[Hub]/) : Traits : Impedance of arm (right) :

chr2:205,851,076-207,874,372

Best TWAS P=7.72e-15 · Best GWAS P=2.81e-13 conditioned to 0.0221

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex NDUFS1 0.10 0.09 lasso 9 0.09 1.2e-10 7.0 -7.6 4.1e-14 -0.90 0.03 0.97 FALSE
2 GTEx Adipose Subcutaneous NDUFS1 0.08 0.05 lasso 5 0.01 2.0e-02 6.2 -6.6 3.7e-11 -0.79 0.05 0.94 FALSE
3 GTEx Adipose Subcutaneous AC007383.4 0.08 0.05 lasso 4 0.04 2.8e-04 6.0 -5.8 6.2e-09 -0.74 0.05 0.94 FALSE
4 GTEx Adipose Visceral Omentum AC007383.4 0.10 0.01 lasso 4 0.02 4.8e-02 4.4 -5.4 5.7e-08 -0.49 0.05 0.55 FALSE
5 GTEx Artery Aorta NDUFS1 0.11 0.07 enet 29 0.01 6.7e-02 7.1 -6.2 7.2e-10 -0.76 0.04 0.94 FALSE
6 GTEx Artery Tibial NDUFS1 0.16 0.15 enet 14 0.15 3.9e-12 6.7 -6.8 7.4e-12 -0.78 0.06 0.94 FALSE
7 GTEx Brain Cerebellum NDUFS1 0.13 0.15 lasso 2 0.10 5.3e-04 6.0 -6.0 1.7e-09 -0.73 0.05 0.85 FALSE
8 GTEx Brain Cerebellum AC007383.4 0.23 0.05 lasso 3 0.18 3.9e-06 7.2 -6.4 2.0e-10 -0.77 0.03 0.89 FALSE
9 GTEx Brain Frontal Cortex BA9 NDUFS1 0.36 0.33 lasso 3 0.32 3.9e-09 6.0 -5.9 4.5e-09 -0.71 0.05 0.95 FALSE
10 GTEx Brain Frontal Cortex BA9 AC007383.4 0.39 0.36 lasso 3 0.35 3.3e-10 6.5 -6.0 1.6e-09 -0.74 0.05 0.95 FALSE
11 GTEx Brain Putamen basal ganglia NDUFS1 0.16 0.06 enet 6 0.05 2.9e-02 5.9 -7.1 1.4e-12 -0.76 0.06 0.61 FALSE
12 GTEx Breast Mammary Tissue (Female) NRP2 0.29 0.03 lasso 6 0.06 5.7e-03 5.6 5.2 1.6e-07 0.53 0.06 0.41 FALSE
13 GTEx Breast Mammary Tissue (Female) AC007362.1 0.46 -0.01 lasso 14 0.00 4.6e-01 6.0 5.1 2.9e-07 0.65 0.05 0.50 FALSE
14 GTEx Cells Transformed fibroblasts NDUFS1 0.33 0.42 enet 28 0.40 3.2e-32 6.7 -7.1 1.1e-12 -0.81 0.04 0.96 FALSE
15 GTEx Cells Transformed fibroblasts AC007383.4 0.18 0.15 enet 28 0.17 4.5e-13 6.7 -7.0 2.2e-12 -0.73 0.05 0.95 FALSE
16 GTEx Colon Sigmoid AC007383.4 0.15 0.14 enet 13 0.09 3.8e-04 6.9 -7.4 1.1e-13 -0.82 0.04 0.94 FALSE
17 GTEx Colon Transverse AC007383.4 0.14 0.09 lasso 2 0.06 8.8e-04 6.2 -6.5 1.0e-10 -0.75 0.05 0.84 FALSE
18 GTEx Esophagus Gastroesophageal Junction NDUFS1 0.16 0.09 enet 22 0.03 2.4e-02 6.9 -7.8 7.7e-15 -0.74 0.04 0.94 TRUE
19 GTEx Esophagus Gastroesophageal Junction AC007383.4 0.21 0.17 enet 11 0.14 8.5e-06 6.9 -6.9 5.4e-12 -0.78 0.04 0.95 FALSE
20 GTEx Esophagus Mucosa NDUFS1 0.09 0.05 lasso 2 0.02 8.6e-03 7.0 -7.3 2.0e-13 -0.78 0.04 0.93 FALSE
21 GTEx Esophagus Mucosa AC007383.4 0.16 0.08 enet 26 0.10 5.8e-07 6.9 -5.9 4.7e-09 -0.67 0.08 0.92 FALSE
22 GTEx Esophagus Muscularis NDUFS1 0.17 0.19 enet 21 0.18 5.1e-11 6.9 -6.9 4.1e-12 -0.73 0.04 0.96 FALSE
23 GTEx Esophagus Muscularis AC007383.4 0.10 0.13 enet 4 0.10 1.3e-06 6.9 -6.9 4.5e-12 -0.78 0.05 0.95 FALSE
24 GTEx Heart Atrial Appendage AC007383.4 0.12 0.10 enet 21 0.09 9.8e-05 7.1 -6.8 1.4e-11 -0.70 0.04 0.96 FALSE
25 GTEx Heart Left Ventricle AC007383.4 0.17 0.13 enet 19 0.16 9.7e-09 6.9 -7.0 1.9e-12 -0.73 0.04 0.96 FALSE
26 GTEx Liver AC007383.4 0.27 0.10 lasso 4 0.03 4.4e-02 5.9 -6.2 5.7e-10 -0.70 0.04 0.60 FALSE
27 GTEx Muscle Skeletal NDUFS1 0.20 0.14 enet 20 0.12 4.0e-12 7.0 -6.8 1.5e-11 -0.77 0.06 0.94 FALSE
28 GTEx Muscle Skeletal AC007383.4 0.23 0.18 enet 38 0.20 2.1e-19 7.0 -6.0 2.5e-09 -0.75 0.08 0.92 FALSE
29 GTEx Nerve Tibial NDUFS1 0.13 0.08 enet 14 0.05 3.1e-04 6.0 -6.8 1.4e-11 -0.72 0.07 0.93 FALSE
30 GTEx Nerve Tibial AC007383.4 0.14 0.06 lasso 6 0.05 3.0e-04 7.1 -7.5 7.1e-14 -0.83 0.04 0.96 FALSE
31 GTEx Pituitary AC007383.4 0.31 0.05 enet 15 0.04 3.9e-02 5.9 -5.8 5.1e-09 -0.66 0.06 0.63 FALSE
32 GTEx Testis NDUFS1 0.15 0.08 lasso 6 0.08 2.1e-04 6.6 -7.1 1.5e-12 -0.71 0.09 0.81 FALSE
33 GTEx Thyroid NDUFS1 0.21 0.10 enet 39 0.05 7.4e-05 7.1 -5.3 1.4e-07 -0.55 0.03 0.97 FALSE
34 METSIM Adipose NDUFS1 0.12 0.18 lasso 4 0.17 5.2e-25 6.7 -6.6 3.3e-11 -0.78 0.05 0.95 FALSE
35 METSIM Adipose ZDBF2 0.03 0.00 bslmm 436 0.00 1.1e-01 -5.3 6.4 1.4e-10 0.64 0.33 0.42 FALSE
36 ROSMAP Brain Pre-frontal Cortex INO80D 0.22 0.34 lasso 2 0.35 2.0e-47 6.0 6.7 2.2e-11 0.90 0.61 0.39 FALSE
37 ROSMAP Brain Pre-frontal Cortex ZDBF2 0.12 0.11 lasso 2 0.11 8.0e-14 5.1 5.2 1.9e-07 0.48 1.00 0.00 FALSE
38 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma NDUFS1 0.05 0.05 enet 6 0.06 2.3e-07 7.0 -5.3 1.3e-07 -0.50 0.03 0.97 FALSE
39 The Cancer Genome Atlas Brain Lower Grade Glioma NDUFS1 0.05 0.03 blup 51 0.04 6.2e-05 7.1 -6.5 9.1e-11 -0.75 0.04 0.96 FALSE
40 The Cancer Genome Atlas Thyroid Carcinoma GPR1 0.05 0.04 lasso 3 0.04 1.7e-04 6.6 -6.5 5.6e-11 -0.70 0.22 0.34 FALSE