Best TWAS P=6.72e-14 · Best GWAS P=2.99e-12 conditioned to 2.11e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | POLR2B | 0.09 | 0.05 | bslmm | 572 | 0.02 | 4.7e-04 | -6.8 | -7.5 | 6.7e-14 | 0.41 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Artery Tibial | NOA1 | 0.22 | 0.08 | lasso | 5 | 0.12 | 1.6e-09 | -6.8 | 5.9 | 4.5e-09 | -0.77 | 0.02 | 0.98 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | REST | 0.04 | 0.02 | bslmm | 536 | 0.02 | 3.4e-03 | 4.4 | 5.8 | 8.7e-09 | -0.38 | 0.08 | 0.80 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | C4orf14 | 0.07 | 0.05 | blup | 57 | 0.06 | 3.2e-06 | -3.2 | 6.0 | 2.5e-09 | -0.80 | 0.02 | 0.97 | FALSE |