Hub : Genes

PSTPIP1

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 GTEx Adipose Subcutaneous 0.0700 0.0320 9.9e-04 0.054 NA 0.025 NA 0.033 3.1e-05 NA 3.9e-03 NA 1.0e-03
2 GTEx Brain Caudate basal ganglia 0.2160 0.0900 4.2e-04 0.124 NA 0.131 NA 0.131 2.1e-04 NA 1.4e-04 NA 1.4e-04
3 GTEx Cells EBV-transformed lymphocytes 0.1260 0.0540 5.4e-04 0.042 NA 0.099 NA 0.089 1.7e-02 NA 4.0e-04 NA 7.8e-04
4 GTEx Lung 0.0534 0.0292 9.1e-03 0.004 NA 0.004 NA 0.000 1.5e-01 NA 1.5e-01 NA 3.3e-01
5 GTEx Testis 0.0970 0.0600 6.7e-03 0.026 NA 0.009 NA 0.021 2.6e-02 NA 1.3e-01 NA 4.1e-02
6 METSIM Adipose 0.0402 0.0189 5.3e-05 0.045 0.029 0.023 0.032 0.037 2.4e-07 3.1e-05 1.7e-04 1.2e-05 2.3e-06
7 YFS Blood 0.3806 0.0646 0.0e+00 0.053 0.110 0.120 0.112 0.109 7.0e-17 3.9e-34 5.5e-37 1.2e-34 1.1e-33
8 TCGA Brain Lower Grade Glioma 0.0679 0.0293 2.9e-05 0.023 0.017 0.023 NA 0.024 1.0e-03 3.9e-03 1.0e-03 NA 8.9e-04
9 TCGA Thyroid Carcinoma 0.0730 0.0340 1.9e-03 0.015 0.024 0.031 NA 0.025 1.2e-02 2.1e-03 4.8e-04 NA 1.5e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9
Bipolar Disorder (2018) 0.2 0.3 0.8 0.9 -0.1 -0.8 0.7 0.2 0.4 -0.2 -0.0 -0.9
Bipolar Disorder or Schizophrenia 0.2 0.4 1.8 0.6 0.4 -1.3 0.0 -0.8 -0.3 -0.5 0.2 0.8
Depressed Affect (Nagel 2018) 0.4 0.8 2.6 -0.0 0.8 0.5 -1.6 -0.7 0.2 0.5 1.6 -0.6
Depression (Nagel 2018) 1.0 1.5 9.7 -0.9 -0.6 0.5 -3.1 0.2 -0.3 0.3 1.4 -0.2
Intelligence (Savage-Jansen 2018) 1.4 4.2 10.1 2.1 -3.1 2.3 -0.1 3.2 2.1 1.2 -0.1 -1.4
Neuroticism (Nagel 2018) 0.5 1.1 7.2 -0.3 -0.3 0.8 -2.7 0.1 0.1 0.7 1.2 0.2
Schizophrenia (2018) 0.5 0.9 4.5 0.1 0.7 -1.1 -0.7 -1.2 -0.6 -0.1 0.3 2.1
Schizophrenia vs Biploar Disorder 0.9 1.2 4.0 0.6 -2.0 0.8 -1.1 1.8 0.9 0.5 -0.0 -0.7
Worry (Nagel 2018) 0.3 0.7 4.6 -0.8 0.3 0.3 -2.1 -0.4 -0.5 0.1 0.1 0.4
Alzheimer’s Disease (in mother) 3.9 4.5 12.4 2.5 -1.5 2.4 0.3 2.4 2.6 0.7 3.5 0.8
Alzheimer’s Disease (in father) 1.7 1.8 5.2 1.8 -0.7 -0.1 2.3 1.1 1.6 1.6 -0.3 1.1
Alzheimer’s Disease (including proxy) 1.5 2.1 4.3 1.9 -1.1 1.3 0.8 1.5 2.0 0.6 2.1 1.1
Crohns Disease (2017) 4.0 8.7 19.5 -4.1 2.0 -3.8 -1.3 -3.0 -4.4 -1.7 -2.3 2.2
Irritable Bowel Disease (IBD) 2.6 6.2 13.7 -3.3 2.4 -3.0 0.1 -2.9 -3.7 -1.0 -1.2 2.5
Ulcerative Colitis (UC) 1.6 2.9 6.0 -1.5 2.4 -1.8 1.1 -2.4 -2.0 -0.6 -0.2 1.9
Major Depression (MDD) 0.9 1.1 2.0 -1.1 0.7 -0.7 -1.4 -1.2 -1.1 -1.2 -0.2 -1.1
Reaction Time 0.6 1.1 3.0 0.7 -0.9 1.6 -0.2 1.4 1.1 0.6 -0.0 -1.7
Verbal and Numeric Reasoning (VNR) 1.0 2.4 3.9 2.0 -1.3 1.9 0.5 1.7 1.8 2.0 -1.1 -1.1
Breast Cancer 1.3 3.1 5.6 -0.7 2.3 -2.3 2.1 -2.4 -1.2 0.1 -2.3 0.4
Ovarian Cancer 0.3 0.4 2.7 0.2 0.1 -0.4 0.4 0.1 -0.1 1.6 -0.7 0.6
Prostate Cancer 1.1 1.5 3.9 0.9 -2.0 1.0 -0.5 1.8 1.3 1.4 -0.3 -0.9
Age at First Birth 0.4 0.5 1.2 0.3 0.7 -1.0 0.6 -1.1 0.3 0.3 -0.7 -1.0
Bipolar Disorder (2011) 0.2 0.2 0.5 0.7 -0.2 0.7 -0.2 0.4 0.6 0.5 0.5 -0.2
Body Mass Index (BMI) (2010) 0.7 1.0 3.4 0.8 -0.1 1.8 -0.6 0.8 1.0 0.8 1.3 -0.3
Coronary Artery Disease (CAD) 2.8 3.3 12.9 1.9 -1.0 1.8 -1.7 1.2 2.1 0.8 3.6 -0.0
Crohns Disease (2012) 2.1 3.4 8.4 -2.6 1.0 -2.1 -0.6 -1.5 -2.9 -1.7 -1.7 1.4
Mean Putamen Volume 0.3 0.3 2.0 0.6 0.3 0.4 0.2 -0.2 0.2 1.4 0.2 0.1
Fasting Glucose 1.5 1.8 6.0 0.8 -1.1 2.4 -1.3 1.2 1.3 0.2 0.8 -1.5
HbA1C 5.4 6.0 12.7 2.9 -0.9 3.6 1.0 1.8 3.3 3.1 2.7 0.4
HDL Cholesterol 0.2 0.4 1.3 -0.7 -0.6 -0.4 0.1 0.6 -0.6 -0.3 0.6 1.1
LDL Cholesterol 0.3 0.5 1.3 1.0 0.0 1.0 0.1 0.1 1.0 0.3 1.1 0.4
Lupus 3.1 4.6 9.0 -2.6 1.3 -2.7 -1.3 -1.7 -3.0 -2.6 -2.2 1.0
Neuroticism (2016) 0.9 1.4 8.9 0.2 -0.7 0.6 -3.0 0.5 0.5 -0.2 1.4 0.2
Primary Biliary Cirrhosis 0.9 1.2 1.8 -1.4 0.9 -1.1 -0.9 -1.0 -1.4 -1.3 -1.0 -1.1
Rheumatoid Arthritis 4.9 6.8 15.4 -3.3 0.0 -2.7 -1.9 -1.1 -3.4 -3.9 -3.2 -0.7
Schizophrenia (2014) 0.6 1.2 3.2 0.6 -1.8 0.3 -1.7 1.7 0.4 0.6 1.1 0.3
Triglycerides 0.3 0.6 2.4 0.6 0.2 0.6 0.1 -0.0 0.6 1.1 -0.6 -1.5
Type 2 Diabetes (T2D) (2012) 2.0 2.3 8.3 0.6 -1.1 2.9 -0.0 1.5 1.1 1.3 2.2 -0.9
Ulcerative Colitis 0.4 0.5 1.9 -1.4 -0.1 -0.5 -0.2 0.1 -1.3 -0.7 0.3 -0.3
Blood Eosinophil Count 1.5 11.3 21.3 1.5 -4.3 4.6 -1.6 4.5 2.8 3.2 0.7 -4.3
Blood Platelet Count 0.6 6.6 12.0 3.5 3.1 1.5 2.5 -2.2 2.5 1.1 3.0 2.9
Blood Red Count 2.2 20.8 41.5 3.5 -6.0 6.4 -3.6 5.6 5.1 4.1 3.3 -0.8
Blood White Count 2.8 21.0 45.4 4.7 -3.9 6.7 -1.4 4.8 5.7 3.1 6.1 -1.5
Heel T-Score 1.1 8.9 26.3 -5.1 1.8 -3.5 -1.4 -2.7 -4.9 -1.6 -1.5 0.5
BMI 1.6 9.3 21.7 1.9 -3.0 4.7 -1.8 3.8 3.0 0.6 4.6 -0.7
Height 5.3 101.4 196.0 -10.4 8.7 -14.0 2.2 -11.5 -12.6 -8.8 -9.8 8.1
Waist Hip Ratio (WHR) 0.2 1.0 2.6 0.8 1.1 0.0 1.5 -1.1 0.5 0.4 -0.6 1.6
Systolic Blood Pressure 0.4 1.8 5.4 0.4 -2.2 0.9 -0.6 1.5 0.7 0.7 -1.0 -2.3
Smoking Status 0.8 1.9 5.0 2.2 0.9 0.6 1.7 -0.1 1.9 1.9 -0.3 0.4
Allergy or Eczema 1.1 2.8 6.9 -0.4 1.9 -2.2 0.9 -2.6 -0.9 -0.6 -2.5 -1.1
Cardiovascular Disease 2.4 7.9 16.7 3.4 -2.0 4.1 -0.1 2.6 3.9 3.2 2.4 0.5
Hypothyroidism (self reported) 0.2 0.5 1.4 -0.4 -0.7 0.1 0.8 1.2 -0.7 0.6 -1.0 0.6
Respiratory disease 1.9 4.1 9.5 -1.4 2.0 -2.2 -0.2 -2.2 -2.1 -2.0 -3.1 -1.8
Type 2 Diabetes (T2D) (2018) 3.2 6.1 15.3 0.9 -3.4 3.9 -2.7 2.9 2.3 0.8 1.9 -1.2
Lung FEV1/FVC ratio 13.4 67.9 139.2 7.0 -9.9 10.1 -3.9 11.8 9.3 4.0 8.3 -6.0
Lung FVC 1.1 5.8 16.2 1.5 3.2 -1.8 4.0 -2.7 0.2 0.7 -2.7 2.2
Neuroticism 0.7 1.6 8.9 -1.0 -0.6 0.6 -3.0 0.2 -0.5 0.4 1.5 -0.9
Chronotype (morning person) 0.3 0.7 1.7 -1.0 1.3 -0.4 -1.1 -1.1 -0.9 -0.4 -0.5 -0.3
Hair Pigment 0.3 9.2 20.5 -4.0 1.2 -4.2 -0.2 -2.6 -4.5 -2.6 -3.0 2.1
Tanning 0.1 0.8 1.6 0.4 1.0 -1.1 0.4 -0.7 -0.2 -1.1 1.0 1.3
Hand grip strength (left) 1.4 3.6 10.3 -2.0 -1.6 -2.9 -0.8 0.6 -2.1 -3.2 -0.1 1.3
Number of treatments/medications taken 1.3 2.3 5.4 1.2 -2.3 1.8 -0.6 2.2 1.4 0.4 0.4 -1.7
Average weekly spirits intake 3.1 3.8 8.4 -0.6 2.3 -2.3 1.1 -2.9 -1.5 -2.7 -1.7 1.1
Sensitivity / hurt feelings 0.8 1.4 5.4 -0.5 -2.3 0.7 -1.8 1.7 -0.1 -0.3 0.4 -0.2
Frequency of depressed mood in last 2 weeks 0.9 1.2 6.4 -1.2 -0.6 0.4 -2.5 0.3 -0.8 -0.1 1.2 -0.6
Hearing difficulty/problems: Yes 0.2 0.3 1.1 0.4 0.5 0.3 0.2 0.1 0.3 -0.6 1.0 0.8
Relative age of first facial hair 1.1 2.2 6.4 2.5 -0.4 0.9 1.3 1.0 2.3 1.9 0.6 -0.7
Other serious medical condition/disability diagnosed by doctor 1.0 1.3 4.7 2.2 0.8 0.3 1.4 -0.1 1.3 0.2 1.3 1.0
Ever used hormone-replacement therapy (HRT) 0.9 1.1 3.3 0.5 -1.0 1.2 0.7 1.2 0.2 1.8 -1.2 -0.9
Ever had hysterectomy (womb removed) 0.4 0.4 1.3 -0.0 1.1 0.5 0.2 -1.0 -0.3 -0.1 1.0 -0.1
Systolic blood pressure, automated reading 0.4 1.2 3.5 -0.4 -1.7 0.4 -1.4 1.3 0.1 -0.8 0.5 -1.9
Eye problems/disorders: Diabetes related eye disease 1.0 1.1 4.7 -0.1 -0.9 1.5 -0.0 0.8 0.2 1.0 0.2 -2.2
Angina 0.2 0.3 1.0 0.5 0.3 0.1 -0.6 -0.5 0.2 -0.3 1.0 0.6
Medication for hormone replacement therapy 1.5 1.7 3.7 0.7 -1.6 1.8 0.1 1.8 0.7 1.9 -0.1 -1.0
Vitamin and mineral supplements 1.1 1.5 4.9 -1.6 0.6 -1.1 -0.5 -0.5 -1.7 -2.2 -1.0 0.1
Supplements: Zinc 1.7 1.9 5.0 0.5 -2.2 1.6 -1.4 2.2 1.0 1.0 0.5 -0.8
Medication: Co-codamol 0.9 1.0 2.1 -1.1 1.2 -0.7 0.4 -1.2 -1.1 -0.5 0.9 1.4
Medication: Metformin 1.6 2.2 8.2 1.0 -1.4 2.9 -0.5 1.5 1.7 1.3 1.1 -0.7
Diabetes (father) 0.9 1.1 3.7 0.1 -1.4 1.1 -1.9 1.1 0.6 -0.6 0.5 0.9
Diabetes (mother) 1.6 2.1 7.5 0.1 -0.6 2.6 -0.7 0.6 0.9 0.9 2.7 -1.4
Severe depression (siblings) 0.4 0.5 1.9 -1.1 -0.1 -0.1 -0.1 -0.0 -1.4 0.1 -0.7 0.7
Pack years adult smoking proportion 0.7 1.0 3.7 0.1 -0.8 1.9 -0.3 1.4 0.6 1.3 0.7 0.6
Impedance of leg (right) 4.9 23.9 50.8 -5.1 6.0 -5.9 -0.2 -7.1 -5.8 -3.9 -2.7 3.2
Leg fat-free mass (left) 0.2 1.2 4.4 -0.1 -2.1 0.6 -0.4 1.9 0.0 -0.8 0.3 1.1
Trunk fat percentage 0.7 2.7 5.8 -1.6 1.8 -0.9 -1.2 -1.5 -2.0 -2.4 0.7 1.9
Hand grip strength (right) 1.6 4.5 10.8 -2.9 -1.8 -3.3 -1.2 0.4 -2.6 -2.7 -0.7 1.4
Townsend deprivation index at recruitment 1.0 1.4 4.5 0.8 -0.4 2.1 -1.1 0.7 1.2 0.6 1.6 -1.0
Current tobacco smoking 1.1 1.9 3.4 1.5 0.1 1.9 0.6 0.7 1.6 1.8 1.5 1.7
Average weekly fortified wine intake 1.7 2.0 6.3 -2.5 0.3 -1.5 0.5 -1.0 -2.5 -1.0 -1.1 -0.1
Maternal smoking around birth 1.2 1.7 3.5 0.5 -1.5 1.7 0.1 1.7 0.7 0.9 1.9 1.4
Fed-up feelings 0.3 0.5 2.9 -0.2 -0.4 0.7 -1.7 0.5 0.1 0.3 0.7 -0.3
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.3 8.1 -1.0 -1.2 0.5 -2.9 0.5 -0.3 -0.2 0.5 -0.1
Relative age voice broke 0.4 0.7 2.6 0.7 -0.1 0.9 0.8 0.6 0.8 1.6 0.3 -0.6
Taking other prescription medications 0.5 0.7 5.0 -0.5 -0.4 -0.0 -0.8 0.2 -0.6 -2.2 0.3 0.4
Age when periods started (menarche) 1.5 3.6 10.8 -1.7 1.8 -3.3 0.3 -2.5 -1.9 -1.5 -1.5 0.9
Bilateral oophorectomy (both ovaries removed) 0.1 0.1 0.3 -0.1 0.5 0.4 0.6 -0.1 -0.3 -0.1 -0.0 -0.3
Heel bone mineral density (BMD) T-score, automated (left) 0.8 1.9 4.1 -2.0 1.0 -1.5 -0.6 -1.4 -2.0 -0.2 -1.5 1.0
Tinnitus: Yes, but not now, but have in the past 0.2 0.2 0.8 0.3 0.1 0.4 0.2 -0.2 0.3 0.9 -0.3 0.7
Qualifications: CSEs or equivalent 1.1 1.4 4.7 -0.2 -1.3 1.3 0.1 1.3 0.5 0.4 2.2 1.6
Serious illness, injury or assault to yourself 0.2 0.2 0.6 0.4 0.6 0.8 0.7 -0.1 0.1 -0.3 0.2 0.5
High blood pressure 2.4 6.8 12.7 2.9 -2.8 3.4 -0.1 3.2 3.2 3.6 0.7 -0.1
Hayfever, allergic rhinitis or eczema 0.3 0.7 1.9 0.3 0.9 -0.9 0.9 -1.4 0.2 0.1 -1.2 -0.9
Multivitamins +/- minerals 1.3 1.7 5.0 1.6 -0.4 1.5 0.4 0.4 1.7 2.2 1.1 -0.6
Stomach or abdominal pain in last month 0.7 0.8 4.9 -0.4 -0.3 -0.0 -0.1 0.2 -0.0 0.5 1.5 2.2
Supplements: Glucosamine 0.5 0.6 1.5 0.6 1.2 -0.8 0.4 -1.1 0.1 0.4 -1.2 0.3
Diverticular disease/diverticulitis (self-reported) 0.8 0.9 3.2 -0.8 0.6 -0.1 -1.4 -0.6 -0.6 -1.8 0.9 -0.6
Medication: Atenolol 0.5 0.7 1.7 0.9 -1.3 0.8 -0.8 0.8 1.0 0.3 0.2 -0.8
Medication: Levothyroxine sodium 0.9 1.5 3.9 1.2 1.0 1.0 2.0 0.2 0.9 1.6 0.2 1.6
Sitting height 0.3 2.1 8.6 -0.2 -0.3 -1.2 1.8 0.1 -0.5 1.1 -1.9 2.9
Chronic bronchitis/emphysema (father) 0.2 0.2 1.0 0.1 0.3 0.6 -1.0 -0.4 -0.0 -0.5 0.6 -0.1
High blood pressure (mother) 2.8 3.9 9.2 2.0 -1.1 3.0 0.1 1.2 2.8 1.1 2.2 -2.2
Body mass index (BMI) 1.7 7.2 18.4 1.6 -2.7 4.3 -1.7 3.6 2.3 0.6 3.7 -0.9
Impedance of leg (left) 5.4 26.1 53.7 -5.4 6.1 -6.4 -0.4 -7.3 -6.1 -4.1 -3.5 2.7
Leg predicted mass (left) 0.2 1.1 4.1 0.0 -2.0 0.6 -0.3 1.9 0.1 -0.8 0.3 1.1
Trunk fat mass 0.5 2.2 5.5 -1.6 1.1 -0.7 -1.2 -1.0 -1.9 -2.3 0.6 2.0
Waist circumference 0.2 0.9 2.4 0.2 -0.5 1.6 -0.9 0.8 0.4 -0.7 1.5 1.1
Number of incorrect matches in round 1.5 2.5 6.3 1.4 -1.4 1.7 0.4 1.8 1.3 2.5 -0.6 -2.1
Past tobacco smoking 1.8 3.3 8.5 -1.3 -1.9 2.1 -2.5 1.6 -0.1 -1.3 2.9 -1.1
Alcohol usually taken with meals 0.3 0.5 2.8 -0.4 0.4 -1.0 0.1 -0.3 -0.2 -0.4 -1.7 -0.6
Nervous feelings 0.3 0.6 2.8 -1.0 -0.1 -0.5 -1.7 -0.2 -0.7 -0.7 -0.1 0.2
Frequency of tenseness / restlessness in last 2 weeks 0.8 1.2 3.1 0.3 -1.1 1.8 -1.1 0.9 0.8 1.5 0.6 -1.1
Hearing difficulty/problems with background noise 0.3 0.5 1.3 0.2 -0.5 1.0 -0.7 0.6 0.2 0.8 1.1 -0.5
Hair/balding pattern: Pattern 2 2.1 2.7 7.4 1.3 2.7 -0.7 2.4 -2.0 0.3 1.2 -1.6 0.9
Had menopause 1.3 1.6 5.0 1.7 -0.6 1.7 0.6 1.1 1.4 2.2 -0.1 -0.3
Had other major operations 0.9 1.1 4.2 1.1 -0.3 1.0 -0.2 1.1 1.2 0.2 2.0 0.6
Forced vital capacity (FVC) 3.4 13.2 27.0 -1.5 4.0 -5.2 3.7 -4.7 -2.7 -1.9 -3.8 3.5
Heel bone mineral density (BMD) T-score, automated (right) 2.6 5.9 13.2 -3.4 1.6 -2.9 -1.0 -2.2 -3.6 -1.8 -2.0 2.0
Ever unenthusiastic/disinterested for a whole week 0.5 0.6 2.2 -0.3 -0.5 -0.1 -0.2 0.2 -0.5 -1.2 -1.5 -1.0
Qualifications: None of the above 1.0 2.1 5.1 -0.5 2.0 -0.1 -0.9 -1.5 -0.7 -1.3 2.3 2.1
Financial difficulties in last 2 years 1.5 2.0 5.8 -0.7 -1.2 1.6 -2.4 0.9 -0.2 -1.3 2.2 -0.6
Mouth/teeth dental problems 1.5 2.4 5.8 1.4 -2.3 1.6 -0.0 2.4 1.8 0.5 -0.4 -1.4
Heart attack 0.4 0.6 1.2 0.7 -1.1 0.2 -0.7 1.0 0.7 -0.2 0.1 1.1
Allergy 0.3 0.7 2.7 0.4 -0.1 1.1 0.1 0.7 0.5 0.5 1.6 0.9
Pain all over the body in last month 0.5 0.5 2.5 -0.7 0.3 -0.2 0.1 -0.5 -0.7 -0.9 -1.6 0.1
Diabetes (self-reported) 1.8 2.9 7.1 0.4 -2.7 2.6 -1.7 2.2 1.3 0.1 1.3 -0.8
Hayfever/allergic rhinitis (self-reported) 4.7 6.3 14.9 -2.5 2.4 -3.9 0.7 -3.5 -3.0 -1.5 -2.3 0.0
Medication: Ramipril 0.4 0.6 3.3 -0.3 -0.9 -0.3 -0.2 0.4 -0.4 -0.4 -1.8 0.4
Medication: Simvastatin 0.8 1.2 2.2 1.4 0.4 1.2 0.7 -0.0 1.5 1.0 1.2 1.4
Fluid intelligence score 1.7 3.6 5.7 2.3 -1.9 2.4 -0.0 2.2 2.3 2.2 -1.0 -1.3
Illnesses of siblings 2.2 3.1 6.6 -0.8 1.8 -2.3 2.1 -1.7 -1.2 -0.1 -2.6 1.9
Neuroticism score 1.6 3.2 14.8 -1.6 -2.0 1.1 -3.8 1.5 -0.7 0.2 1.4 -1.3
Weight 0.2 1.2 3.2 -1.1 -0.6 0.3 -1.1 0.6 -1.0 -1.6 0.7 1.8
Impedance of arm (right) 4.3 19.9 49.6 -2.7 6.5 -5.9 1.6 -7.0 -4.3 -2.6 -3.2 2.7
Arm fat percentage (right) 0.5 2.0 9.0 0.6 -0.3 2.2 -1.2 1.1 0.7 -0.6 3.0 -0.1
Trunk fat-free mass 0.3 1.5 5.4 -1.0 -2.3 0.1 -0.7 1.8 -0.7 -1.0 -0.1 1.2
Hip circumference 0.4 1.5 4.5 -1.7 0.3 -0.1 -1.2 -0.1 -1.5 -2.1 0.7 1.4
Time employed in main current job 0.3 0.4 2.1 0.0 0.7 0.0 0.2 -0.5 -0.0 0.4 0.5 -1.4
Alcohol intake versus 10 years previously 1.5 2.2 6.8 -2.0 0.0 -1.4 -0.2 -0.1 -2.6 -1.9 -0.0 1.9
Father’s age at death 0.8 1.1 4.1 -0.1 1.0 -1.6 0.9 -1.0 -0.3 0.5 -2.0 -0.3
Worrier / anxious feelings 0.5 1.0 2.4 -1.3 -0.1 -0.8 -1.6 -0.6 -1.2 0.2 -1.5 0.3
Frequency of tiredness / lethargy in last 2 weeks 0.4 0.6 1.2 -0.8 0.8 0.3 -0.7 -1.1 -0.9 -0.3 0.8 0.7
Falls in the last year 0.3 0.4 1.0 1.0 -0.5 0.6 -0.3 0.5 0.9 0.7 0.1 -0.6
Hair/balding pattern: Pattern 3 0.3 0.5 1.2 -1.1 -0.9 -0.7 -0.1 0.5 -0.8 -0.4 -0.9 -0.1
Number of live births 0.3 0.4 1.1 -1.1 0.2 -0.1 -0.4 0.0 -0.9 0.4 0.9 0.3
Forced expiratory volume in 1-second (FEV1) 0.8 2.8 6.8 -0.2 1.5 -2.6 2.3 -1.8 -0.8 -1.4 -1.4 1.8
Pulse rate 0.9 1.6 3.6 0.6 -0.9 1.9 -0.6 1.6 0.9 -0.1 1.9 -1.4
Happiness 0.4 0.5 1.5 -0.3 -0.5 0.6 -1.2 0.0 -0.2 1.0 -1.2 -0.4
Noisy workplace 1.5 1.8 6.4 -0.0 2.5 -0.8 1.6 -1.7 -0.7 -0.3 0.4 1.7
Qualifications: A levels/AS levels or equivalent 0.7 1.5 6.5 -0.6 0.2 -1.8 0.4 -0.6 -1.1 -1.0 -2.5 -0.7
Serious illness, injury or assault of a close relative in last 2 years 2.2 2.5 4.8 2.2 0.8 1.9 1.4 0.2 2.2 2.1 1.7 0.4
Mouth/teeth dental problems: Dentures 1.8 3.0 4.9 -2.0 2.0 -2.0 -1.7 -1.8 -2.2 -1.7 0.9 0.8
Asthma 2.1 4.0 5.8 -2.3 0.4 -2.1 -1.8 -1.1 -2.4 -2.2 -2.4 -2.4
Medication: Ibuprofen (e.g. Nurofen) 1.5 1.9 4.7 -0.0 -1.9 1.4 -1.0 2.2 0.7 0.1 1.0 -2.0
Medication: Cholesterol lowering 0.7 1.0 2.1 1.3 0.1 1.4 0.9 0.2 1.3 1.1 1.3 0.3
Depression (self-reported) 0.3 0.3 1.2 -0.3 0.2 -0.7 -0.7 -0.6 -0.5 -1.1 0.1 0.1
Medication: Lansoprazole 0.9 1.1 2.6 1.0 -1.1 1.6 -0.4 1.3 1.2 1.0 0.6 0.4
Prospective memory result 0.4 0.4 2.2 -0.5 0.3 0.6 -0.3 0.1 -0.1 0.7 0.5 -1.5
Lung cancer (father) 2.5 2.9 11.3 0.4 0.2 2.3 1.3 0.5 0.9 2.2 3.4 1.4
Illnesses of mother 5.5 6.8 16.4 -2.7 2.1 -4.0 -0.1 -2.1 -3.5 -2.4 -2.6 2.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.8 7.1 -0.5 1.2 -2.7 2.2 -1.3 -1.1 -1.4 -2.3 1.1
Pulse wave Arterial Stiffness index 1.7 2.0 4.8 2.2 0.1 1.5 0.8 0.7 2.1 1.5 1.0 1.5
Impedance of arm (left) 5.9 27.3 61.6 -3.6 7.0 -7.1 2.2 -7.8 -5.3 -2.9 -4.6 3.0
Arm fat mass (right) 0.4 1.6 5.1 -0.0 -0.9 1.8 -1.4 1.3 0.2 -1.2 2.3 0.3
Trunk predicted mass 0.3 1.4 5.5 -0.9 -2.3 0.1 -0.7 1.8 -0.6 -1.0 -0.2 1.1
Standing height 3.7 36.3 73.2 -6.0 4.5 -8.6 1.0 -6.4 -7.4 -5.1 -6.4 5.7
Length of working week for main job 2.1 2.3 4.6 -2.1 0.8 -1.2 -1.5 -1.4 -2.0 -2.0 -1.5 -0.3
Exposure to tobacco smoke at home 0.3 0.4 2.1 -0.4 0.3 -0.2 -0.0 -0.5 -0.3 -0.2 -1.4 0.7
Breastfed as a baby 3.2 4.0 13.8 0.8 1.7 -1.1 3.5 -1.0 -0.2 1.6 -1.4 3.7
Tense / ‘highly strung’ 0.4 0.6 3.6 -0.1 -0.9 0.7 -1.9 0.7 0.1 -0.4 -0.5 -0.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.7 1.1 4.4 -0.0 -1.5 0.4 -2.1 0.6 0.5 -0.4 1.2 -0.8
Hair/balding pattern: Pattern 4 0.5 1.3 3.3 -1.2 -1.8 -0.1 -1.7 1.3 -0.7 -0.8 -0.0 -1.0
Birth weight of first child 0.4 0.8 2.3 0.5 -1.4 0.6 -1.3 1.5 0.5 0.1 -0.6 -0.4
Peak expiratory flow (PEF) 0.4 1.0 3.7 0.4 -1.1 -0.5 -0.6 0.9 0.5 -1.5 1.9 -0.3
Pulse wave reflection index 0.5 0.6 1.2 0.8 0.7 0.2 1.1 -0.5 0.5 0.9 -1.0 0.9
Ever highly irritable/argumentative for 2 days 0.3 0.3 0.8 -0.5 -0.4 0.5 -0.9 0.1 -0.7 -0.9 -0.1 -0.5
Loud music exposure frequency 0.3 0.3 1.8 0.5 -0.1 -0.2 0.2 -0.0 0.1 0.4 -1.3 -0.6
Qualifications: O levels/GCSEs or equivalent 0.9 1.5 5.4 0.2 1.2 -1.1 1.8 -1.4 -0.2 0.1 -2.3 0.4
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 3.0 -0.4 1.5 -0.7 1.7 -1.6 -0.6 0.6 -1.4 1.0
Blood clot in the leg (DVT) 0.7 0.9 3.4 -0.3 -1.5 0.1 -1.9 1.2 0.1 -0.6 0.3 -0.0
Medication: Paracetamol 0.6 1.0 3.9 -0.8 -0.5 1.0 -0.9 0.5 -0.4 0.6 2.0 -1.2
Headache pain in last month 1.3 2.2 10.6 -0.6 -1.1 1.9 -1.2 1.4 0.0 0.7 3.3 0.1
Medication for cholesterol, blood pressure or diabetes 1.1 1.8 4.2 -1.9 0.5 -2.0 -1.0 -0.9 -1.9 -1.3 -1.1 -0.7
Glaucoma (self-reported) 0.8 1.0 2.3 0.2 -1.0 0.1 -1.5 1.0 0.2 -1.0 1.0 -1.5
Gout (self-reported) 0.1 0.2 0.8 -0.5 0.1 0.5 0.5 0.1 -0.2 0.3 0.9 -0.1
Hypothyroidism/myxoedema (self-reported) 0.5 0.9 3.1 0.3 0.6 0.4 1.7 0.4 0.1 1.4 -0.4 1.5
Medication: Amlodipine 0.4 0.5 2.1 1.4 0.0 0.6 0.7 0.2 1.0 0.9 -0.1 -0.1
Medication: Ventolin 100micrograms inhaler 1.3 1.7 9.5 -0.0 -1.2 0.4 -1.9 0.4 0.1 -0.4 -0.2 -3.1
Birth weight 0.5 1.1 3.4 -1.1 0.4 -1.8 -0.0 -0.3 -1.1 -1.7 0.3 0.6
Chronic bronchitis/emphysema (mother) 0.9 1.0 3.8 -1.2 -0.6 0.6 -1.4 0.3 -0.8 -1.0 0.1 -1.9
High blood pressure (siblings) 1.4 2.0 3.8 1.0 -1.6 1.9 -0.9 1.5 1.4 0.0 1.7 -1.7
Forced vital capacity (FVC), Best measure 3.9 14.4 30.7 -2.3 3.7 -5.5 3.4 -4.4 -3.4 -2.2 -5.0 2.7
Body fat percentage 0.4 1.5 3.4 -1.2 0.8 0.4 -1.6 -0.5 -1.2 -1.8 1.7 1.1
Leg fat percentage (right) 0.6 2.0 7.9 -1.0 -0.0 1.5 -2.1 0.3 -0.7 -1.5 2.8 0.4
Arm fat-free mass (right) 0.5 2.4 8.5 -1.3 -2.9 0.5 -1.6 2.4 -0.7 -1.3 -0.1 0.8
Exposure to tobacco smoke outside home 1.0 1.3 3.9 -2.0 -0.5 0.2 -0.6 0.1 -1.4 -1.3 1.0 1.5
Comparative body size at age 10 1.0 2.7 8.4 0.7 2.4 -1.6 2.9 -2.0 0.0 -0.5 -0.8 1.5
Number of full brothers 2.1 2.7 7.0 -0.5 -2.4 1.6 -2.6 2.6 -0.1 0.5 1.4 -0.3
Worry too long after embarrassment 2.2 3.8 12.0 -1.2 -3.5 1.2 -3.0 2.7 -0.3 0.1 -0.1 -1.5
Seen a psychiatrist for nerves, anxiety, tension or depression 2.3 3.0 7.4 -0.6 2.5 -1.9 2.3 -2.7 -0.9 -0.2 -1.8 0.8
Wheeze or whistling in the chest in last year 0.6 1.1 2.1 -1.3 1.1 -0.8 -0.5 -1.2 -1.4 -0.4 -1.5 0.4
Number of children fathered 0.2 0.2 0.9 0.6 0.1 0.1 0.3 -0.5 0.3 -0.2 1.0 -0.4
Reason for reducing amount of alcohol drunk: Health precaution 0.8 0.9 4.9 -0.4 -0.6 -0.7 -0.6 0.3 -0.7 -0.6 -2.2 -1.1
Age at first live birth 1.5 2.6 8.0 0.1 1.4 -2.5 1.8 -1.7 -0.8 -0.5 -2.8 -0.4
Pulse wave peak to peak time 2.5 3.0 6.9 -2.6 -0.0 -2.1 -0.8 -0.9 -2.6 -1.9 -1.5 -1.2
Health satisfaction 0.6 0.7 4.0 0.5 0.0 2.0 -0.2 0.3 0.8 0.2 1.1 -0.8
Shortness of breath walking on level ground 0.3 0.4 1.2 -0.7 0.3 0.5 -1.1 -0.4 -0.8 -0.6 -0.3 -0.6
Qualifications: College or University degree 0.5 1.7 5.8 0.4 0.5 -0.4 1.9 -0.5 0.4 2.0 -2.4 -0.8
Eye problems/disorders: None of the above 1.1 1.3 4.0 -0.2 2.0 -0.5 1.0 -1.7 -0.6 -0.8 -0.8 1.3
Mouth/teeth dental problems: Loose teeth 0.7 0.9 1.7 1.3 1.0 -0.0 1.2 -1.0 0.7 0.8 0.2 1.1
Emphysema/chronic bronchitis 0.2 0.2 0.8 0.5 -0.1 0.4 0.9 0.4 0.3 0.4 -0.6 0.3
Medication for pain relief, constipation, heartburn 1.2 2.1 5.1 -0.9 1.2 -2.3 0.2 -1.7 -1.5 -1.0 -2.2 0.8
Neck or shoulder pain in last month 0.7 1.0 2.5 0.7 -1.0 1.4 -0.6 1.2 0.9 0.2 1.6 -0.8
Medication: Blood pressure 1.2 2.1 4.6 2.1 -1.3 1.9 0.5 1.4 1.8 1.6 0.2 0.8
Angina (self-reported) 0.3 0.4 1.5 0.8 0.3 0.4 -0.4 -0.3 0.6 -0.1 1.2 0.7
Migraine (self-reported) 0.1 0.1 0.4 0.1 0.2 0.4 0.2 -0.1 0.1 -0.6 0.7 0.1
Medication: Ibuprofen 1.3 1.6 3.5 0.2 -1.7 1.7 -0.7 1.9 0.8 1.0 0.8 -1.4
Medication: Allopurinol 0.2 0.3 1.4 0.1 0.1 0.5 0.8 0.5 0.1 1.2 0.2 -0.0
Medication: Omeprazole 0.3 0.4 1.3 -0.0 1.1 0.3 0.9 -0.9 -0.5 0.1 0.3 0.1
Medication: Seretide 50 evohaler 0.6 0.7 2.0 1.2 -0.3 0.5 0.3 0.8 0.8 1.4 -0.7 -0.7
Mean time to correctly identify matches 0.6 1.1 2.6 1.1 -0.4 1.6 -0.2 1.0 1.3 0.8 0.2 -1.6
Heart disease (mother) 0.1 0.1 0.5 0.2 0.7 0.2 -0.1 -0.7 0.2 0.1 -0.4 -0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.5 0.5 1.6 -0.5 0.5 -0.9 -0.8 -0.4 -0.4 -1.3 0.9 0.5
Whole body fat mass 0.3 1.4 3.9 -1.2 0.1 0.4 -1.6 -0.0 -1.2 -2.0 1.3 1.2
Leg fat mass (right) 0.4 1.6 4.7 -0.8 -0.4 1.2 -1.7 0.5 -0.5 -1.6 2.2 1.0
Arm predicted mass (right) 0.4 2.1 7.1 -1.4 -2.7 0.4 -1.4 2.1 -0.8 -1.3 -0.4 0.9
Pulse rate, automated reading 2.6 8.3 16.1 3.7 -1.4 3.8 1.6 2.9 4.0 3.0 2.8 0.0
Alcohol intake frequency. 1.3 3.0 12.6 -2.0 -1.0 1.6 -3.5 1.6 -1.2 -0.1 1.5 0.0
Comparative height size at age 10 2.9 15.7 28.5 -3.4 4.4 -5.0 1.4 -5.3 -4.4 -3.5 -4.0 2.7
Number of full sisters 2.0 2.4 8.0 -0.4 -1.6 2.3 -1.4 1.9 0.3 0.5 2.8 0.1
Suffer from ‘nerves’ 0.8 1.3 6.0 -1.7 0.5 -0.3 -2.5 -0.5 -1.1 -0.3 0.7 0.5
Overall health rating 0.6 1.3 6.8 0.8 0.3 1.2 -0.8 -0.0 0.7 -0.2 2.6 1.1
Chest pain or discomfort 0.2 0.2 0.6 0.1 0.8 0.4 0.5 -0.4 0.2 0.1 0.8 0.5
Had major operations 1.1 1.3 2.3 -1.1 0.8 -0.9 -0.5 -0.8 -1.5 -1.4 -1.0 1.5
Age at last live birth 1.2 1.8 4.6 -1.0 0.5 -2.2 0.1 -1.2 -1.5 -1.5 -1.8 0.7
Family relationship satisfaction 0.5 0.7 2.7 -0.3 0.5 0.5 -0.8 -0.6 -0.0 0.6 -1.6 -1.2
Leg pain on walking 0.6 0.8 3.2 0.1 -0.1 0.4 -1.7 0.5 0.1 0.4 1.8 -0.4
Qualifications: NVQ or HND or HNC or equivalent 1.1 1.3 3.1 -1.4 0.1 -1.2 0.7 -0.4 -1.8 -1.5 -1.4 0.4
Commuting to job workplace: Car/motor vehicle 1.3 1.5 4.3 -0.9 1.9 -0.5 1.1 -2.1 -1.3 0.0 0.7 1.2
Illness, injury, bereavement, stress in last 2 years 1.5 1.9 6.5 -1.5 -0.1 -2.6 -0.2 -0.6 -1.7 -0.8 -1.9 0.5
Medication: Aspirin 2.4 3.2 8.3 2.7 -1.4 1.8 -0.2 2.0 2.9 1.3 1.3 -0.5
Supplements: Vitamin C 0.3 0.3 1.1 0.7 -0.4 0.2 0.5 0.3 0.6 0.4 -0.4 1.0
Knee pain experienced in last month 0.3 0.5 1.4 -0.4 0.7 -0.6 -0.7 -0.9 -0.6 -0.2 0.1 1.2
Hypertension (Self-reported) 2.6 7.1 12.2 2.8 -3.0 3.5 -0.4 3.4 3.3 3.2 1.1 -0.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 0.9 2.2 0.7 1.1 1.3 0.0 -0.1 0.5 0.6 1.5 1.3
Illnesses of father: Heart disease 2.1 3.0 6.1 2.3 -0.1 1.8 2.4 0.6 2.2 2.5 0.7 -0.7
Illnesses of siblings: Diabetes 1.6 1.9 6.3 0.5 -0.8 2.5 -1.2 1.2 1.0 1.0 2.3 -0.4
Smoking status: Previous 1.2 1.8 6.8 0.8 0.8 -1.9 1.5 -0.8 -0.2 1.1 -2.6 0.0
Forced expiratory volume in 1-second (FEV1), predicted 0.8 1.6 3.0 0.1 1.7 -1.4 1.7 -1.6 -0.3 -1.1 -0.2 1.6
Whole body fat-free mass 0.3 1.5 6.1 -0.6 -2.5 0.4 -0.7 2.1 -0.3 -1.0 -0.0 1.0
Leg fat-free mass (right) 0.2 1.2 5.2 0.1 -2.3 0.5 -0.3 2.1 0.2 -0.6 -0.1 0.7
Arm fat percentage (left) 0.3 1.2 5.6 0.2 -0.2 1.7 -1.1 0.8 0.3 -0.8 2.4 -0.0
Average weekly red wine intake 1.2 1.8 6.9 0.2 -2.1 0.9 -0.8 1.5 0.8 0.5 0.1 -2.6
Handedness (chirality/laterality): Left-handed 0.3 0.3 1.3 -0.4 0.3 -0.5 -0.3 -0.8 -0.3 -0.5 -0.2 1.1
Mood swings 0.8 1.4 6.2 -0.2 -0.4 0.8 -2.5 0.2 0.3 -0.6 2.1 -0.4
Loneliness, isolation 0.4 0.6 2.6 -0.3 -0.3 0.5 -1.6 0.3 0.0 0.0 1.0 -1.1
Long-standing illness, disability or infirmity 1.3 1.9 5.3 1.1 -1.2 1.9 -1.3 1.6 1.2 -0.1 2.3 0.5
Ever had bowel cancer screening 1.5 1.7 5.0 -0.3 2.2 -0.8 0.8 -1.9 -0.8 -0.2 0.3 2.2
Diabetes diagnosed by doctor 2.0 3.3 9.3 0.5 -2.5 3.0 -1.9 2.0 1.5 0.2 1.8 -0.5
Ever had stillbirth, spontaneous miscarriage or termination 0.6 0.7 3.4 0.5 -0.8 0.8 -0.0 0.8 0.5 0.1 1.9 -0.1
Friendships satisfaction 0.7 0.8 3.0 -0.0 -0.3 1.5 -1.0 0.6 0.2 1.7 0.2 -0.9
Qualifications: nursing, teaching 1.8 2.7 12.2 1.0 1.3 -0.2 3.5 -0.9 0.5 2.0 -2.2 0.1
Commuting to job workplace: Walk 1.1 1.2 3.2 0.7 -1.4 0.8 0.6 1.5 1.0 1.8 -0.3 1.0
Eye problems/disorders: Cataract 0.7 0.8 2.1 -0.0 -1.4 -0.0 -0.4 1.4 0.1 1.2 0.1 -1.2
Mouth/teeth dental problems: Mouth ulcers 1.2 2.0 3.5 -1.5 1.7 -1.2 1.3 -1.9 -1.7 0.2 -0.0 1.8
Medication for cholesterol 2.1 3.2 7.0 -1.4 2.2 -2.5 0.1 -2.6 -1.8 -2.0 0.1 1.2
Medication: Laxatives (e.g. Dulcolax, Senokot) 2.3 2.7 6.6 -0.8 2.6 -1.3 0.7 -2.5 -1.2 -1.0 0.1 2.5
Back pain experienced in last month 0.3 0.4 1.5 -0.5 0.3 0.9 0.6 -0.0 -0.8 0.1 1.2 0.5
Mineral and other dietary supplements 0.4 0.5 1.9 -1.1 -0.4 0.1 -0.3 0.3 -0.8 -1.4 0.8 0.1
Breast cancer (self-reported) 0.6 0.8 1.8 0.8 -1.3 0.9 -0.8 1.3 0.9 -0.4 -0.1 -0.6
Asthma (self-reported) 1.9 3.8 5.7 -2.2 0.4 -2.1 -1.7 -1.0 -2.3 -2.2 -2.3 -2.4
Osteoporosis (self-reported) 1.3 1.6 3.8 0.1 1.9 -1.4 1.3 -1.9 -0.7 -1.0 -0.4 1.1
Osteoarthritis (self-reported) 0.9 1.2 4.1 0.6 2.0 -0.5 0.6 -2.0 -0.0 0.1 -0.7 1.0
Medication: Aspirin 2.3 3.0 8.3 2.9 -1.2 1.6 0.0 1.7 2.9 1.2 1.2 -0.5
Medication: Gliclazide 2.0 2.2 3.6 1.1 -1.9 1.6 -1.2 1.8 1.8 0.4 1.5 -1.5
Illnesses of father: None of the above (group 1) 1.4 1.7 3.8 -1.9 -0.1 -1.3 -1.9 -0.1 -1.6 -1.9 0.4 -0.1
Smoking status: Current 0.8 1.2 2.1 1.3 0.4 1.5 0.7 0.4 1.4 1.3 1.0 1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.6 1.8 0.3 1.1 -0.7 1.3 -0.9 0.2 -0.5 -0.5 0.1
Whole body water mass 0.3 1.5 6.4 -0.6 -2.5 0.5 -0.8 2.1 -0.3 -0.9 0.0 1.0
Leg predicted mass (right) 0.2 1.3 5.4 0.0 -2.3 0.5 -0.3 2.1 0.1 -0.6 -0.1 0.7
Arm fat mass (left) 0.3 1.2 3.7 -0.3 -0.5 1.4 -1.3 0.8 -0.2 -1.3 1.9 0.6
Number of self-reported non-cancer illnesses 1.2 2.1 6.6 0.3 -1.2 2.3 -1.5 1.5 0.7 0.3 2.6 0.2
Average weekly champagne plus white wine intake 2.2 3.0 7.1 -2.3 -0.9 -1.2 -1.7 0.1 -2.0 -2.0 -2.7 -1.1
Miserableness 0.4 0.7 1.2 -1.0 0.7 -0.5 -1.0 -1.0 -0.8 -0.3 1.1 0.6
Guilty feelings 0.6 0.8 2.8 -0.8 -0.1 -0.5 -1.7 -0.7 -0.8 0.0 1.6 0.5
Wears glasses or contact lenses 1.1 1.2 3.4 1.2 -0.4 -0.4 1.8 0.3 0.5 1.6 -1.7 0.1
Ever taken oral contraceptive pill 0.6 0.7 2.1 -0.4 -1.4 0.3 -0.1 1.3 -0.1 -0.2 1.3 0.6
Hearing aid user 0.3 0.3 1.8 -0.2 -0.1 0.1 0.2 0.2 0.1 -0.2 1.0 -1.3
Mother’s age at death 0.8 1.0 3.4 0.2 -0.3 -0.8 1.5 -0.0 0.1 1.3 -1.9 -0.7
Financial situation satisfaction 1.7 2.1 5.5 -1.2 -1.9 1.7 -1.8 1.2 -0.5 0.0 0.8 -2.3
Tinnitus: Yes, now most or all of the time 1.2 1.4 5.7 2.4 0.9 0.1 1.4 0.1 1.6 -0.4 0.4 1.1
Commuting to job workplace: Public transport 1.0 1.1 3.5 0.7 -1.5 0.0 -0.9 1.2 1.1 -0.5 0.3 -1.9
Eye problems/disorders: Glaucoma 0.5 0.6 2.3 -0.2 -0.9 -0.4 -1.5 0.6 -0.0 -1.2 0.3 -0.7
Medication: Blood pressure 2.3 4.3 8.3 1.7 -2.8 2.3 -0.7 2.9 2.3 2.4 0.2 -1.7
Pain type(s) experienced in last month: Hip pain 0.2 0.3 0.5 -0.3 0.5 -0.4 0.1 -0.6 -0.7 0.7 -0.2 0.6
Supplements: Fish oil (including cod liver oil) 1.4 1.8 5.1 2.3 -0.6 1.2 0.4 1.0 1.9 1.9 0.2 -0.9
High cholesterol (Self-reported) 1.3 2.3 4.1 1.7 -1.1 2.0 -0.1 1.6 2.0 0.7 1.9 1.4
Medication: Bendroflumethiazide 2.7 4.1 13.4 1.5 -3.7 1.8 0.4 3.4 1.6 1.8 0.4 -0.3
Medication: Paracetamol 0.9 1.4 3.1 -1.4 -0.9 0.7 -1.7 0.5 -0.9 0.2 1.4 -1.8
Medication: Lisinopril 1.9 2.5 5.4 2.3 0.0 1.8 1.3 0.9 2.0 2.1 1.7 -0.2
Medication: Atorvastatin 1.1 1.3 3.7 0.2 -1.6 1.4 -0.1 1.6 0.5 -0.6 1.9 -0.6
Illnesses of father: High blood pressure 0.5 0.6 2.1 0.4 -0.1 0.7 1.4 0.3 0.5 1.0 -0.7 -0.8
Alcohol drinker status: Never 2.3 2.7 8.7 -2.8 -0.5 -0.5 -3.0 -0.5 -2.1 -1.5 -0.4 -0.6
Ever smoked 2.6 4.6 10.3 0.6 2.8 -2.4 2.5 -2.4 -0.8 1.1 -3.2 2.0
Basal metabolic rate 0.2 1.3 3.7 -0.8 -1.9 0.2 -0.8 1.6 -0.6 -1.3 0.1 1.3
Leg fat percentage (left) 0.5 1.9 6.5 -0.9 -0.1 1.4 -2.2 0.4 -0.6 -1.5 2.5 -0.0
Arm fat-free mass (left) 0.4 2.1 7.1 -0.8 -2.7 1.0 -1.4 2.4 -0.2 -1.2 0.4 0.7
Number of operations (self-reported) 0.1 0.1 0.3 -0.0 -0.1 0.1 -0.2 0.5 -0.3 -0.6 -0.1 0.6
Average weekly beer plus cider intake 1.0 1.4 4.8 0.2 2.2 -0.4 0.6 -1.8 -0.2 1.6 1.0 0.9
Irritability 0.4 0.6 2.5 -0.2 -0.1 0.8 -1.6 -0.1 0.1 0.5 -0.6 -1.4
Risk taking 0.6 0.9 2.2 -1.5 0.7 -0.1 1.3 -0.9 -1.3 0.5 0.3 -0.9
Ever had prostate specific antigen (PSA) test 0.4 0.4 1.8 -0.3 -0.4 -0.5 -1.2 0.0 -0.2 -1.3 0.3 -0.2
Fractured/broken bones in last 5 years 1.5 1.9 7.3 -0.8 2.7 -1.4 0.9 -2.0 -1.1 -0.5 -0.6 -0.8
Age started oral contraceptive pill 1.9 2.4 4.4 -1.7 1.4 -2.1 -0.3 -1.7 -2.1 -1.2 -1.4 1.1
Diastolic blood pressure, automated reading 2.1 6.5 12.5 2.0 -3.3 3.2 -0.1 3.5 2.9 2.3 1.6 -2.1
Ever depressed for a whole week 0.8 0.9 4.3 1.1 0.3 1.2 -0.5 0.3 0.8 -0.2 0.6 -2.1
Unable to work because of sickness or disability 0.4 0.6 1.3 -0.2 -0.8 0.9 -1.1 0.8 -0.0 -0.6 1.1 0.0
Commuting to job workplace: Cycle 0.2 0.3 1.0 -0.2 -0.0 -0.5 0.6 -0.0 -0.3 0.4 -1.0 0.7
Myopia 2.0 2.9 5.4 1.5 -2.2 2.2 -1.9 2.3 1.6 1.1 -0.0 -1.3
Vascular/heart problems diagnosed by doctor 1.9 5.2 9.8 -2.3 2.5 -3.0 0.5 -2.7 -2.8 -3.1 -1.2 0.4
Cholesterol lowering medication 0.8 1.2 2.6 1.2 -1.0 1.5 -0.3 1.5 1.6 0.5 0.8 0.4
Medication: Omeprazole (e.g. Zanprol) 0.4 0.5 1.6 0.2 1.2 0.4 0.7 -1.1 -0.2 0.2 0.8 0.6
Pain experienced in last month 0.8 1.3 4.1 0.4 1.3 -1.3 0.6 -1.2 0.1 -0.7 -2.0 -1.3
Supplements: Calcium 0.4 0.4 1.5 0.3 1.0 -0.2 0.2 -0.9 0.0 0.6 -0.0 1.2
Basal cell carcinoma (self-reported) 1.4 1.7 3.7 0.5 -1.5 1.3 -1.9 1.4 0.8 0.5 1.5 -1.4
Heart attack/myocardial infarction (self-reported) 0.4 0.5 1.1 0.6 -0.9 0.2 -0.8 0.9 0.7 -0.1 0.5 1.1
Deep venous thrombosis (DVT) (self-reported) 0.8 1.0 3.7 -0.1 -1.7 0.2 -1.9 1.4 0.2 -0.5 0.5 0.2
Heart disease (siblings) 0.9 1.0 2.7 0.7 -1.7 0.8 -0.8 1.6 0.7 0.9 0.4 -1.0
Alcohol drinker status: Previous 0.3 0.4 1.0 0.2 -0.3 0.8 -1.0 0.4 0.4 0.8 -0.9 -0.3
Pack years of smoking 0.5 0.8 2.9 0.1 -0.6 1.7 -0.1 1.1 0.5 1.2 0.5 0.8
Impedance of whole body 5.7 29.2 65.8 -4.4 7.2 -7.1 1.1 -8.1 -5.8 -3.6 -4.2 3.2
Leg fat mass (left) 0.4 1.6 4.3 -0.8 -0.6 1.2 -1.8 0.7 -0.5 -1.8 2.1 0.7
Arm predicted mass (left) 0.4 2.2 7.6 -0.8 -2.8 1.2 -1.5 2.5 -0.2 -1.0 0.4 0.8