Best TWAS P=3.41e-10 · Best GWAS P=7.14e-10 conditioned to 0.00529
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SMG6 | 0.03 | 0.01 | blup | 144 | 0.01 | 0.00478 | -3.8 | -6.1 | 8.1e-10 | -0.52 | 0.12 | 0.50 | TRUE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | PAFAH1B1 | 0.11 | 0.00 | blup | 61 | 0.04 | 0.00363 | -1.4 | 6.3 | 3.4e-10 | 0.10 | 0.00 | 0.18 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SMG6 | 0.08 | 0.05 | blup | 144 | 0.07 | 0.00013 | -4.4 | -6.0 | 1.5e-09 | -0.53 | 0.44 | 0.32 | FALSE |