Best TWAS P=1.97e-08 · Best GWAS P=6.59e-09 conditioned to 0.781
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | RP11-686O6.1 | 0.02 | 0.01 | bslmm | 339 | 0.01 | 1.2e-02 | 4.5 | -5.4 | 7.7e-08 | -0.47 | 0.07 | 0.14 | FALSE |
| 2 | YFS | Blood | FAM117B | 0.47 | 0.52 | lasso | 14 | 0.57 | 1.7e-231 | -4.7 | 5.3 | 1.3e-07 | 0.25 | 0.02 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | FZD7 | 0.09 | 0.11 | lasso | 3 | 0.09 | 5.1e-06 | 5.6 | 5.6 | 2.0e-08 | 0.77 | 0.01 | 0.99 | TRUE |