1.0	1.4	1.5	1.6	0.5	3.4	2.2	2.5	3.2	1.3	-2.9	1.5	-1.4
Medication: Blood pressure	1.1	1.9	6.3	-1.2	-2.5	-1.3	-1.7	-1.5	-1.8	-1.7	-1.0	-1.5	-0.9	-1.1	-1.3	-1.4	-0.1	-0.7	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.1	1.3	2.9	-1.0	-1.7	-1.4	-0.9	-1.1	-0.9	-0.6	0.5	-1.7	-1.0	-1.3	-1.7	-1.1	0.3	-1.3	0.1
Irritability	1.1	1.8	5.2	-0.6	-2.3	-0.8	-0.8	-1.1	-0.5	0.3	0.1	-2.1	-1.2	-1.6	-2.1	-0.9	2.0	-1.4	1.0
Major Depression (MDD)	1.0	1.2	4.7	-0.5	-2.1	-0.7	-0.4	-0.8	-0.4	-0.3	0.5	-1.7	-0.9	-0.8	-1.8	-0.7	2.2	0.0	0.8
Body Mass Index (BMI) (2010)	1.0	1.3	4.4	1.1	0.4	1.5	1.2	1.1	1.3	1.0	2.1	0.8	1.1	1.3	0.7	1.1	-0.2	1.4	0.7
Fasting Glucose	1.0	1.2	3.2	1.3	1.8	0.9	1.4	1.3	0.8	0.5	0.9	1.2	1.0	0.8	1.1	1.4	1.0	0.6	1.0
LDL Cholesterol	1.0	1.6	7.8	-1.0	-0.6	-1.7	-1.1	-1.2	-2.0	-2.8	-0.6	-0.9	-1.0	-1.2	-0.7	-1.1	-0.1	-1.0	-0.8
Lung FEV1/FVC ratio	1.0	5.1	9.4	-2.8	-1.0	-2.4	-2.7	-2.5	-2.1	-1.4	-2.5	-1.4	-2.8	-2.6	-1.4	-2.6	-0.7	-3.1	-2.3
Number of treatments/medications taken	1.0	1.8	6.0	1.4	-1.4	1.3	1.4	1.2	0.7	-0.0	1.9	0.5	1.9	1.6	0.4	1.2	0.7	2.5	1.5
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	3.1	-1.5	-0.7	-1.1	-0.9	-1.1	-1.1	-0.9	-1.0	-0.3	-1.8	-1.5	-0.5	-1.2	-0.7	-1.7	-1.4
Exposure to tobacco smoke at home	1.0	1.1	4.5	-1.1	-2.1	-0.5	-1.1	-1.3	-1.0	-0.9	-0.1	-1.3	-0.6	-0.6	-1.3	-1.2	-0.9	-0.4	-0.4
Medication: Amlodipine	1.0	1.4	4.8	1.1	-0.1	1.0	0.8	1.0	1.3	1.7	0.5	1.1	1.4	1.6	1.1	1.0	-0.2	2.2	0.6
Suffer from ‘nerves’	1.0	1.6	4.7	-1.4	-0.1	-1.1	-0.8	-1.2	-1.1	-1.4	-0.9	-1.2	-2.2	-1.7	-1.1	-1.3	-0.1	-1.8	-0.8
Ever had bowel cancer screening	1.0	1.1	7.8	1.1	0.1	1.1	1.3	1.1	0.6	-0.1	1.0	-0.3	0.0	-0.1	-0.3	1.1	2.8	0.3	1.4
Arm fat mass (left)	1.0	4.0	13.5	2.4	-1.3	1.0	1.9	2.0	1.3	0.4	3.7	0.5	2.4	2.3	0.5	2.1	1.1	3.1	2.4
Wears glasses or contact lenses	1.0	1.1	3.1	-0.2	-1.8	-1.3	-1.3	-0.6	-1.3	-1.3	-0.4	-1.4	-0.4	-0.6	-1.4	-0.4	1.5	-0.2	0.6
Pain type(s) experienced in last month: Hip pain	1.0	1.3	5.9	-1.4	-0.5	-1.4	-1.7	-1.3	-1.2	-0.1	-2.4	0.5	-0.3	-0.5	0.3	-1.3	-0.7	-0.5	-1.4
Schizophrenia vs Biploar Disorder	0.9	1.2	2.6	1.3	1.4	1.0	1.6	1.5	0.0	-1.4	1.2	1.1	0.8	0.8	1.0	1.4	-0.3	0.7	0.7
Blood Eosinophil Count	0.9	7.3	14.8	2.7	2.6	1.3	2.6	2.9	2.3	1.3	1.8	3.4	3.9	3.8	3.5	2.8	-1.8	3.2	0.5
Lung FVC	0.9	4.3	14.0	0.6	2.0	1.1	1.0	1.1	0.4	-0.0	0.4	3.6	2.6	2.6	3.5	0.8	-3.7	2.0	-1.9
Average weekly spirits intake	0.9	1.1	4.3	-0.0	1.5	-0.0	0.7	0.4	0.4	0.1	-0.4	1.8	0.9	0.7	1.9	0.2	-2.1	0.2	-1.1
Hair/balding pattern: Pattern 2	0.9	1.2	3.0	1.4	-0.5	0.8	0.9	1.1	1.3	1.2	1.7	0.1	0.8	0.9	0.1	1.2	1.2	1.1	1.4
Heart attack	0.9	1.1	4.2	0.9	0.3	1.5	1.2	1.0	1.4	2.1	0.4	0.2	0.6	0.5	0.3	0.9	1.8	0.6	0.8
Hayfever/allergic rhinitis (self-reported)	0.9	1.2	5.0	-1.2	-0.6	-1.8	-0.8	-1.2	-1.0	-0.6	-2.2	-0.0	-0.8	-0.9	-0.2	-1.2	-0.8	-1.4	-1.1
Length of working week for main job	0.9	1.0	2.3	-1.3	-0.7	-0.9	-0.7	-1.1	-0.9	-0.9	-0.4	-0.8	-1.5	-1.5	-0.8	-1.2	0.5	-1.4	-0.8
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	3.6	-0.7	-1.8	-1.1	-1.1	-0.9	-1.3	-1.2	-1.1	-1.8	-1.5	-1.5	-1.9	-0.8	0.6	-0.7	0.3
Asthma (self-reported)	0.9	1.8	4.7	1.3	-0.3	1.3	0.9	1.1	1.1	0.5	1.9	1.0	1.8	1.8	1.3	1.2	1.5	2.2	0.6
Supplements: Calcium	0.9	1.0	5.2	-0.8	-2.3	-0.8	-0.8	-1.1	-1.1	-0.8	-0.9	-1.3	-0.9	-0.8	-1.0	-1.0	0.2	-0.6	-0.2
Waist Hip Ratio (WHR)	0.8	3.5	6.0	-2.0	-1.4	-2.4	-1.9	-2.1	-1.8	-0.9	-1.6	-1.9	-2.3	-2.4	-1.9	-2.1	0.7	-2.4	-0.9
Relative age of first facial hair	0.8	1.6	8.0	-1.5	-0.8	-1.8	-1.1	-1.5	-1.1	-0.2	-2.8	0.2	-0.2	-0.6	0.2	-1.5	-0.2	-1.0	-1.5
Eye problems/disorders: Diabetes related eye disease	0.8	0.9	1.6	-1.3	-0.3	-0.6	-1.1	-1.2	-0.9	-1.0	-0.3	-0.7	-1.0	-1.0	-0.8	-1.3	-0.4	-1.3	-0.7
Medication for hormone replacement therapy	0.8	0.9	2.4	-1.2	-1.3	-0.5	-1.1	-1.4	-1.0	-0.6	-0.2	-0.9	-0.2	-0.5	-1.0	-1.4	-1.5	-0.4	-0.4
Relative age voice broke	0.8	1.3	8.1	-1.3	0.2	-0.8	-1.3	-1.0	-0.6	0.7	-2.8	0.4	-0.6	-0.4	0.3	-1.1	-0.9	-0.8	-1.7
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	11.2	-0.1	-1.0	-0.5	-0.4	-0.6	0.5	1.5	0.6	-1.3	-0.4	-0.8	-1.2	-0.3	3.3	0.0	1.1
Noisy workplace	0.8	1.0	2.6	-0.9	-0.6	-0.3	-0.5	-0.6	-1.0	-1.0	-1.4	-0.7	-1.6	-1.6	-1.0	-0.7	0.4	-1.6	-0.2
Qualifications: A levels/AS levels or equivalent	0.8	1.7	7.1	-1.2	-0.4	-0.0	-1.2	-1.1	-0.6	0.2	-0.8	-1.1	-2.1	-2.0	-1.4	-1.2	1.2	-2.7	-0.5
Mouth/teeth dental problems: Dentures	0.8	1.4	3.5	0.9	0.2	0.8	1.2	0.9	0.5	-0.2	1.5	1.5	1.9	1.7	1.7	0.9	-0.4	1.8	-0.1
Arm fat mass (right)	0.8	3.4	11.8	2.2	-1.4	0.6	1.7	1.8	1.1	0.1	3.4	0.4	2.3	2.2	0.4	1.9	1.0	3.0	2.2
Ever highly irritable/argumentative for 2 days	0.8	0.9	3.4	0.5	-0.1	-0.2	0.4	0.2	-0.1	-0.1	0.0	-1.9	-0.8	-1.3	-1.8	0.3	1.2	-0.8	1.8
Medication for cholesterol, blood pressure or diabetes	0.8	1.3	6.7	0.5	2.6	0.3	0.5	0.8	1.1	1.1	-0.0	1.8	0.9	1.1	1.7	0.7	-1.3	0.3	-0.6
Exposure to tobacco smoke outside home	0.8	1.1	5.7	-0.6	-2.4	-0.5	-0.8	-1.0	-0.5	0.2	-0.1	-1.9	-0.6	-0.4	-1.8	-0.9	0.8	-0.1	0.3
Family relationship satisfaction	0.8	0.9	2.1	-1.2	-0.3	-0.9	-1.5	-1.3	-1.1	-1.0	-0.9	-0.5	-1.0	-0.9	-0.4	-1.2	0.2	-0.5	-1.3
Myopia	0.8	1.2	2.7	-1.0	0.3	-0.6	-1.1	-0.8	-1.2	-1.1	-1.6	-1.1	-1.4	-1.3	-1.0	-0.9	-0.3	-1.6	-0.4
Pain experienced in last month	0.8	1.3	4.1	-0.6	-1.4	-1.0	-0.4	-0.8	-1.2	-2.0	0.3	-1.6	-1.4	-1.2	-1.5	-0.7	0.8	-1.1	0.1
Depressed Affect (Nagel 2018)	0.7	1.4	5.0	-0.0	-1.9	-0.7	-0.3	-0.6	-0.3	0.1	0.4	-2.2	-0.7	-1.3	-2.1	-0.3	1.9	-0.7	1.6
Bipolar Disorder (2011)	0.7	0.6	2.8	0.2	0.7	-0.3	0.3	0.2	0.2	0.2	0.0	1.4	0.7	0.9	1.7	0.2	-0.9	1.3	-0.9
Mean Putamen Volume	0.7	0.9	3.7	0.7	1.9	1.2	0.9	1.0	1.0	1.0	-0.7	1.2	0.0	0.3	1.0	0.9	0.4	0.3	0.5
HDL Cholesterol	0.7	1.1	2.7	-1.0	-1.6	-1.4	-0.9	-1.2	-1.2	-0.9	-1.0	-1.1	-1.0	-0.9	-1.2	-1.1	-0.4	-0.7	-0.2
Blood Platelet Count	0.7	7.7	22.3	-1.4	-4.2	-1.5	-1.8	-2.1	-1.6	-0.8	-0.9	-4.7	-3.3	-3.3	-4.6	-1.8	3.6	-2.4	1.6
Chronotype (morning person)	0.7	1.6	5.8	1.0	2.4	2.2	1.1	1.2	1.7	1.9	-0.5	1.1	0.6	0.9	1.0	1.1	0.1	0.3	0.4
Frequency of depressed mood in last 2 weeks	0.7	1.0	4.2	0.9	-0.4	0.9	0.9	0.8	1.1	1.5	1.0	-0.0	0.6	0.3	-0.0	0.8	2.0	0.9	1.3
Ever used hormone-replacement therapy (HRT)	0.7	0.9	3.7	-0.9	-1.0	-1.0	-0.4	-1.0	-1.4	-1.9	-0.1	-1.1	-0.4	-0.9	-1.0	-1.0	0.0	-0.7	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.7	0.9	4.9	0.1	-2.2	-0.6	-0.5	-0.5	-0.3	0.1	0.5	-1.5	-0.4	-0.6	-1.4	-0.2	1.6	0.4	1.1
Serious illness, injury or assault to yourself	0.7	0.8	2.4	0.9	-0.2	0.7	0.5	0.9	0.8	0.5	1.6	0.6	1.2	1.1	0.7	0.9	0.1	1.5	0.5
Financial difficulties in last 2 years	0.7	0.9	2.5	1.0	-1.1	0.3	0.4	0.6	1.1	1.2	1.5	-0.4	0.8	0.7	-0.4	0.8	0.6	1.3	1.6
Asthma	0.7	1.3	3.5	1.1	-0.7	1.1	0.6	0.9	0.9	0.6	1.8	0.5	1.6	1.5	0.9	1.0	1.5	1.9	0.7
Seen a psychiatrist for nerves, anxiety, tension or depression	0.7	1.0	3.9	1.2	-0.3	0.7	0.9	0.7	0.7	0.2	1.7	-1.0	-0.1	-0.1	-0.8	1.0	1.1	1.1	2.0
Wheeze or whistling in the chest in last year	0.7	1.3	3.7	1.1	0.4	0.3	1.2	1.1	0.3	-0.7	1.2	1.4	1.9	1.6	1.6	1.1	-0.1	1.6	0.1
Alcohol intake frequency.	0.7	1.5	4.3	-1.1	-2.1	-1.8	-1.4	-1.4	-1.2	-1.0	-0.5	-1.7	-0.9	-0.8	-1.5	-1.2	0.9	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.4	4.0	1.0	2.0	0.3	1.1	1.1	0.8	0.6	-0.1	1.8	1.1	1.4	1.6	1.1	-1.6	1.1	-0.1
Qualifications: nursing, teaching	0.7	1.0	3.0	0.3	-0.2	0.8	0.6	0.3	0.2	-0.1	1.2	-1.4	-1.3	-1.4	-1.5	0.3	1.7	-0.9	1.4
Breast cancer (self-reported)	0.7	0.8	2.2	0.8	0.7	1.0	0.9	1.1	1.0	1.5	0.2	1.0	1.0	0.8	1.1	0.9	0.8	0.4	0.2
Medication: Bendroflumethiazide	0.7	1.0	7.3	-0.3	-0.4	-1.4	-0.7	-0.2	-1.8	-2.7	-0.6	0.0	-0.2	-0.4	0.1	-0.3	-1.5	-0.4	-0.8
Heart attack/myocardial infarction (self-reported)	0.7	0.9	3.5	0.8	0.3	1.4	1.2	1.0	1.2	1.7	0.5	0.0	0.4	0.3	0.1	0.8	1.9	0.5	0.8
Heart disease (siblings)	0.7	0.9	1.8	-1.3	-0.2	-0.4	-0.5	-1.3	-1.0	-0.9	-0.9	-0.6	-1.2	-1.3	-0.7	-1.3	-0.3	-1.2	-0.8
Leg fat mass (left)	0.7	2.8	9.5	2.0	-1.4	0.9	1.4	1.6	0.6	-0.3	3.1	0.5	2.1	2.0	0.5	1.7	0.9	2.8	1.7
Depression (Nagel 2018)	0.6	1.0	3.6	0.9	-1.2	0.3	0.7	0.5	0.9	1.6	0.7	-0.9	0.3	0.0	-0.8	0.6	1.9	0.6	1.5
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	4.5	-0.7	-0.1	-0.7	-0.5	-0.6	-0.6	-0.9	-0.5	0.7	0.5	0.4	0.7	-0.7	-2.1	0.0	-1.2
Hearing difficulty/problems with background noise	0.6	1.0	3.5	-0.3	-0.8	-0.0	-0.7	-0.5	0.1	0.8	-0.4	-1.4	-1.6	-1.4	-1.6	-0.4	1.9	-0.7	0.8
Forced vital capacity (FVC)	0.6	2.2	8.2	0.3	1.9	1.1	0.3	0.7	0.8	0.9	-0.2	2.6	1.5	1.6	2.4	0.6	-2.9	0.8	-1.3
Mouth/teeth dental problems	0.6	0.8	1.3	-1.0	-0.8	-0.8	-1.1	-1.1	-0.9	-0.5	-0.9	-1.0	-1.1	-0.9	-1.0	-1.1	-0.2	-1.1	-0.5
Arm fat percentage (right)	0.6	2.3	7.0	1.6	-2.6	0.0	1.1	1.0	0.5	-0.2	2.6	-1.1	1.1	1.0	-1.1	1.2	1.5	2.0	2.5
Hip circumference	0.6	2.7	11.0	1.8	-2.0	0.2	1.3	1.2	0.4	-0.6	3.3	0.2	2.0	1.8	0.2	1.4	1.2	2.6	1.7
Number of live births	0.6	0.9	1.8	1.1	1.3	0.5	1.4	1.0	0.6	-0.0	0.6	0.9	1.2	1.2	0.9	1.1	-0.4	0.9	0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.9	4.7	0.7	2.0	1.5	0.6	1.1	1.3	1.7	0.5	2.2	1.1	1.4	1.9	0.9	-2.0	0.6	-0.8
Tense / ‘highly strung’	0.6	0.9	3.3	0.8	1.1	1.1	0.9	0.8	1.2	1.6	0.3	0.8	0.6	0.5	0.8	0.8	1.8	0.6	0.6
Peak expiratory flow (PEF)	0.6	1.3	3.8	0.6	1.6	1.3	0.2	0.9	0.9	0.9	0.4	2.0	1.3	1.1	1.8	0.8	-1.6	0.4	-0.6
High blood pressure (siblings)	0.6	0.8	4.0	0.7	-0.5	-0.7	-0.4	0.6	-0.5	-1.0	-0.4	-1.2	-0.7	-0.7	-1.3	0.6	2.0	-0.0	1.4
Medication: Ibuprofen	0.6	0.7	1.6	-1.0	-0.9	-1.0	-0.4	-0.7	-0.9	-0.9	-0.6	-0.4	-1.3	-1.2	-0.6	-0.8	0.0	-1.2	-0.7
Whole body fat mass	0.6	2.6	8.1	2.0	-1.6	0.4	1.4	1.5	0.6	-0.5	2.9	0.1	1.9	1.8	0.1	1.7	1.0	2.7	2.0
Leg fat mass (right)	0.6	2.3	8.8	1.8	-1.6	0.7	1.2	1.4	0.4	-0.5	3.0	0.0	1.6	1.5	0.0	1.5	1.2	2.5	1.8
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	2.5	-0.1	-0.9	-0.1	0.0	-0.4	0.0	0.4	-0.3	-1.4	-1.3	-1.0	-1.6	-0.3	0.9	-0.7	1.2
Illnesses of siblings: Diabetes	0.6	0.8	1.9	-0.6	-1.4	-1.4	-0.8	-0.9	-1.3	-1.2	-0.5	-0.9	-0.8	-0.9	-0.8	-0.7	0.0	-0.2	-0.2
Arm fat percentage (left)	0.6	2.4	7.5	1.7	-2.4	0.2	1.1	1.1	0.6	-0.1	2.7	-0.8	1.3	1.1	-0.8	1.3	1.6	2.1	2.4
Mood swings	0.6	1.2	3.2	-0.6	-1.4	-1.1	-0.8	-1.0	-0.5	-0.0	-0.0	-1.8	-0.9	-1.4	-1.6	-0.8	1.4	-1.3	0.7
Medication for cholesterol	0.6	0.9	2.2	0.8	1.5	0.7	0.6	0.9	1.2	1.0	0.3	1.3	0.9	1.1	1.4	1.0	-0.6	0.5	-0.2
Medication: Gliclazide	0.6	0.7	3.0	0.3	-0.3	-0.6	-0.3	0.3	-0.9	-1.4	0.6	0.7	1.1	1.1	0.9	0.2	-1.7	0.7	-0.7
Unable to work because of sickness or disability	0.6	0.8	5.1	-0.7	-2.3	-1.0	-1.0	-1.0	-0.9	-0.2	-0.7	-0.9	-0.4	-0.3	-0.8	-0.9	0.6	0.3	-0.3
Alzheimer’s Disease (in mother)	0.5	0.6	1.7	-0.6	0.4	-0.6	-0.5	-0.6	-0.8	-1.2	-1.3	-0.6	-0.9	-1.0	-0.7	-0.6	0.2	-1.1	-0.0
Crohns Disease (2017)	0.5	1.0	3.1	1.0	-0.4	0.5	1.2	0.8	0.8	0.6	1.2	0.1	1.8	1.5	0.2	0.9	0.8	1.5	1.2
Blood White Count	0.5	3.6	8.0	-2.4	-1.6	-2.5	-2.2	-2.1	-2.4	-2.3	-2.1	0.0	-1.1	-1.0	0.1	-2.2	-1.8	-1.1	-2.8
Heel T-Score	0.5	4.0	14.5	1.8	2.0	2.6	2.0	2.2	3.1	3.8	1.5	1.1	1.4	1.4	1.0	2.0	0.3	1.0	1.6
Tanning	0.5	6.7	10.3	2.8	1.6	2.8	3.1	2.9	2.8	2.4	2.0	2.6	3.2	3.2	2.4	2.9	-0.7	3.0	1.6
Pack years adult smoking proportion	0.5	0.7	2.8	-0.6	-1.7	-0.7	-0.5	-0.9	-0.3	-0.1	0.6	-1.4	-0.7	-0.6	-1.4	-0.8	0.8	-0.4	0.6
Trunk fat mass	0.5	2.2	6.8	1.8	-1.6	0.2	1.3	1.3	0.5	-0.6	2.6	-0.1	1.7	1.5	0.0	1.5	1.0	2.3	1.9
Waist circumference	0.5	1.9	6.9	1.4	-2.0	0.1	1.0	1.0	0.3	-0.4	2.6	0.3	1.8	1.7	0.2	1.1	0.9	2.4	1.3
Medication: Ramipril	0.5	0.7	1.1	-0.6	-1.0	-0.7	-0.9	-0.8	-1.0	-0.9	-0.3	-1.0	-0.6	-0.9	-1.1	-0.8	0.9	-0.9	-0.2
Illnesses of siblings	0.5	0.6	2.0	-0.1	0.7	0.7	0.1	0.1	0.4	0.6	0.5	1.3	0.9	1.0	1.4	0.1	-1.4	0.2	-1.0
Pulse wave peak to peak time	0.5	0.6	1.6	-0.5	-0.1	-1.3	-1.1	-0.8	-0.9	-1.0	-0.6	-0.7	-0.6	-0.6	-0.5	-0.6	-0.3	-0.8	-0.4
Mouth/teeth dental problems: Loose teeth	0.5	0.6	1.8	-0.9	-0.1	-0.2	-0.4	-0.8	-0.5	0.0	-1.0	-0.7	-1.2	-1.2	-0.7	-0.9	0.1	-1.3	-0.6
Neck or shoulder pain in last month	0.5	0.7	2.5	0.6	0.3	1.1	0.3	0.8	0.9	1.6	-0.4	0.5	0.9	1.0	0.5	0.8	0.0	1.2	0.5
Commuting to job workplace: Car/motor vehicle	0.5	0.6	1.9	-0.8	-0.1	-0.5	-0.4	-0.8	-1.2	-1.3	0.1	-0.7	-0.7	-1.0	-0.6	-0.8	-0.4	-1.4	-0.4
Smoking status: Current	0.5	0.8	2.8	0.3	1.3	0.3	0.9	0.5	0.6	0.3	0.2	1.4	1.0	1.0	1.4	0.4	-1.7	0.8	-0.6
Medication: Lisinopril	0.5	0.6	2.6	0.6	-1.5	-0.4	0.0	-0.0	0.4	0.4	0.6	-0.8	0.3	-0.0	-0.7	0.3	1.6	0.8	1.3
Risk taking	0.5	0.7	1.8	-0.9	-1.0	0.0	-0.7	-0.8	-0.5	-0.1	0.1	-0.9	-1.4	-1.3	-0.9	-0.8	1.0	-1.1	-0.4
Ever depressed for a whole week	0.5	0.6	2.1	-0.6	-1.4	-0.9	-0.7	-1.1	-0.4	0.1	0.2	-1.4	-0.3	-0.6	-1.3	-0.8	0.3	0.1	0.4
Basal cell carcinoma (self-reported)	0.5	0.6	3.2	-0.1	-0.5	-0.5	-0.2	-0.3	-0.7	-1.0	0.4	-1.3	-0.6	-0.8	-1.1	-0.2	1.8	-0.7	0.7
Neuroticism (Nagel 2018)	0.4	0.9	3.5	0.2	-1.0	-0.8	-0.1	-0.3	-0.1	0.1	0.0	-1.8	-0.6	-1.1	-1.6	-0.1	1.9	-0.8	1.3
Schizophrenia (2018)	0.4	0.8	2.0	0.0	-1.1	-1.1	-0.0	-0.3	-0.8	-0.9	0.4	-1.4	-0.9	-0.9	-1.3	-0.1	1.4	-0.5	0.9
Severe depression (siblings)	0.4	0.5	1.3	-0.4	-1.0	-1.1	-1.0	-0.6	-0.6	0.2	-0.9	-0.6	-0.2	-0.5	-0.8	-0.6	-0.5	-0.7	0.1
Trunk fat percentage	0.4	1.5	6.2	1.1	-2.5	-0.7	0.5	0.5	-0.2	-0.9	1.7	-1.3	0.6	0.4	-1.1	0.8	1.3	1.3	1.9
Average weekly fortified wine intake	0.4	0.5	1.3	-0.8	-1.1	-0.9	-0.7	-1.1	-0.5	0.2	-0.8	0.2	-0.0	-0.1	0.2	-0.9	-0.4	0.0	-1.0
Fed-up feelings	0.4	0.7	2.8	0.8	-0.4	0.1	0.6	0.3	0.8	0.9	1.3	-0.5	0.3	-0.0	-0.6	0.7	1.7	0.7	1.6
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	3.3	0.9	0.2	1.8	0.8	1.0	1.3	1.8	0.9	-0.4	0.3	0.1	-0.4	0.9	0.5	-0.2	1.3
Past tobacco smoking	0.4	0.7	2.0	0.7	1.2	1.1	0.8	0.8	1.2	1.4	-0.2	0.0	-0.4	-0.3	0.0	0.8	1.3	0.2	1.1
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.7	5.6	0.8	-0.2	-0.2	0.2	0.6	0.2	0.1	0.5	-0.3	0.7	0.5	-0.2	0.7	2.4	1.0	1.2
Qualifications: None of the above	0.4	0.9	2.8	0.7	0.1	-0.1	0.9	0.8	0.1	-0.5	-0.0	1.2	1.7	1.5	1.4	0.7	-1.2	1.5	-0.3
Medication: Simvastatin	0.4	0.5	3.5	-0.7	-1.9	-0.8	-0.1	-0.7	-0.7	-0.6	0.5	-0.7	-0.3	-0.5	-0.6	-0.7	0.5	-0.1	-0.2
Father’s age at death	0.4	0.5	2.3	0.8	-0.9	0.9	0.2	0.8	0.1	0.6	0.4	-0.5	0.3	0.1	-0.4	0.8	1.5	0.4	1.0
Prospective memory result	0.4	0.5	1.2	0.9	0.1	1.1	0.5	0.9	0.7	1.0	-0.5	0.1	0.4	0.6	0.0	0.9	0.5	0.4	1.0
Loud music exposure frequency	0.4	0.4	3.8	-0.4	0.0	0.1	-0.3	-0.1	0.0	0.2	-0.4	0.8	0.2	0.5	0.7	-0.2	-1.9	0.1	-1.0
Mouth/teeth dental problems: Bleeding gums	0.4	0.5	1.7	-0.6	-0.1	-0.9	-0.3	-0.6	-0.5	-0.4	-0.6	-0.9	-1.0	-1.3	-0.9	-0.6	0.4	-1.2	0.0
Body fat percentage	0.4	1.5	6.4	1.1	-2.5	-0.4	0.6	0.6	-0.3	-1.1	1.9	-1.2	0.7	0.5	-1.1	0.8	1.3	1.5	1.9
Number of children fathered	0.4	0.4	1.8	0.3	1.3	0.5	0.4	0.4	0.6	0.9	-0.1	0.9	0.6	0.5	0.9	0.4	-0.6	0.4	-0.2
Age at first live birth	0.4	0.7	2.0	0.9	1.4	1.0	1.1	1.1	1.0	1.0	0.1	0.8	0.7	0.3	0.6	1.0	-0.4	-0.5	0.6
Angina (self-reported)	0.4	0.5	1.0	-0.7	-0.8	-0.5	-0.6	-0.7	-0.6	-0.2	-0.7	-0.7	-0.8	-1.0	-0.7	-0.7	0.8	-0.9	-0.2
Age at last live birth	0.4	0.6	2.4	0.8	1.6	0.4	1.2	0.9	0.9	0.8	0.1	0.9	0.7	0.4	0.8	0.9	-0.1	-0.4	0.5
Illness, injury, bereavement, stress in last 2 years	0.4	0.5	1.6	-0.8	1.1	-0.4	-0.5	-0.4	-0.7	-0.6	-1.3	0.2	-0.5	-0.6	0.2	-0.6	0.1	-1.3	-0.9
Average weekly red wine intake	0.4	0.6	1.3	-0.5	-0.5	-0.4	-0.8	-0.8	-0.2	0.4	0.1	-1.0	-1.1	-1.1	-1.1	-0.6	0.7	-1.0	0.5
Commuting to job workplace: Walk	0.4	0.4	2.3	0.6	-0.4	0.6	0.1	0.6	0.6	0.7	-0.3	-0.6	-0.4	-0.3	-0.6	0.6	1.5	-0.1	1.1
Eye problems/disorders: Cataract	0.4	0.4	0.8	0.8	-0.1	0.9	0.5	0.6	0.7	0.7	0.7	0.3	0.8	0.8	0.4	0.7	-0.2	0.9	0.7
Guilty feelings	0.4	0.7	2.2	1.1	-0.1	0.5	0.1	0.7	0.5	0.2	1.4	-0.4	0.5	0.3	-0.4	0.9	1.4	1.0	1.5
High cholesterol (Self-reported)	0.4	0.8	2.1	-0.9	-1.5	-0.1	-0.3	-0.9	-0.6	-0.5	0.7	-1.1	-1.1	-1.0	-1.2	-0.9	1.3	-0.3	0.0
Vascular/heart problems diagnosed by doctor	0.4	1.0	4.0	-1.0	1.7	-0.3	-0.4	-0.7	0.3	0.5	-1.1	0.8	-0.7	-0.3	0.7	-0.8	-2.0	-1.1	-1.6
Pack years of smoking	0.4	0.6	3.4	-0.5	-1.8	-0.7	-0.4	-0.7	-0.4	-0.1	0.7	-1.2	-0.4	-0.3	-1.3	-0.7	0.7	-0.0	0.6
Bipolar Disorder or Schizophrenia	0.3	0.8	2.1	0.0	-1.3	-1.4	-0.2	-0.3	-1.0	-1.4	0.1	-1.2	-0.7	-0.8	-1.1	-0.1	1.0	-0.4	0.8
Alzheimer’s Disease (in father)	0.3	0.3	0.9	-0.7	-0.5	-1.0	-0.6	-0.9	-0.6	-0.4	-0.3	0.1	0.2	0.1	-0.0	-0.8	-0.8	-0.2	-0.7
Irritable Bowel Disease (IBD)	0.3	0.7	1.8	1.0	-0.6	0.4	0.9	0.9	0.5	0.5	1.2	0.1	1.3	1.1	0.1	0.8	0.5	1.1	1.1
Age at First Birth	0.3	0.4	2.2	0.0	-0.4	-0.5	-0.3	-0.0	-0.0	0.1	0.0	-0.8	-0.5	-0.9	-0.8	0.0	1.5	-0.6	0.6
Triglycerides	0.3	0.5	1.3	-0.8	1.0	-0.5	-0.3	-0.7	-0.7	-1.1	0.2	0.2	-0.3	-0.5	0.2	-0.7	-1.0	-0.7	-1.1
Cardiovascular Disease	0.3	1.1	4.4	0.6	-2.0	-0.1	-0.1	0.3	-0.6	-0.7	1.4	-1.3	-0.0	-0.3	-1.3	0.3	2.1	0.7	1.5
Supplements: Zinc	0.3	0.3	1.4	0.4	-1.2	-0.2	0.5	0.0	-0.1	-0.6	0.7	-0.7	-0.3	-0.1	-0.8	0.2	0.5	-0.1	0.9
Diabetes (mother)	0.3	0.4	0.8	-0.4	-0.4	-0.5	-0.4	-0.4	-0.8	-0.9	-0.7	-0.8	-0.8	-0.8	-0.9	-0.4	-0.4	-0.7	-0.0
Age when periods started (menarche)	0.3	0.8	2.1	-0.7	-0.4	-0.8	-0.9	-0.7	-0.7	-0.6	-0.3	-1.3	-1.1	-1.5	-0.9	-0.7	0.6	-1.4	-0.3
Qualifications: CSEs or equivalent	0.3	0.4	1.0	0.1	0.6	-0.5	-0.1	0.2	0.0	-0.1	-0.5	-1.0	-1.0	-0.7	-1.0	0.1	-0.1	-0.8	0.9
High blood pressure	0.3	0.9	4.5	0.6	-2.1	-0.4	-0.2	0.2	-0.7	-0.9	0.7	-0.8	0.6	0.3	-0.7	0.3	1.6	1.1	1.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.4	1.2	0.4	-0.1	0.1	1.1	0.3	0.2	-0.2	0.9	0.6	1.1	0.4	0.7	0.3	0.8	0.7	0.3
Number of incorrect matches in round	0.3	0.5	2.0	-0.7	0.9	-0.5	-0.3	-0.3	-0.7	-0.4	-1.2	0.6	-0.1	0.0	0.6	-0.5	-1.1	-0.7	-1.4
Alcohol usually taken with meals	0.3	0.4	2.0	-0.1	-0.4	0.1	0.4	-0.2	-0.2	-0.1	0.1	-0.8	-1.0	-1.0	-0.8	-0.1	1.4	-0.7	0.7
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.1	-0.1	-0.8	-0.2	-0.6	-0.6	-0.4	-0.8	0.3	-1.0	-0.1	-0.7	-0.8	-0.3	0.0	-0.2	0.7
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	1.4	0.5	-0.1	1.2	0.7	0.3	0.6	0.5	0.5	-0.2	-0.4	-0.2	-0.2	0.5	1.0	0.3	0.9
Medication: Lansoprazole	0.3	0.3	1.8	-0.0	-0.5	-0.5	0.1	-0.4	-0.1	0.1	0.5	-1.0	0.1	-0.3	-0.8	-0.3	1.4	-0.0	0.5
Pulse wave Arterial Stiffness index	0.3	0.4	1.2	0.3	0.3	1.1	1.0	0.7	0.7	0.7	0.4	0.8	0.5	0.5	0.6	0.5	0.1	0.6	0.2
Qualifications: O levels/GCSEs or equivalent	0.3	0.4	1.0	0.2	0.3	1.0	-0.1	0.2	0.7	0.8	0.8	-0.5	-0.8	-0.6	-0.6	0.2	0.8	-0.8	0.7
Glaucoma (self-reported)	0.3	0.3	0.9	0.2	0.2	0.6	0.3	0.2	0.1	-0.3	0.4	0.8	0.9	0.7	0.9	0.2	-0.7	0.8	-0.2
Leg fat percentage (right)	0.3	1.2	5.1	0.7	-2.3	-0.0	0.4	0.3	-0.6	-1.3	1.9	-1.0	0.4	0.3	-1.0	0.4	1.5	1.2	1.3
Medication for pain relief, constipation, heartburn	0.3	0.5	1.6	-0.3	-0.3	0.1	-1.0	-0.6	0.4	0.9	0.4	-1.3	-1.0	-0.7	-1.2	-0.4	0.5	-0.9	0.3
Mean time to correctly identify matches	0.3	0.7	2.9	-0.9	0.5	-0.3	-0.7	-0.5	-1.0	-1.0	-1.7	0.4	-0.7	-0.3	0.4	-0.7	-0.2	-0.5	-1.5
Comparative height size at age 10	0.3	1.6	5.2	-1.1	-0.6	-1.5	-1.3	-1.1	-1.6	-2.3	-0.7	0.9	0.0	0.1	0.9	-1.1	-1.9	0.0	-2.2
Leg pain on walking	0.3	0.3	1.1	0.6	0.4	0.6	0.8	0.6	0.3	0.2	0.2	0.6	0.8	0.7	0.6	0.6	0.1	1.0	0.3
Medication: Aspirin	0.3	0.4	1.7	-0.4	-0.5	-0.6	-0.1	-0.3	-1.0	-1.3	-0.8	0.1	0.3	0.1	0.2	-0.4	-0.6	0.4	-0.7
Hypertension (Self-reported)	0.3	0.7	4.7	0.5	-2.2	-0.6	-0.3	0.2	-0.8	-0.9	0.5	-0.7	0.6	0.4	-0.6	0.3	1.2	1.1	0.9
Smoking status: Previous	0.3	0.5	2.4	-0.4	-1.5	-0.6	-0.7	-0.6	-0.9	-1.1	0.7	-0.3	0.4	0.3	-0.4	-0.5	-0.7	-0.0	-0.5
Long-standing illness, disability or infirmity	0.3	0.5	3.3	0.5	-0.4	0.4	0.6	0.4	-0.3	-0.9	0.6	-0.6	-0.0	-0.1	-0.6	0.4	1.8	0.4	1.0
Friendships satisfaction	0.3	0.3	1.3	-0.7	-0.4	-0.2	-1.0	-0.9	-0.4	-0.0	-0.3	0.3	0.1	-0.0	0.2	-0.8	-1.1	-0.1	-0.9
Back pain experienced in last month	0.3	0.5	1.1	0.8	0.5	0.7	0.2	1.0	0.6	1.0	-0.9	0.5	0.6	0.6	0.3	0.9	0.4	0.7	0.6
Medication: Aspirin	0.3	0.4	1.9	-0.4	-1.1	-0.6	-0.3	-0.5	-1.0	-1.4	-0.4	-0.5	-0.0	-0.2	-0.4	-0.5	-0.1	0.4	-0.2
Number of self-reported non-cancer illnesses	0.3	0.6	2.6	0.4	-1.6	0.4	0.0	0.0	-0.0	-0.2	0.9	-0.3	0.6	0.4	-0.2	0.2	1.5	1.4	0.8
Mother’s age at death	0.3	0.4	2.3	0.0	-1.5	0.1	-0.2	-0.2	-0.7	-0.8	0.5	-0.9	-0.4	-0.4	-0.9	-0.1	0.8	0.1	0.6
Illnesses of father: High blood pressure	0.3	0.3	1.1	-0.4	0.1	-0.5	-0.4	-0.5	0.2	1.0	-1.1	0.3	0.3	0.2	0.6	-0.4	-0.8	-0.1	-0.8
Ever smoked	0.3	0.5	2.7	-0.3	-0.2	-1.1	-0.1	-0.2	-0.9	-1.6	0.2	0.2	0.4	0.2	0.3	-0.3	-1.2	-0.2	-0.9
Leg fat percentage (left)	0.3	1.1	4.2	0.9	-1.9	0.3	0.5	0.6	-0.3	-0.9	2.0	-0.2	1.1	0.9	-0.3	0.7	0.7	1.7	1.1
Commuting to job workplace: Cycle	0.3	0.3	1.3	0.2	0.5	0.8	0.6	0.3	0.6	1.1	-0.6	-0.2	-0.6	-0.5	-0.3	0.2	-0.3	-1.1	0.4
Reaction Time	0.2	0.3	1.7	-0.7	0.3	0.1	-0.8	-0.6	-0.5	-0.1	-1.3	-0.1	-0.7	-0.3	-0.0	-0.6	0.2	-0.3	-0.8
Crohns Disease (2012)	0.2	0.3	1.3	0.3	0.2	0.1	0.8	0.2	-0.0	-0.3	-0.7	0.6	1.1	1.0	0.7	0.2	-0.2	0.8	0.0
HbA1C	0.2	0.2	1.0	0.3	-1.0	-0.4	0.0	-0.1	0.0	-0.2	0.5	0.3	0.5	0.1	-0.2	0.1	0.4	0.6	0.7
Lupus	0.2	0.3	1.1	0.4	0.2	0.9	0.8	0.5	0.3	0.4	1.1	-0.2	-0.1	0.1	-0.2	0.5	-0.2	0.3	0.4
Schizophrenia (2014)	0.2	0.5	1.2	0.1	-0.9	-0.9	0.2	0.0	-0.7	-1.1	0.7	-1.0	-0.7	-0.7	-1.0	0.1	1.0	-0.5	0.7
Ulcerative Colitis	0.2	0.3	0.7	0.7	-0.7	0.7	0.5	0.8	-0.1	-0.3	0.6	-0.0	0.5	0.3	0.1	0.7	-0.1	0.5	0.7
Systolic Blood Pressure	0.2	1.0	2.3	-1.1	-1.1	-0.9	-1.4	-1.2	-1.0	0.0	-1.5	-0.8	-0.9	-0.9	-1.1	-1.2	-0.5	-0.6	-0.5
Smoking Status	0.2	0.6	2.9	-0.6	-0.5	-0.5	-0.3	-0.5	-0.8	-1.1	-0.5	0.5	0.3	0.3	0.5	-0.6	-1.7	-0.2	-1.2
Neuroticism	0.2	0.5	1.8	-0.3	-0.8	-0.2	-0.3	-0.8	0.3	0.5	0.7	-1.0	-0.4	-0.6	-0.9	-0.4	1.4	-0.5	0.5
Angina	0.2	0.3	0.7	-0.7	-0.5	-0.5	-0.5	-0.6	-0.5	0.0	-0.7	-0.4	-0.7	-0.8	-0.4	-0.7	0.4	-0.8	-0.3
Current tobacco smoking	0.2	0.4	2.0	-0.0	0.9	-0.1	0.7	0.2	0.2	-0.1	-0.0	0.9	0.7	0.6	1.0	0.1	-1.4	0.4	-0.6
Hayfever, allergic rhinitis or eczema	0.2	0.4	0.7	0.7	0.6	-0.5	0.5	0.9	0.6	0.4	-0.8	0.6	0.3	0.6	0.7	0.8	0.4	0.6	0.4
Multivitamins +/- minerals	0.2	0.3	0.8	0.2	0.6	0.9	0.5	0.5	0.1	-0.2	0.4	0.9	0.4	0.7	0.7	0.4	-0.4	0.4	-0.4
Stomach or abdominal pain in last month	0.2	0.3	0.9	-0.7	0.5	-0.7	-0.0	-0.5	0.1	1.0	0.4	0.1	-0.6	-0.4	0.0	-0.7	0.1	-0.7	-0.7
Fluid intelligence score	0.2	0.3	2.4	-0.1	0.4	-0.1	-0.3	-0.3	0.3	0.1	0.7	-0.8	-0.5	-0.7	-0.6	-0.2	1.6	-0.4	0.5
Neuroticism score	0.2	0.4	0.9	-0.5	-0.4	-0.4	-0.8	-0.8	-0.0	0.2	0.4	-0.9	-0.6	-0.9	-0.9	-0.6	0.7	-0.9	0.3
Time employed in main current job	0.2	0.2	1.5	0.0	-0.1	-0.5	0.1	-0.1	-0.4	-0.3	0.2	-0.3	0.1	-0.5	-0.3	-0.1	1.2	-0.6	0.3
Alcohol intake versus 10 years previously	0.2	0.3	1.5	-0.0	-0.7	-1.1	-0.5	-0.1	-0.8	-1.2	-0.6	-0.6	-0.0	-0.2	-0.5	-0.1	0.4	0.1	0.0
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	2.6	-0.0	1.4	0.9	-0.1	0.3	0.7	1.2	-0.5	1.4	0.2	0.4	1.2	0.2	-1.6	-0.4	-0.8
Medication: Cholesterol lowering	0.2	0.3	1.8	-0.0	-1.4	-0.3	0.1	-0.2	-0.4	-0.5	0.3	-0.9	-0.1	-0.3	-0.9	-0.2	0.8	-0.1	0.6
Depression (self-reported)	0.2	0.3	0.8	-0.2	0.5	0.3	-0.1	-0.1	0.0	-0.0	-0.5	0.8	0.3	0.5	0.9	-0.1	-0.9	0.6	-0.8
Breastfed as a baby	0.2	0.2	1.2	0.2	-0.1	0.4	-0.5	0.1	0.4	1.1	0.3	-0.4	-0.1	0.0	-0.5	0.1	1.0	-0.4	0.7
Seen doctor (GP) for nerves, anxiety, tension or depression	0.2	0.3	1.6	0.6	-0.4	0.1	0.5	0.2	0.3	-0.4	0.6	-0.0	0.6	0.4	0.0	0.4	0.8	1.3	1.0
Blood clot in the leg (DVT)	0.2	0.2	1.3	-0.0	0.0	-0.2	-0.1	-0.2	-0.1	0.0	-0.3	-0.7	-1.1	-0.8	-0.7	-0.1	-0.4	-0.3	0.5
Headache pain in last month	0.2	0.3	3.4	-0.0	-0.1	0.3	-0.1	-0.1	0.7	1.9	-0.9	0.0	0.1	0.0	0.1	-0.0	0.2	0.1	0.2
Qualifications: College or University degree	0.2	0.5	2.3	-0.6	-0.5	0.7	-0.8	-0.6	-0.3	0.6	-0.3	-0.2	-0.7	-0.9	-0.2	-0.6	1.5	-0.9	-0.7
Emphysema/chronic bronchitis	0.2	0.2	2.4	0.2	-0.4	0.2	0.4	0.2	-0.6	-1.5	-0.4	-0.0	0.2	0.1	0.1	0.2	-0.3	0.1	-0.0
Medication: Omeprazole	0.2	0.3	1.2	0.1	-0.8	-0.1	0.1	-0.1	0.2	0.3	0.5	-1.1	-0.3	-0.3	-0.8	-0.1	0.5	0.1	0.9
Number of full sisters	0.2	0.2	1.1	-0.3	-0.3	0.3	0.1	-0.3	-0.0	0.2	-0.3	-0.8	-1.0	-0.6	-0.8	-0.3	-0.4	-0.3	0.1
Overall health rating	0.2	0.5	1.8	0.2	-1.2	-0.9	0.1	-0.0	-0.8	-1.3	0.2	-1.0	0.1	-0.2	-0.9	0.1	0.6	0.6	1.0
Had major operations	0.2	0.2	0.5	0.7	-0.3	0.5	0.4	0.7	0.4	0.1	0.5	0.1	0.3	0.1	0.1	0.7	0.4	0.6	0.6
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.7	0.3	0.1	0.0	0.5	0.5	0.1	-0.3	0.3	-0.5	-0.8	-0.3	-0.5	0.4	0.8	-0.0	0.4
Osteoarthritis (self-reported)	0.2	0.3	1.0	-0.3	-0.8	-0.7	-0.2	-0.3	-0.9	-1.0	0.2	0.4	0.5	0.4	0.6	-0.4	-0.2	0.3	-0.7
Ever taken oral contraceptive pill	0.2	0.3	1.1	0.6	0.4	0.4	0.6	0.2	0.1	0.2	0.4	-0.4	0.2	0.2	-0.5	0.4	0.8	0.5	1.1
Hearing aid user	0.2	0.2	2.0	-0.1	0.1	-0.0	0.1	-0.1	-0.7	-1.4	-0.3	-0.5	-0.3	-0.2	-0.4	-0.1	0.6	0.3	0.0
Eye problems/disorders: Glaucoma	0.2	0.2	0.8	-0.4	-0.7	-0.2	-0.3	-0.4	-0.5	-0.9	0.2	0.3	0.5	0.3	0.3	-0.4	-0.6	0.5	-0.4
Medication: Atorvastatin	0.2	0.2	0.6	0.2	0.5	0.3	0.1	0.1	0.4	0.3	-0.2	-0.5	-0.8	-0.6	-0.5	0.1	0.1	-0.6	0.8
Alcohol drinker status: Never	0.2	0.2	1.4	-0.4	-1.2	-0.1	-0.3	-0.6	-0.3	-0.0	0.0	-0.1	-0.1	0.0	-0.0	-0.5	0.8	0.7	-0.2
Diastolic blood pressure, automated reading	0.2	0.8	2.7	0.5	-1.6	-0.5	-0.2	0.2	-0.4	-0.6	0.6	-1.4	0.1	0.1	-1.4	0.2	1.3	0.7	1.4
Cholesterol lowering medication	0.2	0.3	0.9	-0.3	-0.3	-0.3	0.1	-0.1	-0.7	-1.0	-0.1	-0.6	-0.8	-0.9	-0.5	-0.2	0.8	-0.3	0.4
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	1.2	-0.1	-0.8	-0.4	-0.0	-0.1	-0.3	-0.2	0.2	-1.1	-0.6	-0.6	-0.9	-0.2	0.4	-0.3	0.6
Deep venous thrombosis (DVT) (self-reported)	0.2	0.2	1.0	0.1	0.0	0.1	0.1	-0.1	0.1	0.2	-0.2	-0.7	-1.0	-0.6	-0.8	0.0	-0.3	-0.1	0.7
Bipolar Disorder (2018)	0.1	0.2	1.1	-0.0	-0.7	-1.0	-0.3	-0.1	-0.6	-1.0	-0.4	-0.2	-0.1	-0.2	-0.1	-0.0	-0.1	0.0	0.1
Intelligence (Savage-Jansen 2018)	0.1	0.4	0.9	-0.9	0.5	-0.1	-0.9	-1.0	-0.3	-0.3	-0.2	-0.4	-0.7	-0.9	-0.3	-0.9	0.3	-0.8	-0.6
Worry (Nagel 2018)	0.1	0.1	1.1	0.4	1.0	0.1	0.3	0.3	0.5	0.2	-0.1	0.1	0.2	0.3	0.3	0.4	-0.1	0.2	0.2
Alzheimer’s Disease (including proxy)	0.1	0.1	0.5	-0.0	0.4	-0.4	-0.1	-0.1	-0.2	-0.6	-0.3	0.2	0.4	0.3	0.1	-0.0	-0.7	-0.1	0.0
Coronary Artery Disease (CAD)	0.1	0.1	0.3	0.1	-0.2	-0.3	-0.1	0.1	-0.3	-0.3	0.6	-0.1	-0.3	-0.3	-0.5	0.1	-0.5	-0.4	0.3
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.3	-0.0	0.5	0.1	0.5	-0.2	0.4	0.3	0.6	-0.2	0.3	0.1	-0.2	0.0	0.4	-0.3	0.4
Height	0.1	1.8	4.9	-1.5	1.8	-0.7	-1.2	-1.0	-0.9	-0.6	-1.9	1.0	-1.4	-1.0	0.7	-1.1	-1.5	-1.8	-2.2
Allergy or Eczema	0.1	0.2	1.1	0.2	-0.0	-1.0	0.3	0.3	-0.2	-0.4	-1.1	-0.2	-0.3	-0.1	-0.2	0.2	0.7	-0.1	0.3
Hair Pigment	0.1	2.2	6.9	-0.6	-1.7	-0.4	0.0	-1.0	-0.8	-1.3	0.7	-2.6	-2.2	-1.9	-2.6	-0.8	1.5	-1.1	1.1
Sensitivity / hurt feelings	0.1	0.2	1.4	-0.0	-0.5	-1.2	-0.1	-0.3	-0.4	-0.8	0.7	-0.4	0.2	-0.1	-0.2	-0.1	0.1	-0.3	0.3
Other serious medical condition/disability diagnosed by doctor	0.1	0.2	0.9	-0.3	0.3	0.9	0.2	-0.2	-0.3	-0.7	0.4	0.3	0.4	0.0	0.4	-0.2	0.4	0.1	-0.5
Systolic blood pressure, automated reading	0.1	0.4	1.9	-0.6	-0.7	-0.7	-1.0	-0.5	-0.6	0.2	-1.4	0.3	0.0	0.2	0.1	-0.6	-0.8	0.3	-0.9
Vitamin and mineral supplements	0.1	0.1	0.4	0.2	-0.3	-0.4	-0.0	0.1	0.2	0.2	0.4	-0.6	-0.2	-0.3	-0.5	0.2	0.6	-0.2	0.6
Maternal smoking around birth	0.1	0.1	0.6	0.3	-0.2	0.0	0.3	0.3	0.3	0.1	0.1	-0.5	0.1	0.1	-0.6	0.2	0.0	0.0	0.7
Chronic bronchitis/emphysema (father)	0.1	0.2	0.8	0.1	-0.6	0.9	0.4	0.2	-0.1	-0.1	0.6	-0.0	-0.1	-0.1	-0.3	0.1	0.9	0.1	0.3
Nervous feelings	0.1	0.1	0.4	-0.0	0.7	0.4	-0.0	0.3	0.4	0.1	-0.3	0.5	-0.3	-0.0	0.5	0.2	-0.6	-0.1	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.2	0.8	0.2	0.0	0.9	0.5	0.4	0.3	0.6	-0.2	-0.6	-0.0	-0.4	-0.5	0.2	0.3	-0.8	0.6
Allergy	0.1	0.2	0.7	-0.5	0.2	0.4	-0.2	-0.5	-0.3	-0.1	0.2	-0.4	-0.4	-0.7	-0.6	-0.5	-0.3	-0.8	-0.2
Worrier / anxious feelings	0.1	0.1	0.3	-0.2	0.2	-0.6	-0.4	-0.5	-0.2	-0.6	0.5	-0.3	0.3	0.1	-0.0	-0.3	-0.1	0.1	-0.2
Pulse rate	0.1	0.2	1.2	-0.8	-0.5	0.1	-0.5	-0.6	-0.2	-0.3	0.4	0.3	-0.4	-0.0	0.3	-0.7	0.1	0.1	-1.1
Happiness	0.1	0.2	0.9	-0.2	0.7	0.1	0.2	-0.2	0.4	0.3	0.1	0.9	-0.0	-0.0	0.8	-0.1	0.1	-0.1	-0.4
Standing height	0.1	0.8	2.7	0.1	1.6	-0.2	-0.1	0.3	-0.1	-0.6	-0.6	1.6	0.4	0.5	1.5	0.3	-1.4	-0.1	-1.1
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.6	0.2	-0.5	0.5	0.0	0.1	0.3	0.4	-0.0	0.3	0.6	0.5	0.3	0.2	0.8	0.5	0.0
Eye problems/disorders: None of the above	0.1	0.1	0.4	-0.2	0.4	0.3	0.2	0.1	0.0	0.3	-0.6	0.1	-0.4	-0.2	0.0	-0.1	-0.4	-0.4	-0.3
Pulse rate, automated reading	0.1	0.3	1.6	0.4	-1.2	0.5	0.6	0.2	0.3	0.3	0.2	-0.3	0.4	0.2	-0.2	0.3	1.1	0.4	0.6
Supplements: Vitamin C	0.1	0.1	0.7	0.5	0.3	0.3	0.5	0.4	0.3	0.3	-0.9	0.3	0.2	0.2	0.3	0.4	-0.3	0.2	0.4
Knee pain experienced in last month	0.1	0.2	0.7	0.3	-0.1	0.2	0.3	0.3	-0.4	-0.6	-0.2	0.5	0.9	0.7	0.5	0.2	-0.5	0.8	-0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.3	0.8	0.3	0.2	0.4	0.0	0.6	0.4	0.7	-0.2	0.9	0.7	0.8	0.7	0.5	-0.0	0.3	-0.3
Commuting to job workplace: Public transport	0.1	0.2	0.7	-0.3	-0.4	0.0	-0.3	-0.3	0.0	0.3	-0.9	0.4	0.2	0.3	0.4	-0.2	0.8	0.2	-0.6
Medication: Blood pressure	0.1	0.2	0.6	0.5	-0.4	-0.4	0.1	0.4	-0.5	-0.8	-0.1	-0.1	0.5	0.4	-0.0	0.3	0.2	0.8	0.5
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.6	0.4	0.3	-0.1	0.3	0.1	0.2	-0.1	0.8	-0.3	-0.1	-0.3	-0.3	0.3	0.4	-0.0	0.7
Ulcerative Colitis (UC)	0.0	0.1	0.8	0.0	-0.9	-0.1	-0.0	0.2	-0.4	-0.3	0.3	-0.1	0.1	0.0	-0.1	0.0	-0.0	-0.1	0.1
Breast Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.3	0.7	0.1	-0.7	-0.9	-0.4	0.3	0.1	0.0	-0.4	0.7	0.7	0.5	0.8	0.2	-0.4	0.2	-0.8
Ever had hysterectomy (womb removed)	0.0	0.0	0.2	-0.1	-0.2	-0.1	-0.1	-0.1	-0.2	-0.3	-0.1	-0.0	0.3	0.3	0.0	-0.1	-0.5	0.2	0.1

Hub : Genes

ZCRB1

Models

Trait associations