[Hub]/) : Traits : Impedance of arm (right) : ← →

chr2:197,134,790-200,117,777

Best TWAS P=3.98e-34 · Best GWAS P=1.21e-33 conditioned to 0.000579

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
18	GTEx	Spleen	RFTN2	0.11	0.03	enet	26	0.05	2.4e-02	12.0	12.2	4.0e-34	0.84	0.05	0.64	TRUE
17	GTEx	Skin Sun Exposed Lower leg	MARS2	0.04	0.05	enet	8	0.03	1.2e-03	12.0	-12.1	7.5e-34	-0.86	0.03	0.96	FALSE
13	GTEx	Lung	RFTN2	0.06	0.08	lasso	8	0.06	2.7e-05	12.0	12.1	1.5e-33	0.86	0.04	0.96	FALSE
19	GTEx	Spleen	MARS2	0.12	0.04	lasso	5	0.00	3.4e-01	12.0	-12.0	6.0e-33	-0.82	0.05	0.56	FALSE
24	GTEx	Thyroid	PLCL1	0.04	0.01	lasso	4	0.00	2.6e-01	11.8	11.9	7.2e-33	0.76	0.14	0.66	FALSE
37	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RFTN2	0.05	0.01	blup	61	0.02	3.1e-02	9.6	11.7	1.4e-31	0.70	0.04	0.40	FALSE
6	GTEx	Breast Mammary Tissue (Female)	SF3B1	0.05	-0.01	lasso	3	-0.01	8.1e-01	9.6	11.4	4.4e-30	0.65	0.05	0.10	FALSE
23	GTEx	Thyroid	SF3B1	0.04	0.02	enet	14	0.02	2.0e-02	9.2	11.3	2.0e-29	0.72	0.10	0.82	FALSE
5	GTEx	Breast Mammary Tissue	SF3B1	0.06	0.06	lasso	4	0.03	6.6e-03	9.6	11.0	5.6e-28	0.61	0.18	0.66	FALSE
26	GTEx	Whole Blood	PLCL1	0.08	0.08	enet	15	0.05	4.1e-05	11.5	10.9	7.1e-28	0.92	0.34	0.66	FALSE
3	GTEx	Adipose Subcutaneous	RFTN2	0.14	0.10	enet	11	0.13	5.3e-11	11.4	10.1	7.4e-24	0.86	0.15	0.85	FALSE
22	GTEx	Testis	SF3B1	0.10	0.07	enet	17	0.08	2.6e-04	9.6	10.1	8.0e-24	0.55	0.48	0.46	FALSE
25	GTEx	Thyroid	RFTN2	0.04	0.01	enet	11	0.01	9.5e-02	12.0	9.9	6.1e-23	0.80	0.04	0.87	FALSE
34	YFS	Blood	PLCL1	0.10	0.10	lasso	9	0.14	1.5e-43	11.6	9.8	1.6e-22	0.83	0.79	0.21	FALSE
14	GTEx	Nerve Tibial	SF3B1	0.06	0.09	lasso	8	0.08	3.3e-06	9.6	9.7	2.5e-22	0.54	0.97	0.03	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SF3B1	0.06	0.07	enet	10	0.07	2.5e-09	9.6	9.7	5.0e-22	0.49	1.00	0.00	FALSE
10	GTEx	Esophagus Mucosa	SF3B1	0.04	0.02	lasso	4	0.01	5.7e-02	9.5	9.4	4.3e-21	0.48	0.32	0.05	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLCL1	0.04	0.00	blup	130	0.02	4.0e-03	-3.7	9.4	6.2e-21	0.65	0.04	0.42	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	MARS2	0.05	0.03	enet	14	0.05	2.2e-07	-8.4	-9.1	8.6e-20	-0.75	0.06	0.94	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	MARS2	0.15	0.14	lasso	4	0.07	2.6e-03	-8.7	-9.0	2.2e-19	-0.63	0.06	0.69	FALSE
11	GTEx	Esophagus Muscularis	SF3B1	0.06	0.02	lasso	4	0.03	1.0e-02	9.7	8.6	6.5e-18	0.41	0.17	0.19	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	SF3B1	0.02	0.01	blup	336	0.01	6.2e-03	8.9	8.6	6.7e-18	0.48	0.57	0.08	FALSE
29	NTR	Blood	PLCL1	0.02	0.01	enet	14	0.02	1.9e-06	11.4	8.4	3.4e-17	0.72	0.21	0.73	FALSE
9	GTEx	Colon Transverse	MARS2	0.17	0.12	lasso	4	0.13	7.4e-07	-8.7	-8.1	6.2e-16	-0.59	0.25	0.40	FALSE
12	GTEx	Lung	SF3B1	0.06	0.04	enet	23	0.02	2.2e-02	9.5	7.6	2.4e-14	0.49	0.41	0.31	FALSE
28	NTR	Blood	ANKRD44	0.03	0.00	bslmm	417	0.02	2.7e-06	9.1	-7.6	3.4e-14	-0.44	0.18	0.69	FALSE
21	GTEx	Testis	ANKRD44	0.33	0.35	enet	15	0.36	6.2e-17	7.7	7.5	5.0e-14	0.38	1.00	0.00	FALSE
27	METSIM	Adipose	PLCL1	0.06	0.01	blup	517	0.05	3.6e-08	-3.7	7.4	1.6e-13	0.73	0.14	0.86	FALSE
36	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MOBKL3	0.03	0.01	blup	32	0.02	6.3e-03	11.0	7.3	2.9e-13	0.63	0.01	0.57	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	HSPD1	0.15	0.04	lasso	7	0.04	2.0e-02	4.4	-7.1	1.6e-12	-0.64	0.11	0.55	FALSE
15	GTEx	Pituitary	HSPD1	0.10	0.03	enet	12	0.06	1.3e-02	1.6	7.1	1.7e-12	0.45	0.08	0.32	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	SF3B1	0.08	0.00	enet	19	0.01	1.6e-01	9.6	7.0	3.6e-12	0.31	0.31	0.05	FALSE
4	GTEx	Adrenal Gland	ANKRD44	0.15	0.05	lasso	5	0.15	3.9e-06	-1.1	-6.7	2.3e-11	-0.38	0.21	0.45	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PLCL1	0.06	0.01	blup	397	0.02	4.9e-04	1.5	6.4	1.4e-10	0.35	0.04	0.71	FALSE
33	YFS	Blood	ANKRD44	0.02	0.00	blup	416	0.01	6.3e-04	-1.8	-6.1	9.5e-10	-0.38	0.14	0.49	FALSE
38	The Cancer Genome Atlas	Prostate Adenocarcinoma	PLCL1	0.07	0.06	blup	130	0.07	1.8e-07	8.7	-6.0	2.1e-09	-0.23	0.99	0.00	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	RFTN2	0.03	0.04	blup	351	0.03	1.5e-04	8.8	-5.9	4.7e-09	-0.24	0.92	0.01	FALSE
20	GTEx	Stomach	SF3B1	0.11	0.00	enet	19	0.00	4.0e-01	9.7	5.2	2.6e-07	0.30	0.09	0.15	FALSE