TWAS
hub
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Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Impedance of arm (right)
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chr17:1,717,695-2,832,726
Best TWAS P=3.41e-10 · Best GWAS P=7.14e-10 conditioned to 0.00529
1.8M
2M
2.2M
2.4M
2.6M
2.8M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Colon Adenocarcinoma
PAFAH1B1
0.11
0.00
blup
61
0.04
0.00363
-1.4
6.3
3.4e-10
0.10
0.00
0.18
TRUE
1
The Cancer Genome Atlas
Breast Invasive Carcinoma
SMG6
0.03
0.01
blup
144
0.01
0.00478
-3.8
-6.1
8.1e-10
-0.52
0.12
0.50
TRUE
3
The Cancer Genome Atlas
Kidney Renal Papillary Cell Carcinoma
SMG6
0.08
0.05
blup
144
0.07
0.00013
-4.4
-6.0
1.5e-09
-0.53
0.44
0.32
FALSE