[Hub]/) : Traits : Impedance of arm (right) :

chr4:102,852,939-104,815,937

Best TWAS P=1.26e-13 · Best GWAS P=1.28e-10 conditioned to 0.164

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CENPE 0.10 0.10 lasso 14 0.11 5.8e-13 5.61 5.7 9.6e-09 0.47 0.79 0.21 FALSE
2 CommonMind Brain Pre-frontal Cortex MANBA 0.08 0.04 bslmm 390 0.03 9.6e-05 -5.44 5.4 6.1e-08 0.62 0.58 0.38 FALSE
3 CommonMind Brain Pre-frontal Cortex SLC9B1 0.13 0.23 enet 24 0.24 4.4e-29 6.43 -6.5 7.6e-11 -0.93 0.04 0.96 FALSE
4 GTEx Adipose Subcutaneous CISD2 0.06 0.09 enet 12 0.06 7.3e-06 6.27 -6.2 5.4e-10 -0.97 0.06 0.94 FALSE
5 GTEx Adipose Visceral Omentum UBE2D3 0.07 0.00 enet 23 0.02 3.2e-02 6.31 -6.6 5.3e-11 -0.68 0.06 0.72 FALSE
6 GTEx Adrenal Gland CISD2 0.08 0.03 lasso 2 0.03 4.1e-02 6.33 -6.6 4.9e-11 -0.94 0.05 0.86 FALSE
7 GTEx Artery Aorta UBE2D3 0.07 0.06 lasso 5 0.04 3.5e-03 6.31 -6.3 2.8e-10 -0.97 0.06 0.91 FALSE
8 GTEx Artery Aorta CISD2 0.10 0.08 lasso 4 0.06 1.8e-04 6.29 -6.3 2.5e-10 -0.99 0.05 0.94 FALSE
9 GTEx Artery Coronary CISD2 0.14 0.15 lasso 8 0.12 7.4e-05 -5.56 -6.3 3.9e-10 -0.94 0.06 0.90 FALSE
10 GTEx Artery Tibial CISD2 0.11 0.12 lasso 4 0.10 3.1e-08 6.38 -6.2 5.2e-10 -0.98 0.05 0.95 FALSE
11 GTEx Brain Cerebellum MANBA 0.18 0.03 enet 27 0.05 1.2e-02 5.71 -5.7 1.0e-08 -0.59 0.07 0.34 FALSE
12 GTEx Brain Cerebellum CISD2 0.13 0.18 lasso 3 0.17 1.1e-05 6.31 -6.3 2.4e-10 -0.98 0.05 0.94 FALSE
13 GTEx Breast Mammary Tissue CISD2 0.21 0.08 enet 13 0.08 6.0e-05 6.25 -6.0 2.0e-09 -0.89 0.06 0.94 FALSE
14 GTEx Breast Mammary Tissue (Male) CISD2 0.15 0.02 lasso 3 -0.01 6.5e-01 6.39 -6.2 4.2e-10 -0.97 0.04 0.40 FALSE
15 GTEx Breast Mammary Tissue (Female) CISD2 0.12 0.04 enet 12 0.07 5.0e-03 6.07 -5.9 4.1e-09 -0.83 0.06 0.77 FALSE
16 GTEx Cells Transformed fibroblasts MANBA 0.26 0.22 lasso 9 0.27 1.9e-20 5.46 6.4 1.9e-10 0.74 0.86 0.14 FALSE
17 GTEx Cells Transformed fibroblasts UBE2D3 0.11 0.09 enet 13 0.08 2.3e-06 6.25 -6.3 3.9e-10 -0.99 0.05 0.95 FALSE
18 GTEx Cells Transformed fibroblasts CISD2 0.16 0.17 enet 12 0.13 9.7e-10 6.11 -5.9 3.1e-09 -0.96 0.06 0.94 FALSE
19 GTEx Colon Sigmoid CISD2 0.20 0.24 enet 15 0.13 2.1e-05 6.27 -6.9 3.9e-12 -0.95 0.06 0.94 FALSE
20 GTEx Esophagus Gastroesophageal Junction CISD2 0.10 0.05 enet 6 0.04 1.6e-02 -5.56 -5.8 6.1e-09 -0.98 0.06 0.82 FALSE
21 GTEx Esophagus Mucosa CISD2 0.12 0.06 enet 13 0.05 2.1e-04 6.32 -5.9 3.0e-09 -0.98 0.06 0.94 FALSE
22 GTEx Esophagus Muscularis CISD2 0.19 0.22 enet 25 0.21 6.2e-13 6.07 -6.5 9.7e-11 -0.94 0.06 0.94 FALSE
23 GTEx Lung CISD2 0.06 0.05 enet 10 0.04 5.4e-04 6.11 -6.0 1.6e-09 -0.89 0.05 0.94 FALSE
24 GTEx Muscle Skeletal UBE2D3 0.03 0.00 enet 21 0.00 3.8e-01 6.11 -5.3 9.3e-08 -0.68 0.06 0.66 FALSE
25 GTEx Muscle Skeletal CISD2 0.03 0.02 enet 15 0.03 7.9e-04 -5.44 -6.0 2.4e-09 -0.79 0.14 0.82 FALSE
26 GTEx Nerve Tibial CISD2 0.19 0.14 enet 43 0.14 7.5e-10 6.24 -5.3 1.2e-07 -0.78 0.06 0.94 FALSE
27 GTEx Ovary CISD2 0.12 0.12 lasso 4 0.07 6.9e-03 6.11 -6.1 1.4e-09 -0.96 0.06 0.76 FALSE
28 GTEx Pancreas UBE2D3 0.13 0.09 enet 12 0.12 6.7e-06 5.00 -6.2 5.5e-10 -0.88 0.05 0.94 FALSE
29 GTEx Pancreas BDH2 0.16 0.05 enet 10 0.10 4.9e-05 5.70 5.2 2.4e-07 0.45 0.67 0.31 FALSE
30 GTEx Skin Not Sun Exposed Suprapubic UBE2D3 0.11 0.00 enet 17 0.00 2.5e-01 -0.27 -6.1 1.1e-09 -0.67 0.06 0.76 FALSE
31 GTEx Skin Not Sun Exposed Suprapubic CISD2 0.13 0.14 enet 18 0.10 6.0e-06 6.28 -5.9 2.9e-09 -0.96 0.05 0.95 FALSE
32 GTEx Skin Sun Exposed Lower leg CISD2 0.12 0.20 lasso 14 0.20 1.1e-16 6.22 -6.2 4.9e-10 -0.99 0.05 0.95 FALSE
33 GTEx Small Intestine Terminal Ileum CISD2 0.29 0.19 enet 34 0.15 3.2e-04 6.33 -5.9 3.0e-09 -0.92 0.06 0.84 FALSE
34 GTEx Spleen MANBA 0.29 0.23 enet 11 0.30 2.3e-08 5.50 -5.7 9.6e-09 -0.59 0.66 0.24 FALSE
35 GTEx Testis CISD2 0.10 0.04 lasso 5 0.03 1.3e-02 6.32 -5.5 3.9e-08 -0.93 0.05 0.87 FALSE
36 GTEx Testis RP11-10L12.4 0.13 0.05 enet 15 0.14 1.3e-06 1.15 -5.1 2.9e-07 -0.77 0.08 0.74 FALSE
37 GTEx Thyroid CISD2 0.12 0.07 lasso 3 0.05 8.8e-05 6.11 -6.1 1.3e-09 -0.97 0.05 0.94 FALSE
38 GTEx Uterus CISD2 0.34 0.22 enet 25 0.19 8.9e-05 6.11 -6.4 1.8e-10 -0.92 0.05 0.90 FALSE
39 METSIM Adipose UBE2D3 0.04 0.02 bslmm 332 0.03 2.0e-05 6.34 -5.1 3.1e-07 -0.81 0.07 0.91 FALSE
40 NTR Blood MANBA 0.01 0.00 bslmm 390 0.01 3.1e-03 5.54 6.1 1.1e-09 0.64 0.09 0.15 FALSE
41 ROSMAP Brain Pre-frontal Cortex MANBA 0.20 0.30 enet 26 0.31 2.3e-40 6.04 -6.3 2.7e-10 -0.70 0.20 0.80 FALSE
42 ROSMAP Brain Pre-frontal Cortex UBE2D3 0.05 0.06 blup 337 0.07 5.0e-09 6.11 -6.9 5.8e-12 -0.95 0.04 0.96 FALSE
43 ROSMAP Brain Pre-frontal Cortex CENPE 0.06 0.07 lasso 15 0.06 9.4e-09 5.61 6.3 2.3e-10 0.54 0.76 0.24 FALSE
44 ROSMAP Brain Pre-frontal Cortex CISD2 0.15 0.34 lasso 9 0.34 1.2e-44 6.33 -6.4 1.9e-10 -0.98 0.06 0.94 FALSE
45 ROSMAP Brain Pre-frontal Cortex RP11-10L12.4 0.08 0.10 lasso 7 0.09 5.1e-12 6.22 -6.2 7.6e-10 -0.98 0.05 0.95 FALSE
46 The Cancer Genome Atlas Bladder Urothelial Carcinoma MANBA 0.10 0.13 lasso 4 0.11 1.8e-09 5.34 5.5 4.8e-08 0.73 0.60 0.40 FALSE
47 The Cancer Genome Atlas Breast Invasive Carcinoma BDH2 0.02 0.01 lasso 3 0.01 3.3e-03 5.57 5.3 8.8e-08 0.50 0.09 0.41 FALSE
48 The Cancer Genome Atlas Breast Invasive Carcinoma MANBA 0.11 0.16 lasso 4 0.16 3.4e-32 5.34 5.9 4.9e-09 0.72 0.74 0.26 FALSE
49 The Cancer Genome Atlas Colon Adenocarcinoma MANBA 0.33 0.11 enet 13 0.21 2.0e-12 5.22 6.1 1.3e-09 0.78 0.02 0.98 FALSE
50 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CENPE 0.04 0.01 enet 10 0.02 2.6e-03 6.14 -7.4 1.3e-13 -0.74 0.01 0.92 TRUE
51 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MANBA 0.15 0.09 lasso 6 0.09 1.0e-10 5.24 5.6 2.2e-08 0.66 0.54 0.46 FALSE
52 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MANBA 0.03 0.03 blup 71 0.04 2.0e-05 5.50 6.4 1.8e-10 0.84 0.04 0.95 FALSE
53 The Cancer Genome Atlas Brain Lower Grade Glioma UBE2D3 0.02 0.02 enet 6 0.02 3.7e-03 6.35 -5.7 1.1e-08 -0.95 0.02 0.82 FALSE
54 The Cancer Genome Atlas Lung Adenocarcinoma CISD2 0.02 0.02 enet 7 0.02 1.3e-03 -6.06 6.5 5.8e-11 0.87 0.01 0.86 FALSE
55 The Cancer Genome Atlas Lung Adenocarcinoma MANBA 0.13 0.10 blup 69 0.10 4.5e-12 5.34 6.5 9.5e-11 0.79 0.33 0.67 FALSE
56 The Cancer Genome Atlas Pancreatic Adenocarcinoma CISD2 0.05 0.01 blup 18 0.06 1.9e-03 6.30 -6.7 2.5e-11 -0.98 0.01 0.69 FALSE
57 The Cancer Genome Atlas Prostate Adenocarcinoma MANBA 0.11 0.04 lasso 7 0.04 3.5e-05 5.34 5.5 5.0e-08 0.69 0.21 0.77 FALSE
58 The Cancer Genome Atlas Prostate Adenocarcinoma NHEDC2 0.03 0.03 lasso 2 0.01 1.8e-02 6.26 5.7 1.0e-08 0.49 0.02 0.51 FALSE
59 The Cancer Genome Atlas Prostate Adenocarcinoma UBE2D3 0.03 0.04 enet 11 0.03 1.4e-04 6.27 -6.4 1.7e-10 -0.97 0.02 0.97 FALSE
60 The Cancer Genome Atlas Thyroid Carcinoma CISD2 0.05 0.08 enet 5 0.06 1.9e-06 6.24 -6.3 2.7e-10 -0.97 0.01 0.99 FALSE
61 The Cancer Genome Atlas Thyroid Carcinoma MANBA 0.12 0.06 enet 5 0.06 1.9e-06 5.71 6.0 2.0e-09 0.67 0.20 0.79 FALSE