[Hub]/) : Traits : Impedance of arm (right) : ← →

chr17:6,652,789-8,515,636

Best TWAS P=3.74e-17 · Best GWAS P=4.19e-15 conditioned to 0.832

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
11	ROSMAP	Brain Pre-frontal Cortex	TNFSF12	0.10	0.04	lasso	6	0.06	9.2e-08	7.74	8.4	3.7e-17	0.90	0.00	1.00	TRUE
19	The Cancer Genome Atlas	Thyroid Carcinoma	ATP1B2	0.04	0.01	blup	40	0.01	1.4e-02	-3.18	-6.0	2.1e-09	-0.24	0.01	0.08	TRUE
20	The Cancer Genome Atlas	Thyroid Carcinoma	CNTROB	0.14	0.07	blup	50	0.10	4.8e-10	-3.76	5.1	2.9e-07	0.01	0.87	0.12	TRUE
6	GTEx	Whole Blood	TNFSF12	0.09	0.03	enet	24	0.04	1.9e-04	7.85	8.3	1.5e-16	0.82	0.00	1.00	FALSE
2	GTEx	Cells Transformed fibroblasts	TNFSF12	0.25	0.22	lasso	8	0.20	7.4e-15	7.74	8.0	1.6e-15	0.99	0.00	1.00	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	TNFSF12-TNFSF13	0.07	0.05	lasso	3	0.02	1.9e-02	7.25	7.4	1.5e-13	0.82	0.01	0.91	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	TNFSF12-TNFSF13	0.03	0.00	lasso	4	0.01	2.9e-02	7.74	7.0	2.7e-12	0.89	0.01	0.75	FALSE
9	METSIM	Adipose	SENP3	0.06	0.03	lasso	3	0.02	4.9e-04	7.25	-7.0	3.2e-12	-0.79	0.09	0.81	FALSE
10	NTR	Blood	TNFSF12	0.06	0.07	bslmm	462	0.07	9.4e-23	7.78	7.0	3.4e-12	0.93	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	TNFSF12	0.04	0.01	enet	9	0.01	4.3e-02	7.25	-6.6	4.1e-11	-0.74	0.00	0.87	FALSE
21	The Cancer Genome Atlas	Thyroid Carcinoma	SHBG	0.04	0.00	blup	59	0.02	4.4e-03	7.70	6.6	4.4e-11	0.65	0.01	0.81	FALSE
16	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ATP1B2	0.04	0.02	blup	39	0.04	2.3e-05	-6.22	-6.6	4.6e-11	-0.34	0.18	0.30	FALSE
3	GTEx	Muscle Skeletal	CHRNB1	0.34	0.18	enet	35	0.24	4.9e-23	7.01	-6.5	9.8e-11	-0.63	0.61	0.39	FALSE
4	GTEx	Skin Sun Exposed Lower leg	ATP1B2	0.08	0.01	lasso	3	0.01	4.8e-02	-5.13	-6.3	2.6e-10	-0.38	0.38	0.05	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CHRNB1	0.04	0.03	blup	57	0.02	1.5e-03	7.01	-6.2	6.3e-10	-0.69	0.00	0.98	FALSE
7	METSIM	Adipose	ATP1B2	0.07	0.04	bslmm	494	0.03	1.2e-05	-6.16	-6.0	1.7e-09	-0.28	0.97	0.02	FALSE
5	GTEx	Testis	ZBTB4	0.26	0.00	enet	35	0.06	1.6e-03	-5.98	6.0	2.0e-09	0.29	0.05	0.17	FALSE
12	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ATP1B2	0.06	0.01	blup	39	0.02	4.3e-03	-6.22	-5.7	1.1e-08	-0.34	0.08	0.16	FALSE
1	GTEx	Adipose Subcutaneous	SNORA48	0.12	0.04	lasso	2	0.04	4.0e-04	-5.24	-5.4	5.6e-08	-0.27	0.39	0.02	FALSE
17	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	ATP1B2	0.13	0.01	blup	42	0.02	6.3e-02	3.76	-5.3	9.7e-08	-0.45	0.01	0.14	FALSE
8	METSIM	Adipose	CHD3	0.06	0.03	blup	509	0.02	6.7e-04	0.33	5.1	2.7e-07	0.28	0.26	0.09	FALSE