TWAS hub - HMG20A

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0590	0.0220	9.2e-06	0.031	0.044	0.059	0.046	0.053	1.1e-04	4.1e-06	9.8e-08	2.3e-06	4.9e-07
2	GTEx	Adipose Subcutaneous	0.1620	0.0460	1.7e-08	0.087	NA	0.064	NA	0.087	1.4e-07	NA	5.9e-06	NA	1.4e-07
3	GTEx	Artery Aorta	0.1770	0.0510	1.7e-07	0.104	NA	0.184	NA	0.174	2.4e-06	NA	2.1e-10	NA	7.3e-10
4	GTEx	Artery Coronary	0.4150	0.0920	1.4e-05	-0.007	NA	0.126	NA	0.039	6.6e-01	NA	5.1e-05	NA	1.9e-02
5	GTEx	Artery Tibial	0.1234	0.0403	4.5e-07	0.091	NA	0.074	NA	0.083	1.3e-07	NA	2.0e-06	NA	4.4e-07
6	GTEx	Brain Cerebellum	0.1400	0.0620	2.7e-03	0.026	NA	0.102	NA	0.066	5.7e-02	NA	6.4e-04	NA	5.2e-03
7	GTEx	Breast Mammary Tissue	0.1340	0.0580	5.9e-04	0.058	NA	0.032	NA	0.070	6.3e-04	NA	9.1e-03	NA	1.7e-04
8	GTEx	Breast Mammary Tissue (Male)	0.0590	0.0552	1.6e-01	0.054	NA	0.079	NA	0.072	2.2e-02	NA	6.9e-03	NA	9.8e-03
9	GTEx	Esophagus Gastroesophageal Junction	0.2780	0.0750	1.5e-07	0.228	NA	0.230	NA	0.267	9.6e-09	NA	8.2e-09	NA	3.6e-10
10	GTEx	Lung	0.1008	0.0415	1.0e-03	0.009	NA	-0.002	NA	0.016	5.8e-02	NA	4.6e-01	NA	2.0e-02
11	GTEx	Muscle Skeletal	0.0420	0.0210	4.6e-03	0.004	NA	0.005	NA	0.006	1.3e-01	NA	9.7e-02	NA	7.2e-02
12	GTEx	Nerve Tibial	0.1707	0.0534	1.5e-06	0.053	NA	0.078	NA	0.077	1.2e-04	NA	3.6e-06	NA	3.9e-06
13	GTEx	Pituitary	0.1230	0.0530	3.4e-03	0.125	NA	0.154	NA	0.145	4.9e-04	NA	1.1e-04	NA	1.8e-04
14	GTEx	Thyroid	0.0560	0.0240	1.8e-03	0.005	NA	0.053	NA	0.031	1.2e-01	NA	6.9e-05	NA	1.9e-03
15	GTEx	Vagina	0.2070	0.0840	2.6e-03	0.013	NA	0.054	NA	0.020	1.6e-01	NA	2.3e-02	NA	1.1e-01
16	METSIM	Adipose	0.0435	0.0200	2.0e-04	0.011	0.010	0.012	0.010	0.006	7.2e-03	8.9e-03	5.3e-03	9.6e-03	3.1e-02
17	TCGA	Rectum Adenocarcinoma	0.2210	0.1070	2.0e-03	0.175	0.066	0.084	NA	0.116	6.8e-05	1.2e-02	5.2e-03	NA	1.2e-03

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Type 2 Diabetes (T2D) (2018)	9.6	17.9	35.5	6.0	4.3	4.8	4.6	3.9	4.8	2.1	2.5	3.6	3.3	5.7	3.3	5.8	5.2	0.9	4.7	-2.4
Diabetes diagnosed by doctor	7.1	11.7	22.0	4.4	3.4	4.0	4.2	3.1	3.9	1.3	1.8	2.6	2.0	4.6	2.7	4.7	4.7	0.7	4.0	-2.0
Number of full brothers	7.0	8.8	14.7	3.8	3.7	3.6	2.3	3.4	3.4	2.8	2.7	3.4	3.5	2.2	3.0	3.1	2.8	2.1	2.5	0.4
Diabetes (self-reported)	6.0	9.3	17.5	3.9	3.1	3.8	3.7	2.7	3.8	1.4	1.7	2.4	2.0	4.1	2.4	4.2	4.2	0.8	3.0	-1.7
Worry too long after embarrassment	5.9	9.9	20.2	3.4	4.5	4.0	-0.2	4.3	4.5	3.1	2.9	4.0	3.2	-1.3	3.1	2.9	3.0	0.7	2.8	1.4
Medication: Metformin	5.4	7.6	20.5	3.7	2.4	2.9	3.8	2.1	2.8	0.2	0.8	1.8	1.4	4.5	1.7	3.8	3.7	-0.4	3.3	-2.6
Financial situation satisfaction	4.9	6.1	15.3	2.9	2.7	3.1	1.2	2.6	3.0	1.7	2.3	2.5	1.9	2.3	1.5	3.9	3.4	1.2	2.5	-0.7
Alcohol intake frequency.	4.6	10.6	29.3	3.8	3.7	2.8	1.6	3.8	3.1	2.4	2.9	3.7	3.6	1.7	3.6	3.6	3.9	1.5	5.4	0.9
Number of full sisters	4.6	5.6	11.4	3.4	2.2	2.2	2.7	2.4	2.6	1.3	1.8	2.3	2.9	2.4	2.6	2.9	2.6	1.4	2.4	-0.7
Medication: Paracetamol	4.5	7.0	12.7	2.9	3.1	2.9	2.2	3.3	1.9	2.3	2.6	3.4	3.3	0.6	3.6	2.6	2.8	0.7	3.2	1.0
Seen a psychiatrist for nerves, anxiety, tension or depression	4.3	5.5	9.7	-3.1	-2.7	-2.0	-1.2	-2.4	-2.9	-2.0	-1.7	-2.4	-2.9	-2.8	-2.1	-2.3	-2.4	-3.1	-2.1	-0.3
Tinnitus: Yes, now most or all of the time	4.2	4.9	10.7	-2.0	-2.0	-2.9	-1.3	-2.3	-1.6	-2.6	-3.1	-2.2	-1.8	-1.5	-0.7	-3.3	-3.1	-2.8	-1.2	-1.3
Alcohol drinker status: Never	4.2	5.0	8.9	1.7	2.4	2.8	1.3	2.9	1.7	2.6	3.0	2.6	1.9	1.0	1.8	3.0	2.1	1.3	2.7	1.6
Hair/balding pattern: Pattern 2	4.1	5.2	8.5	-1.9	-2.9	-2.1	-0.4	-2.6	-2.4	-2.9	-2.6	-2.9	-2.4	-1.3	-2.6	-2.3	-1.5	-2.9	-1.8	-1.8
Fasting Glucose	4.0	4.8	10.7	3.3	2.2	2.7	2.6	2.1	1.8	0.4	0.7	1.7	1.9	2.9	1.4	3.1	2.6	0.4	2.3	-2.1
Type 2 Diabetes (T2D) (2012)	3.8	4.4	13.6	2.9	1.4	2.2	2.3	1.4	2.4	0.8	1.2	1.1	1.1	3.7	0.5	3.3	3.4	1.0	1.1	-1.9
Leg fat percentage (right)	3.8	13.8	29.6	4.4	3.6	3.9	4.5	3.8	3.9	1.7	2.4	3.5	4.1	3.0	3.9	3.8	5.4	1.4	5.2	-0.9
Other serious medical condition/disability diagnosed by doctor	3.6	4.7	8.5	-1.6	-2.2	-2.0	-1.1	-2.6	-1.5	-2.6	-2.8	-2.5	-2.7	-0.5	-1.3	-2.3	-1.8	-2.9	-2.6	-1.9
Body mass index (BMI)	3.4	14.4	28.6	4.9	4.2	3.2	4.0	3.2	5.3	1.0	1.3	3.4	3.3	5.1	4.0	3.7	5.0	2.0	4.6	-2.5
Leg fat mass (right)	3.4	13.4	25.5	4.1	3.8	3.6	4.3	3.8	3.8	2.0	2.4	3.8	4.2	3.2	4.3	3.2	5.1	2.3	4.8	-0.5
Hand grip strength (right)	3.3	9.0	44.9	-1.4	2.0	1.0	-0.4	1.8	0.1	4.4	3.1	2.4	2.5	-1.3	3.9	-1.5	0.1	6.7	-0.3	6.1
Leg fat percentage (left)	3.3	12.0	27.1	4.0	3.3	3.6	4.3	3.5	3.7	1.6	2.2	3.3	3.8	2.9	3.5	3.5	5.2	1.5	4.9	-0.8
Leg fat mass (left)	3.3	13.0	25.3	4.0	3.8	3.5	4.2	3.7	3.8	2.0	2.4	3.8	4.2	3.0	4.3	3.1	5.0	2.5	4.8	-0.3
Neuroticism score	3.2	6.7	13.7	2.5	3.6	3.7	0.9	3.5	3.2	2.6	2.8	3.1	1.9	-1.4	2.3	3.4	2.8	-0.4	1.6	1.0
Impedance of arm (left)	3.1	14.1	48.0	-5.2	-5.2	-2.7	-1.6	-3.0	-6.9	-2.0	-1.3	-3.7	-2.2	-6.2	-4.2	-3.4	-3.0	-3.2	-1.9	2.1
Breastfed as a baby	3.1	3.8	8.4	-2.3	-1.9	-2.5	-2.3	-2.2	-1.9	-1.5	-1.9	-1.9	-1.7	-1.6	-1.2	-2.9	-2.2	-1.4	-1.9	-0.0
Financial difficulties in last 2 years	3.0	4.0	6.9	2.6	2.4	2.4	1.1	2.5	2.4	1.6	1.7	2.3	2.1	1.5	1.8	2.6	2.3	0.9	1.8	-0.1
Age when periods started (menarche)	2.9	7.0	24.4	-3.7	-2.2	-2.1	-1.9	-1.6	-3.7	0.2	-0.4	-1.3	-1.5	-4.9	-1.2	-3.0	-3.9	-0.5	-3.6	2.8
Illnesses of siblings: Diabetes	2.9	3.5	9.6	2.8	1.3	1.4	2.7	1.3	1.5	0.2	0.8	1.0	1.1	3.1	1.1	2.9	2.7	-0.6	1.8	-2.1
Impedance of arm (right)	2.8	13.1	44.0	-4.7	-5.0	-3.1	-1.2	-3.1	-6.6	-2.2	-1.6	-3.6	-2.1	-5.5	-3.8	-3.6	-3.4	-3.4	-2.0	1.6
Headache pain in last month	2.8	4.8	8.4	2.8	2.3	2.1	2.5	2.4	2.4	1.6	1.9	2.3	2.7	1.3	2.2	2.4	2.4	1.0	2.9	0.4
Bipolar Disorder (2018)	2.7	4.2	9.2	-2.4	-2.4	-2.3	-0.5	-2.4	-2.3	-1.2	-1.6	-2.2	-2.4	-1.4	-1.8	-2.3	-2.9	-0.8	-3.0	0.1
Hip circumference	2.7	11.7	26.7	3.4	3.5	3.1	2.7	3.7	2.8	2.4	2.8	3.8	4.5	2.4	4.3	2.8	4.6	2.8	5.2	0.7
Alcohol intake versus 10 years previously	2.7	4.0	14.7	1.4	1.8	1.7	1.3	2.3	0.5	2.0	2.1	2.2	2.5	-0.3	3.8	1.1	1.6	1.9	2.5	2.0
Medication: Lansoprazole	2.7	3.0	6.7	2.4	2.3	1.9	0.9	2.1	2.1	1.0	0.8	2.0	2.4	0.6	2.2	1.2	1.6	0.2	2.6	-0.2
Qualifications: nursing, teaching	2.7	4.2	8.2	-1.1	-2.1	-1.9	-2.2	-2.0	-1.9	-2.2	-1.8	-2.0	-2.4	2.6	-2.9	-0.2	-2.6	-2.0	-1.1	-2.3
Sensitivity / hurt feelings	2.6	4.5	8.8	2.2	3.0	2.8	0.5	2.7	2.8	2.1	2.0	2.5	1.9	-0.7	2.4	2.4	2.7	0.7	1.2	0.9
Length of working week for main job	2.6	2.9	9.7	1.4	1.1	2.5	-0.3	1.8	0.8	1.6	2.3	1.2	1.4	0.5	0.6	2.9	3.1	-0.1	2.2	0.2
Chronic bronchitis/emphysema (mother)	2.6	3.0	5.7	2.1	1.5	1.7	-0.2	1.8	1.8	1.5	1.9	1.8	2.2	2.1	1.0	2.4	2.0	1.0	2.2	0.2
Whole body fat mass	2.6	10.7	23.4	3.4	3.3	3.2	4.1	3.4	3.1	1.7	2.3	3.3	3.9	2.3	3.9	2.7	4.8	2.3	4.6	-0.1
Illnesses of father: Heart disease	2.6	3.5	7.4	-0.9	-1.5	-1.9	-0.0	-2.0	-0.7	-2.3	-2.4	-2.0	-2.5	0.4	-2.1	-1.3	-2.0	-2.4	-2.7	-2.1
Osteoporosis (self-reported)	2.6	3.3	8.3	-1.7	-2.9	-1.9	0.3	-2.2	-2.6	-1.9	-1.6	-2.4	-2.0	-0.4	-2.3	-1.2	-0.8	-1.1	-2.1	-0.7
Arm fat mass (right)	2.5	10.3	20.0	3.7	3.3	2.8	4.1	3.0	3.5	1.1	1.6	3.1	3.5	3.4	3.7	2.7	4.4	2.1	4.5	-1.2
Medication: Paracetamol	2.5	4.2	8.7	2.5	2.3	2.0	1.4	2.4	1.5	1.6	1.8	2.6	2.8	0.1	2.9	1.9	2.2	0.1	2.8	0.6
Arm fat mass (left)	2.5	10.1	21.4	3.5	3.2	2.8	4.1	3.1	3.3	1.1	1.6	3.0	3.5	3.1	3.6	2.7	4.6	2.0	4.6	-1.0
Arm fat-free mass (left)	2.5	12.6	22.0	3.6	4.5	3.1	2.1	3.9	4.2	3.4	3.1	4.4	3.9	3.0	4.7	2.6	3.6	4.1	3.1	1.2
Hand grip strength (left)	2.4	6.2	35.1	-1.5	1.0	-0.1	-0.5	0.8	-0.2	3.6	2.2	1.5	1.8	-0.1	3.1	-1.9	-1.1	5.9	-0.2	5.4
Maternal smoking around birth	2.4	3.4	9.2	2.8	1.9	1.4	1.7	1.5	2.6	1.0	1.1	1.9	2.1	3.0	2.1	1.6	2.0	1.0	1.0	-0.6
Body fat percentage	2.4	9.4	24.1	3.2	2.6	3.1	4.5	3.0	2.6	1.1	1.9	2.7	3.5	2.1	3.2	2.8	4.9	1.4	4.8	-0.6
Arm fat-free mass (right)	2.4	12.5	20.9	3.2	4.5	3.3	1.6	4.0	4.0	3.8	3.4	4.4	3.8	2.4	4.6	2.5	3.5	4.6	2.8	1.9
Arm predicted mass (right)	2.4	12.5	20.4	3.2	4.4	3.4	1.6	4.0	4.0	3.7	3.4	4.4	3.9	2.3	4.5	2.6	3.6	4.4	2.9	1.8
Number of self-reported non-cancer illnesses	2.4	4.2	9.6	2.7	2.0	2.4	3.1	1.9	2.6	1.2	1.4	1.8	1.4	2.0	2.8	2.3	2.2	-0.3	1.4	-0.5
Arm predicted mass (left)	2.4	12.2	21.6	3.5	4.5	3.1	1.9	3.8	4.2	3.3	3.0	4.3	3.7	3.0	4.6	2.5	3.6	4.1	3.0	1.2
Pack years adult smoking proportion	2.3	3.5	15.5	2.5	1.3	1.3	1.4	1.3	2.0	0.5	1.0	1.3	1.4	3.9	1.0	2.7	2.5	0.7	1.9	-1.6
Waist circumference	2.3	8.5	17.5	3.5	3.0	2.6	3.4	2.7	3.5	1.0	1.4	2.7	3.0	3.3	3.5	2.4	3.9	1.5	4.2	-1.2
Weight	2.3	11.5	21.1	3.5	3.8	3.2	3.2	3.6	3.4	2.4	2.6	3.8	4.0	2.5	4.6	2.6	4.3	2.9	4.4	0.5
Age at first live birth	2.3	4.0	12.5	-2.6	-1.8	-1.6	-2.7	-1.4	-2.7	-1.1	-1.4	-1.3	-0.7	-3.5	-1.1	-3.5	-2.4	-0.8	-0.5	1.1
Medication: Ibuprofen	2.3	2.8	6.8	2.4	2.1	1.4	1.2	2.0	2.6	1.1	1.2	2.1	1.7	1.8	0.8	2.2	1.6	0.7	1.2	-0.4
Rheumatoid Arthritis	2.2	3.0	7.6	0.6	1.3	2.3	0.7	2.3	0.3	2.5	2.8	1.9	1.7	-0.2	1.2	1.8	1.2	1.5	1.6	2.3
BMI	2.2	12.8	28.8	4.6	4.1	2.5	3.7	2.9	4.9	1.4	1.4	3.3	3.3	5.4	4.1	3.3	4.4	2.9	3.7	-1.9
Pack years of smoking	2.2	3.2	15.4	2.3	1.2	1.3	1.4	1.2	1.9	0.4	0.9	1.1	1.2	3.9	0.9	2.7	2.4	0.7	1.7	-1.7
Allergy or Eczema	2.1	5.4	11.4	-3.4	-2.9	-2.2	-0.7	-2.3	-3.2	-2.1	-1.9	-2.7	-3.0	-2.1	-3.1	-2.2	-1.8	-1.6	-1.5	-0.3
Hayfever, allergic rhinitis or eczema	2.1	4.5	9.3	-2.4	-2.5	-2.2	-0.1	-2.4	-2.2	-2.1	-2.0	-2.5	-3.0	-1.2	-3.0	-1.7	-2.0	-1.6	-1.8	-1.1
Forced vital capacity (FVC)	2.1	8.0	20.2	-4.1	-3.0	-2.7	-2.6	-2.2	-4.1	-0.3	-0.9	-2.1	-1.6	-4.5	-1.8	-4.1	-3.0	0.2	-2.9	2.9
Hayfever/allergic rhinitis (self-reported)	2.1	2.7	10.9	-3.0	-1.7	-0.8	-1.2	-0.7	-2.8	0.2	0.2	-0.8	-0.8	-3.3	-0.6	-1.6	-1.3	-0.9	-0.8	2.4
Lung cancer (father)	2.1	2.5	14.5	1.7	0.5	1.2	3.8	0.6	1.1	-0.7	-0.1	0.4	0.9	1.8	0.1	1.6	2.5	-0.1	2.4	-1.7
Illnesses of mother	2.1	2.6	12.8	-2.5	-1.3	-0.0	-2.0	-0.4	-1.8	0.7	0.6	-0.7	-0.4	-3.6	-0.4	-1.9	0.3	1.0	-1.1	3.0
Pain experienced in last month	2.0	3.4	7.6	-1.9	-2.2	-2.2	-2.8	-2.1	-1.6	-1.6	-1.7	-2.0	-1.7	-0.1	-2.7	-2.1	-1.8	-0.8	-1.3	-0.5
Schizophrenia vs Biploar Disorder	1.9	2.5	8.5	2.2	2.2	1.6	-0.7	1.7	2.9	1.5	1.2	2.1	1.6	1.0	1.9	1.4	0.8	0.1	0.8	0.3
Lung FVC	1.9	9.9	14.3	-3.7	-3.6	-3.2	-3.0	-3.5	-3.1	-2.9	-3.2	-3.7	-3.7	-2.2	-3.3	-3.8	-3.2	-2.2	-2.6	-1.0
Taking other prescription medications	1.9	3.0	5.6	2.4	1.8	1.8	1.3	2.2	1.6	1.2	1.3	1.9	2.3	0.4	2.2	1.3	2.3	-0.6	2.3	0.3
Trunk fat mass	1.9	8.2	19.6	2.6	2.6	2.8	4.0	3.0	2.2	1.4	2.0	2.8	3.6	1.3	3.5	2.1	4.4	2.0	4.4	0.3
Arm fat percentage (right)	1.9	7.4	21.2	3.2	2.3	2.0	4.6	2.0	2.8	-0.1	0.6	2.0	2.7	3.3	2.7	2.2	3.9	1.0	4.3	-2.1
Arm fat percentage (left)	1.9	7.7	20.4	3.1	2.4	2.3	4.5	2.3	2.8	0.2	0.9	2.1	2.8	3.0	2.7	2.4	4.2	1.2	4.5	-1.7
Average weekly red wine intake	1.9	2.8	5.5	1.8	2.3	1.4	-0.2	1.9	1.8	1.9	1.5	2.4	2.3	1.2	1.9	1.4	1.3	1.4	1.8	0.7
Illnesses of father: None of the above (group 1)	1.9	2.4	5.0	0.6	1.2	1.2	-1.7	1.6	0.6	2.1	2.0	1.8	2.2	-1.3	1.9	0.4	0.9	1.5	1.2	2.2
Impedance of whole body	1.9	9.8	38.4	-4.3	-4.4	-1.5	-1.0	-1.9	-6.1	-0.8	-0.1	-2.8	-1.2	-6.2	-3.4	-2.4	-1.8	-2.7	-1.4	2.7
Crohns Disease (2017)	1.8	3.9	14.4	-0.3	0.9	1.9	0.1	1.9	-1.1	2.8	3.0	2.0	2.3	-2.5	2.0	0.4	0.5	2.1	1.4	3.8
Bipolar Disorder (2011)	1.8	1.8	5.0	-1.1	-1.3	-1.7	-0.2	-1.5	-1.1	-1.0	-1.1	-1.4	-1.6	-0.0	-1.9	-0.9	-2.0	-0.3	-2.2	-0.9
HbA1C	1.8	2.0	11.4	2.0	0.3	-0.0	1.5	-0.5	1.2	-1.1	-0.9	-0.2	0.2	3.4	-0.4	0.9	0.6	-0.2	1.1	-3.0
Supplements: Zinc	1.8	2.0	5.1	2.3	1.7	1.4	1.0	1.6	1.7	0.9	1.1	1.6	1.4	1.2	1.2	2.1	1.4	0.5	0.8	-0.7
Time employed in main current job	1.8	2.0	6.0	-1.8	-1.3	-1.1	-1.6	-1.3	-1.0	-1.3	-1.1	-1.4	-2.1	-0.6	-1.7	-1.2	-1.6	-0.6	-2.5	-0.5
Serious illness, injury or assault of a close relative in last 2 years	1.8	2.1	5.9	0.4	-1.3	-1.1	0.6	-1.6	-0.3	-1.7	-1.6	-1.8	-1.4	1.6	-1.8	0.0	0.4	-1.9	-1.7	-2.4
Forced vital capacity (FVC), Best measure	1.8	6.6	21.3	-3.9	-2.4	-2.1	-3.3	-1.6	-3.6	0.1	-0.3	-1.4	-1.3	-4.6	-1.3	-3.5	-2.5	-0.1	-2.0	3.1
Medication for cholesterol	1.8	2.7	9.1	-2.5	-1.7	-1.3	-1.5	-1.0	-3.0	-0.1	-0.2	-1.2	-0.6	-2.8	-1.0	-1.8	-2.0	-0.6	-1.0	1.6
Exposure to tobacco smoke outside home	1.7	2.3	4.2	1.2	1.0	1.6	2.0	1.5	1.3	1.5	1.8	1.3	1.6	0.5	1.4	1.5	1.9	1.4	2.1	0.9
Bipolar Disorder or Schizophrenia	1.6	3.8	10.3	-2.3	-2.2	-2.0	-1.0	-2.1	-2.1	-0.9	-1.4	-1.8	-2.0	-2.0	-1.0	-2.4	-3.2	-1.5	-2.7	0.5
Eye problems/disorders: Diabetes related eye disease	1.6	1.7	6.0	1.5	0.5	1.1	1.8	0.7	0.7	-0.5	0.2	0.4	0.1	2.4	-0.5	2.3	1.8	-0.5	1.4	-1.9
Trunk fat percentage	1.6	6.5	19.3	2.2	1.9	2.6	4.0	2.5	1.6	0.9	1.6	2.1	3.1	0.9	2.8	2.0	4.4	1.2	4.4	-0.1
Illnesses of siblings	1.6	2.2	7.1	-2.3	-1.2	-1.4	-2.7	-1.0	-1.9	-0.6	-0.7	-1.1	-0.9	-1.7	-1.1	-1.9	-2.0	0.6	-1.1	1.1
Hair/balding pattern: Pattern 4	1.6	3.9	6.6	1.7	2.3	1.7	0.6	2.3	2.2	2.6	2.4	2.6	1.9	1.6	2.4	1.8	1.2	2.2	1.4	1.5
Basal metabolic rate	1.6	8.6	17.8	2.7	3.7	2.4	1.8	3.2	3.1	2.7	2.5	3.7	3.5	2.2	4.2	1.6	2.8	3.7	2.9	1.3
Lung FEV1/FVC ratio	1.5	7.7	38.2	4.7	4.2	-0.1	1.9	1.0	6.2	0.3	-1.3	2.1	1.4	4.2	2.5	0.8	-0.8	2.5	-0.7	-2.8
Average weekly spirits intake	1.5	1.9	4.6	-2.1	-1.7	-1.3	0.2	-1.3	-1.9	-1.3	-1.1	-1.5	-1.5	-1.3	-0.9	-1.5	-1.3	-1.5	-0.9	0.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	4.1	1.3	1.7	1.7	-0.1	1.7	1.3	2.0	1.9	1.9	1.2	-0.7	1.5	1.9	1.1	0.2	0.1	1.1
Forced expiratory volume in 1-second (FEV1), predicted	1.5	3.0	6.6	-2.0	-1.8	-2.2	-1.3	-1.8	-2.1	-1.4	-1.6	-1.8	-1.5	-2.3	-1.4	-2.6	-1.3	-1.0	-2.0	0.2
Past tobacco smoking	1.4	2.6	6.4	2.4	1.6	1.6	0.5	1.8	2.1	1.3	1.7	1.3	1.4	1.1	0.1	2.5	1.9	0.6	2.4	0.2
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.2	5.9	2.0	1.7	2.1	1.5	1.7	1.9	0.8	1.0	1.6	0.9	0.8	0.6	2.4	1.8	-0.5	0.4	-1.0
Trunk fat-free mass	1.4	7.8	18.5	2.2	3.6	2.0	0.9	3.0	2.8	3.2	2.7	3.7	3.2	1.9	4.3	1.2	1.9	3.8	2.1	2.2
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	6.3	1.8	1.7	0.9	0.4	1.4	2.5	1.1	1.1	1.6	1.3	1.5	0.7	1.6	1.1	1.2	0.8	0.2
Medication for pain relief, constipation, heartburn	1.4	2.3	6.3	-2.5	-1.7	-1.1	-1.7	-1.3	-2.1	-0.6	-0.6	-1.3	-1.4	-1.7	-1.9	-1.5	-1.8	0.6	-1.6	0.9
Whole body fat-free mass	1.4	7.8	17.0	2.5	3.7	2.1	1.2	3.0	3.1	2.8	2.4	3.6	3.2	2.1	4.1	1.3	2.3	3.8	2.4	1.6
Whole body water mass	1.4	8.0	16.5	2.5	3.7	2.2	1.3	3.0	3.2	2.8	2.4	3.6	3.2	2.1	4.1	1.4	2.4	3.9	2.5	1.5
Average weekly champagne plus white wine intake	1.4	2.0	4.8	0.9	1.1	1.7	0.3	1.8	0.9	1.7	2.0	1.4	1.5	0.3	0.2	1.7	1.0	2.2	1.7	1.4
Medication: Atorvastatin	1.4	1.7	4.5	1.4	1.5	1.3	2.0	1.3	1.4	0.9	0.7	1.3	0.9	0.5	1.9	1.0	1.2	0.5	2.1	0.2
Frequency of depressed mood in last 2 weeks	1.3	1.9	5.2	1.3	1.3	2.1	0.8	1.5	1.3	1.7	1.9	1.3	0.8	-0.1	1.1	2.3	1.8	-0.2	0.5	0.7
Relative age of first facial hair	1.3	2.7	5.6	-1.3	-1.2	-2.2	-1.3	-2.1	-0.3	-1.8	-2.3	-1.8	-2.0	-0.1	-1.8	-1.9	-1.5	-0.5	-2.4	-1.3
Diabetes (mother)	1.3	1.7	7.5	1.3	-0.1	0.9	1.6	-0.1	1.1	-0.5	0.2	-0.4	-0.8	2.7	-0.7	2.5	0.3	-1.9	0.3	-1.7
Qualifications: CSEs or equivalent	1.3	1.8	3.8	1.8	1.6	0.9	0.3	1.4	1.2	1.4	1.2	1.6	1.9	-0.2	1.8	1.0	1.6	1.0	1.3	0.7
Medication: Levothyroxine sodium	1.3	2.2	8.6	-0.3	-1.4	-1.5	-0.9	-1.5	-0.7	-2.1	-1.8	-1.5	-1.8	-0.6	-1.4	-0.6	-0.2	-2.9	-1.0	-2.0
Trunk predicted mass	1.3	7.5	18.2	2.2	3.6	2.0	0.9	3.0	2.7	3.2	2.6	3.7	3.2	1.9	4.3	1.2	1.8	3.7	2.0	2.1
Commuting to job workplace: Car/motor vehicle	1.3	1.5	5.3	-1.2	-1.8	-0.4	1.0	-1.3	-1.2	-1.2	-0.6	-1.6	-1.5	-0.6	-2.3	-0.1	0.1	-0.1	-2.1	-0.8
Smoking status: Previous	1.3	1.9	5.9	-2.0	-1.1	-1.3	-0.8	-1.4	-1.7	-0.8	-1.1	-0.9	-1.4	-1.0	-0.3	-1.9	-1.9	-0.3	-2.4	0.1
Medication: Aspirin	1.3	1.6	4.2	-0.5	-0.9	-1.5	0.3	-1.7	-0.3	-1.4	-2.0	-1.6	-1.6	0.9	-0.3	-1.7	-1.6	-1.0	-1.0	-1.4
Medication: Gliclazide	1.3	1.5	5.1	1.4	1.9	1.1	0.9	1.3	1.5	0.8	0.4	1.5	1.0	0.5	2.3	0.7	1.1	0.3	1.8	-0.1
Wears glasses or contact lenses	1.3	1.5	3.6	-1.5	-0.9	-1.1	-0.3	-1.5	-0.3	-1.2	-1.5	-1.4	-1.9	-0.3	-0.7	-1.4	-1.6	-0.1	-1.8	-0.6
Lupus	1.2	1.8	9.2	-0.6	0.5	0.9	-1.2	1.2	-0.7	1.6	1.8	1.2	1.5	-3.0	1.1	0.0	0.5	0.2	0.8	2.3
Blood Red Count	1.2	11.2	66.4	5.1	3.7	1.5	0.9	1.9	6.0	0.5	0.4	2.3	1.2	8.2	1.1	3.9	1.5	1.4	0.3	-3.9
Neuroticism	1.2	3.0	6.3	1.8	2.2	2.5	0.5	2.2	2.1	1.5	1.7	1.8	0.9	-1.6	1.5	2.3	2.1	-1.6	0.7	0.3
Diabetes (father)	1.2	1.5	3.9	1.1	1.5	1.5	2.0	1.2	1.1	1.2	1.2	1.1	0.6	1.5	1.4	1.8	1.2	1.0	0.6	-0.1
Worrier / anxious feelings	1.2	2.3	6.3	0.9	1.9	2.1	0.6	2.2	0.6	1.3	1.6	1.9	1.4	-2.5	1.1	1.6	0.7	-1.4	1.0	0.6
Noisy workplace	1.2	1.4	2.6	-1.4	-1.5	-1.5	-0.5	-1.4	-1.6	-0.8	-0.9	-1.4	-1.3	-1.5	-0.2	-1.6	-0.5	-1.3	-1.1	0.1
Mean time to correctly identify matches	1.2	2.2	6.0	-0.3	-1.1	-1.1	-1.3	-1.3	0.0	-1.9	-1.4	-1.4	-2.4	1.1	-1.5	0.5	-1.3	-2.0	-1.9	-2.3
Supplements: Fish oil (including cod liver oil)	1.2	1.6	3.7	-0.4	-1.0	-1.3	-0.3	-1.5	-0.6	-1.7	-1.9	-1.4	-1.7	0.4	-1.1	-0.7	-1.1	-1.8	-0.9	-1.9
Medication: Lisinopril	1.2	1.6	3.8	-0.0	-1.0	-2.0	-0.3	-1.5	-0.1	-1.6	-1.9	-1.3	-1.4	1.3	-0.4	-1.2	-1.4	-1.0	-0.8	-1.6
Deep venous thrombosis (DVT) (self-reported)	1.2	1.6	3.4	1.7	1.5	1.0	-0.2	1.2	1.7	1.7	1.3	1.5	1.5	1.1	1.8	0.8	0.7	0.8	0.7	1.0
Body Mass Index (BMI) (2010)	1.1	1.5	7.2	2.0	0.8	0.6	1.9	0.5	1.0	-0.6	-0.1	0.6	0.9	2.7	0.3	1.4	0.8	0.7	0.5	-2.0
Blood White Count	1.1	8.5	38.2	3.8	1.8	0.8	6.0	0.2	3.8	-1.1	-1.1	0.3	0.0	6.2	1.3	2.7	2.4	-0.1	1.1	-4.4
Height	1.1	21.9	108.2	-5.7	-1.3	0.7	-2.4	1.8	-6.6	4.7	4.7	1.7	2.9	-9.5	2.8	-3.2	-0.3	3.4	1.4	10.4
Number of treatments/medications taken	1.1	2.1	4.6	2.1	1.9	1.0	1.8	1.4	2.1	0.5	0.4	1.5	1.1	1.3	2.0	1.2	1.5	-0.8	1.1	-0.8
Medication for hormone replacement therapy	1.1	1.2	5.6	1.7	1.1	0.7	-0.2	0.7	1.8	0.1	0.5	0.8	-0.1	2.4	0.0	1.8	0.7	-0.1	-0.2	-1.4
Leg fat-free mass (left)	1.1	6.0	12.4	2.4	3.2	1.8	1.8	2.5	2.9	1.9	1.6	3.0	2.8	2.1	3.5	1.1	2.4	3.2	2.6	0.7
Stomach or abdominal pain in last month	1.1	1.3	5.0	1.0	0.8	1.0	2.0	0.9	0.5	1.6	1.3	0.9	1.2	-0.2	2.2	0.8	0.8	0.8	0.6	1.3
High blood pressure (mother)	1.1	1.6	9.5	0.8	-0.0	-0.6	1.3	-0.6	0.7	-1.2	-1.0	-0.6	-0.9	3.1	-1.2	1.0	-0.3	-0.2	-0.7	-2.6
Impedance of leg (left)	1.1	5.2	29.5	-2.8	-2.6	0.2	-0.8	-0.1	-4.4	1.1	1.8	-0.9	0.4	-5.4	-1.8	-0.7	-0.2	-1.4	-0.4	3.8
Forced expiratory volume in 1-second (FEV1)	1.1	3.8	11.1	-2.5	-1.6	-2.2	-1.8	-1.5	-2.2	0.0	-0.8	-1.2	-0.8	-3.2	-0.9	-3.3	-2.4	1.1	-2.3	2.2
Forced expiratory volume in 1-second (FEV1), Best measure	1.1	3.5	11.7	-2.5	-1.4	-2.1	-2.4	-1.3	-1.8	-0.0	-0.7	-1.0	-0.9	-3.4	-0.7	-3.1	-2.3	0.5	-1.8	2.1
Peak expiratory flow (PEF)	1.1	2.5	7.9	-1.4	0.1	-1.6	-1.2	-0.6	-0.8	1.1	-0.1	0.1	0.3	-1.9	1.2	-2.8	-1.8	2.6	-1.9	2.7
Ever highly irritable/argumentative for 2 days	1.1	1.3	8.0	1.4	0.3	0.9	1.3	0.5	0.9	-0.1	0.5	0.2	0.0	2.8	0.4	2.0	1.0	0.0	1.2	-1.3
Blood clot in the leg (DVT)	1.1	1.4	2.9	1.5	1.4	1.0	-0.2	1.2	1.6	1.6	1.3	1.5	1.3	0.9	1.7	0.9	0.8	0.6	0.7	0.9
Illness, injury, bereavement, stress in last 2 years	1.1	1.3	6.3	-1.3	0.0	0.2	-0.9	0.1	-0.2	1.0	0.7	0.4	0.4	-2.5	0.8	-1.3	-0.6	1.8	0.2	2.5
Ever had bowel cancer screening	1.1	1.3	5.0	-0.9	-1.7	-0.7	-0.1	-1.0	-1.7	-0.6	-0.3	-1.0	-1.0	-1.3	-1.0	-0.3	-1.5	-2.2	-0.9	-0.3
Ever smoked	1.1	1.9	3.9	-1.9	-1.5	-1.5	-1.0	-1.5	-1.8	-1.2	-1.3	-1.2	-1.1	-1.0	-0.1	-2.0	-1.5	-1.1	-2.0	-0.4
Myopia	1.1	1.6	5.3	2.0	1.5	1.0	0.9	1.1	1.8	0.1	0.1	1.0	0.6	2.3	0.3	1.8	0.5	0.0	1.4	-1.7
Breast Cancer	1.0	2.5	7.7	-2.4	-1.9	-1.4	-1.2	-1.3	-2.8	-0.7	-0.7	-1.3	-1.4	-1.9	-0.8	-1.9	-1.9	-1.3	-1.1	0.7
Neuroticism (2016)	1.0	1.5	3.0	1.4	1.7	1.4	-0.1	1.5	1.0	1.4	1.2	1.5	1.2	-1.7	1.7	1.0	0.4	-1.1	0.4	0.6
Chronotype (morning person)	1.0	2.4	9.9	1.1	0.8	1.2	3.1	1.6	-0.2	0.5	1.0	1.1	2.5	1.0	0.2	1.3	1.8	1.6	2.8	-0.1
Townsend deprivation index at recruitment	1.0	1.5	6.0	2.2	0.7	0.1	-0.2	0.6	1.9	-0.4	-0.1	0.5	0.7	2.5	0.4	1.6	0.9	-1.4	0.5	-1.8
Leg predicted mass (left)	1.0	5.5	11.9	2.2	3.0	1.7	1.8	2.4	2.8	1.8	1.5	2.9	2.7	2.1	3.4	1.0	2.3	3.1	2.4	0.6
Fluid intelligence score	1.0	2.1	15.7	1.7	0.6	0.6	-0.1	-0.0	1.8	-0.8	-0.5	0.0	-0.3	4.0	-1.3	1.7	-0.3	0.0	-0.4	-2.7
Mouth/teeth dental problems: Dentures	1.0	1.6	8.1	-1.2	-0.3	0.8	2.8	0.4	-1.3	0.9	1.0	0.2	0.5	-1.9	1.9	-0.7	1.1	0.8	0.4	2.0
Suffer from ‘nerves’	1.0	1.5	9.3	0.5	0.9	1.6	-0.8	1.5	0.5	1.1	1.5	1.2	1.0	-3.1	0.6	1.0	0.8	-0.7	0.2	1.1
Medication: Blood pressure	1.0	1.9	6.8	1.8	1.8	1.1	1.3	1.0	2.6	0.1	-0.0	1.2	0.7	1.7	1.3	1.1	1.5	0.7	1.6	-1.1
Diastolic blood pressure, automated reading	1.0	3.2	10.1	2.7	2.0	1.5	0.5	1.1	3.2	0.9	0.7	1.4	0.9	3.1	0.9	2.0	2.1	1.8	-0.2	-1.4
Unable to work because of sickness or disability	1.0	1.3	4.4	1.7	1.3	0.8	0.8	1.2	1.0	0.9	0.8	1.5	1.7	0.4	2.1	0.7	1.0	0.7	0.9	0.2
Cholesterol lowering medication	1.0	1.5	5.0	1.5	1.1	0.9	2.0	0.5	1.8	0.2	-0.0	0.6	0.5	2.2	1.4	0.7	1.7	0.8	1.4	-0.8
Alzheimer’s Disease (in mother)	0.9	1.0	4.2	1.2	1.0	-0.6	2.0	0.1	0.7	-0.0	-0.7	0.6	1.1	0.4	1.8	-0.9	-0.3	0.1	1.9	-0.4
Ulcerative Colitis (UC)	0.9	1.8	5.9	-1.8	-1.7	-1.1	-0.6	-1.2	-2.4	-0.7	-0.5	-1.3	-1.6	-1.5	-1.1	-1.0	-1.2	-1.8	-0.0	0.6
Age at First Birth	0.9	1.3	3.6	-1.6	-1.2	-1.2	-0.6	-1.2	-1.6	-0.7	-1.1	-1.3	-0.8	-1.9	-0.6	-1.8	-0.3	-0.8	-0.4	0.2
Crohns Disease (2012)	0.9	1.5	5.2	0.3	0.7	1.3	-0.1	1.3	-0.7	1.8	1.9	1.4	1.6	-1.0	1.2	0.3	-0.6	1.1	0.4	2.3
Impedance of leg (right)	0.9	4.2	22.6	-2.0	-2.2	0.6	-0.3	0.3	-4.0	1.3	2.0	-0.6	0.9	-4.8	-1.2	-0.3	-0.0	-1.6	0.1	3.5
Current tobacco smoking	0.9	1.5	6.9	1.6	0.8	0.3	2.6	0.4	1.4	-0.0	-0.2	0.6	0.8	1.4	2.0	0.7	1.7	-0.6	1.1	-1.2
Supplements: Glucosamine	0.9	1.2	3.9	-0.8	-1.0	-0.9	-1.7	-1.0	-1.7	-0.9	-1.0	-0.9	-0.6	-1.1	-0.9	-1.0	-1.2	-2.0	-0.8	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.1	5.0	0.1	0.9	1.4	-0.2	1.7	0.2	1.4	2.0	1.6	1.5	-1.3	1.5	0.9	2.0	1.2	2.2	2.0
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	5.4	1.5	1.0	1.4	0.3	1.4	0.4	0.5	1.1	1.1	0.9	0.3	0.8	2.3	1.8	-1.7	1.4	-0.6
Seen doctor (GP) for nerves, anxiety, tension or depression	0.9	1.3	3.2	0.5	1.8	1.6	0.2	1.5	0.6	1.5	1.1	1.8	1.0	-1.0	1.8	0.7	0.4	0.1	0.6	1.1
Birth weight	0.9	2.0	6.2	-2.2	-0.7	-2.0	-0.5	-0.5	-1.7	0.2	-0.2	-0.2	0.1	-2.1	0.4	-2.5	-1.5	1.4	-0.7	2.5
Comparative body size at age 10	0.9	2.5	5.4	-2.0	-2.0	-2.1	-0.3	-1.8	-2.0	-2.0	-1.9	-1.7	-1.2	-0.1	-1.0	-2.3	-1.3	-0.4	-1.5	-0.7
Pulse wave peak to peak time	0.9	1.1	4.4	-0.4	0.5	0.7	-1.0	1.1	-0.3	1.3	1.5	0.9	1.1	-1.0	-0.0	0.3	-0.0	1.5	1.2	2.1
Health satisfaction	0.9	1.1	4.3	1.2	0.4	0.9	1.0	0.2	1.2	-0.8	-0.2	-0.2	-0.6	1.0	-0.6	1.8	1.7	-1.2	0.3	-2.1
Eye problems/disorders: None of the above	0.9	1.0	3.0	-0.3	-1.3	-0.4	-0.7	-0.7	-1.4	-1.2	-0.6	-1.1	-0.9	0.9	-1.7	-0.1	-1.0	-1.0	-0.7	-1.2
Mood swings	0.9	1.6	3.5	1.7	1.9	1.3	1.1	1.5	1.3	1.1	1.1	1.6	1.4	-1.0	1.7	1.2	0.8	-0.9	0.1	-0.0
Long-standing illness, disability or infirmity	0.9	1.3	5.6	1.8	1.5	1.1	0.6	1.0	1.4	0.5	0.4	1.1	0.7	1.0	2.4	0.8	1.0	-0.8	0.9	-0.6
Back pain experienced in last month	0.9	1.4	4.6	1.5	0.8	1.7	1.6	1.0	0.6	0.2	0.8	0.7	0.3	0.9	1.3	2.1	1.2	-1.6	0.2	-0.9
Mineral and other dietary supplements	0.9	1.2	2.8	0.6	1.1	0.9	1.0	1.2	1.1	1.1	1.3	1.3	1.3	0.6	1.3	0.6	0.7	1.7	1.0	1.1
Leg predicted mass (right)	0.9	4.7	11.0	1.9	2.9	1.5	1.2	2.2	2.7	1.8	1.4	2.7	2.4	1.9	3.1	0.8	2.0	3.3	2.2	0.7
Guilty feelings	0.9	1.3	7.5	0.2	1.2	1.4	0.1	1.2	0.9	1.1	0.9	1.2	0.4	-2.7	1.1	0.3	0.7	-1.4	0.0	1.4
Ever taken oral contraceptive pill	0.9	1.0	4.2	0.3	1.0	0.7	0.4	1.0	0.5	1.4	1.1	1.1	1.3	-0.6	1.0	0.1	0.8	2.0	0.1	1.4
Irritability	0.9	1.5	6.8	1.3	0.6	1.5	1.5	0.6	1.0	0.1	0.6	0.2	-0.6	2.0	-0.7	2.6	1.1	-1.1	0.3	-1.5
Depression (Nagel 2018)	0.8	1.2	3.6	0.6	1.0	1.4	-0.3	0.9	0.8	1.9	1.7	1.0	0.2	-0.6	1.4	1.6	0.6	-0.2	-0.9	1.1
Ovarian Cancer	0.8	1.0	6.1	-0.5	-0.3	-1.4	-2.5	-0.5	-0.1	-0.3	-0.5	0.0	-0.5	-0.2	0.5	-1.5	-1.7	-0.3	-1.3	0.5
Blood Eosinophil Count	0.8	6.0	24.0	3.3	2.2	1.9	2.4	1.5	3.8	0.1	0.6	1.4	0.3	4.9	0.3	3.8	2.5	1.1	1.2	-3.0
Blood Platelet Count	0.8	9.7	25.3	-1.0	-3.2	-2.5	3.7	-3.0	-2.7	-4.8	-4.1	-3.5	-2.4	0.8	-2.6	-1.6	-1.3	-5.0	0.1	-4.7
Cardiovascular Disease	0.8	2.7	13.5	2.7	1.1	0.6	1.8	0.1	2.4	-0.1	-0.5	0.5	0.4	3.7	1.8	1.4	1.0	-0.5	0.6	-2.5
Hearing difficulty/problems: Yes	0.8	1.2	4.6	-0.8	-1.2	-1.5	-1.1	-1.3	-1.0	-0.6	-0.6	-1.1	-1.1	0.1	-0.0	-0.6	-2.2	-1.1	-1.8	-0.1
Ever used hormone-replacement therapy (HRT)	0.8	1.0	3.1	0.9	0.9	0.9	-0.0	0.7	1.3	-0.4	-0.0	0.6	-0.6	1.6	-0.5	1.7	0.6	-1.4	-0.3	-1.8
Medication: Co-codamol	0.8	0.9	4.1	0.1	-0.1	0.5	2.0	0.4	-0.7	0.1	0.4	0.2	0.9	-1.6	1.0	0.3	1.9	-0.3	1.2	0.7
Pain all over the body in last month	0.8	0.9	2.8	1.2	0.7	1.2	0.4	1.1	0.5	1.0	1.2	0.9	1.0	0.2	0.7	1.5	1.7	-0.3	0.8	0.2
Standing height	0.8	7.9	41.1	-2.8	-0.4	0.4	-1.3	1.3	-3.7	3.3	3.2	1.3	2.0	-5.4	1.7	-1.9	-0.7	2.2	-0.1	6.4
Tense / ‘highly strung’	0.8	1.3	4.3	1.3	1.4	2.1	1.8	1.5	1.5	0.5	0.8	1.0	0.7	-0.5	0.0	1.7	0.8	-0.7	0.1	-0.6
Mouth/teeth dental problems: Loose teeth	0.8	1.0	2.7	-0.8	-0.5	-1.0	1.0	-0.6	-1.3	-1.6	-1.6	-0.5	-0.3	-0.8	-0.1	-1.3	-0.4	-1.2	-0.0	-1.5
Age at last live birth	0.8	1.2	5.5	-0.7	0.1	1.2	-0.5	0.7	-0.8	1.0	0.6	0.6	1.2	-2.3	0.7	-1.3	0.2	0.6	1.3	2.2
Medication: Aspirin	0.8	1.1	2.9	0.1	-0.5	-1.0	0.7	-1.3	0.2	-1.1	-1.7	-1.2	-1.3	1.0	0.1	-1.1	-0.9	-1.3	-0.5	-1.5
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.8	0.9	2.3	1.2	1.1	0.8	1.5	0.9	1.3	-0.4	-0.2	0.8	1.1	0.2	1.3	0.3	1.3	-0.4	1.1	-0.8
Leg fat-free mass (right)	0.8	4.5	10.6	1.9	2.8	1.4	1.3	2.1	2.7	1.7	1.4	2.7	2.3	1.9	3.1	0.8	1.9	3.3	2.1	0.6
Osteoarthritis (self-reported)	0.8	1.0	5.4	-0.3	-0.9	0.1	1.2	-0.4	-1.2	-1.2	-1.0	-1.0	-0.7	-0.4	-0.7	-0.1	1.1	-2.3	-0.1	-1.3
Verbal and Numeric Reasoning (VNR)	0.7	1.7	13.1	0.7	0.2	0.1	-0.6	-0.3	0.8	-1.0	-0.8	-0.3	-0.9	3.6	-1.3	1.2	-1.1	0.1	-1.1	-2.5
Average weekly fortified wine intake	0.7	0.8	3.4	-0.6	0.5	0.8	-0.3	1.0	-0.1	0.9	1.2	0.8	0.3	-1.8	0.1	0.7	0.8	0.4	1.4	1.3
Serious illness, injury or assault to yourself	0.7	0.9	4.5	0.6	-0.2	0.1	2.1	0.0	-0.3	-0.5	-0.2	-0.3	-0.1	1.9	-0.0	1.1	0.8	-0.7	1.1	-1.5
High blood pressure	0.7	2.1	8.1	2.2	1.5	0.7	1.0	0.6	2.5	-0.3	-0.6	0.8	0.0	2.9	1.5	1.2	0.8	-0.6	0.8	-2.4
Multivitamins +/- minerals	0.7	0.9	3.6	0.4	-0.5	-0.8	0.7	-0.7	-0.1	-1.4	-1.2	-0.8	-0.9	1.1	-1.3	0.1	-0.2	-0.8	-0.9	-1.9
Chronic bronchitis/emphysema (father)	0.7	0.8	2.9	1.0	0.6	0.8	1.7	0.9	0.1	-0.2	0.2	0.5	0.6	1.5	0.6	1.0	0.8	-0.3	1.6	-0.9
Nervous feelings	0.7	1.4	7.2	0.3	1.3	1.8	-0.1	1.4	0.9	1.0	1.1	1.1	0.6	-2.7	0.9	0.6	0.9	-0.9	0.6	1.1
Ever unenthusiastic/disinterested for a whole week	0.7	0.9	2.3	1.0	1.2	1.3	-0.6	1.2	0.7	0.7	0.8	1.0	0.6	0.2	0.8	1.5	0.9	-0.4	1.5	-0.2
Father’s age at death	0.7	1.0	3.3	-1.4	-0.9	-0.9	-0.2	-0.6	-1.7	-0.4	-0.6	-0.4	0.1	-1.3	-0.7	-1.8	-1.7	-0.1	-0.1	0.8
Pulse rate	0.7	1.1	5.5	1.3	0.3	0.7	0.8	-0.0	1.7	-0.1	0.2	-0.3	-0.5	2.3	0.0	1.7	1.4	-0.3	-0.0	-1.4
Loud music exposure frequency	0.7	0.7	2.0	1.1	0.9	1.0	0.3	0.9	0.5	0.7	0.6	0.7	1.2	1.4	1.2	0.8	0.9	0.6	0.5	0.1
Shortness of breath walking on level ground	0.7	0.9	5.3	0.3	0.5	1.2	1.2	0.5	0.8	-0.0	0.6	0.4	-0.1	1.2	-0.1	1.5	2.3	0.6	0.7	-0.7
Qualifications: College or University degree	0.7	2.2	6.6	-0.5	-1.2	-0.8	-2.5	-1.1	-0.7	-1.2	-0.8	-1.2	-1.4	1.0	-2.6	0.1	-2.4	-2.3	-1.1	-1.2
Hypertension (Self-reported)	0.7	1.8	7.3	1.9	1.5	0.7	0.9	0.5	2.5	-0.4	-0.6	0.7	-0.1	2.7	1.6	0.9	0.6	-0.4	0.6	-2.2
Friendships satisfaction	0.7	0.9	4.6	1.2	0.4	0.8	0.6	0.6	0.8	-0.0	0.4	0.3	0.0	2.1	-0.4	1.9	0.7	-0.6	0.2	-1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.7	0.8	2.8	-0.7	-1.5	-0.6	-0.4	-0.7	-1.7	-0.9	-0.4	-0.9	-0.5	-0.9	-0.8	-0.3	0.3	-1.4	-1.3	-0.6
Mother’s age at death	0.7	0.9	4.6	-1.2	-0.4	-0.7	-2.1	-0.4	-0.7	-0.4	-0.6	-0.1	-0.5	-1.2	-1.0	-1.1	-1.6	0.1	-0.4	0.3
Medication: Bendroflumethiazide	0.7	1.0	4.1	1.1	1.7	0.4	0.7	0.9	2.0	0.8	0.2	1.4	0.5	0.6	2.0	0.0	0.3	0.5	0.5	0.2
Illnesses of father: High blood pressure	0.7	0.8	2.9	-0.5	-0.8	-0.7	-0.2	-0.9	-0.5	-1.1	-0.8	-1.0	-1.4	0.8	-1.7	0.1	0.5	-0.1	-0.9	-1.3
Fractured/broken bones in last 5 years	0.7	0.9	3.4	-1.5	-1.3	-0.2	-0.3	-0.8	-1.4	-0.7	-0.4	-0.9	-0.6	-1.8	-1.1	-0.8	0.6	-0.2	-0.8	0.3
Ever depressed for a whole week	0.7	0.8	3.7	0.5	-0.2	-0.1	1.3	-0.3	0.2	-1.2	-0.8	-0.6	-0.8	0.5	-0.5	0.9	0.4	-1.9	0.3	-1.9
Worry (Nagel 2018)	0.6	1.2	3.2	1.1	1.2	1.8	0.6	1.7	0.7	0.4	0.8	1.0	0.8	-1.4	0.3	1.5	0.7	-1.7	0.8	-0.2
Number of incorrect matches in round	0.6	1.0	4.7	1.3	0.5	0.4	1.1	0.5	1.3	-1.0	-0.7	0.2	-0.1	1.7	-0.3	1.0	0.6	0.1	0.8	-2.2
Had menopause	0.6	0.8	4.3	0.3	0.5	0.2	0.6	-0.2	0.5	-1.1	-1.0	-0.2	-1.0	1.5	-0.2	0.7	0.6	-1.2	-0.3	-2.1
Mouth/teeth dental problems	0.6	1.0	6.0	1.2	1.0	0.0	-2.5	0.4	1.6	0.6	0.1	0.6	0.3	1.7	-0.4	0.6	-0.6	0.8	-0.1	-0.4
Allergy	0.6	1.4	3.0	1.5	1.5	1.3	0.8	1.3	1.2	0.8	0.7	1.3	1.7	0.7	1.6	1.0	1.2	0.8	1.3	0.1
Neck or shoulder pain in last month	0.6	0.9	5.3	1.1	0.7	1.1	2.3	0.7	0.9	0.2	0.3	0.3	0.1	1.6	0.8	1.0	0.5	0.4	0.5	-0.7
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.5	-1.1	-0.4	-0.4	-0.2	-0.2	-1.4	0.7	0.4	-0.1	0.3	-1.6	0.6	-0.8	-0.6	1.1	-0.7	1.4
Pulse rate, automated reading	0.6	1.9	9.6	1.3	0.1	-0.8	1.0	-1.1	1.4	-1.8	-2.0	-0.8	-1.0	2.3	0.2	-0.2	0.4	-1.2	-0.6	-3.1
Had major operations	0.6	0.6	2.2	0.5	0.4	1.3	-0.0	0.7	0.5	0.8	0.9	0.3	0.5	0.6	0.4	1.3	1.3	0.6	1.5	0.2
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	1.9	1.1	0.7	0.8	1.1	0.7	0.1	1.1	0.7	1.0	1.4	-0.5	1.2	0.3	-0.4	-0.4	0.8	0.4
Commuting to job workplace: Walk	0.6	0.7	2.1	0.8	1.3	0.3	-0.7	0.9	1.0	0.7	0.4	1.2	0.7	0.6	1.4	0.6	-0.6	-0.4	0.9	0.1
Eye problems/disorders: Cataract	0.6	0.7	2.8	-0.7	0.4	-0.3	-0.7	-0.2	1.0	1.3	0.6	0.2	-0.2	-0.9	0.9	-0.4	0.3	1.6	-0.9	1.7
Miserableness	0.6	1.0	6.5	-0.4	-0.1	0.3	-1.2	-0.0	-0.3	0.4	0.5	-0.1	-0.7	-2.5	0.0	0.2	0.1	-1.9	-1.7	0.7
Hearing aid user	0.6	0.7	2.9	-0.6	-0.8	-1.0	-1.6	-1.0	-0.4	0.2	0.0	-0.8	-0.9	-0.1	-0.2	-0.3	-1.7	-0.3	-1.1	0.7
Average weekly beer plus cider intake	0.6	0.9	2.6	-0.9	-1.3	-0.6	0.4	-1.3	-0.7	-1.0	-0.9	-1.2	-0.7	-1.0	-1.3	-1.1	0.3	-0.0	-1.6	-0.2
Age started oral contraceptive pill	0.6	0.8	3.4	-1.3	-0.3	0.5	-0.8	0.2	-1.7	0.6	0.7	0.1	-0.2	-1.9	0.7	-0.1	-0.6	-0.7	-0.1	1.4
Vascular/heart problems diagnosed by doctor	0.6	1.6	6.6	-1.9	-1.4	-0.8	-1.3	-0.5	-2.1	-0.0	0.3	-0.8	-0.0	-2.6	-1.7	-1.1	-0.7	0.3	-0.5	1.8
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	3.3	0.8	0.4	0.6	1.3	0.8	-0.1	-0.5	-0.2	0.6	1.0	-0.1	0.8	0.3	1.1	-1.8	1.1	-0.8
Alcohol drinker status: Previous	0.6	0.7	3.3	1.0	1.0	0.7	-0.1	0.8	0.8	0.1	0.4	0.7	0.3	1.8	0.0	1.4	1.0	0.4	0.7	-0.8
Depressed Affect (Nagel 2018)	0.5	1.0	6.1	-0.3	-0.2	0.0	-0.4	-0.6	-0.3	-0.1	-0.0	-0.5	-1.6	-1.4	-0.3	0.6	-0.5	-2.5	-2.0	-0.5
Intelligence (Savage-Jansen 2018)	0.5	1.7	8.1	1.9	1.6	1.0	-0.9	0.8	2.4	0.0	-0.2	1.0	0.3	2.8	0.4	1.2	-0.7	0.2	-0.2	-1.5
Neuroticism (Nagel 2018)	0.5	1.2	4.3	0.9	1.3	1.4	-0.1	1.1	0.7	0.9	0.9	1.0	0.0	-1.9	1.1	1.4	0.2	-2.1	-0.7	0.3
Alzheimer’s Disease (including proxy)	0.5	0.7	3.7	0.8	0.7	-0.1	1.9	0.0	0.3	0.4	-0.5	0.6	1.1	-0.2	1.5	-0.8	0.1	0.6	1.4	0.2
Irritable Bowel Disease (IBD)	0.5	1.3	6.3	-1.1	-0.5	0.4	-0.4	0.4	-1.9	1.2	1.5	0.4	0.3	-2.3	0.5	-0.2	-0.3	0.0	0.9	2.5
Prostate Cancer	0.5	0.7	2.8	0.6	0.3	0.3	1.7	0.1	1.3	-0.2	-0.2	-0.3	-0.4	1.0	-0.5	0.4	1.6	1.1	-0.2	-0.9
Mean Putamen Volume	0.5	0.6	1.8	-0.3	-0.4	-0.1	-0.1	-0.7	-0.3	-1.4	-1.1	-0.7	-0.8	-0.8	-0.9	-0.5	0.4	-1.1	-1.0	-0.9
Heel T-Score	0.5	3.9	12.2	-1.0	0.7	1.9	-1.6	1.7	0.2	2.1	2.8	1.6	1.0	-3.1	0.4	1.2	3.5	1.9	1.9	3.1
Waist Hip Ratio (WHR)	0.5	2.2	5.2	-0.9	-1.9	-1.4	-0.1	-1.8	-0.4	-1.7	-1.5	-2.1	-1.9	-0.2	-1.6	-0.9	-1.4	-2.3	-1.4	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.1	3.2	0.1	0.9	1.0	-0.8	1.3	0.3	0.7	1.2	1.4	1.2	-0.8	0.9	0.8	1.7	0.9	1.8	0.9
Medication: Ramipril	0.5	0.7	3.1	0.1	0.5	1.2	1.3	0.6	1.1	0.2	0.3	0.2	-0.4	1.8	0.7	1.0	1.0	0.5	0.6	-0.4
Medication: Simvastatin	0.5	0.8	4.0	0.5	-0.5	0.1	1.5	-0.8	0.0	-0.6	-0.7	-0.9	-0.9	2.0	0.2	0.4	-0.0	-1.1	0.1	-1.4
Asthma	0.5	1.1	3.0	0.2	0.5	1.4	-0.2	1.3	0.1	1.3	1.7	1.2	1.3	-0.5	-0.2	1.0	1.1	0.7	1.0	1.5
Pulse wave Arterial Stiffness index	0.5	0.6	2.3	0.4	-0.2	-0.5	0.9	-0.8	0.3	-0.8	-1.1	-0.5	-0.7	0.6	0.5	-0.3	0.1	-1.3	-1.1	-1.5
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	1.7	-0.7	-1.1	-0.8	0.4	-0.6	-1.3	-1.3	-0.8	-0.8	-0.2	-0.9	-1.2	-0.4	-0.1	-0.9	-0.2	-0.8
Medication: Amlodipine	0.5	0.7	1.7	-0.2	-0.7	-0.8	-0.4	-1.0	-0.8	-1.0	-1.1	-1.0	-1.1	0.5	-0.6	-0.7	-0.2	-0.8	-1.2	-1.3
Medication: Omeprazole	0.5	0.6	4.1	0.6	0.1	0.5	1.1	0.5	-0.2	-0.7	-0.2	0.3	0.4	0.1	0.4	0.6	1.2	-2.0	0.9	-1.0
Family relationship satisfaction	0.5	0.6	4.2	0.5	0.2	0.6	1.0	0.2	0.1	0.1	0.4	0.1	-0.3	2.0	-1.0	1.5	0.7	0.1	-0.3	-0.9
Smoking status: Current	0.5	0.8	5.3	1.0	0.3	-0.0	2.3	0.0	1.0	-0.2	-0.4	0.1	0.4	1.0	1.4	0.3	1.2	-0.4	0.7	-1.1
Ever had prostate specific antigen (PSA) test	0.5	0.5	1.9	0.1	0.5	0.6	-1.0	0.6	0.0	1.2	0.9	0.6	1.0	-0.8	0.6	0.1	0.0	0.8	-0.1	1.4
Supplements: Calcium	0.5	0.6	2.4	-0.2	-0.8	-1.5	0.2	-0.7	-1.5	-0.7	-0.6	-0.5	-0.5	-0.3	-0.6	-0.5	-0.8	-1.1	-0.4	-0.5
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.2	-0.9	-0.4	-0.8	0.5	-0.9	-0.8	0.5	-0.1	-0.6	-1.1	-0.4	1.1	-1.1	-1.0	0.7	-0.9	0.9
Schizophrenia (2018)	0.4	0.9	3.3	-1.0	-0.9	-0.7	-0.8	-0.8	-0.8	-0.2	-0.5	-0.5	-0.7	-1.4	0.2	-1.3	-1.8	-1.2	-1.1	0.5
Reaction Time	0.4	0.7	3.2	0.7	0.1	-0.1	-0.8	-0.1	0.7	-0.9	-0.3	-0.1	-0.8	1.3	-0.6	1.4	-0.3	-1.1	-0.9	-1.8
HDL Cholesterol	0.4	0.6	2.7	-0.3	0.4	0.2	-0.9	0.5	0.3	1.1	0.7	0.5	0.4	-0.8	1.1	-0.5	-0.4	1.4	0.5	1.6
Smoking Status	0.4	1.1	2.5	-0.5	-0.6	-1.4	1.1	-1.4	-0.2	-1.2	-1.6	-1.0	-0.8	0.8	0.9	-1.3	-0.6	-0.6	-1.1	-1.3
Systolic blood pressure, automated reading	0.4	1.1	4.5	0.5	1.2	1.2	0.7	0.9	1.3	1.4	1.2	1.0	0.4	0.7	0.9	1.0	0.8	2.1	-0.1	0.7
Vitamin and mineral supplements	0.4	0.6	1.8	-0.2	0.4	0.8	-0.2	0.7	0.3	1.0	1.1	0.6	0.4	-0.5	0.8	0.5	0.8	0.8	1.2	1.3
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.7	0.5	0.2	0.6	-0.3	0.2	1.3	-0.2	0.1	-0.3	-0.8	-0.1	-0.8	1.2	0.9	-0.4	0.2	-0.9
Heart attack	0.4	0.6	1.6	-0.7	-0.1	-0.7	0.5	-0.6	-0.6	0.6	-0.1	-0.3	-0.8	-0.2	1.3	-1.1	-1.1	0.9	-0.9	0.9
Falls in the last year	0.4	0.5	2.5	-0.7	0.0	-0.5	-0.7	-0.3	-0.3	-0.7	-1.0	-0.2	-0.4	-1.6	0.2	-1.4	-0.4	-0.8	-0.4	-0.1
Number of live births	0.4	0.6	1.4	0.2	0.7	0.8	0.4	0.8	0.1	1.2	1.2	1.0	0.9	-0.1	0.9	0.6	0.6	0.8	-0.1	1.1
Happiness	0.4	0.5	2.6	0.4	0.0	0.9	0.7	0.2	0.2	-0.1	0.2	-0.1	-0.8	0.3	-1.0	1.6	0.5	-0.7	-1.0	-0.9
Medication: Cholesterol lowering	0.4	0.6	4.1	0.1	-0.3	-0.2	0.7	-0.6	-0.3	-0.6	-0.6	-0.6	-1.0	0.8	0.3	0.2	-0.4	-2.0	0.0	-1.2
Depression (self-reported)	0.4	0.5	1.0	-0.9	-0.7	-0.6	-0.4	-0.4	-1.0	-0.6	-0.5	-0.4	-0.4	-1.0	-0.6	-0.9	-0.8	-0.6	-0.9	0.4
Pulse wave reflection index	0.4	0.5	1.1	-0.5	-0.6	-0.4	-0.3	-0.6	-0.3	-1.1	-0.9	-0.6	-0.9	-0.1	-0.5	-0.5	0.1	-1.0	-1.0	-1.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	3.5	-0.8	-0.8	-0.2	-1.1	-0.5	-0.8	-0.8	-0.6	-0.9	-0.8	0.3	-1.9	0.1	0.1	-0.4	-0.2	-0.7
Medication for cholesterol, blood pressure or diabetes	0.4	0.6	2.3	-0.9	-0.2	0.3	-0.3	0.1	-0.4	0.3	0.6	0.0	0.1	-1.5	-1.4	-0.1	0.6	1.5	-0.2	1.4
Medication: Blood pressure	0.4	0.7	3.0	0.8	-0.1	-0.7	0.1	-0.3	0.3	-0.7	-0.9	-0.4	-0.6	1.7	0.7	-0.0	-0.7	-1.0	-0.5	-1.7
Medication: Seretide 50 evohaler	0.4	0.5	2.7	0.3	-0.4	-0.6	-0.6	-0.6	-0.1	-0.4	-0.5	-0.4	-0.3	1.6	-0.2	-0.2	-0.9	-0.3	-1.5	-0.8
Overall health rating	0.4	0.8	3.7	1.2	0.6	0.6	0.4	0.4	0.8	0.1	0.2	0.5	0.2	0.8	1.6	1.1	1.3	-1.9	0.6	-1.0
Breast cancer (self-reported)	0.4	0.4	2.6	0.6	-0.0	-0.1	0.3	-0.4	0.7	-0.4	-0.3	-0.3	-0.7	1.6	-0.5	0.7	-0.3	-0.6	-0.8	-0.9
Asthma (self-reported)	0.4	0.9	2.5	0.1	0.2	1.1	-0.1	1.1	-0.1	1.2	1.6	1.0	1.2	-0.6	-0.1	0.7	0.9	0.7	1.0	1.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	1.7	-1.0	-1.2	-0.9	-1.2	-1.0	-0.7	-0.5	-0.8	-1.1	-1.0	-1.0	-1.3	-1.2	-1.1	-0.5	-0.6	0.1
Pain type(s) experienced in last month: Hip pain	0.4	0.6	4.8	-0.0	-0.2	0.6	2.2	0.3	-1.0	-0.0	0.2	-0.1	-0.3	-0.2	0.6	0.5	1.4	-0.3	0.3	-0.5
High cholesterol (Self-reported)	0.4	0.7	2.8	1.1	0.5	0.4	1.7	0.0	0.8	0.1	-0.3	0.1	0.1	1.3	1.5	0.4	-0.3	-0.8	0.7	-0.7
Coronary Artery Disease (CAD)	0.3	0.3	1.3	0.8	0.9	-0.4	-0.7	-0.1	0.5	0.2	-0.3	0.8	0.3	0.2	1.1	-0.4	-0.2	-0.7	0.0	0.0
Systolic Blood Pressure	0.3	1.6	8.3	1.1	1.5	1.0	0.2	1.1	1.8	1.2	1.0	1.2	0.8	1.8	0.7	1.1	1.0	2.9	-0.5	0.1
Hypothyroidism (self reported)	0.3	0.6	1.6	0.4	1.3	0.7	0.1	1.1	0.8	0.6	0.7	1.2	0.5	-0.4	1.1	0.4	1.0	0.4	1.0	0.5
Ever had hysterectomy (womb removed)	0.3	0.4	2.4	0.2	-0.2	0.5	1.1	0.1	-0.4	-0.8	-0.4	-0.3	-0.1	-0.1	-0.3	0.4	0.4	-1.6	0.1	-1.1
Severe depression (siblings)	0.3	0.4	1.0	0.2	0.6	0.9	0.4	0.9	0.7	0.3	0.7	0.7	0.3	-1.0	0.1	0.6	0.9	0.2	-0.1	0.2
Fed-up feelings	0.3	0.5	1.8	0.7	0.8	0.4	-0.6	0.7	0.8	0.4	0.5	0.7	-0.3	-1.0	0.8	1.2	0.4	-1.4	-0.2	-0.2
Had other major operations	0.3	0.3	1.3	0.7	-0.2	-0.2	1.1	-0.3	0.5	-0.4	-0.6	-0.3	-0.0	0.5	0.8	-0.1	-0.0	-1.0	0.4	-0.7
Qualifications: None of the above	0.3	0.7	7.5	-0.3	-0.6	-0.1	2.7	-0.4	-0.7	-0.3	-0.1	-0.5	-0.3	-0.7	0.9	-0.1	0.8	-0.9	0.3	-0.0
Qualifications: A levels/AS levels or equivalent	0.3	0.7	2.7	-1.2	-1.1	-0.5	-0.3	-0.6	-1.0	-0.5	-0.3	-0.9	-0.6	0.2	-1.6	-0.4	-1.6	0.6	-0.2	0.3
Exposure to tobacco smoke at home	0.3	0.4	1.3	0.0	0.7	0.7	-0.8	0.8	0.1	0.4	0.5	0.9	0.6	-0.2	0.0	0.7	0.8	-0.2	1.1	0.1
High blood pressure (siblings)	0.3	0.5	2.3	0.8	0.1	0.1	1.5	-0.2	1.1	-0.3	-0.2	-0.2	-0.5	1.2	-0.1	0.6	0.7	-0.5	0.0	-1.1
Wheeze or whistling in the chest in last year	0.3	0.5	1.5	0.4	0.3	1.2	0.4	0.8	0.0	0.3	0.8	0.8	0.7	0.5	0.7	1.1	1.1	-0.1	0.7	-0.0
Number of children fathered	0.3	0.3	1.8	0.1	0.6	0.0	0.6	0.4	-0.7	0.5	0.2	0.5	0.5	0.5	1.3	0.2	0.4	0.3	0.9	-0.0
Emphysema/chronic bronchitis	0.3	0.4	2.6	0.0	-0.3	-0.2	-0.6	-0.5	0.7	-0.6	-0.4	-0.4	-0.4	1.6	0.1	0.2	0.0	0.1	-1.1	-0.9
Migraine (self-reported)	0.3	0.3	1.2	0.6	-0.3	0.1	1.1	-0.2	0.5	-0.6	-0.2	-0.6	-0.2	0.2	-0.3	0.5	1.1	-0.8	0.2	-0.7
Comparative height size at age 10	0.3	1.6	9.2	-1.9	-1.4	-0.5	-0.1	0.0	-3.0	0.1	0.8	-0.3	0.4	-2.7	-0.2	-0.7	0.5	-0.5	0.4	1.7
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	2.2	0.4	0.1	0.9	-0.0	0.7	0.3	0.3	0.7	0.5	0.8	-0.4	0.4	0.2	1.5	0.5	0.3	0.4
Mouth/teeth dental problems: Mouth ulcers	0.3	0.4	2.2	-0.1	-0.4	0.5	-0.1	0.2	-0.5	0.1	0.5	-0.0	0.2	-1.5	0.2	0.6	0.5	-1.4	0.9	0.4
Eye problems/disorders: Glaucoma	0.3	0.4	1.1	-0.3	0.8	0.5	-0.1	0.5	0.7	0.6	0.3	0.8	0.5	-1.0	0.9	-0.7	-0.4	0.6	-0.2	1.1
Risk taking	0.3	0.5	2.5	-0.7	-1.0	0.0	0.2	-0.6	0.2	-0.9	-0.3	-0.7	-0.8	0.3	-1.6	0.0	0.8	-0.1	-0.7	-0.7
Commuting to job workplace: Cycle	0.3	0.4	1.8	-0.4	-0.3	-0.8	-1.1	-0.1	-1.0	0.2	-0.0	-0.1	-0.1	-0.7	0.1	-0.4	-1.4	-0.4	-0.3	0.5
Alzheimer’s Disease (in father)	0.2	0.3	0.8	0.1	-0.0	-0.8	-0.3	-0.7	0.1	-0.1	-0.7	0.0	0.3	0.2	0.7	-0.9	-0.9	0.5	-0.5	-0.1
Major Depression (MDD)	0.2	0.3	1.1	-0.3	-0.2	0.5	-0.8	0.2	-0.4	0.6	0.8	-0.1	-0.6	-0.4	0.4	0.7	0.2	-1.0	-0.2	0.6
Primary Biliary Cirrhosis	0.2	0.3	1.5	-0.0	-0.1	0.9	-0.3	0.5	-0.6	0.6	0.9	0.2	0.2	0.1	-0.5	1.2	0.3	0.1	0.0	0.4
Schizophrenia (2014)	0.2	0.5	2.9	0.1	0.3	-0.4	-1.1	-0.1	1.1	0.6	0.1	0.5	-0.0	-0.2	0.8	-0.5	-1.7	0.2	-1.1	0.4
Triglycerides	0.2	0.3	1.2	-0.5	-0.4	-0.4	0.1	-0.6	-0.2	-0.8	-0.7	-0.7	-1.1	0.1	-0.5	0.1	-0.0	-0.3	-0.7	-0.9
Ulcerative Colitis	0.2	0.3	1.3	-0.3	-0.1	-0.4	-1.2	0.1	-0.8	0.7	0.7	0.2	-0.4	-0.4	0.2	0.4	-0.5	-0.6	0.5	1.1
Respiratory disease	0.2	0.5	2.2	-0.9	-1.2	-0.2	-0.2	-0.2	-1.5	-0.6	0.1	-0.6	-0.4	-0.1	-0.9	-0.0	-0.2	-1.2	0.2	-0.0
Hair Pigment	0.2	4.5	12.6	-0.3	0.9	2.2	0.2	2.0	0.2	2.7	3.0	1.9	2.3	-2.7	1.7	0.8	2.7	2.4	1.9	3.5
Relative age voice broke	0.2	0.2	1.0	0.2	0.1	-0.2	-0.6	-0.2	0.3	-0.3	-0.3	-0.3	-0.7	-0.1	-0.9	0.5	-0.4	0.3	-1.0	-0.8
Diverticular disease/diverticulitis (self-reported)	0.2	0.3	1.0	-1.0	-0.4	0.0	0.1	-0.3	-0.6	-0.0	0.0	-0.3	-0.8	-1.0	0.3	-0.2	-0.3	-0.6	-0.5	0.4
Medication: Atenolol	0.2	0.2	1.0	-0.4	0.1	-0.1	0.9	-0.2	-0.1	-0.4	-0.6	-0.3	-0.6	-0.4	-0.2	-0.5	-1.0	-0.3	-0.4	-0.3
Alcohol usually taken with meals	0.2	0.3	2.1	0.3	-0.0	-0.3	-0.4	0.3	-0.6	0.4	0.4	0.6	1.4	0.3	-0.3	-0.2	-0.6	0.3	0.9	0.3
Hearing difficulty/problems with background noise	0.2	0.3	0.9	0.8	0.0	0.0	0.4	-0.0	0.5	0.1	0.1	-0.1	-0.4	0.9	0.4	0.9	-0.6	-0.9	-0.5	-0.5
Hair/balding pattern: Pattern 3	0.2	0.4	2.1	-0.8	0.0	-0.2	-0.8	-0.1	0.3	0.2	0.2	-0.0	-0.5	-1.4	-0.4	-0.1	-0.2	0.8	-0.9	0.6
Prospective memory result	0.2	0.3	2.2	0.3	-0.1	-0.2	0.0	0.2	0.4	-0.7	-0.2	0.1	0.1	-1.0	-0.3	0.1	-0.0	-1.5	-0.3	-0.5
Birth weight of first child	0.2	0.4	1.7	0.6	0.8	-0.4	-0.4	0.7	0.7	0.0	-0.1	0.8	0.6	0.9	0.9	-0.2	-1.3	0.1	0.4	-0.2
Reason for reducing amount of alcohol drunk: Health precaution	0.2	0.2	1.1	-0.2	0.2	0.7	-0.3	0.4	0.2	0.2	0.4	0.3	0.0	0.3	-0.6	0.4	-0.2	0.5	-1.1	-0.0
Angina (self-reported)	0.2	0.2	1.5	-0.0	-0.2	0.1	1.2	-0.2	-0.0	-0.4	-0.6	-0.4	-0.3	-0.1	-0.1	-0.6	0.1	-0.9	0.3	-0.4
Leg pain on walking	0.2	0.3	1.9	-0.1	-0.2	-0.2	-0.0	-0.0	-0.4	0.3	0.2	0.1	0.0	-1.1	0.8	-0.2	0.1	-0.6	-1.4	0.3
Supplements: Vitamin C	0.2	0.2	0.6	-0.1	-0.2	-0.3	-0.4	-0.3	-0.6	-0.7	-0.6	-0.3	0.1	0.1	-0.3	-0.4	-0.6	-0.8	-0.5	-0.6
Knee pain experienced in last month	0.2	0.4	1.4	-0.8	-0.3	0.4	0.5	-0.3	-0.9	-0.3	-0.1	-0.6	-1.1	-0.8	-0.4	0.2	0.3	-0.2	-1.2	0.0
Handedness (chirality/laterality): Left-handed	0.2	0.2	1.0	-1.0	-0.4	-0.4	-0.5	-0.1	-0.5	-0.3	-0.2	-0.4	-0.4	0.5	-0.4	-0.3	-0.8	-0.3	0.5	0.1
Commuting to job workplace: Public transport	0.2	0.2	1.3	-0.1	0.1	-0.5	-0.9	-0.3	0.1	0.4	-0.1	0.1	0.0	0.7	0.4	-0.4	-1.1	0.2	0.6	0.7
Number of operations (self-reported)	0.2	0.3	0.9	0.6	0.2	1.0	0.6	0.4	1.0	0.1	0.2	0.1	0.0	0.6	0.3	0.9	0.8	-0.5	0.6	-0.4
Basal cell carcinoma (self-reported)	0.2	0.2	1.8	0.5	0.0	-0.5	0.6	0.0	0.2	0.0	-0.1	-0.0	-0.5	0.7	0.3	0.4	-1.4	0.0	-0.5	-0.2
Heart disease (siblings)	0.2	0.3	1.5	0.6	0.8	0.2	0.3	0.4	1.2	0.3	-0.1	0.7	0.0	-0.7	0.7	0.1	0.1	-0.2	-0.8	-0.1
LDL Cholesterol	0.1	0.2	1.5	0.4	0.3	-0.0	-0.4	-0.0	-0.1	0.1	-0.1	0.0	0.3	0.3	1.2	0.1	-0.6	-0.7	0.3	-0.2
Tanning	0.1	1.8	4.3	-1.9	-1.3	-1.3	-0.2	-1.5	-1.5	-0.4	-0.7	-1.3	-0.9	-1.4	-0.4	-2.0	-2.1	0.8	-1.9	0.8
Angina	0.1	0.2	1.2	-0.1	-0.2	0.3	1.1	-0.1	-0.1	-0.4	-0.5	-0.3	-0.3	-0.1	-0.2	-0.6	0.1	-0.8	0.2	-0.2
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.5	0.4	-0.2	0.4	0.7	0.1	-0.1	-0.2	-0.2	-0.1	0.1	-0.4	-0.5	0.2	-0.2	-0.5	-0.6	-0.6
Sitting height	0.1	1.1	3.2	-0.4	0.8	-0.5	-1.2	0.4	-0.3	1.3	0.8	1.0	0.4	-0.1	1.7	-0.8	-1.2	1.6	-0.9	1.8
Glaucoma (self-reported)	0.1	0.2	0.5	0.2	0.6	0.4	0.2	0.2	0.7	0.4	0.2	0.5	0.3	-0.5	0.5	-0.2	-0.2	0.3	-0.1	0.4
Gout (self-reported)	0.1	0.1	0.7	0.1	0.1	0.2	0.2	0.1	-0.1	0.4	0.5	0.2	-0.0	0.4	0.6	0.0	-0.2	0.9	-0.3	0.6
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	0.9	-0.2	-0.1	-0.4	-0.5	-0.3	-0.1	-0.8	-0.6	-0.3	-0.7	-0.3	0.0	-0.2	0.4	-0.9	0.3	-0.8
Medication: Ventolin 100micrograms inhaler	0.1	0.2	0.6	0.5	0.4	0.7	-0.0	0.7	0.1	0.1	0.2	0.7	0.3	0.1	-0.3	0.7	0.1	-0.4	0.3	-0.2
Medication: Allopurinol	0.1	0.1	0.6	0.1	0.3	-0.2	0.2	0.2	0.2	-0.2	-0.1	0.3	0.0	-0.2	0.6	-0.5	0.2	0.8	0.0	-0.1
Heart disease (mother)	0.1	0.1	1.4	0.3	0.1	0.3	0.3	-0.1	0.1	-0.2	-0.2	-0.1	-0.4	0.0	-0.1	0.3	0.1	-1.2	0.1	-0.6
Chest pain or discomfort	0.1	0.1	0.6	0.0	-0.0	-0.0	0.4	0.1	-0.1	-0.3	-0.1	0.1	-0.0	-0.0	-0.2	0.0	0.2	-0.8	0.5	-0.4
Loneliness, isolation	0.1	0.2	1.0	-0.1	0.2	0.1	0.6	-0.0	0.1	0.1	0.3	-0.0	-0.8	-0.6	0.1	0.7	0.1	-1.0	-0.2	-0.2

Hub : Genes

HMG20A

Models

Trait associations