[Hub]/) : Traits : Impedance of arm (right) : ← →

chr4:102,852,939-104,815,937

Best TWAS P=1.26e-13 · Best GWAS P=1.28e-10 conditioned to 0.164

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
50	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CENPE	0.04	0.01	enet	10	0.02	2.6e-03	6.14	-7.4	1.3e-13	-0.74	0.01	0.92	TRUE
19	GTEx	Colon Sigmoid	CISD2	0.20	0.24	enet	15	0.13	2.1e-05	6.27	-6.9	3.9e-12	-0.95	0.06	0.94	FALSE
42	ROSMAP	Brain Pre-frontal Cortex	UBE2D3	0.05	0.06	blup	337	0.07	5.0e-09	6.11	-6.9	5.8e-12	-0.95	0.04	0.96	FALSE
56	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CISD2	0.05	0.01	blup	18	0.06	1.9e-03	6.30	-6.7	2.5e-11	-0.98	0.01	0.69	FALSE
6	GTEx	Adrenal Gland	CISD2	0.08	0.03	lasso	2	0.03	4.1e-02	6.33	-6.6	4.9e-11	-0.94	0.05	0.86	FALSE
5	GTEx	Adipose Visceral Omentum	UBE2D3	0.07	0.00	enet	23	0.02	3.2e-02	6.31	-6.6	5.3e-11	-0.68	0.06	0.72	FALSE
54	The Cancer Genome Atlas	Lung Adenocarcinoma	CISD2	0.02	0.02	enet	7	0.02	1.3e-03	-6.06	6.5	5.8e-11	0.87	0.01	0.86	FALSE
3	CommonMind	Brain Pre-frontal Cortex	SLC9B1	0.13	0.23	enet	24	0.24	4.4e-29	6.43	-6.5	7.6e-11	-0.93	0.04	0.96	FALSE
55	The Cancer Genome Atlas	Lung Adenocarcinoma	MANBA	0.13	0.10	blup	69	0.10	4.5e-12	5.34	6.5	9.5e-11	0.79	0.33	0.67	FALSE
22	GTEx	Esophagus Muscularis	CISD2	0.19	0.22	enet	25	0.21	6.2e-13	6.07	-6.5	9.7e-11	-0.94	0.06	0.94	FALSE
59	The Cancer Genome Atlas	Prostate Adenocarcinoma	UBE2D3	0.03	0.04	enet	11	0.03	1.4e-04	6.27	-6.4	1.7e-10	-0.97	0.02	0.97	FALSE
38	GTEx	Uterus	CISD2	0.34	0.22	enet	25	0.19	8.9e-05	6.11	-6.4	1.8e-10	-0.92	0.05	0.90	FALSE
52	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MANBA	0.03	0.03	blup	71	0.04	2.0e-05	5.50	6.4	1.8e-10	0.84	0.04	0.95	FALSE
16	GTEx	Cells Transformed fibroblasts	MANBA	0.26	0.22	lasso	9	0.27	1.9e-20	5.46	6.4	1.9e-10	0.74	0.86	0.14	FALSE
44	ROSMAP	Brain Pre-frontal Cortex	CISD2	0.15	0.34	lasso	9	0.34	1.2e-44	6.33	-6.4	1.9e-10	-0.98	0.06	0.94	FALSE
43	ROSMAP	Brain Pre-frontal Cortex	CENPE	0.06	0.07	lasso	15	0.06	9.4e-09	5.61	6.3	2.3e-10	0.54	0.76	0.24	FALSE
12	GTEx	Brain Cerebellum	CISD2	0.13	0.18	lasso	3	0.17	1.1e-05	6.31	-6.3	2.4e-10	-0.98	0.05	0.94	FALSE
8	GTEx	Artery Aorta	CISD2	0.10	0.08	lasso	4	0.06	1.8e-04	6.29	-6.3	2.5e-10	-0.99	0.05	0.94	FALSE
41	ROSMAP	Brain Pre-frontal Cortex	MANBA	0.20	0.30	enet	26	0.31	2.3e-40	6.04	-6.3	2.7e-10	-0.70	0.20	0.80	FALSE
60	The Cancer Genome Atlas	Thyroid Carcinoma	CISD2	0.05	0.08	enet	5	0.06	1.9e-06	6.24	-6.3	2.7e-10	-0.97	0.01	0.99	FALSE
7	GTEx	Artery Aorta	UBE2D3	0.07	0.06	lasso	5	0.04	3.5e-03	6.31	-6.3	2.8e-10	-0.97	0.06	0.91	FALSE
9	GTEx	Artery Coronary	CISD2	0.14	0.15	lasso	8	0.12	7.4e-05	-5.56	-6.3	3.9e-10	-0.94	0.06	0.90	FALSE
17	GTEx	Cells Transformed fibroblasts	UBE2D3	0.11	0.09	enet	13	0.08	2.3e-06	6.25	-6.3	3.9e-10	-0.99	0.05	0.95	FALSE
14	GTEx	Breast Mammary Tissue (Male)	CISD2	0.15	0.02	lasso	3	-0.01	6.5e-01	6.39	-6.2	4.2e-10	-0.97	0.04	0.40	FALSE
32	GTEx	Skin Sun Exposed Lower leg	CISD2	0.12	0.20	lasso	14	0.20	1.1e-16	6.22	-6.2	4.9e-10	-0.99	0.05	0.95	FALSE
10	GTEx	Artery Tibial	CISD2	0.11	0.12	lasso	4	0.10	3.1e-08	6.38	-6.2	5.2e-10	-0.98	0.05	0.95	FALSE
4	GTEx	Adipose Subcutaneous	CISD2	0.06	0.09	enet	12	0.06	7.3e-06	6.27	-6.2	5.4e-10	-0.97	0.06	0.94	FALSE
28	GTEx	Pancreas	UBE2D3	0.13	0.09	enet	12	0.12	6.7e-06	5.00	-6.2	5.5e-10	-0.88	0.05	0.94	FALSE
45	ROSMAP	Brain Pre-frontal Cortex	RP11-10L12.4	0.08	0.10	lasso	7	0.09	5.1e-12	6.22	-6.2	7.6e-10	-0.98	0.05	0.95	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	UBE2D3	0.11	0.00	enet	17	0.00	2.5e-01	-0.27	-6.1	1.1e-09	-0.67	0.06	0.76	FALSE
40	NTR	Blood	MANBA	0.01	0.00	bslmm	390	0.01	3.1e-03	5.54	6.1	1.1e-09	0.64	0.09	0.15	FALSE
37	GTEx	Thyroid	CISD2	0.12	0.07	lasso	3	0.05	8.8e-05	6.11	-6.1	1.3e-09	-0.97	0.05	0.94	FALSE
49	The Cancer Genome Atlas	Colon Adenocarcinoma	MANBA	0.33	0.11	enet	13	0.21	2.0e-12	5.22	6.1	1.3e-09	0.78	0.02	0.98	FALSE
27	GTEx	Ovary	CISD2	0.12	0.12	lasso	4	0.07	6.9e-03	6.11	-6.1	1.4e-09	-0.96	0.06	0.76	FALSE
23	GTEx	Lung	CISD2	0.06	0.05	enet	10	0.04	5.4e-04	6.11	-6.0	1.6e-09	-0.89	0.05	0.94	FALSE
13	GTEx	Breast Mammary Tissue	CISD2	0.21	0.08	enet	13	0.08	6.0e-05	6.25	-6.0	2.0e-09	-0.89	0.06	0.94	FALSE
61	The Cancer Genome Atlas	Thyroid Carcinoma	MANBA	0.12	0.06	enet	5	0.06	1.9e-06	5.71	6.0	2.0e-09	0.67	0.20	0.79	FALSE
25	GTEx	Muscle Skeletal	CISD2	0.03	0.02	enet	15	0.03	7.9e-04	-5.44	-6.0	2.4e-09	-0.79	0.14	0.82	FALSE
31	GTEx	Skin Not Sun Exposed Suprapubic	CISD2	0.13	0.14	enet	18	0.10	6.0e-06	6.28	-5.9	2.9e-09	-0.96	0.05	0.95	FALSE
21	GTEx	Esophagus Mucosa	CISD2	0.12	0.06	enet	13	0.05	2.1e-04	6.32	-5.9	3.0e-09	-0.98	0.06	0.94	FALSE
33	GTEx	Small Intestine Terminal Ileum	CISD2	0.29	0.19	enet	34	0.15	3.2e-04	6.33	-5.9	3.0e-09	-0.92	0.06	0.84	FALSE
18	GTEx	Cells Transformed fibroblasts	CISD2	0.16	0.17	enet	12	0.13	9.7e-10	6.11	-5.9	3.1e-09	-0.96	0.06	0.94	FALSE
15	GTEx	Breast Mammary Tissue (Female)	CISD2	0.12	0.04	enet	12	0.07	5.0e-03	6.07	-5.9	4.1e-09	-0.83	0.06	0.77	FALSE
48	The Cancer Genome Atlas	Breast Invasive Carcinoma	MANBA	0.11	0.16	lasso	4	0.16	3.4e-32	5.34	5.9	4.9e-09	0.72	0.74	0.26	FALSE
20	GTEx	Esophagus Gastroesophageal Junction	CISD2	0.10	0.05	enet	6	0.04	1.6e-02	-5.56	-5.8	6.1e-09	-0.98	0.06	0.82	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CENPE	0.10	0.10	lasso	14	0.11	5.8e-13	5.61	5.7	9.6e-09	0.47	0.79	0.21	FALSE
34	GTEx	Spleen	MANBA	0.29	0.23	enet	11	0.30	2.3e-08	5.50	-5.7	9.6e-09	-0.59	0.66	0.24	FALSE
11	GTEx	Brain Cerebellum	MANBA	0.18	0.03	enet	27	0.05	1.2e-02	5.71	-5.7	1.0e-08	-0.59	0.07	0.34	FALSE
58	The Cancer Genome Atlas	Prostate Adenocarcinoma	NHEDC2	0.03	0.03	lasso	2	0.01	1.8e-02	6.26	5.7	1.0e-08	0.49	0.02	0.51	FALSE
53	The Cancer Genome Atlas	Brain Lower Grade Glioma	UBE2D3	0.02	0.02	enet	6	0.02	3.7e-03	6.35	-5.7	1.1e-08	-0.95	0.02	0.82	FALSE
51	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MANBA	0.15	0.09	lasso	6	0.09	1.0e-10	5.24	5.6	2.2e-08	0.66	0.54	0.46	FALSE
35	GTEx	Testis	CISD2	0.10	0.04	lasso	5	0.03	1.3e-02	6.32	-5.5	3.9e-08	-0.93	0.05	0.87	FALSE
46	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	MANBA	0.10	0.13	lasso	4	0.11	1.8e-09	5.34	5.5	4.8e-08	0.73	0.60	0.40	FALSE
57	The Cancer Genome Atlas	Prostate Adenocarcinoma	MANBA	0.11	0.04	lasso	7	0.04	3.5e-05	5.34	5.5	5.0e-08	0.69	0.21	0.77	FALSE
2	CommonMind	Brain Pre-frontal Cortex	MANBA	0.08	0.04	bslmm	390	0.03	9.6e-05	-5.44	5.4	6.1e-08	0.62	0.58	0.38	FALSE
47	The Cancer Genome Atlas	Breast Invasive Carcinoma	BDH2	0.02	0.01	lasso	3	0.01	3.3e-03	5.57	5.3	8.8e-08	0.50	0.09	0.41	FALSE
24	GTEx	Muscle Skeletal	UBE2D3	0.03	0.00	enet	21	0.00	3.8e-01	6.11	-5.3	9.3e-08	-0.68	0.06	0.66	FALSE
26	GTEx	Nerve Tibial	CISD2	0.19	0.14	enet	43	0.14	7.5e-10	6.24	-5.3	1.2e-07	-0.78	0.06	0.94	FALSE
29	GTEx	Pancreas	BDH2	0.16	0.05	enet	10	0.10	4.9e-05	5.70	5.2	2.4e-07	0.45	0.67	0.31	FALSE
36	GTEx	Testis	RP11-10L12.4	0.13	0.05	enet	15	0.14	1.3e-06	1.15	-5.1	2.9e-07	-0.77	0.08	0.74	FALSE
39	METSIM	Adipose	UBE2D3	0.04	0.02	bslmm	332	0.03	2.0e-05	6.34	-5.1	3.1e-07	-0.81	0.07	0.91	FALSE