TWAS hub - FAM117B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1320	0.0410	5.3e-10	0.088	0.099	0.102	0.099	0.110	8.2e-11	4.1e-12	2.1e-12	4.1e-12	2.7e-13
2	GTEx	Cells Transformed fibroblasts	0.0670	0.0310	5.4e-04	-0.002	NA	0.029	NA	0.008	4.6e-01	NA	2.7e-03	NA	7.2e-02
3	GTEx	Esophagus Mucosa	0.1280	0.0550	6.3e-04	0.090	NA	0.086	NA	0.086	1.3e-06	NA	2.3e-06	NA	2.1e-06
4	GTEx	Heart Atrial Appendage	0.1350	0.0710	3.4e-03	0.005	NA	-0.006	NA	-0.005	1.8e-01	NA	8.7e-01	NA	6.7e-01
5	GTEx	Pancreas	0.1350	0.0590	2.8e-03	0.060	NA	0.069	NA	0.061	1.6e-03	NA	7.6e-04	NA	1.4e-03
6	GTEx	Whole Blood	0.0630	0.0280	1.4e-03	0.062	NA	0.046	NA	0.056	2.4e-06	NA	4.3e-05	NA	7.1e-06
7	METSIM	Adipose	0.1018	0.0384	8.8e-08	0.063	0.045	0.047	0.052	0.057	9.6e-10	2.3e-07	1.3e-07	2.4e-08	5.9e-09
8	NTR	Blood	0.1660	0.0348	0.0e+00	0.126	0.140	0.139	0.145	0.148	1.7e-38	9.4e-43	1.9e-42	1.7e-44	2.6e-45
9	YFS	Blood	0.4670	0.0470	0.0e+00	0.525	0.560	0.566	0.567	0.567	2.4e-206	4.4e-227	2.8e-231	2.2e-231	1.7e-231
10	TCGA	Breast Invasive Carcinoma	0.0721	0.0325	2.4e-03	0.005	0.013	0.023	NA	0.004	3.0e-02	7.9e-04	1.5e-05	NA	5.2e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
High cholesterol (Self-reported)	9.4	16.7	30.5	5.5	2.4	-3.9	3.9	4.9	4.9	4.3	3.3	3.5	-3.4
Cholesterol lowering medication	6.8	10.0	19.6	4.4	1.9	-2.9	3.5	3.5	3.2	3.3	2.6	2.5	-3.1
Heart attack	6.4	8.1	17.3	-4.2	-0.3	-0.1	-3.5	-3.0	-2.9	-3.3	-3.5	-3.0	1.6
Crohns Disease (2017)	6.0	13.2	22.0	-4.3	1.1	1.5	-3.8	-4.2	-4.7	-4.5	-4.1	-4.3	0.5
Bilateral oophorectomy (both ovaries removed)	5.9	6.8	12.5	3.5	-0.8	-2.6	1.9	3.2	3.0	2.9	2.9	2.8	-0.9
Medication: Atenolol	5.8	7.3	12.9	-3.6	2.4	2.2	-1.0	-3.0	-2.7	-3.0	-3.4	-3.3	0.7
Heart attack/myocardial infarction (self-reported)	5.6	7.3	15.8	-4.0	-0.2	-0.1	-3.2	-2.9	-2.7	-3.1	-3.2	-2.7	1.8
Allergy or Eczema	5.5	14.3	24.0	4.8	-0.3	-1.6	4.4	3.9	4.2	4.9	4.4	4.6	0.5
Mouth/teeth dental problems: Dentures	5.2	8.8	15.6	-2.9	1.9	4.0	-0.7	-3.9	-3.7	-3.0	-3.0	-3.5	-0.0
Pulse rate	5.1	8.6	17.9	-3.5	2.0	4.2	-2.3	-3.4	-2.9	-2.5	-2.6	-2.7	2.3
Pulse wave reflection index	4.9	6.1	11.5	3.4	-1.4	-3.4	0.4	3.0	2.3	1.6	2.0	2.5	-3.0
Crohns Disease (2012)	4.4	7.1	12.0	-3.0	0.2	1.1	-2.8	-2.8	-3.5	-3.5	-3.3	-2.9	-0.9
Respiratory disease	4.4	9.7	22.7	4.8	0.6	-1.5	1.8	3.4	3.7	4.1	3.5	3.5	-1.6
Hayfever, allergic rhinitis or eczema	4.4	9.6	16.1	3.9	-0.4	-1.7	3.6	3.1	3.2	3.8	3.8	4.0	0.5
Asthma	4.1	8.1	16.7	4.1	-1.4	-1.6	1.3	2.9	3.5	3.6	3.3	3.4	-1.4
Coronary Artery Disease (CAD)	4.0	4.8	15.8	-4.0	0.4	1.6	-0.8	-1.6	-1.5	-2.0	-2.2	-2.1	3.4
Medication: Simvastatin	3.9	5.7	8.5	2.9	1.1	-2.9	1.8	2.7	2.8	2.8	2.3	2.6	-0.9
Headache pain in last month	3.9	6.8	12.5	3.5	0.7	-0.3	3.3	3.1	2.8	2.7	2.8	2.4	-2.3
Asthma (self-reported)	3.9	7.8	16.5	4.1	-1.3	-1.6	1.3	2.8	3.4	3.5	3.3	3.4	-1.3
Depressed Affect (Nagel 2018)	3.8	8.0	14.9	3.8	-2.2	-2.1	0.6	2.7	3.2	2.7	2.6	3.0	-3.9
Neuroticism	3.7	8.9	24.7	3.4	-4.0	-3.2	0.1	2.8	2.6	1.7	1.8	2.4	-5.0
Number of self-reported non-cancer illnesses	3.7	6.4	12.5	3.5	1.7	-1.7	2.5	3.0	2.8	2.7	1.9	2.0	-2.8
Average weekly beer plus cider intake	3.7	5.4	12.9	-1.4	2.0	-0.6	-2.0	-1.5	-1.8	-2.5	-3.2	-2.9	-3.6
Miserableness	3.6	6.2	14.8	3.1	-2.1	-2.3	0.5	2.3	2.7	2.0	2.1	2.6	-3.8
Impedance of arm (right)	3.5	16.3	27.8	4.4	-4.5	-3.6	0.6	4.2	4.5	4.6	4.7	5.3	0.2
Mouth/teeth dental problems	3.4	5.3	13.8	1.7	-2.0	-3.7	-0.5	2.8	2.8	2.1	2.3	2.6	0.6
Medication: Ramipril	3.4	4.4	7.5	-2.2	2.5	1.2	-1.2	-2.7	-2.7	-2.1	-2.2	-2.4	0.2
Irritable Bowel Disease (IBD)	3.3	7.8	15.2	-3.2	0.5	1.3	-2.9	-3.5	-3.9	-3.5	-2.9	-3.1	0.9
Supplements: Zinc	3.3	3.6	6.4	-1.9	1.2	1.5	-2.5	-2.2	-2.0	-2.0	-2.3	-2.1	-0.2
Knee pain experienced in last month	3.3	5.1	13.9	2.9	-0.3	-3.7	-0.8	2.0	2.1	2.0	1.6	1.9	-3.1
Diverticular disease/diverticulitis (self-reported)	3.1	3.7	9.1	3.0	0.8	-1.1	1.2	2.8	2.1	2.0	1.5	1.8	-1.8
Medication: Cholesterol lowering	3.1	4.8	9.4	2.3	0.5	-2.6	0.3	2.6	3.1	2.7	2.1	2.6	-0.4
Exposure to tobacco smoke at home	3.1	3.4	7.5	2.7	0.9	-0.9	1.2	2.2	2.2	2.1	1.5	1.5	-2.3
Neuroticism score	3.0	6.3	21.1	2.8	-2.6	-2.4	-0.6	2.7	2.7	1.6	1.3	1.9	-4.6
Impedance of arm (left)	3.0	14.1	25.8	3.7	-4.3	-2.9	0.5	3.8	4.4	4.4	4.4	5.1	1.1
Ever had bowel cancer screening	3.0	3.6	9.4	1.8	-1.6	0.3	3.1	2.5	1.4	1.6	2.5	1.9	0.4
Allergy	2.9	6.6	14.1	-3.8	0.5	1.7	-2.1	-2.5	-2.6	-3.2	-3.2	-3.3	0.2
Medication for cholesterol	2.9	4.4	7.1	-2.7	-1.1	2.2	-1.6	-2.4	-2.3	-2.4	-1.8	-2.0	2.0
HDL Cholesterol	2.8	4.7	8.3	2.2	-1.7	-2.2	1.6	2.8	2.9	2.2	2.1	2.5	-0.4
Cardiovascular Disease	2.8	9.3	14.9	3.4	0.8	-3.4	2.5	3.9	3.8	3.5	2.6	3.3	-2.0
Neuroticism (Nagel 2018)	2.7	6.3	13.7	3.2	-2.6	-2.5	0.2	2.7	2.5	1.9	1.9	2.3	-3.7
Schizophrenia vs Biploar Disorder	2.7	3.5	6.3	2.5	-1.9	-0.3	1.2	1.8	1.6	2.1	2.5	2.3	-1.2
Mood swings	2.7	4.9	9.2	2.7	-0.8	-2.1	0.2	2.7	2.8	2.2	1.6	2.2	-3.0
Lupus	2.6	3.9	11.9	-1.2	2.3	3.5	1.2	-1.6	-1.9	-1.5	-1.7	-2.1	-1.7
Angina	2.6	3.5	8.5	-2.9	0.3	0.3	-1.9	-1.6	-1.7	-2.3	-2.6	-2.0	0.9
Angina (self-reported)	2.6	3.4	8.6	-2.9	0.4	0.6	-1.5	-1.8	-1.7	-2.2	-2.5	-2.0	1.1
Pain experienced in last month	2.6	4.3	6.4	-2.5	0.2	0.3	-1.8	-2.3	-2.5	-2.5	-2.1	-2.1	2.4
Worry (Nagel 2018)	2.5	5.3	9.3	2.5	-2.6	-1.9	0.8	3.0	2.7	2.1	2.0	2.1	-2.4
Ovarian Cancer	2.5	3.3	12.3	-2.2	-0.4	2.5	0.1	-1.6	-1.6	-1.4	-0.9	-1.3	3.5
Taking other prescription medications	2.5	3.8	7.9	2.8	0.7	0.5	2.4	1.9	2.2	2.6	2.2	2.1	-0.6
Ever taken oral contraceptive pill	2.5	2.8	5.5	-1.9	0.4	-0.2	-2.4	-1.4	-1.4	-1.9	-2.2	-2.1	-1.2
Diastolic blood pressure, automated reading	2.5	7.9	16.1	4.0	-0.5	-2.0	2.1	2.6	2.8	2.9	3.0	2.8	-3.8
Number of treatments/medications taken	2.4	4.3	7.1	2.6	1.8	0.0	2.4	2.2	2.3	2.7	2.1	2.0	-0.8
Maternal smoking around birth	2.4	3.5	7.7	2.8	-0.8	-0.4	2.1	2.0	1.8	1.7	1.6	1.6	-2.7
Ever used hormone-replacement therapy (HRT)	2.3	2.9	5.9	2.4	-0.7	-1.2	1.2	1.8	2.2	1.9	1.6	2.0	-1.2
Frequency of depressed mood in last 2 weeks	2.2	3.1	13.1	2.3	-1.7	-1.4	0.2	1.2	1.5	1.1	0.9	1.3	-3.6
Medication for hormone replacement therapy	2.2	2.4	8.9	2.4	0.4	-1.1	0.4	1.1	1.7	1.4	0.8	1.1	-3.0
Medication: Atorvastatin	2.2	2.8	6.1	2.5	0.4	-1.6	0.5	1.9	2.2	1.9	1.2	1.7	-1.4
LDL Cholesterol	2.1	3.3	12.5	2.5	0.3	-2.4	-0.8	1.6	1.6	1.4	0.5	0.7	-3.5
Time employed in main current job	2.1	2.4	4.2	-2.0	-0.3	0.9	-1.7	-1.6	-1.8	-1.9	-1.9	-1.9	-0.5
Hair/balding pattern: Pattern 3	2.1	3.1	7.6	0.7	0.3	-0.5	2.8	1.8	1.9	1.9	1.8	1.9	2.3
Wheeze or whistling in the chest in last year	2.1	3.8	9.9	3.1	0.1	-1.6	1.4	2.1	1.7	1.5	1.6	1.6	-3.1
Blood White Count	2.0	14.8	30.6	4.7	-1.3	-2.2	2.2	4.2	4.5	4.7	4.8	5.5	-0.3
Relative age of first facial hair	2.0	4.1	12.7	1.8	-3.6	-1.4	0.9	1.7	1.9	1.8	2.4	2.6	0.2
Age at first live birth	2.0	3.5	8.1	-2.8	0.6	1.2	-0.8	-1.7	-2.3	-2.3	-2.1	-2.3	1.3
Arm predicted mass (right)	2.0	10.3	18.0	-4.0	3.5	3.6	-0.3	-2.8	-3.1	-3.4	-3.8	-4.2	0.1
Qualifications: NVQ or HND or HNC or equivalent	2.0	2.4	4.8	2.2	-2.2	-1.4	0.7	1.2	1.1	1.5	2.0	1.7	-0.3
Irritability	2.0	3.4	8.4	1.9	-2.7	-2.4	-0.6	1.7	1.6	0.9	0.8	1.2	-2.9
Rheumatoid Arthritis	1.9	2.6	4.9	1.9	0.7	-0.3	0.7	1.9	2.2	2.2	1.9	1.9	0.2
Hair/balding pattern: Pattern 2	1.9	2.5	5.8	-1.1	0.8	1.6	-2.4	-1.9	-1.5	-1.4	-1.6	-1.5	-1.5
Shortness of breath walking on level ground	1.9	2.2	3.7	1.9	-0.9	-1.7	-0.5	1.8	1.6	1.7	1.5	1.7	-1.0
Reaction Time	1.8	3.5	6.2	-2.2	-0.6	1.3	-2.2	-1.2	-2.2	-2.3	-2.3	-2.5	0.6
Diabetes (mother)	1.8	2.3	5.1	2.3	-0.1	-0.5	1.7	1.1	1.6	1.8	2.1	2.0	-0.2
Forced vital capacity (FVC), Best measure	1.8	6.5	18.4	-4.3	-0.5	3.4	-0.8	-2.2	-2.4	-2.5	-2.3	-2.6	2.3
Arm fat-free mass (right)	1.8	9.1	15.8	-3.7	3.7	3.2	-0.5	-2.6	-2.9	-3.1	-3.5	-4.0	0.0
Medication: Seretide 50 evohaler	1.8	2.1	4.2	1.9	-0.6	-0.6	2.1	1.7	1.5	1.6	1.4	1.5	-0.7
Number of full sisters	1.8	2.2	14.8	0.8	-0.1	-0.5	-1.0	-1.2	-0.9	-1.0	-1.3	-0.8	-3.9
Suffer from ‘nerves’	1.8	2.8	5.8	2.3	-0.1	-0.9	1.1	2.2	2.0	1.6	1.4	1.1	-2.4
Illnesses of father: Heart disease	1.8	2.5	6.5	-2.4	2.6	1.2	-0.3	-1.0	-0.6	-0.9	-1.3	-1.0	2.5
Guilty feelings	1.8	2.7	21.2	1.6	-0.5	-1.0	-0.8	0.6	0.3	-0.3	-0.8	-0.4	-4.6
Alcohol drinker status: Never	1.8	2.1	10.4	-0.1	3.2	2.2	2.2	-0.0	0.3	0.5	-0.2	-0.8	-0.6
Ever smoked	1.8	3.2	11.7	1.5	-3.4	-3.0	-1.1	0.5	0.5	-0.2	0.7	1.2	-2.3
Alzheimer’s Disease (in father)	1.7	1.8	8.4	1.6	2.4	0.7	0.7	-0.0	0.3	0.5	-0.1	-0.3	-2.9
High blood pressure (siblings)	1.7	2.4	4.3	2.1	0.6	-1.4	0.9	1.7	1.8	2.0	1.5	1.5	-1.5
Family relationship satisfaction	1.7	2.1	4.5	-0.7	-0.8	0.2	-2.1	-1.7	-1.9	-1.6	-1.2	-1.1	-1.8
Impedance of whole body	1.7	8.7	15.5	2.8	-3.7	-2.2	-0.2	3.0	3.7	3.5	3.2	3.9	0.8
Depression (Nagel 2018)	1.6	2.3	9.9	1.8	-1.9	-1.6	-1.0	0.8	1.0	0.7	0.5	0.9	-3.2
Alzheimer’s Disease (including proxy)	1.6	2.3	12.6	2.1	-0.2	-2.0	-0.4	0.7	0.9	0.5	-0.1	0.6	-3.6
Bipolar Disorder (2011)	1.6	1.6	4.6	-1.3	2.1	1.6	-0.3	-1.0	-0.9	-0.8	-1.3	-1.4	0.7
Lung FVC	1.6	8.3	19.1	-4.4	-2.3	1.9	-2.0	-2.5	-3.1	-3.4	-3.1	-3.0	2.2
Medication: Co-codamol	1.6	1.9	4.2	1.5	-0.2	0.3	1.5	1.6	1.9	2.0	1.4	1.4	-0.2
Townsend deprivation index at recruitment	1.6	2.2	10.5	2.5	0.2	-1.7	0.3	0.9	1.0	0.6	0.1	0.6	-3.2
Chronic bronchitis/emphysema (father)	1.6	1.9	11.5	1.4	1.6	0.4	1.4	0.5	0.4	0.4	-0.5	-0.5	-3.4
Emphysema/chronic bronchitis	1.6	1.8	4.3	-0.2	1.9	0.2	-0.7	-0.9	-1.4	-1.4	-1.6	-1.4	-2.1
Ever had stillbirth, spontaneous miscarriage or termination	1.6	1.7	3.7	-0.7	0.2	0.9	-1.1	-1.1	-1.5	-1.5	-1.8	-1.9	-1.3
Risk taking	1.6	2.3	6.9	2.2	-1.1	-1.2	1.5	1.5	1.0	0.8	0.9	1.5	-2.6
Triglycerides	1.5	2.5	5.3	2.3	1.3	-1.2	0.5	2.0	2.0	1.8	1.0	1.0	-1.6
Type 2 Diabetes (T2D) (2012)	1.5	1.8	5.9	1.4	1.7	0.5	2.2	0.5	0.7	0.7	0.7	0.4	-2.4
Hayfever/allergic rhinitis (self-reported)	1.5	2.0	3.7	1.5	0.4	-1.2	1.3	1.5	1.7	1.9	1.5	1.8	0.7
Falls in the last year	1.5	2.0	5.8	2.2	-0.3	-1.6	-0.4	1.3	1.2	1.0	0.8	1.1	-2.4
Noisy workplace	1.5	1.9	7.9	1.0	2.8	0.1	1.4	0.2	0.2	0.0	-0.8	-0.7	-2.6
Illness, injury, bereavement, stress in last 2 years	1.5	1.8	3.9	0.6	-0.7	-2.0	-0.0	1.8	1.9	1.4	1.2	1.8	0.1
Loneliness, isolation	1.5	2.0	12.2	1.9	-0.6	-0.9	-0.1	1.1	1.1	0.6	0.3	0.4	-3.5
Smoking Status	1.4	3.4	10.1	2.3	-3.2	-2.0	-1.2	0.6	0.5	0.4	0.9	1.3	-3.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.4	1.8	7.8	1.3	-1.6	-1.5	-1.8	0.2	0.2	0.0	-0.1	0.4	-2.8
Relative age voice broke	1.4	2.1	4.8	1.2	-2.2	0.5	1.2	1.6	1.6	1.5	1.7	1.6	0.5
Stomach or abdominal pain in last month	1.4	1.8	5.1	2.0	1.7	0.7	2.3	1.2	0.7	1.1	0.9	0.3	-1.2
Medication for pain relief, constipation, heartburn	1.4	2.4	5.3	-2.3	-1.1	0.8	-1.9	-1.4	-1.4	-1.4	-1.2	-0.9	2.2
Commuting to job workplace: Walk	1.4	1.5	2.9	1.7	-1.1	-1.5	0.6	0.9	0.9	1.2	1.5	1.6	0.2
Arm fat-free mass (left)	1.4	7.3	14.0	-3.2	3.0	2.4	-0.8	-2.4	-2.8	-3.0	-3.3	-3.7	-0.4
Arm predicted mass (left)	1.4	6.9	13.0	-3.0	3.2	2.4	-0.6	-2.3	-2.8	-2.8	-3.1	-3.6	-0.4
Average weekly spirits intake	1.3	1.6	11.5	1.0	-0.4	-0.1	-0.6	-0.8	-1.1	-0.6	-0.3	-0.6	-3.4
Hearing difficulty/problems: Yes	1.3	1.9	4.5	-0.6	1.3	-0.3	-0.8	-1.2	-1.1	-1.6	-2.1	-1.8	-1.8
Current tobacco smoking	1.3	2.2	12.5	2.4	-0.6	-0.4	-0.6	0.5	0.6	0.9	0.6	0.8	-3.5
Age when periods started (menarche)	1.3	3.1	6.2	-2.4	-2.5	1.4	-2.1	-1.5	-1.4	-1.7	-1.3	-1.0	1.5
Qualifications: CSEs or equivalent	1.3	1.7	4.9	1.6	1.9	1.4	2.2	0.8	0.9	1.1	0.8	0.5	0.2
Alcohol usually taken with meals	1.3	2.1	12.8	-0.6	0.8	1.3	1.3	1.2	1.1	1.0	0.7	0.4	3.6
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.0	13.1	-2.5	-0.7	3.6	0.1	-2.1	-1.2	-1.2	-1.0	-1.1	0.8
Number of full brothers	1.3	1.6	4.4	2.1	-0.4	-0.6	-0.0	1.2	1.6	1.6	1.4	1.4	-0.6
Worry too long after embarrassment	1.3	2.2	7.8	1.3	-2.1	-2.6	-0.2	1.2	0.4	-0.3	-0.2	0.0	-2.8
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	5.9	1.4	1.4	0.9	2.4	1.1	1.2	1.0	0.9	0.8	-1.0
Eye problems/disorders: None of the above	1.3	1.5	3.8	1.3	-1.9	-0.9	0.8	0.8	1.4	1.1	1.2	1.6	0.0
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.3	-1.0	1.5	1.1	0.9	-1.5	-1.5	-1.3	-1.3	-1.3	-0.1
Migraine (self-reported)	1.3	1.6	12.3	1.5	0.2	-0.8	-0.4	0.7	0.3	0.1	-0.1	0.0	-3.5
Medication: Ibuprofen	1.3	1.6	2.9	1.7	0.8	-0.4	1.3	1.1	1.1	1.4	1.5	1.1	-1.6
Mean time to correctly identify matches	1.3	2.5	4.3	-2.0	-0.6	1.3	-1.4	-1.4	-1.9	-1.9	-1.8	-2.1	0.7
Chest pain or discomfort	1.3	1.8	3.3	-0.8	0.2	0.8	-0.5	-1.5	-1.8	-1.7	-1.7	-1.6	-1.6
Smoking status: Current	1.3	2.1	11.8	2.3	-0.6	-0.7	-1.0	0.4	0.6	0.8	0.5	0.7	-3.4
Bipolar Disorder (2018)	1.2	1.8	3.7	-1.8	0.7	-0.1	-1.9	-1.1	-1.2	-1.6	-1.9	-1.3	0.4
Verbal and Numeric Reasoning (VNR)	1.2	2.9	17.6	-1.2	4.2	2.4	1.1	-0.1	-0.2	-0.2	-0.9	-1.4	0.6
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	4.6	-1.1	1.0	2.1	-0.4	-1.4	-1.5	-1.0	-0.5	-0.6	0.2
Fed-up feelings	1.2	2.3	10.3	1.8	-1.5	-1.3	-1.5	0.2	0.7	0.6	0.5	1.3	-3.2
Illnesses of siblings	1.2	1.6	3.4	-1.8	-0.9	1.1	-0.1	-1.1	-1.3	-1.7	-1.2	-1.2	1.5
Trunk fat-free mass	1.2	6.7	12.7	-3.4	2.6	2.6	-0.5	-2.1	-2.7	-2.9	-3.2	-3.6	-0.1
Medication: Ibuprofen (e.g. Nurofen)	1.2	1.5	3.5	1.7	1.2	-0.7	1.5	0.8	0.7	1.2	1.2	0.7	-1.9
Forced expiratory volume in 1-second (FEV1), Best measure	1.2	3.7	9.4	-3.1	0.6	3.0	-0.1	-1.5	-1.7	-1.8	-1.7	-2.1	1.6
Trunk predicted mass	1.2	6.6	12.5	-3.3	2.6	2.6	-0.4	-2.0	-2.6	-2.9	-3.1	-3.5	-0.1
Birth weight of first child	1.2	2.1	3.7	1.8	-1.7	-1.9	0.7	1.7	1.3	1.4	1.4	1.5	-0.3
Peak expiratory flow (PEF)	1.2	2.7	5.5	1.0	-1.0	1.6	2.3	1.5	1.7	1.8	1.9	1.6	1.4
Ever had hysterectomy (womb removed)	1.1	1.3	3.7	1.5	0.8	-0.3	1.9	0.8	0.8	0.8	0.9	0.7	-1.7
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.4	8.1	-2.1	-2.0	2.8	-0.2	-2.0	-1.0	-1.1	-0.4	-0.3	1.1
Past tobacco smoking	1.1	2.1	10.4	-0.6	3.2	2.0	1.0	0.3	0.6	1.1	0.1	-0.4	1.8
Nervous feelings	1.1	2.1	4.8	1.2	-2.2	-1.6	0.2	1.8	1.5	1.1	1.3	1.3	-1.3
Had menopause	1.1	1.4	2.9	1.6	-1.7	-1.2	1.4	0.6	0.8	0.9	0.9	1.2	-0.9
Forced vital capacity (FVC)	1.1	4.1	12.5	-3.2	-1.9	3.0	-0.0	-1.1	-1.3	-1.2	-0.7	-0.9	3.5
Arm fat percentage (right)	1.1	4.2	11.0	3.3	3.1	-0.4	1.3	1.6	1.7	2.1	1.7	1.1	-2.2
Medication: Blood pressure	1.1	2.0	5.6	-2.4	1.5	0.0	-1.0	-1.4	-1.3	-1.5	-1.8	-1.5	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.3	1.2	-1.2	-0.5	1.0	0.6	1.0	1.0	1.8	1.8	-0.4
Commuting to job workplace: Car/motor vehicle	1.1	1.3	6.8	-1.1	1.4	2.6	0.4	-0.4	-0.4	-0.5	-1.0	-0.9	0.5
Whole body fat-free mass	1.1	6.2	11.5	-3.0	2.9	2.5	-0.5	-2.0	-2.5	-2.7	-3.0	-3.4	-0.2
Whole body water mass	1.1	6.2	11.6	-3.1	2.8	2.4	-0.5	-2.1	-2.6	-2.7	-3.0	-3.4	-0.1
Mother’s age at death	1.1	1.3	2.6	1.0	-1.4	-1.1	0.4	1.2	0.6	1.2	1.6	1.5	1.0
Fractured/broken bones in last 5 years	1.1	1.5	3.0	-0.2	1.4	-0.6	-1.3	-0.3	-1.0	-1.3	-1.7	-1.6	-1.6
Systolic Blood Pressure	1.0	5.0	11.0	0.3	-3.3	-3.0	-0.0	1.4	1.8	2.0	2.6	2.9	2.2
Type 2 Diabetes (T2D) (2018)	1.0	1.8	3.1	1.8	1.7	0.2	1.3	0.6	1.2	1.6	1.8	1.5	-1.0
Pack years adult smoking proportion	1.0	1.5	9.0	1.3	2.0	0.5	0.3	-0.1	0.3	0.3	0.0	-0.3	-3.0
Had other major operations	1.0	1.3	3.7	-0.9	1.9	1.1	1.4	-0.5	-0.9	-0.9	-0.9	-1.2	0.9
Medication: Paracetamol	1.0	1.6	5.0	2.1	2.0	0.2	1.2	0.5	0.3	0.7	0.7	0.1	-2.2
Exposure to tobacco smoke outside home	1.0	1.4	5.3	1.8	2.3	0.0	0.8	0.7	0.8	1.2	0.4	0.4	-1.4
Pulse rate, automated reading	1.0	3.1	6.2	-1.8	2.5	2.3	-1.9	-2.0	-1.4	-0.9	-1.4	-1.5	1.2
Age at last live birth	1.0	1.5	4.3	-2.1	0.5	0.6	-1.1	-1.0	-1.0	-1.3	-1.5	-1.4	0.9
Arm fat percentage (left)	1.0	3.9	10.8	3.1	3.3	0.1	1.4	1.5	1.8	2.1	1.6	1.0	-1.9
Medication: Lisinopril	1.0	1.3	6.2	-0.6	-1.8	-0.8	-0.5	0.5	0.4	0.4	1.0	1.0	2.5
Ever depressed for a whole week	1.0	1.2	6.2	1.1	1.1	1.0	1.4	0.1	-0.4	0.1	0.1	-0.5	-2.5
Commuting to job workplace: Cycle	1.0	1.3	6.4	1.1	-2.5	-1.4	-0.2	1.0	0.7	0.5	0.7	1.0	0.3
Supplements: Calcium	1.0	1.1	3.0	1.2	1.5	-1.4	0.3	1.2	0.6	0.4	-0.5	0.2	-1.7
Intelligence (Savage-Jansen 2018)	0.9	2.8	13.9	-1.3	3.7	2.3	0.0	-0.3	-0.5	-0.8	-1.6	-1.9	0.3
HbA1C	0.9	1.0	2.1	-1.0	0.7	0.0	-1.2	-0.9	-0.9	-1.3	-1.5	-1.3	-0.3
Blood Eosinophil Count	0.9	7.0	19.8	4.5	-0.5	-1.6	1.3	3.0	2.4	3.2	3.0	3.2	-1.1
Heel T-Score	0.9	7.2	28.0	-1.2	-5.2	5.3	1.9	-1.7	-0.1	0.5	1.5	0.9	2.5
BMI	0.9	5.3	34.5	0.9	5.9	1.8	1.0	-0.7	-0.7	-0.6	-1.4	-1.9	-2.7
Medication: Metformin	0.9	1.2	3.6	1.1	1.9	1.1	1.6	0.5	0.7	0.9	0.6	0.5	-1.0
Frequency of tiredness / lethargy in last 2 weeks	0.9	1.5	3.0	1.5	-0.0	-0.9	0.1	1.7	1.7	1.4	0.9	1.4	-1.2
Number of live births	0.9	1.3	2.9	-1.3	-0.1	1.0	-1.0	-1.7	-1.5	-1.2	-0.8	-1.0	0.6
Glaucoma (self-reported)	0.9	1.1	3.8	-1.5	-0.3	1.5	0.3	-0.4	-0.8	-0.7	-0.7	-0.8	1.9
Medication: Ventolin 100micrograms inhaler	0.9	1.2	2.8	1.7	-0.8	-0.3	0.1	1.4	1.1	1.1	1.2	1.2	-0.9
Leg fat percentage (right)	0.9	3.1	17.7	1.8	4.2	0.8	0.2	0.3	0.8	0.8	-0.1	-0.6	-2.8
Reason for reducing amount of alcohol drunk: Health precaution	0.9	1.0	3.2	0.5	0.0	-0.5	1.2	1.3	1.1	0.9	0.8	0.7	1.8
Neck or shoulder pain in last month	0.9	1.3	5.1	0.9	1.3	0.7	1.8	0.4	1.0	0.7	0.0	0.0	-2.3
Leg fat mass (right)	0.9	3.5	21.9	0.5	4.7	1.8	0.2	-0.5	-0.3	-0.2	-1.0	-1.6	-2.4
Average weekly red wine intake	0.9	1.3	4.9	-0.0	-1.3	-0.6	-0.5	1.5	1.4	0.6	0.4	0.9	2.2
Mineral and other dietary supplements	0.9	1.2	2.2	-1.4	-0.9	-0.9	-1.5	-1.2	-1.5	-1.2	-0.6	-0.8	0.6
Basal metabolic rate	0.9	5.2	10.4	-2.6	3.2	2.5	-0.4	-1.7	-2.1	-2.2	-2.6	-3.1	-0.2
Leg fat percentage (left)	0.9	3.4	17.0	2.3	4.1	0.7	0.3	0.6	1.1	1.2	0.3	-0.3	-2.9
Basal cell carcinoma (self-reported)	0.9	1.0	2.2	0.8	0.0	0.6	0.7	1.1	1.4	1.3	1.5	1.1	0.6
Pack years of smoking	0.9	1.3	7.4	1.0	1.9	0.5	0.1	-0.2	0.0	0.0	-0.2	-0.5	-2.7
Alzheimer’s Disease (in mother)	0.8	0.9	3.2	0.5	-1.5	-1.5	-0.7	0.1	-0.1	-0.5	-0.7	-0.2	-1.8
Breast Cancer	0.8	2.0	8.5	-1.1	1.9	2.9	1.4	-1.2	-0.7	-0.2	-0.1	-0.8	1.5
Fasting Glucose	0.8	0.9	3.6	1.4	-0.4	-1.9	0.3	0.3	0.6	0.9	0.8	0.8	-0.8
Chronotype (morning person)	0.8	1.8	5.6	0.3	1.2	2.4	2.2	0.3	0.4	1.1	1.0	0.5	1.7
Other serious medical condition/disability diagnosed by doctor	0.8	1.0	2.5	1.6	0.5	0.2	0.2	1.2	1.0	1.5	1.3	0.8	0.0
Average weekly fortified wine intake	0.8	0.9	4.2	0.0	2.1	1.4	1.4	0.1	0.1	0.0	-0.3	-0.7	-0.4
Body mass index (BMI)	0.8	3.3	22.6	0.9	4.8	1.4	0.8	-0.4	-0.4	-0.2	-0.7	-1.4	-2.1
Diabetes (self-reported)	0.8	1.2	2.3	1.5	0.6	0.2	1.4	0.7	0.9	1.2	1.5	1.2	-0.8
Fluid intelligence score	0.8	1.7	12.3	-0.4	3.5	1.4	1.0	0.5	0.1	0.1	-0.4	-0.5	0.4
Father’s age at death	0.8	1.1	2.3	0.8	-0.8	-1.1	0.0	0.8	1.3	1.3	1.5	1.5	0.6
Worrier / anxious feelings	0.8	1.5	6.2	0.6	-2.5	-1.2	-0.3	1.2	1.3	0.7	0.9	1.1	-1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	2.6	1.6	1.1	0.5	1.3	1.0	1.1	1.1	0.7	0.5	-1.5
Hypothyroidism/myxoedema (self-reported)	0.8	1.6	5.2	-1.0	1.1	0.2	-1.3	-2.3	-1.9	-1.0	-0.8	-0.8	0.9
Birth weight	0.8	1.8	4.0	-0.9	0.5	-0.5	-1.1	-1.0	-1.2	-1.4	-2.0	-2.0	-1.9
Pulse wave peak to peak time	0.8	0.9	1.9	-1.2	1.4	1.1	0.5	-1.0	-0.6	-0.5	-0.9	-1.2	0.9
Alcohol intake frequency.	0.8	1.9	13.2	1.0	3.6	1.3	1.1	-0.5	-0.0	0.7	0.3	-0.3	-0.9
Illnesses of siblings: Diabetes	0.8	1.0	2.1	-0.7	1.2	0.8	-0.7	-1.4	-1.5	-1.0	-0.9	-0.8	-0.2
Long-standing illness, disability or infirmity	0.8	1.2	3.8	1.9	1.2	-0.2	-0.1	0.7	0.7	1.1	0.6	0.4	-1.9
Osteoporosis (self-reported)	0.8	1.0	4.0	-0.2	2.0	0.3	-0.3	-0.1	-0.3	-1.0	-1.4	-1.2	-1.4
Osteoarthritis (self-reported)	0.8	1.1	4.9	1.6	1.0	-1.3	-0.5	-0.3	-0.3	0.1	-0.1	-0.3	-2.2
Illnesses of father: High blood pressure	0.8	1.0	2.4	1.5	-0.7	-0.8	0.7	0.7	0.7	0.8	1.1	1.2	-1.1
Alcohol drinker status: Previous	0.8	0.9	3.3	1.2	0.7	-0.3	1.4	0.1	0.4	0.7	0.8	0.6	-1.8
Leg fat mass (left)	0.8	3.2	20.5	0.9	4.5	1.7	0.4	-0.2	0.0	0.2	-0.7	-1.2	-2.3
Mean Putamen Volume	0.7	0.8	2.0	1.1	0.3	-1.0	0.1	1.4	1.3	0.8	0.3	0.2	-1.2
Sensitivity / hurt feelings	0.7	1.3	3.1	0.9	-1.8	-1.1	-1.6	1.0	1.0	0.3	0.5	0.7	-1.4
Leg fat-free mass (left)	0.7	3.5	9.1	-2.1	3.0	1.9	-0.1	-1.2	-1.6	-1.8	-2.1	-2.5	-0.3
Sitting height	0.7	4.8	14.3	-3.8	0.9	3.3	0.1	-1.3	-1.6	-1.4	-1.6	-1.9	3.1
Waist circumference	0.7	2.6	13.3	1.1	3.6	0.3	0.0	0.5	-0.1	-0.1	-1.0	-1.2	-2.9
Hearing difficulty/problems with background noise	0.7	1.2	6.6	1.2	1.4	-0.3	0.5	0.4	0.3	-0.2	-0.9	-0.7	-2.6
Forced expiratory volume in 1-second (FEV1)	0.7	2.3	6.7	-2.3	-0.9	2.6	0.3	-0.8	-1.0	-0.9	-0.5	-0.9	2.5
Prospective memory result	0.7	0.9	3.8	-0.9	-2.0	-1.3	-1.1	-0.8	-0.5	-0.5	0.1	0.6	0.1
Comparative body size at age 10	0.7	1.9	7.5	0.2	1.6	0.7	2.7	0.9	1.2	1.5	1.3	0.7	1.3
Overall health rating	0.7	1.4	7.7	1.1	1.8	0.1	0.4	0.8	0.7	0.6	-0.4	-0.2	-2.8
Supplements: Vitamin C	0.7	0.9	1.7	-0.8	1.3	0.7	0.6	-1.0	-1.2	-0.9	-0.8	-1.1	0.3
Average weekly champagne plus white wine intake	0.7	1.0	3.0	1.2	0.9	-0.9	1.7	0.9	0.6	1.0	0.9	0.8	0.7
Financial situation satisfaction	0.7	0.9	3.5	-0.1	0.2	-0.6	-0.5	-0.5	-0.9	-1.1	-1.2	-1.2	-1.9
Primary Biliary Cirrhosis	0.6	0.9	2.0	1.1	0.3	-0.4	0.8	0.3	0.2	0.9	1.4	1.3	1.4
Blood Platelet Count	0.6	6.5	38.6	2.6	6.2	0.6	0.3	2.7	1.9	1.9	-0.2	-0.3	-2.0
Waist Hip Ratio (WHR)	0.6	2.6	6.2	1.8	-0.2	-2.5	-1.9	2.3	1.8	1.4	0.4	1.2	-1.2
Hypothyroidism (self reported)	0.6	1.4	4.8	-0.8	0.7	0.8	-0.9	-2.2	-2.0	-1.1	-0.8	-0.9	0.5
Lung FEV1/FVC ratio	0.6	2.9	12.7	1.6	2.8	-0.8	0.2	-0.3	-0.6	-0.6	-1.4	-1.6	-3.6
Diabetes (father)	0.6	0.7	1.6	-1.1	-0.2	0.6	-0.8	-1.3	-1.0	-1.0	-0.7	-0.7	0.5
Trunk fat percentage	0.6	2.5	5.5	2.4	2.2	0.1	0.4	1.4	1.9	2.1	1.5	1.2	-1.1
Impedance of leg (left)	0.6	3.1	6.4	1.4	-2.5	-1.1	-1.2	1.6	2.4	2.1	1.6	2.2	0.1
Leg predicted mass (left)	0.6	3.4	8.6	-2.0	2.9	1.9	-0.2	-1.2	-1.6	-1.8	-2.1	-2.5	-0.3
Number of incorrect matches in round	0.6	1.1	2.0	-1.2	-1.2	-0.2	-0.5	-1.0	-1.4	-1.1	-1.0	-1.1	1.0
Pain all over the body in last month	0.6	0.6	1.7	-0.8	-0.3	1.1	0.4	-1.1	-1.3	-0.7	-0.3	-0.6	0.6
Hip circumference	0.6	2.4	14.4	0.2	3.8	1.9	0.9	-0.3	-0.5	-0.2	-0.6	-1.3	-1.5
Pulse wave Arterial Stiffness index	0.6	0.7	2.1	0.8	-1.4	-0.9	-0.7	0.8	0.4	0.2	0.6	0.9	-0.8
Loud music exposure frequency	0.6	0.7	3.2	0.9	-1.0	-1.8	-0.1	0.5	0.2	0.1	0.6	0.5	-0.9
Body fat percentage	0.6	2.5	9.3	2.2	3.0	0.5	0.4	1.0	1.5	1.7	1.0	0.6	-1.7
Leg pain on walking	0.6	0.8	1.6	0.7	-1.0	-0.8	-0.3	0.8	0.7	0.9	1.0	1.3	1.1
Smoking status: Previous	0.6	0.9	5.0	-0.2	-2.2	-1.6	-0.4	-0.1	-0.5	-1.0	-0.2	0.2	-0.4
Leg fat-free mass (right)	0.6	3.0	7.1	-1.9	2.7	1.9	-0.2	-1.2	-1.6	-1.6	-1.9	-2.3	-0.0
Leg predicted mass (right)	0.6	3.0	6.9	-1.9	2.6	1.9	-0.2	-1.2	-1.6	-1.6	-1.9	-2.3	0.0
Wears glasses or contact lenses	0.6	0.6	1.2	-0.4	-0.4	0.3	-1.0	-1.1	-1.1	-1.1	-0.8	-0.8	0.4
Tinnitus: Yes, now most or all of the time	0.6	0.7	2.5	0.6	-0.8	-1.6	-1.1	0.8	0.8	0.6	0.3	0.7	-0.1
Eye problems/disorders: Glaucoma	0.6	0.7	1.6	-1.2	-0.1	1.0	-0.9	-0.4	-0.8	-0.6	-0.8	-0.9	1.1
Medication: Paracetamol	0.6	0.9	3.4	0.6	1.8	0.8	0.4	-0.4	-0.7	-0.4	-0.4	-0.8	-1.8
Number of operations (self-reported)	0.6	0.9	5.2	0.4	1.3	-0.1	2.3	0.8	0.5	0.3	0.4	0.2	0.8
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	1.8	0.9	0.4	-1.1	0.2	1.4	1.2	0.8	0.6	0.6	-0.0
Schizophrenia (2018)	0.5	1.1	5.3	0.7	-2.3	0.0	-1.4	0.4	0.2	0.6	1.2	0.9	0.5
Ulcerative Colitis (UC)	0.5	0.9	2.5	-0.9	-0.1	0.4	-0.9	-1.4	-1.6	-1.1	-0.7	-0.7	1.0
Prostate Cancer	0.5	0.7	1.3	0.9	-0.8	-1.0	0.1	0.8	0.8	0.8	0.8	1.0	-1.1
Age at First Birth	0.5	0.7	1.9	-1.4	-0.8	0.1	-1.1	-0.3	-0.5	-0.9	-1.0	-0.9	0.8
Body Mass Index (BMI) (2010)	0.5	0.7	3.5	1.1	1.3	0.2	-0.1	0.1	-0.1	0.1	-0.2	-0.4	-1.9
Neuroticism (2016)	0.5	0.7	4.4	1.5	-0.2	-0.2	-0.1	0.5	0.2	0.1	-0.2	-0.4	-2.1
Schizophrenia (2014)	0.5	1.2	5.0	0.4	-2.2	-0.1	-1.2	0.4	0.3	0.6	1.2	1.2	1.2
Hand grip strength (left)	0.5	1.4	5.1	-1.5	-2.2	1.2	-0.6	-1.3	-1.1	-1.2	-0.3	-0.6	-0.0
Systolic blood pressure, automated reading	0.5	1.6	5.2	0.5	-2.3	-1.9	0.5	0.7	0.8	0.8	1.5	1.6	0.4
Vitamin and mineral supplements	0.5	0.6	3.3	-0.3	-1.8	-1.2	-0.1	0.1	-0.0	-0.0	0.5	0.7	0.8
Severe depression (siblings)	0.5	0.5	1.3	0.5	-1.1	-0.7	0.2	0.8	0.8	0.7	0.8	0.9	-0.0
Impedance of leg (right)	0.5	2.3	5.5	1.0	-2.4	-1.0	-1.1	1.3	2.2	1.7	1.3	1.9	0.2
Medication: Levothyroxine sodium	0.5	0.9	4.0	-0.6	0.9	-0.3	-0.4	-2.0	-1.6	-0.6	-0.4	-0.2	0.8
Qualifications: None of the above	0.5	1.0	3.2	1.3	-1.8	-0.8	-0.9	0.4	0.4	0.2	0.5	1.2	-1.5
Weight	0.5	2.5	13.1	-0.6	3.6	2.1	0.1	-0.6	-0.8	-0.7	-1.2	-1.8	-0.9
Alcohol intake versus 10 years previously	0.5	0.7	1.8	0.1	1.1	-1.0	-0.7	-0.3	-0.6	-0.7	-0.9	-0.8	-1.3
Happiness	0.5	0.7	4.2	0.5	-0.6	-0.8	-1.0	0.1	0.0	0.0	0.4	0.3	-2.1
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.5	3.0	-0.9	-1.2	0.2	0.0	-0.1	-0.1	-0.0	0.3	-0.2	1.7
Medication: Lansoprazole	0.5	0.6	1.6	0.6	0.3	-0.6	1.2	0.8	1.0	0.4	0.1	0.2	-1.3
Lung cancer (father)	0.5	0.6	2.6	0.8	1.6	0.5	0.4	-0.5	-0.4	-0.4	-0.4	-0.6	-1.0
Arm fat mass (right)	0.5	1.9	11.2	1.5	3.4	0.8	0.8	0.5	0.5	0.7	0.2	-0.3	-1.7
Chronic bronchitis/emphysema (mother)	0.5	0.6	1.9	1.2	1.4	0.2	0.9	0.3	-0.1	0.1	-0.2	-0.4	-1.4
Heart disease (mother)	0.5	0.6	1.8	-1.1	1.4	0.9	-0.3	-0.4	-0.2	-0.0	-0.4	-0.5	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.5	0.6	2.3	0.6	1.4	-0.4	0.8	0.6	0.5	0.0	-0.3	-0.4	-1.5
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.0	3.5	-1.9	0.6	0.6	-0.9	-0.1	-0.4	-0.9	-1.2	-1.1	1.0
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.3	-0.8	0.9	-0.9	-0.2	-0.8	-1.1	-0.8	-0.8	-0.9	-0.3
Friendships satisfaction	0.5	0.6	2.9	-0.1	-1.7	-0.6	-1.1	-0.3	-0.3	-0.1	0.4	0.5	-1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.5	2.4	0.8	-1.5	0.3	0.0	0.8	0.4	0.2	0.6	0.5	-0.8
Arm fat mass (left)	0.5	1.9	12.1	1.3	3.5	0.9	0.9	0.3	0.3	0.6	0.2	-0.4	-1.5
Hearing aid user	0.5	0.6	2.5	0.1	-1.1	-1.6	-1.2	-0.4	-0.6	-0.4	0.0	0.0	-0.1
Medication: Blood pressure	0.5	1.0	1.6	0.6	-0.4	-1.1	1.2	1.3	0.6	1.1	1.3	1.2	1.0
Supplements: Fish oil (including cod liver oil)	0.5	0.6	2.0	0.5	-0.6	1.0	1.4	0.6	0.7	0.6	0.6	0.6	0.9
Age started oral contraceptive pill	0.5	0.7	4.0	-1.1	-0.3	-0.5	-0.3	-0.3	-0.3	-0.5	-0.6	-0.1	2.0
Heart disease (siblings)	0.5	0.6	1.7	-0.7	0.9	1.1	-1.3	-0.5	-0.1	-0.0	-0.4	-0.4	1.2
Bipolar Disorder or Schizophrenia	0.4	0.9	5.3	-0.6	-1.3	-0.1	-2.3	-0.4	-0.6	-0.6	-0.3	-0.1	0.7
Major Depression (MDD)	0.4	0.4	1.1	1.0	0.1	-0.2	0.4	0.6	0.8	0.8	0.6	0.5	-0.8
Height	0.4	7.8	27.2	-5.2	-0.6	3.4	-1.0	-1.7	-2.2	-2.5	-3.1	-3.1	2.0
Hand grip strength (right)	0.4	1.0	4.0	-0.8	-1.5	2.0	1.1	-0.1	0.1	0.0	0.7	0.3	1.4
Multivitamins +/- minerals	0.4	0.5	2.5	0.5	1.1	1.6	-0.3	0.3	0.4	0.4	-0.0	-0.3	-0.7
Supplements: Glucosamine	0.4	0.5	2.4	0.6	1.0	0.6	1.5	-0.0	0.6	0.3	-0.2	0.0	-0.2
Trunk fat mass	0.4	1.7	8.0	1.4	2.8	0.7	0.3	0.9	1.2	1.3	0.6	0.2	-1.2
Frequency of tenseness / restlessness in last 2 weeks	0.4	0.6	4.8	0.6	0.3	-0.9	-0.1	0.3	0.4	0.1	-0.1	0.0	-2.2
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.1	-1.2	1.0	0.5	0.3	0.3	-0.4	-0.8	-1.1	-1.4	-0.7
Tense / ‘highly strung’	0.4	0.7	2.6	0.6	-1.6	-0.6	0.0	1.0	0.9	0.4	0.2	0.7	-1.0
Qualifications: O levels/GCSEs or equivalent	0.4	0.7	2.2	-1.5	0.5	1.0	0.4	-0.5	-0.5	-0.6	-0.7	-0.9	1.3
Medication for cholesterol, blood pressure or diabetes	0.4	0.7	1.5	-0.4	-1.0	1.2	-0.1	-1.1	-1.2	-0.9	-0.5	-0.8	0.3
Number of children fathered	0.4	0.5	1.1	-0.2	1.0	1.0	-0.1	-0.2	0.1	-0.3	-1.0	-1.0	-0.7
Whole body fat mass	0.4	1.8	10.7	1.2	3.3	1.1	0.5	0.5	0.8	0.9	0.3	-0.2	-1.4
Diabetes diagnosed by doctor	0.4	0.7	1.4	1.0	1.2	0.4	1.2	-0.1	0.2	0.7	1.2	0.8	-0.7
Eye problems/disorders: Cataract	0.4	0.5	1.6	-0.4	0.5	-1.2	-0.6	-0.0	-0.7	-0.8	-0.7	-0.9	-0.3
Back pain experienced in last month	0.4	0.7	3.9	0.2	0.8	0.8	0.9	-0.2	-0.2	-0.1	-0.3	-0.6	-2.0
Breast cancer (self-reported)	0.4	0.5	2.6	-0.6	-0.9	-1.6	0.3	0.3	-0.1	-0.7	-0.6	0.1	0.4
Commuting to job workplace: Public transport	0.4	0.5	1.6	0.8	0.0	-0.9	-0.2	1.3	0.7	0.5	0.5	0.6	-0.0
Pain type(s) experienced in last month: Hip pain	0.4	0.5	1.8	-0.1	0.4	1.4	1.1	-0.1	0.4	0.4	0.2	0.4	1.2
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.0	0.5	-0.2	1.0	0.9	0.1	0.3	0.5	0.9	0.7	0.3
High blood pressure	0.3	0.8	3.3	0.5	0.7	-1.8	1.1	1.0	0.7	0.7	0.4	0.6	-0.9
High blood pressure (mother)	0.3	0.4	2.3	-0.0	1.5	-0.2	0.4	-0.2	-0.3	0.0	-0.2	-0.4	-0.9
Financial difficulties in last 2 years	0.3	0.4	1.1	0.5	0.8	0.9	-0.0	-1.1	-0.7	-0.3	-0.2	-0.5	-0.8
Depression (self-reported)	0.3	0.4	1.3	0.6	-0.3	-1.1	0.1	0.5	0.9	0.7	0.5	0.5	-0.7
Illnesses of mother	0.3	0.4	1.2	-0.7	0.2	1.1	0.2	-0.6	-0.5	-0.6	-0.4	-0.5	0.7
Standing height	0.3	2.7	9.4	-3.1	-2.2	1.4	-1.4	-0.1	-0.6	-1.0	-1.2	-0.9	2.3
Length of working week for main job	0.3	0.3	0.8	0.2	0.7	-0.3	0.5	0.9	0.9	0.3	-0.1	-0.1	-0.5
Hair/balding pattern: Pattern 4	0.3	0.6	4.5	0.5	0.0	-2.1	-0.4	0.0	-0.5	-0.6	-0.0	-0.2	-0.7
Gout (self-reported)	0.3	0.4	1.4	0.1	1.2	0.6	-0.4	-0.3	-0.4	-0.4	-0.7	-0.6	-0.6
Medication: Amlodipine	0.3	0.5	1.1	-0.2	0.8	0.1	0.0	-0.2	-0.8	-0.8	-0.9	-0.8	-1.1
Health satisfaction	0.3	0.4	0.8	0.8	0.9	-0.2	-0.2	0.7	0.8	0.7	0.1	0.3	-0.7
Had major operations	0.3	0.3	0.8	0.9	0.5	-0.2	0.4	0.9	0.6	0.6	0.5	0.3	0.4
Hypertension (Self-reported)	0.3	0.7	2.7	0.2	1.0	-1.7	1.2	0.9	0.6	0.5	0.1	0.3	-0.8
Qualifications: nursing, teaching	0.3	0.5	1.7	-0.9	1.3	1.0	-0.1	-0.7	-0.5	-0.6	-0.4	-0.7	0.2
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	2.0	0.4	0.4	0.8	1.3	0.2	-0.2	0.1	0.4	0.1	-1.4
Illnesses of father: None of the above (group 1)	0.3	0.3	2.1	-0.3	-1.4	-0.4	-0.7	-0.2	-0.1	-0.1	0.2	0.1	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	4.2	-0.5	0.5	2.1	0.4	-0.5	-0.5	-0.5	-0.4	-0.7	0.3
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.2	0.1	-1.1	-0.8	-0.3	0.3	0.2	-0.2	-0.1	0.1	-1.1
Unable to work because of sickness or disability	0.3	0.4	1.8	-0.3	1.1	1.3	0.2	-0.5	-0.0	0.4	-0.1	0.1	0.1
Deep venous thrombosis (DVT) (self-reported)	0.3	0.4	1.3	-0.5	-1.1	-0.6	-1.0	-0.1	-0.5	-0.2	0.3	0.2	0.8
Ulcerative Colitis	0.2	0.2	1.5	-0.1	0.1	-0.0	0.7	-0.2	-0.2	0.1	0.1	0.3	1.2
Blood Red Count	0.2	2.2	8.3	-1.0	2.6	0.8	2.9	1.1	1.0	0.8	0.8	0.3	1.4
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	1.1	0.9	-0.3	1.1	0.1	0.3	-0.0	0.0	0.2	0.1	-0.7
Breastfed as a baby	0.2	0.3	2.5	0.1	-1.6	-0.3	0.3	-0.2	-0.2	-0.3	0.1	0.2	0.3
Ever highly irritable/argumentative for 2 days	0.2	0.3	0.9	0.7	0.2	0.5	-0.0	0.3	0.4	0.6	0.9	0.8	-0.0
Blood clot in the leg (DVT)	0.2	0.2	0.7	-0.5	-0.7	-0.5	-0.8	-0.2	-0.5	-0.3	0.0	-0.1	0.6
Medication: Allopurinol	0.2	0.3	1.2	-0.3	1.1	0.4	-0.1	-0.4	-0.6	-0.3	-0.6	-0.5	0.4
Medication: Omeprazole	0.2	0.3	0.9	-0.2	-0.0	-0.9	-1.0	0.6	0.2	-0.3	-0.4	-0.3	-0.3
Medication: Aspirin	0.2	0.2	0.8	-0.8	-0.1	-0.6	-0.1	-0.1	-0.2	-0.4	-0.4	-0.1	0.9
Medication: Aspirin	0.2	0.3	0.9	-0.9	-0.2	-0.5	0.0	-0.4	-0.5	-0.6	-0.4	-0.2	0.9
Medication: Gliclazide	0.2	0.3	1.5	0.4	-0.5	-1.2	0.3	-0.0	0.1	-0.1	0.3	0.5	-0.6
Myopia	0.2	0.3	1.0	-0.4	-0.5	0.7	1.0	-0.2	-0.5	-0.4	0.3	0.1	0.7
Vascular/heart problems diagnosed by doctor	0.2	0.4	2.7	0.4	-1.0	1.6	-0.0	-0.4	-0.3	-0.1	0.5	0.1	0.4
Hair Pigment	0.1	1.4	3.8	0.2	1.0	1.2	1.9	-0.5	-0.7	-0.9	-1.2	-1.4	-1.8
Tanning	0.1	1.0	6.4	0.2	-2.5	0.3	0.4	-1.2	-1.0	-0.4	0.7	0.4	-0.6
Mouth/teeth dental problems: Bleeding gums	0.1	0.2	0.7	-0.2	-0.2	0.8	-0.2	-0.4	-0.5	-0.3	-0.5	-0.3	-0.1
Qualifications: College or University degree	0.1	0.4	1.6	-1.2	0.6	0.1	-0.6	0.4	0.3	-0.1	-0.0	-0.4	1.3
Comparative height size at age 10	0.1	0.5	1.0	-1.0	1.0	0.9	0.1	0.4	0.1	-0.1	-1.0	-0.7	-0.5
Medication: Bendroflumethiazide	0.1	0.2	0.6	-0.0	0.2	-0.8	0.5	0.5	0.1	0.3	0.2	0.3	0.6
Serious illness, injury or assault to yourself	0.0	0.0	0.1	0.3	0.3	0.3	-0.4	-0.1	-0.0	-0.1	-0.0	0.0	-0.2

Hub : Genes

FAM117B

Models

Trait associations