[Hub]/) : Traits : Impedance of arm (right) :

chr15:76,596,250-78,474,476

Best TWAS P=1.64e-15 · Best GWAS P=1.51e-14 conditioned to 0.0457

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-797A18.4 0.19 0.12 lasso 8 0.16 2.1e-13 -4.5 -6.5 6.6e-11 -0.79 0.70 0.30 FALSE
2 GTEx Adipose Visceral Omentum RP11-797A18.4 0.06 0.05 lasso 3 0.06 4.1e-04 6.9 -6.4 1.5e-10 -0.78 0.05 0.85 FALSE
3 GTEx Adrenal Gland RP11-797A18.4 0.13 0.04 enet 18 0.11 1.1e-04 -4.4 -6.3 2.3e-10 -0.75 0.04 0.80 FALSE
4 GTEx Artery Aorta RP11-797A18.4 0.13 0.11 enet 17 0.12 2.3e-07 -4.5 -6.1 1.1e-09 -0.76 0.17 0.82 FALSE
5 GTEx Artery Coronary RP11-797A18.3 0.12 0.03 lasso 10 0.01 1.1e-01 -4.4 -6.9 5.5e-12 -0.80 0.04 0.50 FALSE
6 GTEx Artery Tibial TSPAN3 0.14 0.07 lasso 5 0.10 1.6e-08 7.4 -8.0 1.6e-15 -0.82 0.02 0.98 TRUE
7 GTEx Artery Tibial RP11-797A18.4 0.14 0.03 enet 25 0.09 2.3e-07 6.9 -6.6 5.0e-11 -0.66 0.05 0.95 FALSE
8 GTEx Brain Caudate basal ganglia PSTPIP1 0.22 0.12 lasso 9 0.13 1.4e-04 7.1 6.5 9.7e-11 0.80 0.03 0.92 FALSE
9 GTEx Brain Caudate basal ganglia RP11-797A18.4 0.21 0.14 lasso 5 0.12 2.9e-04 6.9 -7.0 2.0e-12 -0.81 0.07 0.85 FALSE
10 GTEx Brain Cerebellar Hemisphere RP11-797A18.3 0.14 0.03 lasso 6 0.02 7.9e-02 -2.1 -5.3 1.0e-07 -0.66 0.06 0.33 FALSE
11 GTEx Brain Cerebellar Hemisphere RP11-797A18.4 0.14 0.12 enet 10 0.12 6.4e-04 4.5 -5.9 3.2e-09 -0.75 0.06 0.67 FALSE
12 GTEx Brain Cerebellum HMG20A 0.14 0.03 enet 7 0.10 6.4e-04 7.1 -6.6 3.3e-11 -0.73 0.04 0.72 FALSE
13 GTEx Brain Cerebellum RP11-797A18.4 0.29 0.20 lasso 9 0.25 4.0e-08 7.1 -6.1 1.1e-09 -0.78 0.06 0.91 FALSE
14 GTEx Brain Cortex RP11-797A18.4 0.47 0.28 enet 14 0.34 3.3e-10 7.0 -6.8 1.4e-11 -0.81 0.03 0.97 FALSE
15 GTEx Brain Frontal Cortex BA9 RP11-797A18.4 0.35 0.35 lasso 5 0.35 4.8e-10 6.9 -6.8 1.5e-11 -0.79 0.12 0.88 FALSE
16 GTEx Brain Hypothalamus RP11-797A18.4 0.21 0.18 lasso 7 0.22 7.6e-06 7.1 -7.6 2.7e-14 -0.92 0.01 0.98 FALSE
17 GTEx Brain Nucleus accumbens basal ganglia RP11-797A18.4 0.12 0.22 lasso 1 0.17 3.1e-05 6.9 -6.9 6.7e-12 -0.80 0.06 0.72 FALSE
18 GTEx Brain Putamen basal ganglia RP11-797A18.4 0.27 0.06 lasso 5 0.06 1.7e-02 6.9 -6.2 4.0e-10 -0.77 0.03 0.45 FALSE
19 GTEx Cells EBV-transformed lymphocytes PSTPIP1 0.13 0.04 enet 13 0.10 4.0e-04 5.6 -5.9 2.8e-09 -0.73 0.07 0.76 FALSE
20 GTEx Cells EBV-transformed lymphocytes TSPAN3 0.26 0.14 lasso 6 0.12 8.2e-05 -5.6 -6.0 2.2e-09 -0.53 0.14 0.28 FALSE
21 GTEx Cells EBV-transformed lymphocytes RP11-797A18.4 0.16 0.08 lasso 6 0.14 2.7e-05 -4.5 -6.3 2.2e-10 -0.77 0.09 0.82 FALSE
22 GTEx Cells Transformed fibroblasts TSPAN3 0.17 0.16 lasso 3 0.17 1.7e-12 7.4 -6.8 1.5e-11 -0.84 0.00 1.00 FALSE
23 GTEx Cells Transformed fibroblasts RP11-797A18.4 0.12 0.11 lasso 8 0.12 4.0e-09 7.0 -7.4 1.3e-13 -0.86 0.02 0.98 FALSE
24 GTEx Cells Transformed fibroblasts RP11-797A18.6 0.07 0.06 lasso 4 0.06 2.2e-05 7.4 -6.3 2.6e-10 -0.77 0.01 0.98 FALSE
25 GTEx Colon Transverse RP11-797A18.4 0.15 0.03 lasso 5 0.05 3.1e-03 -4.5 -6.7 3.0e-11 -0.77 0.04 0.89 FALSE
26 GTEx Esophagus Gastroesophageal Junction RP11-797A18.4 0.14 0.11 enet 10 0.15 6.0e-06 4.5 -6.5 7.1e-11 -0.81 0.02 0.97 FALSE
27 GTEx Esophagus Muscularis RP11-797A18.4 0.07 0.09 lasso 3 0.09 6.3e-06 7.4 -7.4 1.8e-13 -0.87 0.01 0.98 FALSE
28 GTEx Heart Atrial Appendage RP11-797A18.4 0.16 0.06 enet 17 0.11 1.5e-05 6.9 -6.0 2.5e-09 -0.72 0.10 0.86 FALSE
29 GTEx Heart Left Ventricle RP11-797A18.4 0.16 0.09 enet 12 0.08 3.3e-05 7.4 -7.1 1.6e-12 -0.84 0.02 0.98 FALSE
30 GTEx Lung RP11-797A18.3 0.05 0.03 enet 8 0.04 3.4e-04 -4.5 -6.4 2.0e-10 -0.79 0.08 0.82 FALSE
31 GTEx Lung RP11-797A18.4 0.19 0.09 enet 21 0.17 3.5e-13 6.9 -6.7 2.2e-11 -0.68 0.09 0.91 FALSE
32 GTEx Muscle Skeletal HMG20A 0.04 0.00 lasso 4 0.01 7.2e-02 5.6 -5.5 3.3e-08 -0.55 0.03 0.75 FALSE
33 GTEx Muscle Skeletal RP11-797A18.4 0.14 0.14 lasso 6 0.18 6.6e-17 7.0 -6.6 4.0e-11 -0.81 0.05 0.95 FALSE
34 GTEx Nerve Tibial TSPAN3 0.13 0.08 lasso 2 0.07 9.0e-06 7.4 -7.3 2.6e-13 -0.85 0.01 0.99 FALSE
35 GTEx Ovary RP11-797A18.6 0.21 0.04 enet 15 0.13 3.7e-04 7.4 -5.6 2.6e-08 -0.78 0.04 0.63 FALSE
36 GTEx Skin Not Sun Exposed Suprapubic RP11-797A18.3 0.15 0.08 lasso 3 0.09 1.2e-05 -4.5 -6.8 1.5e-11 -0.78 0.13 0.82 FALSE
37 GTEx Skin Not Sun Exposed Suprapubic RP11-797A18.4 0.19 0.10 enet 31 0.15 8.0e-09 7.0 -7.0 2.0e-12 -0.72 0.11 0.89 FALSE
38 GTEx Skin Sun Exposed Lower leg TSPAN3 0.11 0.03 enet 8 0.10 2.5e-08 -5.6 -6.2 6.1e-10 -0.68 0.08 0.85 FALSE
39 GTEx Skin Sun Exposed Lower leg RP11-797A18.4 0.16 0.08 enet 23 0.09 1.3e-07 6.9 -7.4 1.6e-13 -0.84 0.03 0.97 FALSE
40 GTEx Testis PSTPIP1 0.10 0.03 lasso 3 0.02 4.1e-02 7.0 -7.0 1.9e-12 -0.81 0.04 0.82 FALSE
41 GTEx Testis TSPAN3 0.19 0.05 lasso 7 0.06 1.6e-03 6.9 -6.1 1.1e-09 -0.72 0.04 0.86 FALSE
42 GTEx Uterus RP11-797A18.4 0.26 0.11 enet 12 0.16 4.0e-04 7.6 -5.8 6.4e-09 -0.84 0.01 0.90 FALSE
43 GTEx Whole Blood TSPAN3 0.05 0.04 lasso 2 0.03 1.8e-03 -5.6 -5.9 4.5e-09 -0.55 0.11 0.36 FALSE
44 GTEx Whole Blood RP11-797A18.4 0.21 0.18 enet 26 0.19 1.6e-17 -4.5 -5.5 5.1e-08 -0.64 1.00 0.00 FALSE
45 GTEx Whole Blood RP11-797A18.6 0.04 0.02 enet 8 0.03 4.9e-04 -4.4 -5.5 3.3e-08 -0.75 0.15 0.39 FALSE
46 NTR Blood TSPAN3 0.07 0.08 lasso 9 0.09 5.1e-27 6.9 -6.6 3.9e-11 -0.79 0.31 0.69 FALSE
47 The Cancer Genome Atlas Bladder Urothelial Carcinoma TSPAN3 0.05 0.00 enet 7 0.02 9.7e-03 6.9 -6.2 7.0e-10 -0.71 0.01 0.74 FALSE
48 The Cancer Genome Atlas Breast Invasive Carcinoma TSPAN3 0.03 0.01 blup 43 0.01 8.2e-03 3.9 -5.8 4.9e-09 -0.68 0.03 0.64 FALSE
49 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma TSPAN3 0.05 0.01 blup 43 0.01 1.5e-02 7.0 -7.3 3.5e-13 -0.78 0.01 0.48 FALSE