Hub : Genes

PSTPIP1

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0700	0.0320	9.9e-04	0.054	NA	0.025	NA	0.033	3.1e-05	NA	3.9e-03	NA	1.0e-03
2	GTEx	Brain Caudate basal ganglia	0.2160	0.0900	4.2e-04	0.124	NA	0.131	NA	0.131	2.1e-04	NA	1.4e-04	NA	1.4e-04
3	GTEx	Cells EBV-transformed lymphocytes	0.1260	0.0540	5.4e-04	0.042	NA	0.099	NA	0.089	1.7e-02	NA	4.0e-04	NA	7.8e-04
4	GTEx	Lung	0.0534	0.0292	9.1e-03	0.004	NA	0.004	NA	0.000	1.5e-01	NA	1.5e-01	NA	3.3e-01
5	GTEx	Testis	0.0970	0.0600	6.7e-03	0.026	NA	0.009	NA	0.021	2.6e-02	NA	1.3e-01	NA	4.1e-02
6	METSIM	Adipose	0.0402	0.0189	5.3e-05	0.045	0.029	0.023	0.032	0.037	2.4e-07	3.1e-05	1.7e-04	1.2e-05	2.3e-06
7	YFS	Blood	0.3806	0.0646	0.0e+00	0.053	0.110	0.120	0.112	0.109	7.0e-17	3.9e-34	5.5e-37	1.2e-34	1.1e-33
8	TCGA	Brain Lower Grade Glioma	0.0679	0.0293	2.9e-05	0.023	0.017	0.023	NA	0.024	1.0e-03	3.9e-03	1.0e-03	NA	8.9e-04
9	TCGA	Thyroid Carcinoma	0.0730	0.0340	1.9e-03	0.015	0.024	0.031	NA	0.025	1.2e-02	2.1e-03	4.8e-04	NA	1.5e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
Bipolar Disorder (2018)	0.2	0.3	0.8	0.9	-0.1	-0.8	0.7	0.2	0.4	-0.2	-0.0	-0.9
Bipolar Disorder or Schizophrenia	0.2	0.4	1.8	0.6	0.4	-1.3	0.0	-0.8	-0.3	-0.5	0.2	0.8
Depressed Affect (Nagel 2018)	0.4	0.8	2.6	-0.0	0.8	0.5	-1.6	-0.7	0.2	0.5	1.6	-0.6
Depression (Nagel 2018)	1.0	1.5	9.7	-0.9	-0.6	0.5	-3.1	0.2	-0.3	0.3	1.4	-0.2
Intelligence (Savage-Jansen 2018)	1.4	4.2	10.1	2.1	-3.1	2.3	-0.1	3.2	2.1	1.2	-0.1	-1.4
Neuroticism (Nagel 2018)	0.5	1.1	7.2	-0.3	-0.3	0.8	-2.7	0.1	0.1	0.7	1.2	0.2
Schizophrenia (2018)	0.5	0.9	4.5	0.1	0.7	-1.1	-0.7	-1.2	-0.6	-0.1	0.3	2.1
Schizophrenia vs Biploar Disorder	0.9	1.2	4.0	0.6	-2.0	0.8	-1.1	1.8	0.9	0.5	-0.0	-0.7
Worry (Nagel 2018)	0.3	0.7	4.6	-0.8	0.3	0.3	-2.1	-0.4	-0.5	0.1	0.1	0.4
Alzheimer’s Disease (in mother)	3.9	4.5	12.4	2.5	-1.5	2.4	0.3	2.4	2.6	0.7	3.5	0.8
Alzheimer’s Disease (in father)	1.7	1.8	5.2	1.8	-0.7	-0.1	2.3	1.1	1.6	1.6	-0.3	1.1
Alzheimer’s Disease (including proxy)	1.5	2.1	4.3	1.9	-1.1	1.3	0.8	1.5	2.0	0.6	2.1	1.1
Crohns Disease (2017)	4.0	8.7	19.5	-4.1	2.0	-3.8	-1.3	-3.0	-4.4	-1.7	-2.3	2.2
Irritable Bowel Disease (IBD)	2.6	6.2	13.7	-3.3	2.4	-3.0	0.1	-2.9	-3.7	-1.0	-1.2	2.5
Ulcerative Colitis (UC)	1.6	2.9	6.0	-1.5	2.4	-1.8	1.1	-2.4	-2.0	-0.6	-0.2	1.9
Major Depression (MDD)	0.9	1.1	2.0	-1.1	0.7	-0.7	-1.4	-1.2	-1.1	-1.2	-0.2	-1.1
Reaction Time	0.6	1.1	3.0	0.7	-0.9	1.6	-0.2	1.4	1.1	0.6	-0.0	-1.7
Verbal and Numeric Reasoning (VNR)	1.0	2.4	3.9	2.0	-1.3	1.9	0.5	1.7	1.8	2.0	-1.1	-1.1
Breast Cancer	1.3	3.1	5.6	-0.7	2.3	-2.3	2.1	-2.4	-1.2	0.1	-2.3	0.4
Ovarian Cancer	0.3	0.4	2.7	0.2	0.1	-0.4	0.4	0.1	-0.1	1.6	-0.7	0.6
Prostate Cancer	1.1	1.5	3.9	0.9	-2.0	1.0	-0.5	1.8	1.3	1.4	-0.3	-0.9
Age at First Birth	0.4	0.5	1.2	0.3	0.7	-1.0	0.6	-1.1	0.3	0.3	-0.7	-1.0
Bipolar Disorder (2011)	0.2	0.2	0.5	0.7	-0.2	0.7	-0.2	0.4	0.6	0.5	0.5	-0.2
Body Mass Index (BMI) (2010)	0.7	1.0	3.4	0.8	-0.1	1.8	-0.6	0.8	1.0	0.8	1.3	-0.3
Coronary Artery Disease (CAD)	2.8	3.3	12.9	1.9	-1.0	1.8	-1.7	1.2	2.1	0.8	3.6	-0.0
Crohns Disease (2012)	2.1	3.4	8.4	-2.6	1.0	-2.1	-0.6	-1.5	-2.9	-1.7	-1.7	1.4
Mean Putamen Volume	0.3	0.3	2.0	0.6	0.3	0.4	0.2	-0.2	0.2	1.4	0.2	0.1
Fasting Glucose	1.5	1.8	6.0	0.8	-1.1	2.4	-1.3	1.2	1.3	0.2	0.8	-1.5
HbA1C	5.4	6.0	12.7	2.9	-0.9	3.6	1.0	1.8	3.3	3.1	2.7	0.4
HDL Cholesterol	0.2	0.4	1.3	-0.7	-0.6	-0.4	0.1	0.6	-0.6	-0.3	0.6	1.1
LDL Cholesterol	0.3	0.5	1.3	1.0	0.0	1.0	0.1	0.1	1.0	0.3	1.1	0.4
Lupus	3.1	4.6	9.0	-2.6	1.3	-2.7	-1.3	-1.7	-3.0	-2.6	-2.2	1.0
Neuroticism (2016)	0.9	1.4	8.9	0.2	-0.7	0.6	-3.0	0.5	0.5	-0.2	1.4	0.2
Primary Biliary Cirrhosis	0.9	1.2	1.8	-1.4	0.9	-1.1	-0.9	-1.0	-1.4	-1.3	-1.0	-1.1
Rheumatoid Arthritis	4.9	6.8	15.4	-3.3	0.0	-2.7	-1.9	-1.1	-3.4	-3.9	-3.2	-0.7
Schizophrenia (2014)	0.6	1.2	3.2	0.6	-1.8	0.3	-1.7	1.7	0.4	0.6	1.1	0.3
Triglycerides	0.3	0.6	2.4	0.6	0.2	0.6	0.1	-0.0	0.6	1.1	-0.6	-1.5
Type 2 Diabetes (T2D) (2012)	2.0	2.3	8.3	0.6	-1.1	2.9	-0.0	1.5	1.1	1.3	2.2	-0.9
Ulcerative Colitis	0.4	0.5	1.9	-1.4	-0.1	-0.5	-0.2	0.1	-1.3	-0.7	0.3	-0.3
Blood Eosinophil Count	1.5	11.3	21.3	1.5	-4.3	4.6	-1.6	4.5	2.8	3.2	0.7	-4.3
Blood Platelet Count	0.6	6.6	12.0	3.5	3.1	1.5	2.5	-2.2	2.5	1.1	3.0	2.9
Blood Red Count	2.2	20.8	41.5	3.5	-6.0	6.4	-3.6	5.6	5.1	4.1	3.3	-0.8
Blood White Count	2.8	21.0	45.4	4.7	-3.9	6.7	-1.4	4.8	5.7	3.1	6.1	-1.5
Heel T-Score	1.1	8.9	26.3	-5.1	1.8	-3.5	-1.4	-2.7	-4.9	-1.6	-1.5	0.5
BMI	1.6	9.3	21.7	1.9	-3.0	4.7	-1.8	3.8	3.0	0.6	4.6	-0.7
Height	5.3	101.4	196.0	-10.4	8.7	-14.0	2.2	-11.5	-12.6	-8.8	-9.8	8.1
Waist Hip Ratio (WHR)	0.2	1.0	2.6	0.8	1.1	0.0	1.5	-1.1	0.5	0.4	-0.6	1.6
Systolic Blood Pressure	0.4	1.8	5.4	0.4	-2.2	0.9	-0.6	1.5	0.7	0.7	-1.0	-2.3
Smoking Status	0.8	1.9	5.0	2.2	0.9	0.6	1.7	-0.1	1.9	1.9	-0.3	0.4
Allergy or Eczema	1.1	2.8	6.9	-0.4	1.9	-2.2	0.9	-2.6	-0.9	-0.6	-2.5	-1.1
Cardiovascular Disease	2.4	7.9	16.7	3.4	-2.0	4.1	-0.1	2.6	3.9	3.2	2.4	0.5
Hypothyroidism (self reported)	0.2	0.5	1.4	-0.4	-0.7	0.1	0.8	1.2	-0.7	0.6	-1.0	0.6
Respiratory disease	1.9	4.1	9.5	-1.4	2.0	-2.2	-0.2	-2.2	-2.1	-2.0	-3.1	-1.8
Type 2 Diabetes (T2D) (2018)	3.2	6.1	15.3	0.9	-3.4	3.9	-2.7	2.9	2.3	0.8	1.9	-1.2
Lung FEV1/FVC ratio	13.4	67.9	139.2	7.0	-9.9	10.1	-3.9	11.8	9.3	4.0	8.3	-6.0
Lung FVC	1.1	5.8	16.2	1.5	3.2	-1.8	4.0	-2.7	0.2	0.7	-2.7	2.2
Neuroticism	0.7	1.6	8.9	-1.0	-0.6	0.6	-3.0	0.2	-0.5	0.4	1.5	-0.9
Chronotype (morning person)	0.3	0.7	1.7	-1.0	1.3	-0.4	-1.1	-1.1	-0.9	-0.4	-0.5	-0.3
Hair Pigment	0.3	9.2	20.5	-4.0	1.2	-4.2	-0.2	-2.6	-4.5	-2.6	-3.0	2.1
Tanning	0.1	0.8	1.6	0.4	1.0	-1.1	0.4	-0.7	-0.2	-1.1	1.0	1.3
Hand grip strength (left)	1.4	3.6	10.3	-2.0	-1.6	-2.9	-0.8	0.6	-2.1	-3.2	-0.1	1.3
Number of treatments/medications taken	1.3	2.3	5.4	1.2	-2.3	1.8	-0.6	2.2	1.4	0.4	0.4	-1.7
Average weekly spirits intake	3.1	3.8	8.4	-0.6	2.3	-2.3	1.1	-2.9	-1.5	-2.7	-1.7	1.1
Sensitivity / hurt feelings	0.8	1.4	5.4	-0.5	-2.3	0.7	-1.8	1.7	-0.1	-0.3	0.4	-0.2
Frequency of depressed mood in last 2 weeks	0.9	1.2	6.4	-1.2	-0.6	0.4	-2.5	0.3	-0.8	-0.1	1.2	-0.6
Hearing difficulty/problems: Yes	0.2	0.3	1.1	0.4	0.5	0.3	0.2	0.1	0.3	-0.6	1.0	0.8
Relative age of first facial hair	1.1	2.2	6.4	2.5	-0.4	0.9	1.3	1.0	2.3	1.9	0.6	-0.7
Other serious medical condition/disability diagnosed by doctor	1.0	1.3	4.7	2.2	0.8	0.3	1.4	-0.1	1.3	0.2	1.3	1.0
Ever used hormone-replacement therapy (HRT)	0.9	1.1	3.3	0.5	-1.0	1.2	0.7	1.2	0.2	1.8	-1.2	-0.9
Ever had hysterectomy (womb removed)	0.4	0.4	1.3	-0.0	1.1	0.5	0.2	-1.0	-0.3	-0.1	1.0	-0.1
Systolic blood pressure, automated reading	0.4	1.2	3.5	-0.4	-1.7	0.4	-1.4	1.3	0.1	-0.8	0.5	-1.9
Eye problems/disorders: Diabetes related eye disease	1.0	1.1	4.7	-0.1	-0.9	1.5	-0.0	0.8	0.2	1.0	0.2	-2.2
Angina	0.2	0.3	1.0	0.5	0.3	0.1	-0.6	-0.5	0.2	-0.3	1.0	0.6
Medication for hormone replacement therapy	1.5	1.7	3.7	0.7	-1.6	1.8	0.1	1.8	0.7	1.9	-0.1	-1.0
Vitamin and mineral supplements	1.1	1.5	4.9	-1.6	0.6	-1.1	-0.5	-0.5	-1.7	-2.2	-1.0	0.1
Supplements: Zinc	1.7	1.9	5.0	0.5	-2.2	1.6	-1.4	2.2	1.0	1.0	0.5	-0.8
Medication: Co-codamol	0.9	1.0	2.1	-1.1	1.2	-0.7	0.4	-1.2	-1.1	-0.5	0.9	1.4
Medication: Metformin	1.6	2.2	8.2	1.0	-1.4	2.9	-0.5	1.5	1.7	1.3	1.1	-0.7
Diabetes (father)	0.9	1.1	3.7	0.1	-1.4	1.1	-1.9	1.1	0.6	-0.6	0.5	0.9
Diabetes (mother)	1.6	2.1	7.5	0.1	-0.6	2.6	-0.7	0.6	0.9	0.9	2.7	-1.4
Severe depression (siblings)	0.4	0.5	1.9	-1.1	-0.1	-0.1	-0.1	-0.0	-1.4	0.1	-0.7	0.7
Pack years adult smoking proportion	0.7	1.0	3.7	0.1	-0.8	1.9	-0.3	1.4	0.6	1.3	0.7	0.6
Impedance of leg (right)	4.9	23.9	50.8	-5.1	6.0	-5.9	-0.2	-7.1	-5.8	-3.9	-2.7	3.2
Leg fat-free mass (left)	0.2	1.2	4.4	-0.1	-2.1	0.6	-0.4	1.9	0.0	-0.8	0.3	1.1
Trunk fat percentage	0.7	2.7	5.8	-1.6	1.8	-0.9	-1.2	-1.5	-2.0	-2.4	0.7	1.9
Hand grip strength (right)	1.6	4.5	10.8	-2.9	-1.8	-3.3	-1.2	0.4	-2.6	-2.7	-0.7	1.4
Townsend deprivation index at recruitment	1.0	1.4	4.5	0.8	-0.4	2.1	-1.1	0.7	1.2	0.6	1.6	-1.0
Current tobacco smoking	1.1	1.9	3.4	1.5	0.1	1.9	0.6	0.7	1.6	1.8	1.5	1.7
Average weekly fortified wine intake	1.7	2.0	6.3	-2.5	0.3	-1.5	0.5	-1.0	-2.5	-1.0	-1.1	-0.1
Maternal smoking around birth	1.2	1.7	3.5	0.5	-1.5	1.7	0.1	1.7	0.7	0.9	1.9	1.4
Fed-up feelings	0.3	0.5	2.9	-0.2	-0.4	0.7	-1.7	0.5	0.1	0.3	0.7	-0.3
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.3	8.1	-1.0	-1.2	0.5	-2.9	0.5	-0.3	-0.2	0.5	-0.1
Relative age voice broke	0.4	0.7	2.6	0.7	-0.1	0.9	0.8	0.6	0.8	1.6	0.3	-0.6
Taking other prescription medications	0.5	0.7	5.0	-0.5	-0.4	-0.0	-0.8	0.2	-0.6	-2.2	0.3	0.4
Age when periods started (menarche)	1.5	3.6	10.8	-1.7	1.8	-3.3	0.3	-2.5	-1.9	-1.5	-1.5	0.9
Bilateral oophorectomy (both ovaries removed)	0.1	0.1	0.3	-0.1	0.5	0.4	0.6	-0.1	-0.3	-0.1	-0.0	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.8	1.9	4.1	-2.0	1.0	-1.5	-0.6	-1.4	-2.0	-0.2	-1.5	1.0
Tinnitus: Yes, but not now, but have in the past	0.2	0.2	0.8	0.3	0.1	0.4	0.2	-0.2	0.3	0.9	-0.3	0.7
Qualifications: CSEs or equivalent	1.1	1.4	4.7	-0.2	-1.3	1.3	0.1	1.3	0.5	0.4	2.2	1.6
Serious illness, injury or assault to yourself	0.2	0.2	0.6	0.4	0.6	0.8	0.7	-0.1	0.1	-0.3	0.2	0.5
High blood pressure	2.4	6.8	12.7	2.9	-2.8	3.4	-0.1	3.2	3.2	3.6	0.7	-0.1
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.9	0.3	0.9	-0.9	0.9	-1.4	0.2	0.1	-1.2	-0.9
Multivitamins +/- minerals	1.3	1.7	5.0	1.6	-0.4	1.5	0.4	0.4	1.7	2.2	1.1	-0.6
Stomach or abdominal pain in last month	0.7	0.8	4.9	-0.4	-0.3	-0.0	-0.1	0.2	-0.0	0.5	1.5	2.2
Supplements: Glucosamine	0.5	0.6	1.5	0.6	1.2	-0.8	0.4	-1.1	0.1	0.4	-1.2	0.3
Diverticular disease/diverticulitis (self-reported)	0.8	0.9	3.2	-0.8	0.6	-0.1	-1.4	-0.6	-0.6	-1.8	0.9	-0.6
Medication: Atenolol	0.5	0.7	1.7	0.9	-1.3	0.8	-0.8	0.8	1.0	0.3	0.2	-0.8
Medication: Levothyroxine sodium	0.9	1.5	3.9	1.2	1.0	1.0	2.0	0.2	0.9	1.6	0.2	1.6
Sitting height	0.3	2.1	8.6	-0.2	-0.3	-1.2	1.8	0.1	-0.5	1.1	-1.9	2.9
Chronic bronchitis/emphysema (father)	0.2	0.2	1.0	0.1	0.3	0.6	-1.0	-0.4	-0.0	-0.5	0.6	-0.1
High blood pressure (mother)	2.8	3.9	9.2	2.0	-1.1	3.0	0.1	1.2	2.8	1.1	2.2	-2.2
Body mass index (BMI)	1.7	7.2	18.4	1.6	-2.7	4.3	-1.7	3.6	2.3	0.6	3.7	-0.9
Impedance of leg (left)	5.4	26.1	53.7	-5.4	6.1	-6.4	-0.4	-7.3	-6.1	-4.1	-3.5	2.7
Leg predicted mass (left)	0.2	1.1	4.1	0.0	-2.0	0.6	-0.3	1.9	0.1	-0.8	0.3	1.1
Trunk fat mass	0.5	2.2	5.5	-1.6	1.1	-0.7	-1.2	-1.0	-1.9	-2.3	0.6	2.0
Waist circumference	0.2	0.9	2.4	0.2	-0.5	1.6	-0.9	0.8	0.4	-0.7	1.5	1.1
Number of incorrect matches in round	1.5	2.5	6.3	1.4	-1.4	1.7	0.4	1.8	1.3	2.5	-0.6	-2.1
Past tobacco smoking	1.8	3.3	8.5	-1.3	-1.9	2.1	-2.5	1.6	-0.1	-1.3	2.9	-1.1
Alcohol usually taken with meals	0.3	0.5	2.8	-0.4	0.4	-1.0	0.1	-0.3	-0.2	-0.4	-1.7	-0.6
Nervous feelings	0.3	0.6	2.8	-1.0	-0.1	-0.5	-1.7	-0.2	-0.7	-0.7	-0.1	0.2
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	3.1	0.3	-1.1	1.8	-1.1	0.9	0.8	1.5	0.6	-1.1
Hearing difficulty/problems with background noise	0.3	0.5	1.3	0.2	-0.5	1.0	-0.7	0.6	0.2	0.8	1.1	-0.5
Hair/balding pattern: Pattern 2	2.1	2.7	7.4	1.3	2.7	-0.7	2.4	-2.0	0.3	1.2	-1.6	0.9
Had menopause	1.3	1.6	5.0	1.7	-0.6	1.7	0.6	1.1	1.4	2.2	-0.1	-0.3
Had other major operations	0.9	1.1	4.2	1.1	-0.3	1.0	-0.2	1.1	1.2	0.2	2.0	0.6
Forced vital capacity (FVC)	3.4	13.2	27.0	-1.5	4.0	-5.2	3.7	-4.7	-2.7	-1.9	-3.8	3.5
Heel bone mineral density (BMD) T-score, automated (right)	2.6	5.9	13.2	-3.4	1.6	-2.9	-1.0	-2.2	-3.6	-1.8	-2.0	2.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.2	-0.3	-0.5	-0.1	-0.2	0.2	-0.5	-1.2	-1.5	-1.0
Qualifications: None of the above	1.0	2.1	5.1	-0.5	2.0	-0.1	-0.9	-1.5	-0.7	-1.3	2.3	2.1
Financial difficulties in last 2 years	1.5	2.0	5.8	-0.7	-1.2	1.6	-2.4	0.9	-0.2	-1.3	2.2	-0.6
Mouth/teeth dental problems	1.5	2.4	5.8	1.4	-2.3	1.6	-0.0	2.4	1.8	0.5	-0.4	-1.4
Heart attack	0.4	0.6	1.2	0.7	-1.1	0.2	-0.7	1.0	0.7	-0.2	0.1	1.1
Allergy	0.3	0.7	2.7	0.4	-0.1	1.1	0.1	0.7	0.5	0.5	1.6	0.9
Pain all over the body in last month	0.5	0.5	2.5	-0.7	0.3	-0.2	0.1	-0.5	-0.7	-0.9	-1.6	0.1
Diabetes (self-reported)	1.8	2.9	7.1	0.4	-2.7	2.6	-1.7	2.2	1.3	0.1	1.3	-0.8
Hayfever/allergic rhinitis (self-reported)	4.7	6.3	14.9	-2.5	2.4	-3.9	0.7	-3.5	-3.0	-1.5	-2.3	0.0
Medication: Ramipril	0.4	0.6	3.3	-0.3	-0.9	-0.3	-0.2	0.4	-0.4	-0.4	-1.8	0.4
Medication: Simvastatin	0.8	1.2	2.2	1.4	0.4	1.2	0.7	-0.0	1.5	1.0	1.2	1.4
Fluid intelligence score	1.7	3.6	5.7	2.3	-1.9	2.4	-0.0	2.2	2.3	2.2	-1.0	-1.3
Illnesses of siblings	2.2	3.1	6.6	-0.8	1.8	-2.3	2.1	-1.7	-1.2	-0.1	-2.6	1.9
Neuroticism score	1.6	3.2	14.8	-1.6	-2.0	1.1	-3.8	1.5	-0.7	0.2	1.4	-1.3
Weight	0.2	1.2	3.2	-1.1	-0.6	0.3	-1.1	0.6	-1.0	-1.6	0.7	1.8
Impedance of arm (right)	4.3	19.9	49.6	-2.7	6.5	-5.9	1.6	-7.0	-4.3	-2.6	-3.2	2.7
Arm fat percentage (right)	0.5	2.0	9.0	0.6	-0.3	2.2	-1.2	1.1	0.7	-0.6	3.0	-0.1
Trunk fat-free mass	0.3	1.5	5.4	-1.0	-2.3	0.1	-0.7	1.8	-0.7	-1.0	-0.1	1.2
Hip circumference	0.4	1.5	4.5	-1.7	0.3	-0.1	-1.2	-0.1	-1.5	-2.1	0.7	1.4
Time employed in main current job	0.3	0.4	2.1	0.0	0.7	0.0	0.2	-0.5	-0.0	0.4	0.5	-1.4
Alcohol intake versus 10 years previously	1.5	2.2	6.8	-2.0	0.0	-1.4	-0.2	-0.1	-2.6	-1.9	-0.0	1.9
Father’s age at death	0.8	1.1	4.1	-0.1	1.0	-1.6	0.9	-1.0	-0.3	0.5	-2.0	-0.3
Worrier / anxious feelings	0.5	1.0	2.4	-1.3	-0.1	-0.8	-1.6	-0.6	-1.2	0.2	-1.5	0.3
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	1.2	-0.8	0.8	0.3	-0.7	-1.1	-0.9	-0.3	0.8	0.7
Falls in the last year	0.3	0.4	1.0	1.0	-0.5	0.6	-0.3	0.5	0.9	0.7	0.1	-0.6
Hair/balding pattern: Pattern 3	0.3	0.5	1.2	-1.1	-0.9	-0.7	-0.1	0.5	-0.8	-0.4	-0.9	-0.1
Number of live births	0.3	0.4	1.1	-1.1	0.2	-0.1	-0.4	0.0	-0.9	0.4	0.9	0.3
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	6.8	-0.2	1.5	-2.6	2.3	-1.8	-0.8	-1.4	-1.4	1.8
Pulse rate	0.9	1.6	3.6	0.6	-0.9	1.9	-0.6	1.6	0.9	-0.1	1.9	-1.4
Happiness	0.4	0.5	1.5	-0.3	-0.5	0.6	-1.2	0.0	-0.2	1.0	-1.2	-0.4
Noisy workplace	1.5	1.8	6.4	-0.0	2.5	-0.8	1.6	-1.7	-0.7	-0.3	0.4	1.7
Qualifications: A levels/AS levels or equivalent	0.7	1.5	6.5	-0.6	0.2	-1.8	0.4	-0.6	-1.1	-1.0	-2.5	-0.7
Serious illness, injury or assault of a close relative in last 2 years	2.2	2.5	4.8	2.2	0.8	1.9	1.4	0.2	2.2	2.1	1.7	0.4
Mouth/teeth dental problems: Dentures	1.8	3.0	4.9	-2.0	2.0	-2.0	-1.7	-1.8	-2.2	-1.7	0.9	0.8
Asthma	2.1	4.0	5.8	-2.3	0.4	-2.1	-1.8	-1.1	-2.4	-2.2	-2.4	-2.4
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	4.7	-0.0	-1.9	1.4	-1.0	2.2	0.7	0.1	1.0	-2.0
Medication: Cholesterol lowering	0.7	1.0	2.1	1.3	0.1	1.4	0.9	0.2	1.3	1.1	1.3	0.3
Depression (self-reported)	0.3	0.3	1.2	-0.3	0.2	-0.7	-0.7	-0.6	-0.5	-1.1	0.1	0.1
Medication: Lansoprazole	0.9	1.1	2.6	1.0	-1.1	1.6	-0.4	1.3	1.2	1.0	0.6	0.4
Prospective memory result	0.4	0.4	2.2	-0.5	0.3	0.6	-0.3	0.1	-0.1	0.7	0.5	-1.5
Lung cancer (father)	2.5	2.9	11.3	0.4	0.2	2.3	1.3	0.5	0.9	2.2	3.4	1.4
Illnesses of mother	5.5	6.8	16.4	-2.7	2.1	-4.0	-0.1	-2.1	-3.5	-2.4	-2.6	2.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.9	2.8	7.1	-0.5	1.2	-2.7	2.2	-1.3	-1.1	-1.4	-2.3	1.1
Pulse wave Arterial Stiffness index	1.7	2.0	4.8	2.2	0.1	1.5	0.8	0.7	2.1	1.5	1.0	1.5
Impedance of arm (left)	5.9	27.3	61.6	-3.6	7.0	-7.1	2.2	-7.8	-5.3	-2.9	-4.6	3.0
Arm fat mass (right)	0.4	1.6	5.1	-0.0	-0.9	1.8	-1.4	1.3	0.2	-1.2	2.3	0.3
Trunk predicted mass	0.3	1.4	5.5	-0.9	-2.3	0.1	-0.7	1.8	-0.6	-1.0	-0.2	1.1
Standing height	3.7	36.3	73.2	-6.0	4.5	-8.6	1.0	-6.4	-7.4	-5.1	-6.4	5.7
Length of working week for main job	2.1	2.3	4.6	-2.1	0.8	-1.2	-1.5	-1.4	-2.0	-2.0	-1.5	-0.3
Exposure to tobacco smoke at home	0.3	0.4	2.1	-0.4	0.3	-0.2	-0.0	-0.5	-0.3	-0.2	-1.4	0.7
Breastfed as a baby	3.2	4.0	13.8	0.8	1.7	-1.1	3.5	-1.0	-0.2	1.6	-1.4	3.7
Tense / ‘highly strung’	0.4	0.6	3.6	-0.1	-0.9	0.7	-1.9	0.7	0.1	-0.4	-0.5	-0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	4.4	-0.0	-1.5	0.4	-2.1	0.6	0.5	-0.4	1.2	-0.8
Hair/balding pattern: Pattern 4	0.5	1.3	3.3	-1.2	-1.8	-0.1	-1.7	1.3	-0.7	-0.8	-0.0	-1.0
Birth weight of first child	0.4	0.8	2.3	0.5	-1.4	0.6	-1.3	1.5	0.5	0.1	-0.6	-0.4
Peak expiratory flow (PEF)	0.4	1.0	3.7	0.4	-1.1	-0.5	-0.6	0.9	0.5	-1.5	1.9	-0.3
Pulse wave reflection index	0.5	0.6	1.2	0.8	0.7	0.2	1.1	-0.5	0.5	0.9	-1.0	0.9
Ever highly irritable/argumentative for 2 days	0.3	0.3	0.8	-0.5	-0.4	0.5	-0.9	0.1	-0.7	-0.9	-0.1	-0.5
Loud music exposure frequency	0.3	0.3	1.8	0.5	-0.1	-0.2	0.2	-0.0	0.1	0.4	-1.3	-0.6
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	5.4	0.2	1.2	-1.1	1.8	-1.4	-0.2	0.1	-2.3	0.4
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	3.0	-0.4	1.5	-0.7	1.7	-1.6	-0.6	0.6	-1.4	1.0
Blood clot in the leg (DVT)	0.7	0.9	3.4	-0.3	-1.5	0.1	-1.9	1.2	0.1	-0.6	0.3	-0.0
Medication: Paracetamol	0.6	1.0	3.9	-0.8	-0.5	1.0	-0.9	0.5	-0.4	0.6	2.0	-1.2
Headache pain in last month	1.3	2.2	10.6	-0.6	-1.1	1.9	-1.2	1.4	0.0	0.7	3.3	0.1
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	4.2	-1.9	0.5	-2.0	-1.0	-0.9	-1.9	-1.3	-1.1	-0.7
Glaucoma (self-reported)	0.8	1.0	2.3	0.2	-1.0	0.1	-1.5	1.0	0.2	-1.0	1.0	-1.5
Gout (self-reported)	0.1	0.2	0.8	-0.5	0.1	0.5	0.5	0.1	-0.2	0.3	0.9	-0.1
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	3.1	0.3	0.6	0.4	1.7	0.4	0.1	1.4	-0.4	1.5
Medication: Amlodipine	0.4	0.5	2.1	1.4	0.0	0.6	0.7	0.2	1.0	0.9	-0.1	-0.1
Medication: Ventolin 100micrograms inhaler	1.3	1.7	9.5	-0.0	-1.2	0.4	-1.9	0.4	0.1	-0.4	-0.2	-3.1
Birth weight	0.5	1.1	3.4	-1.1	0.4	-1.8	-0.0	-0.3	-1.1	-1.7	0.3	0.6
Chronic bronchitis/emphysema (mother)	0.9	1.0	3.8	-1.2	-0.6	0.6	-1.4	0.3	-0.8	-1.0	0.1	-1.9
High blood pressure (siblings)	1.4	2.0	3.8	1.0	-1.6	1.9	-0.9	1.5	1.4	0.0	1.7	-1.7
Forced vital capacity (FVC), Best measure	3.9	14.4	30.7	-2.3	3.7	-5.5	3.4	-4.4	-3.4	-2.2	-5.0	2.7
Body fat percentage	0.4	1.5	3.4	-1.2	0.8	0.4	-1.6	-0.5	-1.2	-1.8	1.7	1.1
Leg fat percentage (right)	0.6	2.0	7.9	-1.0	-0.0	1.5	-2.1	0.3	-0.7	-1.5	2.8	0.4
Arm fat-free mass (right)	0.5	2.4	8.5	-1.3	-2.9	0.5	-1.6	2.4	-0.7	-1.3	-0.1	0.8
Exposure to tobacco smoke outside home	1.0	1.3	3.9	-2.0	-0.5	0.2	-0.6	0.1	-1.4	-1.3	1.0	1.5
Comparative body size at age 10	1.0	2.7	8.4	0.7	2.4	-1.6	2.9	-2.0	0.0	-0.5	-0.8	1.5
Number of full brothers	2.1	2.7	7.0	-0.5	-2.4	1.6	-2.6	2.6	-0.1	0.5	1.4	-0.3
Worry too long after embarrassment	2.2	3.8	12.0	-1.2	-3.5	1.2	-3.0	2.7	-0.3	0.1	-0.1	-1.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.3	3.0	7.4	-0.6	2.5	-1.9	2.3	-2.7	-0.9	-0.2	-1.8	0.8
Wheeze or whistling in the chest in last year	0.6	1.1	2.1	-1.3	1.1	-0.8	-0.5	-1.2	-1.4	-0.4	-1.5	0.4
Number of children fathered	0.2	0.2	0.9	0.6	0.1	0.1	0.3	-0.5	0.3	-0.2	1.0	-0.4
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	4.9	-0.4	-0.6	-0.7	-0.6	0.3	-0.7	-0.6	-2.2	-1.1
Age at first live birth	1.5	2.6	8.0	0.1	1.4	-2.5	1.8	-1.7	-0.8	-0.5	-2.8	-0.4
Pulse wave peak to peak time	2.5	3.0	6.9	-2.6	-0.0	-2.1	-0.8	-0.9	-2.6	-1.9	-1.5	-1.2
Health satisfaction	0.6	0.7	4.0	0.5	0.0	2.0	-0.2	0.3	0.8	0.2	1.1	-0.8
Shortness of breath walking on level ground	0.3	0.4	1.2	-0.7	0.3	0.5	-1.1	-0.4	-0.8	-0.6	-0.3	-0.6
Qualifications: College or University degree	0.5	1.7	5.8	0.4	0.5	-0.4	1.9	-0.5	0.4	2.0	-2.4	-0.8
Eye problems/disorders: None of the above	1.1	1.3	4.0	-0.2	2.0	-0.5	1.0	-1.7	-0.6	-0.8	-0.8	1.3
Mouth/teeth dental problems: Loose teeth	0.7	0.9	1.7	1.3	1.0	-0.0	1.2	-1.0	0.7	0.8	0.2	1.1
Emphysema/chronic bronchitis	0.2	0.2	0.8	0.5	-0.1	0.4	0.9	0.4	0.3	0.4	-0.6	0.3
Medication for pain relief, constipation, heartburn	1.2	2.1	5.1	-0.9	1.2	-2.3	0.2	-1.7	-1.5	-1.0	-2.2	0.8
Neck or shoulder pain in last month	0.7	1.0	2.5	0.7	-1.0	1.4	-0.6	1.2	0.9	0.2	1.6	-0.8
Medication: Blood pressure	1.2	2.1	4.6	2.1	-1.3	1.9	0.5	1.4	1.8	1.6	0.2	0.8
Angina (self-reported)	0.3	0.4	1.5	0.8	0.3	0.4	-0.4	-0.3	0.6	-0.1	1.2	0.7
Migraine (self-reported)	0.1	0.1	0.4	0.1	0.2	0.4	0.2	-0.1	0.1	-0.6	0.7	0.1
Medication: Ibuprofen	1.3	1.6	3.5	0.2	-1.7	1.7	-0.7	1.9	0.8	1.0	0.8	-1.4
Medication: Allopurinol	0.2	0.3	1.4	0.1	0.1	0.5	0.8	0.5	0.1	1.2	0.2	-0.0
Medication: Omeprazole	0.3	0.4	1.3	-0.0	1.1	0.3	0.9	-0.9	-0.5	0.1	0.3	0.1
Medication: Seretide 50 evohaler	0.6	0.7	2.0	1.2	-0.3	0.5	0.3	0.8	0.8	1.4	-0.7	-0.7
Mean time to correctly identify matches	0.6	1.1	2.6	1.1	-0.4	1.6	-0.2	1.0	1.3	0.8	0.2	-1.6
Heart disease (mother)	0.1	0.1	0.5	0.2	0.7	0.2	-0.1	-0.7	0.2	0.1	-0.4	-0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.5	1.6	-0.5	0.5	-0.9	-0.8	-0.4	-0.4	-1.3	0.9	0.5
Whole body fat mass	0.3	1.4	3.9	-1.2	0.1	0.4	-1.6	-0.0	-1.2	-2.0	1.3	1.2
Leg fat mass (right)	0.4	1.6	4.7	-0.8	-0.4	1.2	-1.7	0.5	-0.5	-1.6	2.2	1.0
Arm predicted mass (right)	0.4	2.1	7.1	-1.4	-2.7	0.4	-1.4	2.1	-0.8	-1.3	-0.4	0.9
Pulse rate, automated reading	2.6	8.3	16.1	3.7	-1.4	3.8	1.6	2.9	4.0	3.0	2.8	0.0
Alcohol intake frequency.	1.3	3.0	12.6	-2.0	-1.0	1.6	-3.5	1.6	-1.2	-0.1	1.5	0.0
Comparative height size at age 10	2.9	15.7	28.5	-3.4	4.4	-5.0	1.4	-5.3	-4.4	-3.5	-4.0	2.7
Number of full sisters	2.0	2.4	8.0	-0.4	-1.6	2.3	-1.4	1.9	0.3	0.5	2.8	0.1
Suffer from ‘nerves’	0.8	1.3	6.0	-1.7	0.5	-0.3	-2.5	-0.5	-1.1	-0.3	0.7	0.5
Overall health rating	0.6	1.3	6.8	0.8	0.3	1.2	-0.8	-0.0	0.7	-0.2	2.6	1.1
Chest pain or discomfort	0.2	0.2	0.6	0.1	0.8	0.4	0.5	-0.4	0.2	0.1	0.8	0.5
Had major operations	1.1	1.3	2.3	-1.1	0.8	-0.9	-0.5	-0.8	-1.5	-1.4	-1.0	1.5
Age at last live birth	1.2	1.8	4.6	-1.0	0.5	-2.2	0.1	-1.2	-1.5	-1.5	-1.8	0.7
Family relationship satisfaction	0.5	0.7	2.7	-0.3	0.5	0.5	-0.8	-0.6	-0.0	0.6	-1.6	-1.2
Leg pain on walking	0.6	0.8	3.2	0.1	-0.1	0.4	-1.7	0.5	0.1	0.4	1.8	-0.4
Qualifications: NVQ or HND or HNC or equivalent	1.1	1.3	3.1	-1.4	0.1	-1.2	0.7	-0.4	-1.8	-1.5	-1.4	0.4
Commuting to job workplace: Car/motor vehicle	1.3	1.5	4.3	-0.9	1.9	-0.5	1.1	-2.1	-1.3	0.0	0.7	1.2
Illness, injury, bereavement, stress in last 2 years	1.5	1.9	6.5	-1.5	-0.1	-2.6	-0.2	-0.6	-1.7	-0.8	-1.9	0.5
Medication: Aspirin	2.4	3.2	8.3	2.7	-1.4	1.8	-0.2	2.0	2.9	1.3	1.3	-0.5
Supplements: Vitamin C	0.3	0.3	1.1	0.7	-0.4	0.2	0.5	0.3	0.6	0.4	-0.4	1.0
Knee pain experienced in last month	0.3	0.5	1.4	-0.4	0.7	-0.6	-0.7	-0.9	-0.6	-0.2	0.1	1.2
Hypertension (Self-reported)	2.6	7.1	12.2	2.8	-3.0	3.5	-0.4	3.4	3.3	3.2	1.1	-0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.2	0.7	1.1	1.3	0.0	-0.1	0.5	0.6	1.5	1.3
Illnesses of father: Heart disease	2.1	3.0	6.1	2.3	-0.1	1.8	2.4	0.6	2.2	2.5	0.7	-0.7
Illnesses of siblings: Diabetes	1.6	1.9	6.3	0.5	-0.8	2.5	-1.2	1.2	1.0	1.0	2.3	-0.4
Smoking status: Previous	1.2	1.8	6.8	0.8	0.8	-1.9	1.5	-0.8	-0.2	1.1	-2.6	0.0
Forced expiratory volume in 1-second (FEV1), predicted	0.8	1.6	3.0	0.1	1.7	-1.4	1.7	-1.6	-0.3	-1.1	-0.2	1.6
Whole body fat-free mass	0.3	1.5	6.1	-0.6	-2.5	0.4	-0.7	2.1	-0.3	-1.0	-0.0	1.0
Leg fat-free mass (right)	0.2	1.2	5.2	0.1	-2.3	0.5	-0.3	2.1	0.2	-0.6	-0.1	0.7
Arm fat percentage (left)	0.3	1.2	5.6	0.2	-0.2	1.7	-1.1	0.8	0.3	-0.8	2.4	-0.0
Average weekly red wine intake	1.2	1.8	6.9	0.2	-2.1	0.9	-0.8	1.5	0.8	0.5	0.1	-2.6
Handedness (chirality/laterality): Left-handed	0.3	0.3	1.3	-0.4	0.3	-0.5	-0.3	-0.8	-0.3	-0.5	-0.2	1.1
Mood swings	0.8	1.4	6.2	-0.2	-0.4	0.8	-2.5	0.2	0.3	-0.6	2.1	-0.4
Loneliness, isolation	0.4	0.6	2.6	-0.3	-0.3	0.5	-1.6	0.3	0.0	0.0	1.0	-1.1
Long-standing illness, disability or infirmity	1.3	1.9	5.3	1.1	-1.2	1.9	-1.3	1.6	1.2	-0.1	2.3	0.5
Ever had bowel cancer screening	1.5	1.7	5.0	-0.3	2.2	-0.8	0.8	-1.9	-0.8	-0.2	0.3	2.2
Diabetes diagnosed by doctor	2.0	3.3	9.3	0.5	-2.5	3.0	-1.9	2.0	1.5	0.2	1.8	-0.5
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	3.4	0.5	-0.8	0.8	-0.0	0.8	0.5	0.1	1.9	-0.1
Friendships satisfaction	0.7	0.8	3.0	-0.0	-0.3	1.5	-1.0	0.6	0.2	1.7	0.2	-0.9
Qualifications: nursing, teaching	1.8	2.7	12.2	1.0	1.3	-0.2	3.5	-0.9	0.5	2.0	-2.2	0.1
Commuting to job workplace: Walk	1.1	1.2	3.2	0.7	-1.4	0.8	0.6	1.5	1.0	1.8	-0.3	1.0
Eye problems/disorders: Cataract	0.7	0.8	2.1	-0.0	-1.4	-0.0	-0.4	1.4	0.1	1.2	0.1	-1.2
Mouth/teeth dental problems: Mouth ulcers	1.2	2.0	3.5	-1.5	1.7	-1.2	1.3	-1.9	-1.7	0.2	-0.0	1.8
Medication for cholesterol	2.1	3.2	7.0	-1.4	2.2	-2.5	0.1	-2.6	-1.8	-2.0	0.1	1.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.3	2.7	6.6	-0.8	2.6	-1.3	0.7	-2.5	-1.2	-1.0	0.1	2.5
Back pain experienced in last month	0.3	0.4	1.5	-0.5	0.3	0.9	0.6	-0.0	-0.8	0.1	1.2	0.5
Mineral and other dietary supplements	0.4	0.5	1.9	-1.1	-0.4	0.1	-0.3	0.3	-0.8	-1.4	0.8	0.1
Breast cancer (self-reported)	0.6	0.8	1.8	0.8	-1.3	0.9	-0.8	1.3	0.9	-0.4	-0.1	-0.6
Asthma (self-reported)	1.9	3.8	5.7	-2.2	0.4	-2.1	-1.7	-1.0	-2.3	-2.2	-2.3	-2.4
Osteoporosis (self-reported)	1.3	1.6	3.8	0.1	1.9	-1.4	1.3	-1.9	-0.7	-1.0	-0.4	1.1
Osteoarthritis (self-reported)	0.9	1.2	4.1	0.6	2.0	-0.5	0.6	-2.0	-0.0	0.1	-0.7	1.0
Medication: Aspirin	2.3	3.0	8.3	2.9	-1.2	1.6	0.0	1.7	2.9	1.2	1.2	-0.5
Medication: Gliclazide	2.0	2.2	3.6	1.1	-1.9	1.6	-1.2	1.8	1.8	0.4	1.5	-1.5
Illnesses of father: None of the above (group 1)	1.4	1.7	3.8	-1.9	-0.1	-1.3	-1.9	-0.1	-1.6	-1.9	0.4	-0.1
Smoking status: Current	0.8	1.2	2.1	1.3	0.4	1.5	0.7	0.4	1.4	1.3	1.0	1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.8	0.3	1.1	-0.7	1.3	-0.9	0.2	-0.5	-0.5	0.1
Whole body water mass	0.3	1.5	6.4	-0.6	-2.5	0.5	-0.8	2.1	-0.3	-0.9	0.0	1.0
Leg predicted mass (right)	0.2	1.3	5.4	0.0	-2.3	0.5	-0.3	2.1	0.1	-0.6	-0.1	0.7
Arm fat mass (left)	0.3	1.2	3.7	-0.3	-0.5	1.4	-1.3	0.8	-0.2	-1.3	1.9	0.6
Number of self-reported non-cancer illnesses	1.2	2.1	6.6	0.3	-1.2	2.3	-1.5	1.5	0.7	0.3	2.6	0.2
Average weekly champagne plus white wine intake	2.2	3.0	7.1	-2.3	-0.9	-1.2	-1.7	0.1	-2.0	-2.0	-2.7	-1.1
Miserableness	0.4	0.7	1.2	-1.0	0.7	-0.5	-1.0	-1.0	-0.8	-0.3	1.1	0.6
Guilty feelings	0.6	0.8	2.8	-0.8	-0.1	-0.5	-1.7	-0.7	-0.8	0.0	1.6	0.5
Wears glasses or contact lenses	1.1	1.2	3.4	1.2	-0.4	-0.4	1.8	0.3	0.5	1.6	-1.7	0.1
Ever taken oral contraceptive pill	0.6	0.7	2.1	-0.4	-1.4	0.3	-0.1	1.3	-0.1	-0.2	1.3	0.6
Hearing aid user	0.3	0.3	1.8	-0.2	-0.1	0.1	0.2	0.2	0.1	-0.2	1.0	-1.3
Mother’s age at death	0.8	1.0	3.4	0.2	-0.3	-0.8	1.5	-0.0	0.1	1.3	-1.9	-0.7
Financial situation satisfaction	1.7	2.1	5.5	-1.2	-1.9	1.7	-1.8	1.2	-0.5	0.0	0.8	-2.3
Tinnitus: Yes, now most or all of the time	1.2	1.4	5.7	2.4	0.9	0.1	1.4	0.1	1.6	-0.4	0.4	1.1
Commuting to job workplace: Public transport	1.0	1.1	3.5	0.7	-1.5	0.0	-0.9	1.2	1.1	-0.5	0.3	-1.9
Eye problems/disorders: Glaucoma	0.5	0.6	2.3	-0.2	-0.9	-0.4	-1.5	0.6	-0.0	-1.2	0.3	-0.7
Medication: Blood pressure	2.3	4.3	8.3	1.7	-2.8	2.3	-0.7	2.9	2.3	2.4	0.2	-1.7
Pain type(s) experienced in last month: Hip pain	0.2	0.3	0.5	-0.3	0.5	-0.4	0.1	-0.6	-0.7	0.7	-0.2	0.6
Supplements: Fish oil (including cod liver oil)	1.4	1.8	5.1	2.3	-0.6	1.2	0.4	1.0	1.9	1.9	0.2	-0.9
High cholesterol (Self-reported)	1.3	2.3	4.1	1.7	-1.1	2.0	-0.1	1.6	2.0	0.7	1.9	1.4
Medication: Bendroflumethiazide	2.7	4.1	13.4	1.5	-3.7	1.8	0.4	3.4	1.6	1.8	0.4	-0.3
Medication: Paracetamol	0.9	1.4	3.1	-1.4	-0.9	0.7	-1.7	0.5	-0.9	0.2	1.4	-1.8
Medication: Lisinopril	1.9	2.5	5.4	2.3	0.0	1.8	1.3	0.9	2.0	2.1	1.7	-0.2
Medication: Atorvastatin	1.1	1.3	3.7	0.2	-1.6	1.4	-0.1	1.6	0.5	-0.6	1.9	-0.6
Illnesses of father: High blood pressure	0.5	0.6	2.1	0.4	-0.1	0.7	1.4	0.3	0.5	1.0	-0.7	-0.8
Alcohol drinker status: Never	2.3	2.7	8.7	-2.8	-0.5	-0.5	-3.0	-0.5	-2.1	-1.5	-0.4	-0.6
Ever smoked	2.6	4.6	10.3	0.6	2.8	-2.4	2.5	-2.4	-0.8	1.1	-3.2	2.0
Basal metabolic rate	0.2	1.3	3.7	-0.8	-1.9	0.2	-0.8	1.6	-0.6	-1.3	0.1	1.3
Leg fat percentage (left)	0.5	1.9	6.5	-0.9	-0.1	1.4	-2.2	0.4	-0.6	-1.5	2.5	-0.0
Arm fat-free mass (left)	0.4	2.1	7.1	-0.8	-2.7	1.0	-1.4	2.4	-0.2	-1.2	0.4	0.7
Number of operations (self-reported)	0.1	0.1	0.3	-0.0	-0.1	0.1	-0.2	0.5	-0.3	-0.6	-0.1	0.6
Average weekly beer plus cider intake	1.0	1.4	4.8	0.2	2.2	-0.4	0.6	-1.8	-0.2	1.6	1.0	0.9
Irritability	0.4	0.6	2.5	-0.2	-0.1	0.8	-1.6	-0.1	0.1	0.5	-0.6	-1.4
Risk taking	0.6	0.9	2.2	-1.5	0.7	-0.1	1.3	-0.9	-1.3	0.5	0.3	-0.9
Ever had prostate specific antigen (PSA) test	0.4	0.4	1.8	-0.3	-0.4	-0.5	-1.2	0.0	-0.2	-1.3	0.3	-0.2
Fractured/broken bones in last 5 years	1.5	1.9	7.3	-0.8	2.7	-1.4	0.9	-2.0	-1.1	-0.5	-0.6	-0.8
Age started oral contraceptive pill	1.9	2.4	4.4	-1.7	1.4	-2.1	-0.3	-1.7	-2.1	-1.2	-1.4	1.1
Diastolic blood pressure, automated reading	2.1	6.5	12.5	2.0	-3.3	3.2	-0.1	3.5	2.9	2.3	1.6	-2.1
Ever depressed for a whole week	0.8	0.9	4.3	1.1	0.3	1.2	-0.5	0.3	0.8	-0.2	0.6	-2.1
Unable to work because of sickness or disability	0.4	0.6	1.3	-0.2	-0.8	0.9	-1.1	0.8	-0.0	-0.6	1.1	0.0
Commuting to job workplace: Cycle	0.2	0.3	1.0	-0.2	-0.0	-0.5	0.6	-0.0	-0.3	0.4	-1.0	0.7
Myopia	2.0	2.9	5.4	1.5	-2.2	2.2	-1.9	2.3	1.6	1.1	-0.0	-1.3
Vascular/heart problems diagnosed by doctor	1.9	5.2	9.8	-2.3	2.5	-3.0	0.5	-2.7	-2.8	-3.1	-1.2	0.4
Cholesterol lowering medication	0.8	1.2	2.6	1.2	-1.0	1.5	-0.3	1.5	1.6	0.5	0.8	0.4
Medication: Omeprazole (e.g. Zanprol)	0.4	0.5	1.6	0.2	1.2	0.4	0.7	-1.1	-0.2	0.2	0.8	0.6
Pain experienced in last month	0.8	1.3	4.1	0.4	1.3	-1.3	0.6	-1.2	0.1	-0.7	-2.0	-1.3
Supplements: Calcium	0.4	0.4	1.5	0.3	1.0	-0.2	0.2	-0.9	0.0	0.6	-0.0	1.2
Basal cell carcinoma (self-reported)	1.4	1.7	3.7	0.5	-1.5	1.3	-1.9	1.4	0.8	0.5	1.5	-1.4
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.1	0.6	-0.9	0.2	-0.8	0.9	0.7	-0.1	0.5	1.1
Deep venous thrombosis (DVT) (self-reported)	0.8	1.0	3.7	-0.1	-1.7	0.2	-1.9	1.4	0.2	-0.5	0.5	0.2
Heart disease (siblings)	0.9	1.0	2.7	0.7	-1.7	0.8	-0.8	1.6	0.7	0.9	0.4	-1.0
Alcohol drinker status: Previous	0.3	0.4	1.0	0.2	-0.3	0.8	-1.0	0.4	0.4	0.8	-0.9	-0.3
Pack years of smoking	0.5	0.8	2.9	0.1	-0.6	1.7	-0.1	1.1	0.5	1.2	0.5	0.8
Impedance of whole body	5.7	29.2	65.8	-4.4	7.2	-7.1	1.1	-8.1	-5.8	-3.6	-4.2	3.2
Leg fat mass (left)	0.4	1.6	4.3	-0.8	-0.6	1.2	-1.8	0.7	-0.5	-1.8	2.1	0.7
Arm predicted mass (left)	0.4	2.2	7.6	-0.8	-2.8	1.2	-1.5	2.5	-0.2	-1.0	0.4	0.8